Search results for "Renin"

Evaluering av treningstilbudet i regi av "Aktivitet på resept" i Kristiansand og Vennesla kommune Hvilken effekt har dette tilbudet på deltekernes he…

2006

Masteroppgave i idrettsvitenskap, Høgskolen i Agder Kristiansand Bakgrunn: Det totale aktivitetsnivået går nedover (Hjort et al., 1996), og en slik nedgang har konsekvenser for folks helse (Anderssen, 2000). På bakgrunn av dette har fylkesplanen for Vest-Agder programområdet ”fysisk aktivitet” som et av sju satsingsområder for folkehelsearbeidet i fylket. Dette har resultert i at prosjektet ”Aktivitet på resept” som har til hensikt å bruke økt fysisk aktivitet som virkemiddel i primær-, sekundær og tertiærforebyggende tiltak for pasientgrupper hvor fysisk aktivitet har effekt. Hensikt: Hensikten med studien er å se på den effekten ”Aktivitet på resept” har på deltakernes helserelaterte form…

Ipertensione arteriosa, sistema renina-angiotensina e ruolo terapeutico di olmesartan.

2011

A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase

2018

Scientific reports 8(1), 13104 (2018). doi:10.1038/s41598-018-31259-y

Irbesartan results in more complete blockade of human renal at1-receptor mediated effects than does candesartan cilexetil as evidenced by higher plas…

2000

Unsteady physiology and perception during long “steady state” runs. What role do training characteristics play?

2021

Master's thesis in Sports science (ME517) PURPOSE: To contribute to a better understanding of low-intensity (<LT1) endurance training by quantifying and explaining the physiological mechanisms associated with cardiac drift and fatigue during low-intensity running and relate them to training characteristics. […] RESULTS: There was a significant drift for heart rate, oxygen consumption, ventilation, RER and RPE during both runs (P<0.05). There was no difference in drift between groups for any measurements, except for running economy during LR100. The drift was similar during LR90 and LR100 for all measurements except RER, which was significantly greater during LR90 (P<0.05). CONCLUSION: The p…

Nevromuskulær trening i jentefotballen

2021

Master's thesis in Sports science (ME517) Background: It ́s claimed that physical activity and motor competence are essential components of an active lifestyle and performance in multicomponent sports such as soccer. As a functional and holistic training method, neuromuscular training may promote health-and performance related components in kids’ sports. Aim: The aim was to investigate the effects of nine weeks neuromuscular training on gross-and sports specific motor competence, strength and change of direction in girls. […] Conclusion: The neuromuscular trainings program used in this study did not show an effect on gross-and sports specific motor competence, strength or change of directio…

Two new sesquiterpene derivatives from the Tunisian endemic Ferula tunetana Pom.

2010

A new sesquiterpene ester, tunetanin A (1), a new sesquiterpene coumarin, tunetacoumarin A (2), together with eight known compounds, i.e., coladin (3), coladonin (4), isosmarcandin (5), 13-hydroxyfeselol (6), umbelliprenin (7) propiophenone (8), beta-sitosterol (9), and stigmasterol (10), were isolated from the roots of Ferula tunetana. Their structures were elucidated on the basis of extensive spectroscopic methods, including 1D- and 2D-NMR experiments and MS analysis, as well as by comparison with published data. The cytotoxicity of compounds 1-7 towards two human colon cancer cell lines, HT-29 and HCT 116, was evaluated. Compounds 3, 4, and 6 showed weak cytotoxic activities.

Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis

2016

International audience; Converging sources of evidence point to a role for inflammation in the development of depression, fatigue and cognitive dysfunction. More precisely, the tryptophan (TRP) catabolism is thought to play a major role in inflammation-induced depression. Mastocytosis is a rare disease in which chronic symptoms, including depression, are related to mast cell accumulation and activation. Our objectives were to study the correlations between neuropsychiatric features and the TRP catabolism pathway in mastocytosis in order to demonstrate mast cells' potential involvement in inflammation-induced depression. Fifty-four patients with mastocytosis and a mean age of 50.1 years were…

Increases in Plasma Tryptophan Are Inversely Associated with Incident Cardiovascular Disease in the Prevención con Dieta Mediterránea (PREDIMED) Stud…

2017

Background: During development of cardiovascular disease (CVD), interferon-γ-mediated inflammation accelerates degradation of tryptophan into downstream metabolites. A Mediterranean diet (MedDiet) consisting of a high intake of extra-virgin olive oil (EVOO), nuts, fruits, vegetables, and cereals has been demonstrated to lower the risk of CVD. The longitudinal relation between tryptophan and its downstream metabolites and CVD in the context of a MedDiet is unstudied.Objective: We sought to investigate the relation between metabolites in the tryptophan-kynurenine pathway and CVD in the context of a MedDiet pattern.Methods: We used a case-cohort design nested in the Prevención con Dieta Medite…

Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case–Cohort Study

2018

Abstract BACKGROUND Metabolites of the tryptophan–kynurenine pathway (i.e., tryptophan, kynurenine, kynurenic acid, quinolinic acid, 3-hydroxyanthranilic) may be associated with diabetes development. Using a case–cohort design nested in the Prevención con Dieta Mediterránea (PREDIMED) study, we studied the associations of baseline and 1-year changes of these metabolites with incident type 2 diabetes (T2D). METHODS Plasma metabolite concentrations were quantified via LC-MS for n = 641 in a randomly selected subcohort and 251 incident cases diagnosed during 3.8 years of median follow-up. Weighted Cox models adjusted for age, sex, body mass index, and other T2D risk factors were used. RESULTS …