Search results for "Plant Root"

showing 10 items of 232 documents

Steroidal saponins from the roots of Smilax aspera subsp. mauritanica

2008

Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG. (Liliaceae), together with the known curillin G (3), asparagoside E (4), asparoside A (5), asparoside B (6) and the phenolic compound resveratrol (7). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 3 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (minimum inhibitory concentrations of 25, 25 and 50 microg/ml, respectively) whereas the other compounds were inactive.

AntifungalSpectrometry Mass Electrospray IonizationAntifungal AgentsMagnetic Resonance SpectroscopySpectrophotometry Infraredmedicine.drug_classMolecular Sequence DataPharmaceutical ScienceMicrobial Sensitivity TestsSpectrometry Mass Fast Atom BombardmentResveratrolPlant RootsAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryBotanymedicineCandida albicansSpectral dataSmilax asperaCandidaPharmacologybiologyTraditional medicineLiliaceaeHydrolysisOrganic ChemistryFungiGeneral ChemistryGeneral MedicineSaponinsbiology.organism_classificationKetoconazoleCarbohydrate SequenceComplementary and alternative medicinechemistrySmilaxMolecular MedicineSteroidsPlanta Medica
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Antimicrobial and antiproliferative activity of Peucedanum nebrodense (Guss.) Strohl.

2003

Abstract Acetone extract of Peucedanum nebrodense (Guss.) Strohl., a rare endemic species from the Madonie mountains (Sicily), was tested in vitro for its antimicrobial activity against bacterial reference strains and antiproliferative activity against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and L1210 (murine leukemia) cell lines. The acetone extract showed antiproliferative IC 50 values in the range of 14–0.27 μg/ml.

Antineoplastic AgentsHL-60 CellsBiologyPlant RootsAcetoneMiceAnti-Infective Agentshemic and lymphatic diseasesDrug DiscoverymedicinePeucedanum nebrodenseCoumarins Antimicrobial Antiproliferative activityAnimalsHumansLeukemia L1210PharmacologyTraditional medicinePlant ExtractsBiological activityPlant Components AerialAntimicrobialmedicine.diseaseIn vitroLeukemiaCell cultureK562 CellsPeucedanum nebrodenseCell DivisionChronic myelogenous leukemiaK562 cellsApiaceaeJournal of ethnopharmacology
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Comparative analysis of radical scavenging and antioxidant activity of phenolic compounds present in everyday use spice plants by means of spectropho…

2010

Comparative analysis of radical scavenging and antioxidant activities of phenolic compounds present in everyday use spice plants was carried out by means of spectrophotometric and chromatographic methods. Six spice plant samples, namely onion (Allium cepa), parsley (Petroselinum crispum) roots and leaves, celery (Apium graveolens) roots and leaves and leaves of dill (Anethum graveolens) were analyzed. Total amount of phenolic compounds and radical scavenging activity (RSA) was the highest in celery leaves and dill extracts and was the lowest in celery roots. Comparing commonly used spectrophotometric analysis of 2,2-diphenyl-1-picrylhydrazyl (DPPH) RSA of extracts with the results obtained …

AntioxidantDPPHmedicine.medical_treatmentFiltration and SeparationPharmacognosyPlant RootsHigh-performance liquid chromatographyAntioxidantsAnalytical Chemistrychemistry.chemical_compoundPhenolsOnionsElectrochemistrymedicinePhenolsSpicesChromatography High Pressure LiquidApiumChromatographybiologyChemistryAnethum graveolensApium graveolensFree Radical Scavengersbiology.organism_classificationPlant LeavesAlliumPetroselinumAnethum graveolensJournal of Separation Science
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The symbiosis between Nicotiana tabacum and the endomycorrhizal fungus Funneliformis mosseae increases the plant glutathione level and decreases leaf…

2015

Over time, anthropogenic activities have led to severe cadmium (Cd) and arsenic (As) pollution in several environments. Plants inhabiting metal(loid)-contaminated areas should be able to sequester and detoxify these toxic elements as soon as they enter roots and leaves. We postulated here that an important role in protecting plants from excessive metal(loid) accumulation and toxicity might be played by arbuscular mycorrhizal (AM) fungi. In fact, human exploitation of plant material derived from Cd- and As-polluted environments may lead to a noxious intake of these toxic elements; in particular, a possible source of Cd and As for humans is given by cigarette and cigar smoke. We investigated …

