Search results for "nations"

Early Sacubitril/Valsartan-driven Benefit on Exercise Capacity in Heart Failure With Reduced Ejection Fraction: A Pilot Study

2017

Tight Link Between Our Sense of Limb Ownership and Self-Awareness of Actions

2007

Background and Purpose— Hemiparetic stroke patients with disturbed awareness for their motor weakness (anosognosia for hemiparesis/-plegia [AHP]) may exhibit further abnormal attitudes toward or perceptions of the affected limb(s). The present study investigated the clinical relationship and the anatomy of such abnormal attitudes and AHP. Methods— In a new series of 79 consecutively admitted acute stroke patients with right brain damage and hemiparesis/ -plegia, different types of abnormal attitudes toward the hemiparetic/plegic limb (asomatognosia, somatoparaphrenia, anosodiaphoria, misoplegia, personification, kinaesthetic hallucinations, supernumerary phantom limb) were investigated. Re…

Effectiveness and Tolerability of Fixed-Dose Combination Enalapril plus Nitrendipine in Hypertensive Patients Results of the 3-Month Observational, P…

2009

Background and objective: Monotherapy with any class of antihypertensive drug effectively controls blood pressure (BP) in only about 50% of patients. Consequently, the majority of patients with hypertension require combined therapy with two or more medications. This study aimed to evaluate the effectiveness (systolic BP [SBP]/diastolic BP [DBP] control) and tolerability of the fixed-dose combination enalapril/nitrendipine 10 mg/20 mg administered as a single daily dose in hypertensive patients. Methods: This was a post-authorization, multicentre, prospective, observational study conducted in primary care with a 3-month follow-up. Patients throughout Spain with uncontrolled hypertension (>= …

A case of post-traumatic complex auditory hallucinosis treated with rTMS.

2010

Previous studies of auditory hallucinations in schizophrenia found that the hallucinations were reduced by the application of transcranial magnetic stimulation (rTMS). Here we describe a case of traumatic brain injury associated with continuous music hallucinations. An MRI scan showed a structural lesion of the right temporal pole and a PET scan indicated a hyperactive area of the posterior right temporal lobe. We hypothesized that rTMS applied to the right temporal area would reduce this activity and the corresponding hallucinations. The patient's music hallucinations were significantly reduced by rTMS treatment. A PET scan following treatment also indicated that rTMS treatment reduced bra…

Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol

2020

A healthy intestinal barrier prevents uptake of allergens and toxins, whereas intestinal permeability increases following chemotherapy and in many gastrointestinal and systemic diseases and disorders. Currently, there are no approved drugs that target and repair the intestinal epithelial barrier while there is a medical need for such treatment in gastrointestinal and related conditions. The objective of this single-pass intestinal perfusion study in rats was to investigate the preventive cytoprotective effect of three mucosal protective drugs&mdash

Impact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study

2016

Rüdiger Sauer,1 Michaela Hänsel,2 Roland Buhl,3 Roman A Rubin,4 Marcel Frey,5 Thomas Glaab2,3 1Lung Centre Ulm, Ulm, Germany; 2Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany; 3Pulmonary Department, Mainz University Hospital, Mainz, Germany; 4Pulmonary Specialist Practice, Wiesbaden, Germany; 5Biometrics, Alcedis GmbH, Gießen, Germany Background: Maintaining and improving physical functioning is key to mitigating the cycle of deconditioning associated with chronic obstructive pulmonary disease (COPD). We evaluated the impact of free combination of the long-acting anticholinergic tiotropium plus the long-acting β2-agonist ol…

Evaluating the Possibilities of Improving the Quality of Tourism Services of the “Eco- Guesthouses” from Mărginimea Sibiului

2015

This paper provides an overview of the possibilities of improving the quality of tourism services of the ”eco-guesthouses” from Marginimea Sibiului in the context where the international studies indicate that lately tourists have become more experienced and expect good quality products in chosen holiday destinations. Currently, the international market of ecotourism has developed with 10-12% annually, having the fastest growth in the world tourism sector and tending to become an independent market segment, under the influence of factors such as: travelers prefer to choose educational holidays, their desire to escape to nature and spend quality time with friends or family, etc. In these circ…

Analysis of the impact of length of stay on the quality of service experience, satisfaction and loyalty

2017

Although length of stay is a relevant variable in destination management, little research has been produced connecting it with tourists' post-consumption behaviour. This research compares the post-consumption behaviour of same-day visitors with overnight tourists in a sample of 398 domestic vacationers at two Mediterranean heritage-and-beach destinations. Although economic research on length of stay posits that there are destination benefits in longer stays, same-day visitors score higher in most of the post-consumption variables under study. Significant differences arise in hedonic aspects of the tourist experience and destination loyalty. Thus, we propose that length of stay can be used a…

Transition towards a tourist innovation model: The smart tourism destination

2020

Implantation of the smart city model in intermediate tourist towns on their transition to becoming smart destinations involves an inescapable commitment to their habitat and improving the quality of civic life and the economy of cities through more sustainable and technologically advanced elements. Based on this work, the aim is to achieve an overview of the current smart cities paradigm from the standpoint of territorial interest groups, by analysing a tourist town on the Mediterranean coast (Gandia, Valencia) to diagnose its current status. The ultimate aim is to answer the question of whether these intermediate tourist cities are in a position to align themselves with the necessary requi…

Exploring the concept of perceived sustainability at tourist destinations: a market segmentation approach

2018

The concept of sustainability as perceived by tourists has rarely been studied and much less considered as a basis for segmentation. This article provides a conceptual framework based on tourists’ ...