Search results for "Adduct"

showing 10 items of 320 documents

Enzymatic esterification of bicyclic meso-diols derived from 1,4-bis(hydroxymethyl)furan. An enantioselective Diels–Alder reaction equivalent

1998

Abstract meso -Diols derived from the Diels–Alder adduct 1,4-bis(hydroxymethyl)furan/dimethyl acetylenedicarboxylate can be enantioselectively monoacetylated under CRL or PSL catalysis with very good yields and moderate to excellent ees. (+)-Monoacetates are always preferentially formed in the reactions catalyzed by CRL, and their (−)-enantiomers are the main products in the acetylations under PSL catalysis. Absolute configurations have been determined by X-ray analysis of a single crystal of an ( R )-α-methoxyphenylacetyl derivative.

Dimethyl acetylenedicarboxylateBicyclic moleculeChemistryOrganic ChemistryEnantioselective synthesisMedicinal chemistryCatalysisAdductInorganic Chemistrychemistry.chemical_compoundFuranHydroxymethylPhysical and Theoretical ChemistryDerivative (chemistry)Diels–Alder reactionTetrahedron: Asymmetry
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Triazolopyridines. Part 11. Ylides derived from 2-Acylmethyltriazolopyridinium salts.

1991

Abstract Ylides derived from 2-acylmethyltriazolopyridinium salts (2a) -(2c) react with methyl or ethyl propiolate and with dimethyl acetylenedicarboxylate to give ylides (3a)–(3e), (6) or (7). In some cases 1:2 adducts are formed, shown to be the novel ylides (8a)–(8d); an X-ray diffraction confirms structure (8a).

Dimethyl acetylenedicarboxylateBicyclic moleculeOrganic ChemistryCrystal structureNuclear magnetic resonance spectroscopyBiochemistryMedicinal chemistryAdductEthyl propiolatechemistry.chemical_compoundchemistryDrug DiscoveryX-ray crystallographyMichael reactionTetrahedron
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Cycloaddition reactions. A new type of cycloadduct from a substituted 2-vinylthiophen and dmad

1987

Abstract Cycloaddition reactions between 2-(1-cyanoallyl)thiophen and the dienophiles diethyl azodicarboxylate, N-phenylmaleimide , methyl propiolate, and dimethyl acetylenedicarboxylate are reported. Products include simple benzo[b] thiophen carboxylates (13,19) and reduced derivatives (8,9,10,12,18), as a mixture of diastereoisomers, except in the adduct with diethyl azodicarboxylate. With dimethyl acetylenedicarboxylate a new type of tricyclic compound was also found (20).

Dimethyl acetylenedicarboxylateBicyclic moleculeOrganic ChemistryDiastereomerNuclear magnetic resonance spectroscopyBiochemistryCycloadditionAdductDiethyl azodicarboxylatechemistry.chemical_compoundchemistryDrug DiscoveryOrganic chemistryAliphatic compoundTetrahedron
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ChemInform Abstract: Triazolopyridines. Part 11. Ylides Derived from 2- Acylmethyltriazolopyridinium Salts.

2010

Abstract Ylides derived from 2-acylmethyltriazolopyridinium salts (2a) -(2c) react with methyl or ethyl propiolate and with dimethyl acetylenedicarboxylate to give ylides (3a)–(3e), (6) or (7). In some cases 1:2 adducts are formed, shown to be the novel ylides (8a)–(8d); an X-ray diffraction confirms structure (8a).

Dimethyl acetylenedicarboxylateEthyl propiolatechemistry.chemical_compoundChemistryOrganic chemistryGeneral MedicineMedicinal chemistryAdductChemInform
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ChemInform Abstract: Synthesis and Chemical Reactivity of 5-Methoxy-2-vinyl-4-azaindoles.

2010

Abstract 2-Vinyl-4-azaindoles are less reactive with dienophiles than 2-vinylindoles. 5-Methoxy-2-vinyl-4-azaindole 2a and its 1-methyl derivative 2a reacts with N-phenylmaleimide to yield cycloadducts only under vigorous conditions. 2b produces a cycloadduct with dimethyl acetylenedicarboxylate, while 2a yields a Michael-type adduct. Reactions with more reactive dienophiles gave only polymeric products.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundAddition reactionchemistryYield (chemistry)technology industry and agricultureGeneral MedicineMedicinal chemistryDerivative (chemistry)AdductChemInform
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ChemInform Abstract: Carbazole Synthesis via an in situ Trapping Strategy with Indolyl Enol Ethers.

2010

Indolyl enol ethers, generated from the alkoxy(indolyl)carbenium tetra- fluoroborates (1) by treatment with sodium hydride, can be trapped with dimethyl acetylenedicarboxylate or N-phenylmaleimide to furnish the se- lectively functionalized carbazoles (3), (4), (5), (9), (10), and (13). In addition, the biaryl derivatives (6) and (11) are produced by a ring- opening reaction of the primarily formed Diels-Alder adduct. In the case of the biaryl derivative (6), an X-ray crystal structure analysis yields valuable information on constitutions and configurations in the biaryl series. The phenomenon of atropisomerism is discussed for this compound

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundAtropisomerChemistryCarbazoleAlkoxy groupGeneral MedicineRing (chemistry)EnolMedicinal chemistryAdductSodium hydrideChemInform
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Synthesis and Chemical Reactivity of 5-Methoxy-2-vinyl-4-azaindoles

1997

Abstract 2-Vinyl-4-azaindoles are less reactive with dienophiles than 2-vinylindoles. 5-Methoxy-2-vinyl-4-azaindole 2a and its 1-methyl derivative 2a reacts with N-phenylmaleimide to yield cycloadducts only under vigorous conditions. 2b produces a cycloadduct with dimethyl acetylenedicarboxylate, while 2a yields a Michael-type adduct. Reactions with more reactive dienophiles gave only polymeric products.

