Search results for "PAM"

showing 10 items of 1768 documents

Hybrid chaotic firefly decision making model for Parkinson’s disease diagnosis

2020

Parkinson’s disease is found as a progressive neurodegenerative condition which affects motor circuit by the loss of up to 70% of dopaminergic neurons. Thus, diagnosing the early stages of incidence is of great importance. In this article, a novel chaos-based stochastic model is proposed by combining the characteristics of chaotic firefly algorithm with Kernel-based Naïve Bayes (KNB) algorithm for diagnosis of Parkinson’s disease at an early stage. The efficiency of the model is tested on a voice measurement dataset that is collected from “UC Irvine Machine Learning Repository.” The dynamics of chaos optimization algorithm will enhance the firefly algorithm by introducing six types of chao…

Firefly protocolParkinson's diseasekernel density estimation functionComputer Networks and CommunicationsComputer scienceDopaminergicGeneral EngineeringChaotic020206 networking & telecommunications02 engineering and technologymedicine.diseaseChaos theorylcsh:QA75.5-76.95chaotic mapscalibration measure0202 electrical engineering electronic engineering information engineeringmedicine020201 artificial intelligence & image processinglcsh:Electronic computers. Computer sciencereceiver operating characteristic curvemetaheuristic algorithmNeuroscienceInternational Journal of Distributed Sensor Networks
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Vecākā pirmsskolas vecuma bērnu pašvadītas mācīšanās prasmju attīstība fizisko aktivitāšu un veselības jomā

2022

Kvalifikācijas darba temats: Vecākā pirmsskolas vecuma bērnu pašvadītas mācīšanās prasmju attīstība fizisko aktivitāšu un veselības jomā. Darba autore: Marina Ābele Zinātniskais vadītājs: Ilvis Ābeļkalns Kvalifikācijas darbs izstrādāts ar mērķi teorētiski analizēt un praktiski aprobēt vecākā pirmsskolas vecuma bērnu pašvadītas mācīšanās veicināšanas iespējas fiziskās aktivitātes un veselības jomā. Kvalifikācijas darbs sastāv no divām daļām: •Teorētiskājā daļā apkopotas pedagogu un psihologu atziņas par pašvadītas mācīšanās prasmju attīstību fizisko aktivitāšu un veselības jomā. Teorētiskā daļa balstās uz J.Rinķa (2002); R. Fišera ( 2005); A.Vorobjova (2000); A. Šponas (2006); A. Šponas un I…

Fiziskā aktivitāteAttīstībaPirmsskolas pedagoģijaPašvadīta mācīšanāsKognitīvās spējasPamatprasmes
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Agrīnā pirmsskolas vecuma bērnu pamatkustību pilnveides veicināšana pedagoģiskajā procesā

2019

Autors: Santa Pētersone Pētījuma tēma: Agrīnā pirmsskolas vecuma bērnu pamatkustību pilnveides veicināšana pedagoģiskajā procesā. Pētījuma mērķis: teorētiski izzināt un praktiski pamatot agrīnā pirmsskolas vecuma bērnu pamatkustību pilnveides veicināšanas iespējas pedagoģiskajā procesā. Atslēgas vārdi: pamatkustības, fiziskā aktivitāte, pedagoģiskais process, pedagoģiskie paņēmieni. Informācijas iegūšanai par pētāmo objektu tika analizēta pedagoģiski un psiholoģiski zinātniskā literatūra. Izmantotas pedagogu un psihologu R. Karlovskas, A. Kuzņecovas, D.Dzinteres, R.Bošas, I.Elnebijas, I. Bulas – Bitenieces, R. Jansones un citu atziņas. Teorētiskajā daļā aplūkots: 1.Bērnu fiziskās aktivitāte…

Fiziskā aktivitātePirmsskolas pedagoģijaPedagoģiskais processPedagoģiskie paņēmieniPamatkustības
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Vecākās pirmsskolas vecuma bērnu pamatkustību apguves sekmēšana kustību rotaļās

