Search results for "Intake"

Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake.

2006

0012-1797 (Print) Journal Article Research Support, Non-U.S. Gov't; The ability for the brain to sense peripheral fuel availability is mainly accomplished within the hypothalamus, which detects ongoing systemic nutrients and adjusts food intake and peripheral metabolism as needed. Here, we hypothesized that mitochondrial reactive oxygen species (ROS) could trigger sensing of nutrients within the hypothalamus. For this purpose, we induced acute hypertriglyceridemia in rats and examined the function of mitochondria in the hypothalamus. Hypertriglyceridemia led to a rapid increase in the mitochondrial respiration in the ventral hypothalamus together with a transient production of ROS. Cerebral…

Intuitive eating: A novel eating style? Evidence from a Spanish sample

2020

Contains fulltext : 217000.pdf (Publisher’s version ) (Closed access) Intuitive eating is defined as an adaptive way of eating that maintains a strong connection with the internal physiological signs of hunger and satiety. It has four elements: unconditional permission to eat whenever and whatever food is desired, eating for physical rather than for emotional reasons, reliance on hunger and satiety cues to determine when and how much to eat, and body-food choice congruence. In this study, we assessed the differences and similarities between intuitive eating, as measured with the Intuitive Eating Scale-2, and eating styles (restrained, emotional, and external eating), as assessed with the Du…

Target vs non-target analysis to determine pesticide residues in fruits from Saudi Arabia and influence in potential risk associated with exposure

2017

The occurrence of pesticide residues in fruits was determined by a target method for 62 analytes and a wide scope screening method against a database of 500 pesticides. Limits of quantification (LOQs) were from 0.5 to 6.3 μg kg−1 for the target method and from 0.5 to 119 μg kg−1 for the non-target. Thirty samples: dates, apples, oranges, tangerines, lemons and grapefruits were selected because their high consumption, except lemons and grapefruits that were to cover all citrus fruits. Using the target method, 15 compounds (mostly insecticides and fungicides) out of 62 pesticides (organophosphorus, carbamates, pyrethroids, chloroacetanilides, triazines, triazoles, imidazoles, etc.) were detec…

Avoin ongelmista - ongelma avoimuudesta? : arvonluonnin diskurssit integroiduissa raporteissa

2015

Tutkimuksen tavoitteena oli lisätä ymmärrystä integroidusta raportoinnista ja syventää ymmärrystä arvonluonnin käsitteestä. Työn teoreettinen viitekehys rakentui vuosikertomuksiin, yhteiskuntavastuuseen ja integroituun raportointiin liittyvästä tutkimuskirjallisuudesta. Työn aineistona käytettiin seitsemän pohjoismaisen rakennus- ja infrastruktuurialan integroitua raporttia vuosilta 2012–2013. Työn metodologisena otteena käytettiin kolmeen tasoon jaettua kriittistä diskurssianalyysiä, jossa analyysi alkaa tekstuaaliselta tasolta ja siirtyy tulkinnallisen analyysin jälkeen kriittisen analyysin tasolle. Kriittisellä tasolla tarkastellaan arvonluontiin liittyviä valtarakenteita ja niiden ongel…

Assessment of Iron Intake in Relation to Tolerable Upper Intake Levels

2018

Vuosikertomus 2012 : Informaatioteknologian tiedekunta, Jyväskylän yliopisto

2013

The case for strategic international alliances to harness nutritional genomics for public and personal health

2005

Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need …

Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on Hormones of Energy Balance in a TCDD-Sensitive and a TCDD-Resistant Rat Strain

2014

One of the hallmarks of the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a drastically reduced feed intake by an unknown mechanism. To further elucidate this wasting syndrome, we followed the effects of a single large dose (100 μg/kg) of TCDD on the serum levels of several energy balance-influencing hormones, clinical chemistry variables, and hepatic aryl hydrocarbon receptor (AHR) expression in two rat strains that differ widely in their TCDD sensitivities, for up to 10 days. TCDD affected most of the analytes in sensitive Long-Evans rats, while there were few alterations in the resistant Han/Wistar strain. However, analyses of feed-restricted unexposed Long-Evans rats i…

Leptin and the central control of feeding behavior.

2012

International audience; The discovery of leptin by Friedman and coll. in 1995 was a major step forward in our comprehensive view of energy homeostasis. Since the original paper, a tremendous amount of work has been performed in laboratories all over the world. Many recent reviews have described this work in details. In the present review, we focus on the role of leptin on food intake. It is accepted by most authors working in this field that the control of food intake can be divided in two closely-related system: the homeostatic system and the hedonic system. Leptin has been shown to act on both systems.

Chronic social stress lessens the metabolic effects induced by a high-fat diet

2021

Stress has a major impact on the modulation of metabolism, as previously evidenced by hyperglycemia following chronic social defeat (CSD) stress in mice. Although CSD-triggered metabolic dysregulation might predispose to pre-diabetic conditions, insulin sensitivity remained intact, and obesity did not develop, when animals were fed with a standard diet (SD). Here, we investigated whether a nutritional challenge, a high-fat diet (HFD), aggravates the metabolic phenotype and whether there are particularly sensitive time windows for the negative consequences of HFD exposure. Chronically stressed male mice and controls (CTRL) were kept under (i) SD-conditions, (ii) with HFD commencing post-CSD,…