AntioxidantPhysiologyNicotiana tabacummedicine.medical_treatmentAM fungi Arsenic Cadmium Cigarettes Glutathione Mycorrhiza Smoking Tobacco ARBUSCULAR MYCORRHIZAL FUNGI PHOSPHATE-UPTAKE SYSTEM HOLCUS-LANATUS L GLOMUS-MOSSEAE PHYTOCHELATIN SYNTHASE TRANSGENIC TOBACCO BINDING PEPTIDES L. TYPES ACCUMULATION TOLERANCEPlant SciencePlant RootsAntioxidantsARBUSCULAR MYCORRHIZAL FUNGIGlomeromycotachemistry.chemical_compoundMycorrhizaeSoil PollutantsMycorrhizaHOLCUS-LANATUS LCadmiumbiologyMedicine (all)SmokingAdaptation PhysiologicalGlutathioneAM fungi; Arsenic; Cadmium; Cigarettes; Glutathione; Mycorrhiza; Smoking; Tobacco; Adaptation; Physiological; Antioxidants; Glomeromycota; Mycorrhizae; Plant Leaves; Plant Roots; Soil Pollutants; Stress; Symbiosis; Plant Science; Genetics; Physiology; Medicine (all)AM fungiBINDING PEPTIDESCadmiumSettore BIO/07 - EcologiaGLOMUS-MOSSEAEPhysiologicalchemistry.chemical_elementPHYTOCHELATIN SYNTHASEFungusStressAM fungi; arsenic; cadmium; cigarettes; glutathione; mycorrhiza; smoking; tobaccoArsenicSymbiosisStress PhysiologicalBotanyTobaccomedicineGeneticsTOLERANCEAdaptationGlomeromycotaSymbiosisACCUMULATIONCigarettesfungiL. TYPESGlutathionebiology.organism_classificationPHOSPHATE-UPTAKE SYSTEMTRANSGENIC TOBACCOPlant LeaveschemistryMycorrhiza
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Delivery of liquorice extract by liposomes and hyalurosomes to protect the skin against oxidative stress injuries.

2015

Liquorice extract, obtained by percolation in ethanol of Glycyrrhiza glabra L. roots, was incorporated in liposomes and hyalurosomes, new phospholipid-sodium hyaluronate vesicles, and their protective effect against oxidative stress skin damages was probed. As a comparison, raw glycyrrhizin was also tested. All the vesicles were small in size (≤ 100 nm), with a highly negative zeta potential ensuring long-term stability, and able to incorporate a high amount of the extract. In vitro tests showed that the liquorice extract loaded in vesicles was able to scavenge DPPH free radical (80% inhibition) and to protect 3T3 fibroblasts against H2O2-induced oxidative stress, restoring the normal condi…

AntioxidantPolymers and PlasticsDPPHmedicine.medical_treatmentAdministration TopicalChemistry PharmaceuticalPharmacologymedicine.disease_causePlant Rootschemistry.chemical_compoundMiceDrug StabilityIn vivoCell MovementMaterials TestingMaterials ChemistrymedicineGlycyrrhizaAnimalsEdemaHyaluronic AcidGlycyrrhizinCell ProliferationSkinLiposomeDrug CarriersbiologyPlant ExtractsOrganic Chemistry3T3 CellsFree Radical Scavengersbiology.organism_classificationOxidative StresschemistryBiochemistryLiposomesGlycyrrhizaFemaleDrug carrierOxidative stressCarbohydrate polymers
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Ultrasonically-Assisted and Conventional Extraction from Erodium Glaucophyllum Roots Using Ethanol:Water Mixtures: Phenolic Characterization, Antioxi…

2020

The paper presents experimental results concerning the ultrasonically-assisted extraction of bioactive compounds from Erodium glaucophyllum roots. A comparison with conventional methodology is presented, and thereby the phytochemical composition and the antioxidant and anti-inflammatory activities of extracts are evaluated. The phenolic profile of Erodium extracts was analyzed by TOF&ndash

Antioxidantantioxidantmedicine.medical_treatmentAnti-Inflammatory AgentsPharmaceutical Science02 engineering and technologyPlant RootsAntioxidantsAnalytical Chemistrychemistry.chemical_compoundDrug DiscoverySolid phase extractionCarotenoidChromatography High Pressure Liquidanti-inflammatorychemistry.chemical_classificationbiologyChemistryultrasound04 agricultural and veterinary sciences021001 nanoscience & nanotechnology040401 food scienceUltrasonic WavesChemistry (miscellaneous)Molecular MedicineAntioxidant0210 nano-technologysolid-liquid extractionErodiumPolyphenolTECNOLOGIA DE ALIMENTOSmedicine.drug_classAnti-inflammatoryArticlelcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryPhenolsUltrasoundmedicinePhysical and Theoretical ChemistryChromatographyEthanolPlant ExtractsOrganic ChemistryExtraction (chemistry)Solid-liquid extractionbiology.organism_classificationpolyphenolTracheophytaPolyphenolSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationTroloxAnti-inflammatoryChromatography LiquidMolecules
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New pregnane and phenolic glycosides from Solenostemma argel.