Dimethyl acetylenedicarboxylatechemistry.chemical_compoundchemistryYield (chemistry)Organic Chemistrytechnology industry and agricultureOrganic chemistryDerivative (chemistry)AdductSynthetic Communications
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Syntheses and catalytic oxotransfer activities of oxo molybdenum(vi) complexes of a new aminoalcohol phenolate ligand.

2017

The new aminoalcohol phenol 2,4-di-tert-butyl-6-(((2-hydroxy-2-phenylethyl)amino)methyl)phenol (H2L) was prepared by a facile solvent-free synthesis and used as a tridentate ligand for new cis-dioxomolybdenum(vi)(L) complexes. In the presence of a coordinating solvent (DMSO, MeOH, pyridine), the complexes crystallise as monomeric solvent adducts while in the absence of such molecules, a trimer with asymmetric Mo[double bond, length as m-dash]O→Mo bridges crystallises. The complexes can catalyse epoxidation of cis-cyclooctene and sulfoxidation of methyl-p-tolylsulfide, using tert-butyl hydroperoxide as oxidant.

Double bondTrimer010402 general chemistry01 natural sciencesMedicinal chemistrycatalystsCatalysisAdductInorganic Chemistrychemistry.chemical_compoundkatalyytitmolybdenumPyridineOrganic chemistrycoordination complexesta116chemistry.chemical_classificationkemiallinen synteesi010405 organic chemistryLigandkompleksiyhdisteet0104 chemical sciencesSolventMonomerchemistrymolybdeenichemical synthesisDalton transactions (Cambridge, England : 2003)
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The Pd3(dppm)3(CO)2+ Cluster: An Efficient Electrochemically Assisted Lewis Acid Catalyst for the Fluorination and Alcoholysis of Acyl Chlorides.

2002

The dicationic palladium cluster Pd3(dppm)3(CO)2+ (dppm = bis(diphenylphosphino)methane) reacts with acid chlorides RCOCl (R = n-C6H13, t-Bu, Ph) to afford quantitatively the chloride adduct Pd3(dppm)3(CO)(Cl)+ and the acyl cation RCO+ as the organic counterpart. The dicationic reactive cluster can be reformed by electrolyzing the chloride complex with a copper anode leaving CuCl as a byproduct. The combination of these two reactions provides an electrocatalytic way to form the acylium from the acid chloride. Indeed, in CH2Cl2, 0.2 M NBu4PF6, or NBu4BF4, the electrolysis of the acid chloride in the presence of a catalytic amount of the cluster (1%) gives in good yields the acid fluoride RCO…

ElectrolysisSupporting electrolyteOrganic ChemistryInorganic chemistrychemistry.chemical_elementGeneral MedicineElectrochemistryMedicinal chemistryChlorideAdductlaw.inventionLewis acid catalysisCatalysischemistry.chemical_compoundAcyl chloridechemistryNucleophilelawmedicineLewis acids and basesPalladiummedicine.drugChemInform
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Measurement of white wines resistance against oxidation by Electron Paramagnetic Resonance spectroscopy

2018

International audience; Free radical theory of aging hypothesizes that oxygen-derived radicals are responsible for the storage-related flavor instability in wine. In an optimal situation, a balanced-distribution exists between oxidants and antioxidants among wines intrinsic/extrinsic metabolites. Based on the kinetic study of POBN-1-hydroxyethyl spin adduct (POBN-1-HER) formation in wines initiated via the Fenton reaction, a novel tool based on EPR spin trapping methodology was developed to quantify wines resistance against oxidation. Antioxidant capacities of wines were evaluated according to POBN-1-HER maximum signal intensity (Imax POBN-1-HER) and rate formation (r(POBN-1-HER)) kinetic p…

Electron paramagnetic resonance spectroscopyAntioxidantFree Radicalssulfur-dioxidemedicine.medical_treatmentRadicalWinePhotochemistry01 natural sciencesAnalytical ChemistryAdductlaw.invention0404 agricultural biotechnologylaw[SDV.IDA]Life Sciences [q-bio]/Food engineeringmedicineAging potentialElectron paramagnetic resonanceFlavorFree-radical theory of agingdegradationWineparametersChemistryfree-radical generation010401 analytical chemistryRadical chemistryElectron Spin Resonance Spectroscopyfood and beveragesPolyphenolstemperature04 agricultural and veterinary sciencesGeneral Medicine040401 food science0104 chemical sciencescolorElectron Paramagnetic ResonancearomaSulfur dioxideidentificationSpin Labelsepr spectroscopyOxidation-ReductionFood Science
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