Search results for "linalool"

showing 10 items of 54 documents

Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system

2018

Citrus lumia Risso Essential oil Antioxidant properties Anti-cholinesterase activity Cytotoxicity Neuroactive effects 1. Introduction Plants that produce essential oils (EOs) represent a large part of natural flora and an important resource in various fields such as pharmaceutical, food and cosmetic industries, due to their flavor, fra- grance and biological activity (Swamy et al., 2016). EOs play a pivotal role in the growth and colonization of plants, giving color and scent to reproductive organs, attracting pollinators, favoring seed dispersion (Sharifi-Rad et al., 2017), and defending the plant against abiotic (light, temperature, etc.) and biotics (herbivores, harmful insects and pa- t…

Central Nervous System0106 biological sciences0301 basic medicineCitrusAntioxidantCytotoxicitymedicine.medical_treatmentToxicology01 natural sciencesAntioxidantsEssential oillaw.inventionTerpeneMicechemistry.chemical_compoundLinaloollawSettore BIO/15 - Biologia FarmaceuticaFood scienceCitrus lumia Risso Essential oil Antioxidant properties Anti-cholinesterase activity Cytotoxicity Neuroactive effectsbiologyGeneral MedicineNeuroprotective AgentsPhytochemicalNeuroactive effectsAnti-cholinesterase activityAcyclic MonoterpenesAntioxidant propertiesNeuroprotectionGas Chromatography-Mass SpectrometryCell Line03 medical and health sciencesCyclohexenesOils VolatilemedicineAnimalsRats WistarIC50Essential oilCholinesteraseCell-Free SystemTerpenesAnti-cholinesterase activity; Antioxidant properties; Citrus lumia Risso; Cytotoxicity; Essential oil; Neuroactive effects; Food Science; Toxicology030104 developmental biologychemistryMicroscopy Electron ScanningMonoterpenesbiology.proteinCitrus lumia RissoCholinesterase InhibitorsLimonene010606 plant biology & botanyFood ScienceFood and Chemical Toxicology
researchProduct

Lavandula angustifolia Essential Oil and Linalool Counteract Social Aversion Induced by Social Defeat

2018

Many vegetable extracts, essential oils, and their main constituents are active on the Central Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers for their activity in treating CNS disorders. In this research, we studied the possible activities of Lavandula angustifolia (LA) essential oil and of its main constituent, linalool, as anti-stress compounds on anxiety and social interaction and their in vitro effects on proteins (pERK and PKA) involved in the transmission of the signal. An acute intraperitoneal injection of linalool (100 mg/kg) and of LA essential oil (200 mg/kg) reduced motor activity without any anxiolytic effect, but significantly incr…

Central Nervous System30030301 basic medicinelinaloolLavandulaVolatilePharmaceutical SciencePharmacologyAnalytical Chemistrylaw.inventionSocial defeatMicechemistry.chemical_compound0302 clinical medicineAnti-Anxiety AgentsLinaloolCentral Nervous System Diseasessocial defeatlawDrug DiscoveryHypnotics and SedativesEssential oil; Lavandula angustifolia; Linalool; Social defeat; Animals; Anti-Anxiety Agents; Antidepressive Agents; Central Nervous System; Central Nervous System Diseases; Humans; Hypnotics and Sedatives; Interpersonal Relations; Lavandula; Mice; Monoterpenes; Oils Volatile; Analytical Chemistry; Chemistry (miscellaneous); Molecular Medicine; 3003; Drug Discovery3003 Pharmaceutical Science; Physical and Theoretical Chemistry; Organic ChemistryLavandula angustifolia<i>Lavandula angustifolia</i>Antidepressive AgentsLavandulaChemistry (miscellaneous)Molecular MedicineAntidepressantmedicine.drug_classAnxiolyticArticleessential oillcsh:QD241-44103 medical and health scienceslcsh:Organic chemistrymedicineAnimalsHumansInterpersonal RelationsPhysical and Theoretical ChemistryEssential oilbusiness.industryDrug Discovery3003 Pharmaceutical ScienceOrganic Chemistry030104 developmental biologyAnti-Anxiety AgentschemistryLavandula angustifoliaMonoterpenesbusinessOils030217 neurology & neurosurgeryMolecules
researchProduct

Understanding retention and metabolization of aroma compounds using an in vitro model of oral mucosa.