2016

Abstract From the aerial parts, pericarps and roots of Solenostemma argel, three new pregnane glycosides (1–3) with two known ones and a new phenolic glycoside (4) have been isolated. Their structures were established by extensive 1D – and 2D NMR and mass spectroscopic analysis. The cytotoxicity of all compounds was evaluated against two human tumor cell lines (SW 480, MCF-7), but none of them was active in the concentration range 0.9–59.0 μM. Compounds 2 and the known argeloside F at non toxic concentrations for the PBMCs (27.3 μM and 27.6 μM, respectively) significantly decreased the Il-1β production by LPS-stimulated PBMCs. All isolated compounds showed a significant antioxidant potentia…

Antioxidantmedicine.drug_classmedicine.medical_treatmentAnti-Inflammatory Agents01 natural sciencesPlant RootsAnti-inflammatorychemistry.chemical_compoundPhenolsCell Line TumorDrug DiscoverymedicineOrganic chemistryHumansGlycosidesCytotoxicityPharmacologychemistry.chemical_classificationChromatographyApocynaceaebiologyMolecular Structure010405 organic chemistryPlant ExtractsPregnaneGlycosideGeneral Medicinebiology.organism_classificationPregnanesAntineoplastic Agents Phytogenic0104 chemical sciencesApocynaceae010404 medicinal & biomolecular chemistrychemistryLeukocytes MononuclearTroloxTwo-dimensional nuclear magnetic resonance spectroscopyFitoterapia
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In vitro digestion of betalainic foods. Stability and bioaccessibility of betaxanthins and betacyanins and antioxidative potential of food digesta.

2008

Betalains are considered to be bioactive dietary phytochemicals. The stability of betacyanins and betaxanthins from either fresh foods or manufactured products of cactus pear fruit ( Opuntia ficus indica L. Mill. cv. Gialla and Rossa) and red beet ( Beta vulgaris L. ssp. vulgaris) was assessed in a simulated oral, gastric, and small intestinal digestion and compared with the digestive stability of purified pigments. A minor loss of indicaxanthin, at the gastric-like environment only, and a decrease of vulgaxanthin I through all digestion steps were observed, which was not affected by food matrix. In contrast, food matrix prevented decay of betanin and isobetanin at the gastric-like environm…

Antioxidantmedicine.medical_treatmentBetalainsBiological AvailabilityBiologyIn Vitro TechniquesBetaxanthinsPlant RootsAntioxidantschemistry.chemical_compoundPigmentDrug StabilityBetalainSettore BIO/10 - Biochimicasimulated digestionmedicineBetacyaninsFood scienceBetaninbetaxanthindigestive oral and skin physiologyOpuntiaGeneral ChemistryBetaxanthinsBetalainic foodchemistryFoodvisual_artFruitvisual_art.visual_art_mediumDigestionBetacyaninsBeta vulgarisGeneral Agricultural and Biological SciencesDigestionIndicaxanthinJournal of agricultural and food chemistry
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Flavonoids from Erythrina schliebenii

2017

Prenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2–4), and nineteen known natural products (5–23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32–64 μg mL–1 and 36.9–101.8 μM, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0–290.6 μM (pure compounds) and 38.3 to >100 μg mL–1 (crude extracts).

Antitubercular AgentsPharmaceutical ScienceMicrobial Sensitivity TestsPlant RootsTanzania01 natural sciencesErythrina schliebeniiAnalytical ChemistryMycobacterium tuberculosischemistry.chemical_compoundDrug DiscoveryBotanyHumansta116Nuclear Magnetic Resonance BiomolecularErythrinaEC50FlavonoidsPharmacologyStem barkMolecular StructureTraditional medicinebiology010405 organic chemistryOrganic ChemistryErythrina schliebeniiPterocarpanMycobacterium tuberculosisIsoflavonesbiology.organism_classification0104 chemical sciences3. Good health010404 medicinal & biomolecular chemistryComplementary and alternative medicinechemistryToxicityPlant BarkMolecular MedicineDrug Screening Assays AntitumorCancer cell linesJournal of Natural Products
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Clathrin-mediated constitutive endocytosis of PIN auxin efflux carriers in Arabidopsis.

2007

SummaryEndocytosis is an essential process by which eukaryotic cells internalize exogenous material or regulate signaling at the cell surface [1]. Different endocytic pathways are well established in yeast and animals; prominent among them is clathrin-dependent endocytosis [2, 3]. In plants, endocytosis is poorly defined, and no molecular mechanism for cargo internalization has been demonstrated so far [4, 5], although the internalization of receptor-ligand complexes at the plant plasma membrane has recently been shown [6]. Here we demonstrate by means of a green-to-red photoconvertible fluorescent reporter, EosFP [7], the constitutive endocytosis of PIN auxin efflux carriers [8] and their …

Auxin effluxmedia_common.quotation_subjectRecombinant Fusion ProteinseducationEndocytic cycleArabidopsisBiologyEndocytosisClathrinPlant RootsGeneral Biochemistry Genetics and Molecular BiologyExocytosisGenes ReporterPIN proteinsInternalizationmedia_commonAgricultural and Biological Sciences(all)Indoleacetic AcidsBiochemistry Genetics and Molecular Biology(all)Arabidopsis ProteinsProtoplastsCell MembraneClathrin-Coated VesiclesReceptor-mediated endocytosisClathrinEndocytosisCell biologyLuminescent Proteinsbiology.proteinCELLBIOGeneral Agricultural and Biological SciencesCurrent biology : CB
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