Search results for "STED"

Decisioni sul termine della vita e donazione degli organi. Spunti comparatistici per una futura disciplina

2021

The essay focuses on organ donation as a possible choice for those patients seeking euthanasia or assisted suicide whose informed and free consent has to be carefully preserved. In that case, indeed, concern for the welfare of others, on the one hand, and dying for having relief from illness, on the other hand, could confusedly converge in the will of a vulnerable person receiving medical treatments. The Dutch and the Belgian statutory frameworks governing organ donation after euthanasia can shed light on this such ethical theme involving human dignity that should be ignored by the Italian legislator anymore.

Space-Frequency Quantization for Image Compression With Directionlets

2007

The standard separable 2-D wavelet transform (WT) has recently achieved a great success in image processing because it provides a sparse representation of smooth images. However, it fails to efficiently capture 1-D discontinuities, like edges or contours. These features, being elongated and characterized by geometrical regularity along different directions, intersect and generate many large magnitude wavelet coefficients. Since contours are very important elements in the visual perception of images, to provide a good visual quality of compressed images, it is fundamental to preserve good reconstruction of these directional features. In our previous work, we proposed a construction of critic…

Accuracy of Computer-Aided Dynamic Navigation Compared to Computer-Aided Static Navigation for Dental Implant Placement: An In Vitro Study

2019

Aim: To analyze the accuracy capability of two computer-aided navigation procedures for dental implant placement. Materials and Methods: A total of 40 dental implants were selected, which were randomly distributed into two study groups, namely, group A, consisting of those implants that were placed using a computer-aided static navigation system (n = 20) (guided implant (GI)) and group B, consisting of those implants that were placed using a computer-aided dynamic navigation system (n = 20) (navigation implant (NI)). The placement of the implants from group A was performed using surgical templates that were designed using 3D implant-planning software based on preoperative cone-beam computed…

Immuno-MALDI-MS in Human Plasma and on-Chip Biomarker Characterizations at the Femtomole Level

2012

Immuno-SPR-MS is the combination of immuno-sensors in biochip format with mass spectrometry. This association of instrumentation allows the detection and the quantification of proteins of interest by SPR and their molecular characterization by additional MS analysis. However, two major bottlenecks must be overcome for a wide diffusion of the SPR-MS analytical platform: (i) To warrant all the potentialities of MS, an enzymatic digestion step must be developed taking into account the spot formats on the biochip and (ii) the biological relevancy of such an analytical solution requires that biosensing must be performed in complex media. In this study, we developed a procedure for the detection …

Acidic Co-Catalysts in Cationic Gold Catalysis.

2016

A systematic study on the effects of Lewis or Bronsted acid co-catalysts in gold-catalyzed reactions was undertaken using representative reactions (O-, N-, and C-nucleophilic additions to alkynes). Through these reactions, it was demonstrated that an acidic co-catalyst can increase the catalyst turnover significantly, enabling practical reaction rates at competitive catalyst loadings (<1 mol %). Further investigation is currently underway to improve the understanding of the subtle principles underlying these experimental observations.

Combined TL and 10B-alanine ESR dosimetry for BNCT

2004

The dosimetric technique described in this paper is based on electron spin resonance (ESR) detectors using an alanine-boric compound acid enriched with 1 0 B, and beryllium oxide thermoluminescent (TL) detectors; with this combined dosimetry, it is possible to discriminate the doses due to thermal neutrons and gamma radiation in a mixed field. Irradiations were carried out inside the thermal column of a TRIGA MARK II water-pool-type research nuclear reactor, also used for Boron Neutron Capture therapy (BNCT) applications, with thermal neutron fluence from 10 9 to 10 1 4 n t h cm - 2 . The ESR dosemeters using the alanine-boron compound indicated ESR signals about 30-fold stronger than those…

Dose calculation in biological samples in a mixed neutron-gamma field at the TRIGA reactor of the University of Mainz

2010

To establish Boron Neutron Capture Therapy (BNCT) for non-resectable liver metastases and for in vitro experiments at the TRIGA Mark II reactor at the University of Mainz, Germany, it is necessary to have a reliable dose monitoring system. The in vitro experiments are used to determine the relative biological effectiveness (RBE) of liver and cancer cells in our mixed neutron and gamma fi eld. We work with alanine detectors in combination with Monte Carlo simulations, where we can measure and characterize the dose. To verify our calculations we perform neutron fl ux measurements using gold foil activation and pin-diodes . Material and methods . When L- α -alanine is irradiated with ionizing …

IP 3 signalling regulates exogenous RNA i in C aenorhabditis elegans

2015

RNA interference (RNAi) is a widespread and widely exploited phenomenon. Here, we show that changing inositol 1,4,5-trisphosphate (IP3) signalling alters RNAi sensitivity in Caenorhabditis elegans. Reducing IP3 signalling enhances sensitivity to RNAi in a broad range of genes and tissues. Conversely up-regulating IP3 signalling decreases sensitivity. Tissue-specific rescue experiments suggest IP3 functions in the intestine. We also exploit IP3 signalling mutants to further enhance the sensitivity of RNAi hypersensitive strains. These results demonstrate that conserved cell signalling pathways can modify RNAi responses, implying that RNAi responses may be influenced by an animal's physiology…

Applications of Virtualization in Systems Design

2012

Perché abbiamo un diritto costituzionalmente garantito all'eutanasia e al suicidio assistito

2019

in this article, I will argue that the italian constitution establish that sick people have a constitutional right to euthanasia and assisted suicide