Search results for "Malo"

Light-emitting thin films of glassy forming organic compounds containing 2-tert-butyl-6-methyl-4H-pyran-4-ylidene

2012

Low molecular mass organic compounds which make thin films from volatile organic solutions would be great benefit in future organic light emitting systems. Two most important advantages could be mentioned. First - the repetition of synthesis of small molecules is better than for polymers. Second - wet casting methods could be used. In this work we are presenting optical, electroluminescence and amplified spontaneous emission properties of four original glassy forming compounds containing 2-tert-butyl-6-methyl-4H-pyran-4-ylidene fragment as backbone of the molecule. They has the same N,N-dialkylamino electron donating group with incorporated bulky trityloxy ethyl groups. The difference of th…

Synthesis, optical, and thermal properties of glassy trityl group containing luminescent derivatives of 2-tert-butyl-6-methyl-4H-pyran-4-one

2012

In this work we present simple preparation of original trityl group containing glassy luminescent 6-styryl substituted derivatives of 2-(2-tert-butyl-4H-pyran-4-ylidene)malononitrile (DWK-1TB), 2-(2-tert-butyl-4H-pyran-4-ylidene)-2- ethyl-2-cyanoacetate (KWK-1TB), 2-(2-tert-butyl-4H-pyran-4-ylidene)-1H-indene-1,3(2H)-dione (ZWK-1TB) and 5-(2-tert-butyl-4H-pyran-4-ylidene)pyrimidine-2,4,6(1H,3H,5H)-trione (JWK-1TB). Their optical properties have been investigated. The absorption maxima of synthesized glasses is in region from 425 nm to 515 nm and emission maxima is from 470 nm to 625 nm in solution of dichloromethane. But absorption maxima of their solid films is from 425 nm to 500 nm and em…

Concentration-Dependent Antioxidant/Pro-Oxidant Activity of Ascorbic Acid in Chickens

2012

С vitamīns piedalās daudzos vielmaiņas procesos. Tas stiprina organisma imūnsistēmu, piedalās bioloģiskās oksidēšanās un reducēšanās procesos. Askorbīnskābe un dehidroaskorbīnskābe veido redoks sistēmu un ir saistītas ar glutationa sistēmu. Dažādu stresu ietekmē askorbīnskābes koncentrācija audos samazinās. Tādēļ barību vajag bagātināt ar šo vitamīnu. Darba mērķis bija pētīt dažādus oksidatīvā stresa biomarķierus cāļu organismā, kadmija akumulāciju orgānos, imūnsistēmas aktivitāti un nieru funkcijas izmaiņas askorbīnskābes ietekmē atkarībā no tās koncentrācijas barībā. Eksperimentos izmantojām vienu dienu vecus Lohmann Brown gailīšus, kurus sadalījām piecās analogās grupās. Cāļi saņēma komb…

G6PD Overexpression Protects Mice Against Associated Oxidative Stress and Delays the Occurrence of Frailty

2016

To assess the impact of lifelong overexpression of G6PD on reactive oxygen species (ROS)-derived damage and the prevention of frailty, we measured the levels of macromolecular oxidative damage in young and old mice and the we tested the neuromuscular fitness and the grip strength in old mice. Old G6PD-Tg male and female mice showed diminished accumulation of DNA oxidation (measured as 8-hydroxyguanosine or 8-OHdG) in liver and brain. Old females also showed reduced lipid oxidation (measured as malondialdehyde or MDA) in the liver. Old G6PD-Tg males, but not females, presented a small but significant increase in brain protein carbonylation. In accordance with these findings, liver from 2-yea…

Umsetzungen von polyacroleinen mit methylenaktiven verbindungen. Polymere acroleine, 21. Mitt.1

