Search results for "quantitative"
showing 10 items of 2409 documents
Network reconstruction for trans acting genetic loci using multi-omics data and prior information.
2022
Background: Molecular measurements of the genome, the transcriptome, and the epigenome, often termed multi-omics data, provide an in-depth view on biological systems and their integration is crucial for gaining insights in complex regulatory processes. These data can be used to explain disease related genetic variants by linking them to intermediate molecular traits (quantitative trait loci, QTL). Molecular networks regulating cellular processes leave footprints in QTL results as so-called trans-QTL hotspots. Reconstructing these networks is a complex endeavor and use of biological prior information can improve network inference. However, previous efforts were limited in the types of priors…
A New Approach to Investigate Students’ Behavior by Using Cluster Analysis as an Unsupervised Methodology in the Field of Education
2016
The problem of taking a set of data and separating it into subgroups where the ele- ments of each subgroup are more similar to each other than they are to elements not in the subgroup has been extensively studied through the statistical method of cluster analysis. In this paper we want to discuss the application of this method to the field of education: particularly, we want to present the use of cluster analysis to separate students into groups that can be recognized and characterized by common traits in their answers to a questionnaire, without any prior knowledge of what form those groups would take (unsupervised classification). We start from a detailed study of the data processing need…
Review: Highlights in recent applications of electronic tongues in food analysis
2010
This paper examines the main features of modern electronic tongues (e-tongues) and their most important applications in food analysis in this new century. The components of an e-tongue (automatic sampler, array of chemical sensors, and data processing system) are described. Applications commented include process monitoring, freshness evaluation and shelf-life investigation, authenticity assessment, foodstuff recognition, quantitative analysis, and other quality control studies. Finally, some interesting remarks concerning the strengths and weaknesses of e-tongues in food analysis are also mentioned.
Quantitative approaches for evaluating the influence of films using the IMDb database
2016
[EN] Why do films certain remain influential throughout film history? The purpose of this paper is to attempt to answer this question. To do so, we adopt some quantitative approaches that facilitate an objective interpretation of the data. The data source we have chosen for this study is the Internet Online Movie Database (IMDb), and in particular, one of its sections called "Connections", which lists references made to a film in subsequent movies and references made in the film itself to previous ones. The extraction and analysis of these networks of citations allows us to draw some conclusions about the most influential movies in film history, identifying their distinguishing features, an…
Quantifying Vegetation Biophysical Variables from Imaging Spectroscopy Data: A Review on Retrieval Methods
2019
An unprecedented spectroscopic data stream will soon become available with forthcoming Earth-observing satellite missions equipped with imaging spectroradiometers. This data stream will open up a vast array of opportunities to quantify a diversity of biochemical and structural vegetation properties. The processing requirements for such large data streams require reliable retrieval techniques enabling the spatiotemporally explicit quantification of biophysical variables. With the aim of preparing for this new era of Earth observation, this review summarizes the state-of-the-art retrieval methods that have been applied in experimental imaging spectroscopy studies inferring all kinds of vegeta…
Ligand-based discovery of novel trypanosomicidal drug-like compounds: In silico identification and experimental support
2010
Abstract Two-dimensional bond-based linear indices and linear discriminant analysis are used in this report to perform a quantitative structure–activity relationship study to identify new trypanosomicidal compounds. A database with 143 anti-trypanosomal and 297 compounds having other clinical uses, are utilized to develop the theoretical models. The best discriminant models computed using bond-based linear indices provides accuracies greater than 90 for both training and test sets. Our models identify as anti-trypanosomals five out of nine compounds of a set of already-synthesized substances. The in vitro anti-trypanosomal activity of this set against epimastigote forms of Trypanosoma cruzi…
A look into the future of the COVID-19 pandemic in Europe : an expert consultation
2021
How will the coronavirus disease 2019 (COVID-19) pandemic develop in the coming months and years? Based on an expert survey, we examine key aspects that are likely to influence COVID-19 in Europe. The future challenges and developments will strongly depend on the progress of national and global vaccination programs, the emergence and spread of variants of concern, and public responses to nonpharmaceutical interventions (NPIs). In the short term, many people are still unvaccinated, VOCs continue to emerge and spread, and mobility and population mixing is expected to increase over the summer. Therefore, policies that lift restrictions too much and too early risk another damaging wave. This ch…
Audiovisual constructs of Paralympic Games : scalarity and camera angle
2014
This research will analyze the variables differentiating between the audiovisual television of the XIII edition of the Paralympic Games and the Games of the XXIX Olympiad, held in Beijing from the 7th of September to the 17th, 2008. This study will serve as a methodological basis for similar future research. By means of a qualitative and quantitative methodology, this study also focuses on determining if TV representations of Paralympic sportspersons favour their social integration or if, on the contrary, lead to higher stigmatization.
Marketing Communications of Latvian Social Enterprises from a Consumer Perspective
2020
The purpose of this study is twofold - to contribute to the further understanding of social enterprises’ marketing by providing a consumers’ perspective on the content that social enterprises generate in order for them be to be able to better understand their strengths and weaknesses and to establish a reference point with regards the current situation to be able to compare and measure improvement in with regards social enterprise marketing in the future and, if needed, provide fact-based evidence to assist social enterprises in their call for support from public authorities. Among tasks of research are 1) analysis of recent scientific publications associate with social enterprises, their c…
Comparative study of reflectance cells for PLS-FTIR determination of sugars in soft drinks
1998
A comparative study has been carried out between a horizontal Attenuated Total Reflectance (h-ATR) cell and a Cylindrical Internal Reflection (CIR) cell (CIRCLE cell). Both cells were employed for the determination of glucose, fructose, sucrose and total sugar in soft drinks and fruit juices using absorbance measurements at two resolution values (4 and 8 cm–1). Data were processed by Partial Least Squares regression (PLS). Using a resolution of 4 cm–1, mean relative errors of prediction from 0.6% to 1.3% were obtained using the horizontal-ATR and from 0.6% to 2.8% using the CIRCLE cell resulting in a limit of detection from 0.03% in the case of sucrose to 0.21% for total sugar for the h-ATR…