2020

International audience; The mechanism leading to aroma persistence during eating is not fully described. This study aims at better understanding the role of the oral mucosa in this phenomenon. Release of 14 volatile compounds from different chemical classes was studied after exposure to in vitro models of oral mucosa, at equilibrium by Gas-Chromatography-Flame Ionization Detection (GC-FID) and in dynamic conditions by Proton Transfer Reaction- Mass Spectrometry (PTR-MS). Measurements at equilibrium showed that mucosal hydration reduced the release of only two compounds, pentan-2-one and linalool (p < 0.05), and suggested that cells could metabolize aroma compounds from different chemical fa…

Chemical structureTR146/MUC1 cellsAcyclic MonoterpenesKinetics01 natural sciencesGas Chromatography-Mass SpectrometryAnalytical Chemistrychemistry.chemical_compoundEating0404 agricultural biotechnologyLinaloolPentanonesmedicineMoleculeHumans[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringOral mucosaaroma persistenceSalivaAromaaroma metabolismVolatile Organic Compoundsbiologyoral mucosaChemistry010401 analytical chemistryaroma retentionMouth MucosaEthyl hexanoatefood and beverages04 agricultural and veterinary sciencesGeneral Medicinebiology.organism_classification040401 food scienceIn vitro0104 chemical sciencesmedicine.anatomical_structureBiochemistrymucosal pelliclearoma releasein vitro modelOdorants[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood ScienceFood chemistry
researchProduct

Chemical Composition and Antimicrobial Activity of the Essential Oils from Three Chemotypes of Origanum vulgare L. ssp. hirtum (Link) Ietswaart Growi…

2009

Essential oils obtained from inflorescences of three Origanum vulgare L.ssp. hirtum (Link) Ietswaart samples, growing wild in different locations in Campania (Southern Italy), were analysed. Three chemotypes were found: the first, with a prevalence of carvacrol/thymol; the second, characterized by the prevalence of thymol/alpha-terpineol; the third, featuring a prevalence of linalyl acetate and linalool. This chemical study attempts to provide a contribution in shedding light on the relationship between chemical composition and biotypes and/or chemotypes in Origanum vulgare ssp. hirtum. The essential oils were also evaluated for their antibacterial activity against 10 selected microorganism…

Chromatography GasAcyclic MonoterpenescarvacrolPharmaceutical ScienceCyclohexane MonoterpenesMicrobial Sensitivity TestsLinalyl acetateCymenesArticleGas Chromatography-Mass SpectrometryAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundOriganum vulgare ssp. hirtumantibacterial activitylcsh:Organic chemistryLinaloolOriganumthymolCyclohexenesDrug DiscoveryBotanyOils VolatilePlant OilsCarvacrollinalyl acetatePhysical and Theoretical ChemistryThymolessential oil compositionBacteriabiologyChemotypeOrganic ChemistryOriganum vulgare ssp. hirtum; essential oil composition; thymol; carvacrol; linalyl acetate; antibacterial activityOriganumbiology.organism_classificationAntimicrobialAnti-Bacterial AgentsItalychemistryChemistry (miscellaneous)MonoterpenesCymenesMolecular MedicineMolecules
researchProduct

Determination of key odorant compounds in freshly distilled Cognac using GC-O, GC-MS, and sensory evaluation

2004

This aim of this work was to identify the odorant compounds responsible for the typical sensory descriptors attributed to freshly distilled Cognac spirits, not matured in barrels. Panelists were first selected and trained for gas chromatography−olfactometry. Among the 150 volatile compounds identified by gas chromatography−mass spectrometry analysis, only 34 are mainly responsible for the odors detected in the spirits. The “butter” descriptor is explained by the presence of diacetyl, the “hay” descriptor by nerolidol, the “grass” descriptor mainly by Z-3-hexen-1-ol, but also by other compounds, the “pear” and “banana” descriptors by 2- and 3-methylbutyl acetates, the “rose” descriptor by 2-…

Chromatography GasMass spectrometry01 natural sciencesSensory analysisGas Chromatography-Mass Spectrometrychemistry.chemical_compound0404 agricultural biotechnologyLinalool[SDV.IDA]Life Sciences [q-bio]/Food engineeringHumansAromaComputingMilieux_MISCELLANEOUSNerolidolChromatographybiologyAlcoholic Beverages010401 analytical chemistryfood and beverages04 agricultural and veterinary sciencesGeneral Chemistry[SDV.IDA] Life Sciences [q-bio]/Food engineeringbiology.organism_classification040401 food scienceDiacetyl0104 chemical sciencesSmellchemistryOdorantsGas chromatographyGas chromatography–mass spectrometryGeneral Agricultural and Biological Sciences
researchProduct

Volatile Compounds of Lemon and Grapefruit IntegroPectin

2020

An HS-SPME GC-MS analysis of the volatile compounds adsorbed at the outer surface of lemon and grapefruit pectins obtained via the hydrodynamic cavitation of industrial waste streams of lemon and grapefruit peels in water suggests important new findings en route to understanding the powerful and broad biological activity of these new pectic materials. In agreement with the ultralow degree of esterification of these pectins, the high amount of highly bioactive &alpha