2019

Darba nosaukums: Vecākā pirmsskolas vecuma bērnu pamatkustības apguves sekmēšana kustību rotaļās. Darba autore: Laila Tauriņa. Darba mērķis ir teorētiski analizēt un praktiski pētīt vecākā pirmsskolas vecuma bērnu pamatkustību apguves sekmēšanas iespējas kustību rotaļās. Lai sasniegtu nostādīto mērķi bērniem tika dota iespēja caur kustību rotaļām nostiprināt pamatkustības: skriešanu, lekšanu, rāpošanu, mešanu, tveršanu. Darba autore izvirzīja hipotēzi, ka pamatkustību apguves kustību rotaļās noritēs veiksmīgi, ja skolotāja regulāri izmantos kustību rotaļas, ja skolotājs ņems vērā bērnu intereses, kā arī, bērni aktīvi iesaistīsies kustību rotaļās. Darbs sastāv no divām daļām – teorētiskās un…

Fiziskā attīstībaKustību rotaļasRotaļasSkolas pedagoģijaPirmsskolēnsPamatkustības
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Benzodiazepines for catatonic symptoms, stupor, and mutism.

1988

FlumazenilPediatricsmedicine.medical_specialtyDepressive DisorderDiazepamMutismbusiness.industryStuporCatatoniaGeneral MedicineLorazepamPsychiatry and Mental healthBenzodiazepinesAnti-Anxiety AgentsmedicineHumansPharmacology (medical)Femalemedicine.symptombusinessPharmacopsychiatry
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Photoluminescent decoration of iron oxide magnetic nanoparticles for dual-imaging applications

2018

A selective functionalization of dopamine amino group with the photoluminescent 7-nitroben-zofurazan was achieved through a one-pot protection-functionalization-deprotection sequence. The resulting fluorescent catecholic ligand was used as a capping agent for iron oxide nanoparticles thus obtaining photoluminescent magnetic nanoparticles (PL-MNPs). The PL-MNPs were then embedded into PLGA-b-PEG polymeric nanocarriers which quenched the emission of the capping agent. Full recovery of fluorescence was observed after disassembling the polymeric layer of the nanoparticle, thus supporting the use of PL-MNPs as a multifunctional system for targeted drug delivery.

Fluorescent nanoparticleMaterials scienceAtomic and Molecular Physics and OpticDopamineMagnetic nanoparticleIron oxideNanoparticleNanotechnologyBioengineering02 engineering and technology010402 general chemistry01 natural scienceschemistry.chemical_compoundGeneral Materials ScienceChemistry (all)technology industry and agricultureSettore CHIM/06 - Chimica OrganicaGeneral Chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsFluorescenceAtomic and Molecular Physics and Optics0104 chemical scienceschemistryTargeted drug deliveryDual-imagingModeling and SimulationDrug deliveryDrug deliverySurface modificationMagnetic nanoparticlesMaterials Science (all)0210 nano-technologyIron oxide nanoparticles
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The DAT ligand [(18)F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [(11)C]cocaine with significantly improved monoamine transporter selecti…

2010

Fluorine RadioisotopesContrast MediaPharmacologyLigandsBiochemistryRats Sprague-DawleyPharmacokineticsCocaineIn vivoDrug DiscoverymedicineAnimalsBiogenic MonoaminesCarbon RadioisotopesGeneral Pharmacology Toxicology and PharmaceuticsDopamine transporterPharmacologyDopamine Plasma Membrane Transport ProteinsMonoamine transporterbiologymedicine.diagnostic_testChemistryOrganic ChemistryLigand (biochemistry)RatsBiochemistryPositron emission tomographyPositron-Emission Tomographybiology.proteinMolecular MedicineRadiopharmaceuticalsSelectivityChemMedChem
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Efficient microwave-assisted direct radiosynthesis of [(18)F]PR04.MZ and [(18)F]LBT999: selective dopamine transporter ligands for quantitative molec…

