Search results for "Enone"
showing 10 items of 320 documents
Über die Synthese von o-Acylamino-ß-dimethylamino-propiophenonen 1. Mitt.: Verhalten von o-Nitro- und o-Carbäthoxyamino-acetophenon bei der Mannich-R…
1970
Das bei der Mannich-Reaktion von o-Carbathoxyamino-acetophenon mit Paraformaldehyd und Dimethylamin-hydrochlorid erhaltene Kondensationsprodukt wurde als ein Gemisch von o-Carbathoxyamino-β-dimethylamino-propiophenon und o-Carbathoxyamino-α-dimethylaminomethyl-acrylophenon identifiziert. Durch Variation der Versuchsbedingungen konnte das Acrylophenonderivat als Hauptprodukt erhalten werden. Es war durch Saurekatalyse in 1-N-Carbathoxy-3-dimethylaminomethyl-4-oxo-1,2,3,4-tetrahydrochinolin uberfuhrbar. Synthesis of o-Acylamino-β-dimethylamino-propiophenones The aminomethylation product of o-carbethoxyamino-acetophenone, paraformaldehyde and dimethylamine-hydrochloride was identified as a mix…
Proton Acid-induced Rearrangements of α-Alkynylestradiol Methyl Ethers
1993
When subjected to proton catalysis, the α-alkynylestradiol methyl ethers 1a and 1b furnish the Rupe or Meyer-Schuster rearrangement products 2, 4, and 5a. In the presence of sulfuric acid, α-ethynylestradiol 3-methyl ether (1a) is converted into the D-homosteroid 3a. The use of deuterated acids gives rise to the formation of the corresponding deuterated steroids 2b, 2c, 3b, and 5b. Some mechanistic implications of these results are also discussed.
Über die Synthese von o-Acylamino-β-dimethylamino-propiophenonen 2. Mitt.: Aminomethylierung von o-Carbäthoxyamino- und o-Nitro-acetophenon1)
1970
Die bei der Mannich-Reaktion mit o-Carbathoxyamino- und o-Nitro-acetophenon zu Acrylophenonderivaten fuhrende Sekundarreaktion zwischen den Aminomethylierungsprodukten und Formaldehyd konnte auf folgende Weise nahezu vollstandig vermieden werden: durch Verhindern des Zerfalls von intermediar entstehendem Dimethylaminomethylol in seine Komponenten wird die Bildung des Carbonium-Imonium-Kations derart beschleunigt, das fur die Nebenreaktion erforderlicher freier Formaldehyd rasch aus dem Reaktionsmedium verschwindet. — Die Synthese von o-Carbathoxyamino-, o-Nitro- und o-Amino-β-dimethylamino-propiophenon sowie seines Formyl- und Acetylderivates wird beschrieben. Synthesis of o-Acylamino-β-dim…
Zearalenone presence in wheat field samples from Romania
2016
Comparative cytotoxicity effect of zearalenone and its metabolites on the CHO-K1 cells
2009
ChemInform Abstract: Light Induced C-C Coupling of 2-Chlorobenzazoles with Carbamates, Alcohols, and Ethers.
2016
A light induced, transition-metal-free C-C coupling reaction of 2-chlorobenzazoles with aliphatic carbamates, alcohols, and ethers is presented. Inexpensive reagents, namely sodium acetate, benzophenone, water, and acetonitrile, are employed in a simple reaction protocol using a cheap and widely available 25 W energy saving UV-A lamp at ambient temperature.
Synthesis of pyrido[2,3-d]pyrimidines in the reaction of 6-amino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone with chalcones
1992
6-Amino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone (1) reacts in boiling DMF with α,/β-unsaturated ketones 2 yielding the pyrido[2,3-d]pyrimidine systems 5 and 6, respectively. The orientation in the addition process can be determined by nmr measurements, especially by NOE difference spectroscopy. The products do not correspond to a normal Skraup or Doebner-v. Miller synthesis.
Verbindungen mit potentiell positiv inotroper Wirkung, 1. Mitt. N-Substituierte 3-Amino-2-cyclopentenone aus partiell hydrierten 2-Phenanthrylaminen
1984
Die Darstellung partiell hydrierter 2-Phenanthrylamine und ihre Umsetzung mit 1,3-Cyclopentandion zu N-subst. 3-Amino-2-cyclopentenonen wird beschrieben. Compounds with Potentially Positive Inotropic Activity, I: N-Substituted 3-Amino-2-cyclopentenones from Partially Hydrogenated 2-Phenanthrylamines The synthesis of partially hydrogenated 2-phenanthrylamines and their reactions with 1,3-cyclopentanedione to N-substituted 3-amino-2-cyclopentenones is described.
Konvergenz von Absorption und Fluoreszenz bei gekreuzt konjugierten Oligomeren aus Chalkon-Bausteinen
1999
The absorption and fluorescence spectra of two series of chalcone oligomers (1a–d) and (2a–d) are reported. Due to small or vanishing orbital coefficients (HMO calculation) within the cross-conjugated systems, the bathochromic shifts caused by the extension of the chains are modest. The effective conjugation lengths amount to 6 and 14 chalcone building blocks in the absorptions of the series 1 and 2. The convergence of the fluorescence bands is already reached in 1d and 2d with 4 and 8 enone units, respectively. Besides the uniform or alternate arrangement of the chalcone building blocks, the positions of the propoxy substituents show a considerable influence on the electronic transitions p…
A resorcinol derived calix[5]arene with C5-symmetry
1994
Abstract Condensation of 2,4-dihydroxy-3-hydroxymethyl benzophenone (4) in dioxane/H2SO4 gave the cyclic pentamer 5, a calix[5]arene with regular incorporation of the resorcinol units via their 2- and 6-positions. The structure follows from the 1H NMR and mass spectra and was further confirmed by single crystal X-ray analysis. Dynamic NMR in C2D2Cl4 gave a surprisingly high barrier of ΔG‡ = 17.3 kcal/mol for the cone-to-cone ring inversion.