Citrusfood.ingredientPectinlemonPhytochemicalsPharmaceutical SciencegrapefruitArticleIndustrial wasteGas Chromatography-Mass SpectrometryAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundAdsorptionfoodLinaloolCitrus paradisilcsh:Organic chemistryDrug Discoveryhydrodynamic cavitation?-terpineolFood sciencePhysical and Theoretical ChemistryIntegroPectinpectinResidue (complex analysis)LimoneneVolatile Organic CompoundsMolecular Structureapplied_chemistryOrganic Chemistrycircular economywaste citrus peelBiosynthetic PathwaysTerpineolchemistryChemistry (miscellaneous)FruitMolecular Medicineα-terpineolGas chromatography–mass spectrometryCitric acidCitrus paradisi
researchProduct

Some Mass Spectrometry Contributions in the Study of Cultural Heritage

1997

In the last decades the application of various scientific methods and technologies to study materials and handicrafts of historical, artistic or archaeological interest have dramatically increased. These studies contribute to successfully solve various problems of identification, dating, utilization of artistically or historically important objects.

Cultural heritageHistoryLINALOOL OXIDEIdentification (biology)Visual arts
researchProduct

Capillary Liquid Chromatography for the Determination of Terpenes in Botanical Dietary Supplements

2021

Dietary supplements of botanical origin are increasingly consumed due to their content of plant constituents with potential benefits on health and wellness. Among those constituents, terpenes are gaining attention because of their diverse biological activities (anti-inflammatory, antibacterial, geroprotective, and others). While most of the existing analytical methods have focused on establishing the terpenic fingerprint of some plants, typically by gas chromatography, methods capable of quantifying representative terpenes in herbal preparations and dietary supplements with combined high sensitivity and precision, simplicity, and high throughput are still necessary. In this study, we have e…

Farnesenenatural productsPharmaceutical ScienceOrange (colour)01 natural sciencesArticleTerpenedietary supplementschemistry.chemical_compoundPharmacy and materia medica0404 agricultural biotechnologyLinaloolDrug DiscoveryLimoneneChromatography010401 analytical chemistryR04 agricultural and veterinary sciencesplant materials040401 food sciencecapillary liquid chromatography0104 chemical sciencesRS1-441chemistryMyrceneGreen coffee extractMedicineMolecular MedicineGas chromatographyterpenesPharmaceuticals
researchProduct

Aroma compound sorption by oak wood in a model wine

2001

Oak wood used for wine barrels was immersed into a model wine containing eight aroma compounds (e.g., aromatic and terpene alcohols, ethyl esters, and aldehyde), for which activity coefficients in water and model wine were determined using the mutual solubility measurement. A mass balance of these volatiles considering their reactivity in model wine was established. For most of the studied aroma compounds, and mainly for linalool and ethyl octanoate, a sorption behavior into wood was reported for the first time. This phenomenon was selective and could not be related to the solubilities in model wine and hydrophobicities of the studied aroma compounds, suggesting that acid-base and polar cha…

Food HandlingOrganolepticWinecomplex mixtures01 natural sciencesCHENEchemistry.chemical_compound0404 agricultural biotechnologyLinalool[SDV.IDA]Life Sciences [q-bio]/Food engineeringOrganic chemistryAroma compoundSolubilityAromaComputingMilieux_MISCELLANEOUSWineChromatographybiology010401 analytical chemistryfood and beveragesSorption04 agricultural and veterinary sciencesGeneral Chemistry[SDV.IDA] Life Sciences [q-bio]/Food engineeringbiology.organism_classification040401 food scienceWood0104 chemical sciencesKineticschemistryModels ChemicalSolubilityOdorantsWine chemistryVolatilizationGeneral Agricultural and Biological Sciences
researchProduct

De novo production of six key grape aroma monoterpenes by a geraniol synthase-engineered S. cerevisiae wine strain

2015

[Background] Monoterpenes are important contributors to grape and wine aroma. Moreover, certain monoterpenes have been shown to display health benefits with antimicrobial, anti-inflammatory, anticancer or hypotensive properties amongst others. The aim of this study was to construct self-aromatizing wine yeasts to overproduce de novo these plant metabolites in wines.

GeraniolWine aromaMonoterpeneAroma of wineGeranyl acetateBioengineeringWineSaccharomyces cerevisiaeBiologyApplied Microbiology and Biotechnologychemistry.chemical_compoundLinaloolNerolVitisFood sciencePlant ProteinsWineCitronellolResearchfungidigestive oral and skin physiologyfood and beveragesPhosphoric Monoester HydrolasesRecombinant ProteinsMonoterpene bioconversionchemistryBiochemistryFermentationOdorantsOcimum basilicumMonoterpenesSelf-aromatizing wine yeastsGeraniol synthaseMetabolic engineeringGeraniolBiotechnology
researchProduct