1962

Redoxpolymerisate des Acroleins wurden unter den Bedingungen einer KNOEVENAGEL-Kondensation mit methylenaktiven Verbindungen umgesetzt. Als Katalysatoren dienten Piperidin im essigsauren Medium oder Kaliumfluorid. Mit Malonsauredinitril, Cyanessigsaureathylester, Benzylcyanid, Phenylnitromethan und Acetessigsaureathylester entstehen losliche Polyacrolein-Derivate. Die Reaktionen mit Nitroacetonitril, Malonsaurediathylester, Nitromethan und Acetonitril fuhren zu unloslichen Umsetzungsprodukten. Die Umsetzungen wurden durch Elementaranalysen und IR-Spektren verfolgt. The reaction of redoxpolymers of acrolein with methylenactive compounds was studied under the conditions of a KNOEVENAGEL-conde…

1977

Deuteron relaxation times T1 of polystyrenes deuterated at the backbone (PS-d3) and the phenyl ring (PS-d5), respectively, have been measured in solutions of benzene and diethyl malonate as a function of concentration and temperature. We conclude that the motion of the phenyl ring is faster than that of the backbone, the difference being smallest at high temperatures around 180°C. The temperatures dependence is discussed in relation to the activation energies in polystyrene.

Fluorescent chemosensors based on cyclohexane: selective sensing of succinate and malonate versus their longer or shorter homologues

2008

The sensing properties towards aliphatic α,ω-dicarboxylates of five cyclohexane-based ligands are described. The studied ligands have been designed following the binding site-signalling unit approach and they all possess thiourea groups as recognition moieties. Ligands 1 and 3 containing naphthalene units can be used as fluorescent sensors as they form intra- or intermolecular excimers in the presence of appropriate dicarboxylates. Selective sensing of succinate and malonate versus their longer or shorter homologues has been observed.

ChemInform Abstract: Addition of Nucleophiles to Fluorinated Michael Acceptors.

2016

A series of nucleophiles, including primary and secondary amines, primary alcohols, and thiols, as well as diethyl malonate and nitromethane, were added to different fluorinated Michael acceptors including 2-fluoroalk-1-en-3-ones and 2-fluoro-1-phenylprop-2-en-1-one. The resulting β-substituted α-fluoro ketones were isolated in 34–92 % yield, depending on the substrate and the nucleophile. The best yields were obtained with secondary amines and with p-methylthiophenol.

Zentral dämpfende Wirkstoffe, 2. Mitt.1) 3-Substituierte 4-Hydroxypyrimido[1,2-a]benzimidazol-2-one

1983

Aus der Umsetzung von 2-Aminobenzimidazol (1) mit den Malonestern 2a–g gehen die 4-Hydroxypyrimido[1,2–a]benzimidazol-2-one 3a–g hervor, unter denen sich Vertreter mit zentral dampfenden, hypertensiven, fungiziden und antibakteriellen Eigenschaften finden. Centrally Dampening Drugs, II: 3-Substituted 4-Hydroxypyrimido[1,2-a]benzimidazol-2-ones The 4-hydroxypyrimido[1,2-a]benzimidazol-2-ones 3a–g obtained by reacting 2-aminobenzimidazole (1) with the malonic acid esters 2a–g exhibit centrally dampening, hypertensive, fungicidal, and antibacterial properties.

Increased susceptibility of microcytic red blood cells to in vitro oxidative stress.

1995

Oxidative damage to erythrocytes in thalassaemia has been related to generation of free radicals by an excess of denaturated alpha- or beta-globin chains, intracellular iron overload and low concentration of normal haemoglobin (HGB). Two good indicators of such oxidative damage are the high red blood cell (RBC) malonyldialdehyde (MDA) production detected following exogenous oxidant stress and the decrease of pyrimidine 5'-nucleotidase (P5N), the most sensitive enzyme to SH-group damage in vivo. Conflicting data, however, have so far accumulated in the literature concerning differences in oxidative damage between the different forms of thalassaemia and iron deficiency anaemia (IDA). In the p…