Search results for "Proton"

showing 10 items of 5886 documents

3'-Arylazido-beta-alanyl-2-azido ATP, a cross-linking photoaffinity label for F1ATPases.

1989

Abstract The synthesis of the 3′-arylazido-2-azido ATP derivative 3′-O-{3-[N-(4-azido-2-nitrophenyl)-amino]propionyl}2-azido-adenosine 5′-triphosphate (2,3′-DiN3ATP) is described. The bifunc­ tional photoreactive ATP analog is characterized spectroscopically. Photoaffinity labeling of F, ATPase from Micrococcus luteus by this analog results in the inactivation of the enzyme and in the formation of higher molecular weight cross-links,

chemistry.chemical_classificationAzidesPhotoaffinity labelingbiologyLightStereochemistryAffinity Labelsbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologyMicrococcuschemistry.chemical_compoundKineticsProton-Translocating ATPasesEnzymeAdenosine TriphosphatechemistryIndicators and ReagentsBifunctionalBeta (finance)Micrococcus luteusDerivative (chemistry)Zeitschrift fur Naturforschung. C, Journal of biosciences
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Increased Acid Dissociation at the Quartz/Water Interface.

2018

As shown by a quite significant amount of literature, acids at the water surface tend to be “less” acid, meaning that their associated form is favored over the conjugated base. What happens at the solid/liquid interface? In the case of the silica/water interface, we show how the acidity of adsorbed molecules can instead increase. Using a free energy perturbation approach in combination with electronic structure-based molecular dynamics simulations, we show how the acidity of pyruvic acid at the quartz/water interface is increased by almost two units. Such increased acidity is the result of the specific microsolvation at the interface and, in particular, of the stabilization of the deprotona…

chemistry.chemical_classificationBase (chemistry)Chemistry02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesAcid dissociation constant0104 chemical sciencesFree energy perturbationMolecular dynamicsAdsorptionDeprotonationChemical engineeringMoleculeGeneral Materials SciencePhysical and Theoretical Chemistry0210 nano-technologyQuartzThe journal of physical chemistry letters
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Fine tuning of the catalytic effect of a metal-free porphyrin on the homogeneous oxygen reduction.

2011

The catalytic effect of tetraphenylporphyrin on the oxygen reduction with ferrocene in 1,2-dichloroethane can be finely tuned by varying the molar ratio of the acid to the catalyst present in the solution. The mechanism involves binding of molecular oxygen to the protonated free porphyrin base, in competition with ion pairing between the protonated base and the acid anion present.

chemistry.chemical_classificationBase (chemistry)Inorganic chemistryMetals and AlloysProtonationGeneral ChemistryPhotochemistryPorphyrinCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCatalysischemistry.chemical_compoundElectron transferchemistryFerroceneTetraphenylporphyrinMaterials ChemistryCeramics and CompositesPerchloric acidChemical communications (Cambridge, England)
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Deprotonation of Fluoro Aromatics Using Lithium Magnesates.

2004

Abstract 3-Fluoropyridine was deprotonated on treatment with 1/3 equiv of Bu 3 MgLi in THF at −10 °C. The lithium arylmagnesate formed was either trapped with electrophiles or involved in a palladium-catalyzed cross-coupling reaction with 2-bromopyridine. The use of a less nucleophilic lithium-magnesium-dialkylamide, (TMP) 3 MgLi, allowed the reaction of 3-fluoroquinoline, giving the 2,2′-dimeric derivative. 2-Fluoropyridine and 2,6-difluoropyridine were deprotonated using 1/3 equiv of the highly coordinated magnesate Bu 4 MgLi 2 in THF at −10 °C in the presence of a substoichiometric amount of 2,2,6,6-tetramethylpiperidine. 1,3-Difluorobenzene reacted similarly when treated with Bu 3 MgLi;…

chemistry.chemical_classificationBase (chemistry)Organic Chemistrychemistry.chemical_elementGeneral MedicineBiochemistryMedicinal chemistrychemistry.chemical_compoundDeprotonationchemistryNucleophileDrug DiscoveryElectrophileFluorineOrganic chemistryReactivity (chemistry)LithiumDerivative (chemistry)ChemInform
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Group 13 complexes of dipyridylmethane, a forgotten ligand in coordination chemistry.

2015

The reactions of dipyridylmethane (dpma) with group 13 trichlorides were investigated in 1 : 1 and 1 : 2 molar ratios using NMR spectroscopy and X-ray crystallography. With 1 : 1 stoichiometry and Et2O as solvent, reactions employing AlCl3 or GaCl3 gave mixtures of products with the salt [(dpma)2MCl2](+)[MCl4](-) (M = Al, Ga) as the main species. The corresponding reactions in 1 : 2 molar ratio gave similar mixtures but with [(dpma)MCl2](+)[MCl4](-) as the primary product. Pure salts [(dpma)AlCl2](+)[Cl](-) and [(dpma)AlCl2](+)[AlCl4](-) could be obtained by performing the reactions in CH3CN. In the case of InCl3, a neutral monoadduct (dpma)InCl3 formed regardless of the stoichiometry emplo…

chemistry.chemical_classificationBoron groupChemistryLigandStereochemistryligandsdipyridylmethaneMethylene bridgeNuclear magnetic resonance spectroscopyliganditMedicinal chemistrydipyridyylimetaaniCoordination complexInorganic ChemistryBipyridinechemistry.chemical_compoundkoordinaatiokemiaDeprotonationcoordination chemistryReactivity (chemistry)ta116Dalton transactions (Cambridge, England : 2003)
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Solid–liquid extraction of ω-amino acids using ditopic receptors