2009

Abstract PR04.MZ 8-(4-fluoro-but-2-ynyl)-3- p -tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester ( 1 ) and LBT999 8-(( E )-4-fluoro-but-2-enyl)-3b- p -tolyl-8-aza-bicyclo[3.2.1]octane-2β-carboxylic acid methyl ester ( 2 ) are selective dopamine reuptake inhibitors, derived from cocaine. Compounds 1 and 2 were labelled with fluorine-18 at their terminally fluorinated N-substituents employing microwave enhanced direct nucleophilic fluorination. K[ 18 F]F − Kryptofix ® 222 cryptate, tetrabutyl ammonium [ 18 F]fluoride and caesium [ 18 F]fluoride were compared as fluoride sources under conventional and microwave enhanced conditions. Fluorination yields were remarkably increased un…

Fluorine RadioisotopesStereochemistryClinical BiochemistryPharmaceutical Sciencechemistry.chemical_elementCesiumLigandsBiochemistryChemical synthesischemistry.chemical_compoundFluoridesNucleophileCocaineDrug DiscoveryMicrowavesMolecular BiologyDopamine Plasma Membrane Transport ProteinsLigandOrganic ChemistryRadiosynthesischemistryModels ChemicalCaesiumIsotope LabelingPositron-Emission TomographyMolecular MedicineRadiopharmaceuticalsSelectivityAliphatic compoundFluorideNuclear chemistryTropanesBioorganicmedicinal chemistry
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Fluência verbal fonêmica e semntica: dados normativos de idosos Brasileiros

2015

This study aims to investigate the influence of sociodemographic characteristics on the performance of older people on two tasks of verbal fluency and provide normative data for a Brazilian population of healthy elderly individuals with different educational levels. The initial sample included 521 individuals aged from 60 years, participating in the Program Family Health Strategy. Participants who had scores suggestive of cognitive decline on the Mini-Mental State Examination, depressive symptoms in Geriatric Depression Scale and self-reported neurological or psychiatric disorders were excluded. The final sample consisted of 218 participants in phonemic verbal fluency task (letters F, A and…

Fluência verballcsh:BF1-990Psicologia del desenvolupamentHealthy elderlyVerbal fluencynormative dataelderlybehavioral disciplines and activitiesTask (project management)Semànticadados normativoslcsh:PsychologyidososNormativeVerbal fluency testGeriatric Depression ScaleEducacióCognitive declinePsychologyOlder peopleDepressive symptomsClinical psychologyPsicologia: Reflexão e Crítica
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Towards a more sustainable food Supply chain: opening up invisible waste in food service

2016

Future challenges to the global food supply chain are complex. In order to embrace sustainability, companies should change their management practices towards more efficient resource use. Food waste being a misuse of resources, we identify its causes and possible ways of minimising it. To achieve this goal, we conducted explorative research with qualitative and quantitative data through in-depth semi-structured interviews and an open questionnaire with top Spanish food service companies. Results show that most businesses mainly tend to minimise food waste according to economic criteria, without taking into account the social, ethical or environmental factors. As a consequence, just “visible”…

Food industrySupply chainGeography Planning and Developmentlcsh:TJ807-830lcsh:Renewable energy sourcesFood supply010501 environmental sciencesManagement Monitoring Policy and Law01 natural sciencesfood supply chain0502 economics and business:Enginyeria agroalimentària::Indústries agroalimentàries::Alimentació i nutrició humana [Àrees temàtiques de la UPC]lcsh:Environmental sciences0105 earth and related environmental sciencesMercat Investigaciólcsh:GE1-350sustainable developmentMalbaratament d'alimentsRenewable Energy Sustainability and the Environmentbusiness.industrySeguretat alimentàrialcsh:Environmental effects of industries and plantsFood waste05 social sciencesEnvironmental resource management:Desenvolupament humà i sostenible::Desenvolupament humà [Àrees temàtiques de la UPC]Aliments -- AbastamentFood securityEnvironmental economicsFood safetysustainability; food waste; sustainable development; food supply chain; food service; food surplussustainabilityFood packagingFood wastelcsh:TD194-195food wasteSustainability:Economia i organització d'empreses::Aspectes socials [Àrees temàtiques de la UPC]Food systemsCleaner productionfood surplusbusinessfood service050203 business & management
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