Search results for "Map"

Nucleotide sequence of plasmid p4028, a cryptic plasmid from Leuconostoc oenos.

1996

Abstract TheLeuconostoc oenosplasmid p4028 was cloned in pBlueScript (SK+), and its complete nucleotide sequence was determined. The analysis of the nucleotide sequence revealed five open reading frames, all of them located on the same strand and grouped in two clusters separated by a short noncoding stretch. A similarity search against the other sequences deposited in the EMBL and GenBank databases showed that p4028 has no significant similarity with any of the sequences checked. Nevertheless, a putative ATP-binding motif was found in ORF2. A more detailed analysis of this ORF suggests that it could encode for a DNA-dependent ATPase.

Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2.

2003

Intrachromosomal duplications play a significant role in human genome pathology and evolution. To better understand the molecular basis of evolutionary chromosome rearrangements, we performed molecular cytogenetic and sequence analyses of the breakpoint region that distinguishes human chromosome 3p12.3 and orangutan chromosome 2. FISH with region-specific BAC clones demonstrated that the breakpoint-flanking sequences are duplicated intrachromosomally on orangutan 2 and human 3q21 as well as at many pericentromeric and subtelomeric sites throughout the genomes. Breakage and rearrangement of the human 3p12.3-homologous region in the orangutan lineage were associated with a partial loss of dup…

7E olfactory receptor gene clusters and evolutionary chromosome rearrangements

2005

Olfactory receptor (OR) genes of the 7E subfamily have been duplicated to multiple regions throughout the human genome. Segmental duplications containing 7E OR genes have been associated with both pathological and evolutionary chromosome rearrangements. Many of these breakpoint regions coincide with breaks of chromosomal synteny in the mouse, rat and/or chicken genomes. Collectively, these data suggest that 7E OR-containing regions represent hot spots of genomic instability.    

Pulsed field gel electrophoresis and genome size estimates

2015

Pulsed field gel electrophoresis (PFGE) is a quick and reliable procedure to resolve DNA molecules larger than 30 kb by applying an electric field that periodically changes direction. This technique can be used to estimate genome size of a microorganism, to reveal if a genome is circular or linear, to indicate the presence of megaplasmids, and to show if a strain contains only one or more chromosomes.

Chromatin structure of the yeast SUC2 promoter in regulatory mutants

1992

We have previously suggested that two positioned nucleosomes are removed from the promoter of the Saccharomyces cerevisiae SUC2 gene upon derepression by glucose starvation. To gain further insight into the changes accompanying derepression at the chromatin level we have studied the chromatin structure of the SUC2 promoter in several mutants affecting SUC2 expression. The non-derepressible mutants snf1, snf2 and snf5 present a chromatin structure characteristic of the repressed state, irrespective of the presence or absence of glucose. The non-repressible mutants, mig1 and ssn6, as well as the double mutant snfs sn6 exhibit an opened chromatin structure even in the presence of glucose. Thes…

Genome search in celiac disease.

1998

SummaryCeliac disease (CD), a malabsorption disorder of the small intestine, results from ingestion of gluten. The HLA risk factors involved in CD are well known but do not explain the entire genetic susceptibility. To determine the localization of other genetic risk factors, a systematic screening of the genome has been undertaken. The typing information of 281 markers on 110 affected sib pairs and their parents was used to test linkage. Systematic linkage analysis was first performed on 39 pairs in which both sibs had a symptomatic form of CD. Replication of the regions of interest was then carried out on 71 pairs in which one sib had a symptomatic form and the other a silent form of CD. …

Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies.

2015

Understanding the genetic architecture of adaptive traits has been at the centre of modern evolutionary biology since Fisher; however, evaluating how the genetic architecture of ecologically important traits influences their diversification has been hampered by the scarcity of empirical data. Now, high-throughput genomics facilitates the detailed exploration of variation in the genome-to-phenotype map among closely related taxa. Here, we investigate the evolution of wing pattern diversity in Heliconius, a clade of neotropical butterflies that have undergone an adaptive radiation for wing-pattern mimicry and are influenced by distinct selection regimes. Using crosses between natural wing-pat…

Fuzzy Cognitive Maps-Based Modelling of Residential Mobility Dynamics: GeoComputation Approach

2017

International audience; This paper is concerned with proposing a fuzzy cognitive maps (FCMs) driven approach for geocomputing urban dynamics (social, spatial and temporal) as a complex system. After an overview of FCMs, mathematical fundamentals methodology that this theory suggests are examined. Then, the formalization and algorithm implementation of a model apply to residential mobility in urban space based on FCMs is described. Very good results were obtained, demonstrating that the use of these modelling approach is good and reliable.

Geochemical mapping of magmatic gas-water-rock interactions in the aquifer of Mount Etna volcano

2001

Non-equivariant cylindrical contact homology

2013

It was pointed out by Eliashberg in his ICM 2006 plenary talk that the integrable systems of rational Gromov-Witten theory very naturally appear in the rich algebraic formalism of symplectic field theory (SFT). Carefully generalizing the definition of gravitational descendants from Gromov-Witten theory to SFT, one can assign to every contact manifold a Hamiltonian system with symmetries on SFT homology and the question of its integrability arises. While we have shown how the well-known string, dilaton and divisor equations translate from Gromov-Witten theory to SFT, the next step is to show how genus-zero topological recursion translates to SFT. Compatible with the example of SFT of closed …