2008

Abstract Five heteroditopic ligands have been prepared to be used in solid–liquid extraction of ω-amino acids into DMSO solutions. The prepared ligands contain crown ethers as cation binding sites and thiourea or amide groups for anion recognition. The aliphatic zone of the 1H NMR spectra suggests that two different species related to the amino acid are present in solution. One of these species is the complexed zwitterionic form and the other seems to be free non-zwitterionic amino acid. The presence of these two species allows extraction efficiencies higher than 100%.

chemistry.chemical_classificationCation bindingChemistryOrganic ChemistryExtraction (chemistry)BiochemistryIonAmino acidchemistry.chemical_compoundThioureaAmideDrug DiscoveryPolymer chemistryProton NMROrganic chemistrySolid phase extractionTetrahedron
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Degradation of Acetylenic Triacylglyceroles and the Inactivation of Membrane Preparations from Moss Protonema Cells

1997

Protonema cells of the moss Ceratodon purpureus accumulate triacylglycerols with two acetylenic fatty acids, 9,12-octadecadien-6-ynoic acid (18:2A) and 9,12,15-octadeca-trein-6-ynoic acid (18:3A), as main components. By following the incorporation of the [14C]-precursors acetate, linoleate, α-linolenate, γ-linolenate, stearidonate and 18:2A, into 18:3A in triacylglycerol accumulating cells, the pathway for acetylenic acids could be established. 18:2A and 18:3A could be synthesized by a second desaturation of the Δ6 double bond of γ-linolenate and stearidonate, respectively. However the major pathway for 18:3A synthesis was via a Δ15 desaturation of 18:2A. Since 18:2A was found exclusively i…

chemistry.chemical_classificationCeratodon purpureusbiologyDouble bondRicinoleic acidCellSubstrate (chemistry)biology.organism_classificationIn vitrochemistry.chemical_compoundmedicine.anatomical_structureMembranechemistryBiochemistryBotanymedicineProtonema
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Chemical speciation of organic matter in natural waters. Interaction of nucleotide 5′ mono-, di- and triphosphates with major components of seawater

2004

AbstractThe interactions of nucleotide 5’ mono-, di- and triphosphates in a multicomponent ionic medium simulating the macro-composition of seawater (Na+, K+, Ca2+, Mg2+, Cl-, SO42-, Synthetic Sea Water, SSW) have been investigated at different ionic strengths and at T= 25°C. A chemical speciation model, according to which all the internal interactions between the components of the ionic medium are taken into account, was applied to determine the effective formation constants of species in the nucleotide-seawater system. The results were compared to protonation parameters calculated from single electrolyte systems. A simpler model (SSW considered as a single salt BA, with Bz+ and Az-), repr…

chemistry.chemical_classificationChemical Health and SafetyHealth Toxicology and MutagenesisInorganic chemistrySalt (chemistry)Ionic bondingProtonationElectrolytenucleotideToxicologyorganic natural matterIonspeciationchemistryStability constants of complexesspeciation; nucleotide; seawater; organic natural matterQualitative inorganic analysisSeawaterChemical speciation of organic matter. Complex formation. Natural waters. Nucleotidesseawater
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Equilibrium studies in natural fluids: interactions of -PO43−, -P2O74−and -P3O105−with the major constituents of sea water

1998

AbstractThe interaction of PiO(i+2)−(3i+1) (i = 1,2,3) with the major components of seawater has been studied potentiometrically, at 25°C, in an artificial seawater (Na+, K, Ca2+, Mg2+, Cl− and SO42−) at different salinities (5—45%o). Apparent protonation constants have been calculated, from potentiometric data, and estimated, using an appropriate complex formation model. Formation constants of complexes formed by phosphates and the cation of seawater (the inorganic content of seawater being considered as a single 1:1 salt) have been determined. The comparison between experimental and estimated results showed that a suitable complexation model can be used with a fairly good accuracy in pred…

chemistry.chemical_classificationChemical Health and SafetychemistryStability constants of complexesHealth Toxicology and MutagenesisInorganic chemistryComplex formationPotentiometric titrationArtificial seawaterSalt (chemistry)SeawaterProtonationToxicologyChemical Speciation & Bioavailability
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Direct observation and thermal transformations of dications derived from dibenzotropylium ions

1992

Abstract Carboxylic acid 1 and its derivatives 2 , 3 treated with triflic acid below −20°C afford the dications 1H 2+2- 3H 2+2. Cyclodehydration above 20°C (or in the gas-phase, CIMS of 3 ) leads to the diprotonated ketone 4H 2+2.

chemistry.chemical_classificationChemical ionizationKetoneCarboxylic acidOrganic ChemistryProtonationMass spectrometryBiochemistryIonchemistry.chemical_compoundPolycyclic compoundchemistryComputational chemistryDrug DiscoveryOrganic chemistryTriflic acidTetrahedron
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