Search results for "rafts"

showing 10 items of 228 documents

Dimethoxy Aromatic Compounds. VIII. Degenerate Dealkylation-Realkylation Reaction of 1-Bis(2,4-dimethoxyphenyl)-2-methylpropane.

1994

The condensation reaction under acid condition of the benzylic alcohols 1, 2 and 3 with the hexadeutero dimethoxybenzenes 4, 5 and 6 leads to the expected hexadeutero bis(dimethoxyphenyl)-2-methylpropanes 7, 8 and 9, respectively. However, the presence of both dodecadeutero and unlabelled 1-bis(2, 4-dimethoxyphenyl)-2-methylpropanes 10 and 11 indicates that 9 undergoes a rapid degenerate dealkylation-alkylation reaction.

chemistry.chemical_compoundchemistryDrug DiscoveryDegenerate energy levelsOrganic chemistryEtherGeneral ChemistryGeneral MedicineAlkylationCondensation reactionFriedel–Crafts reactionChemical and Pharmaceutical Bulletin
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Construction Guilds in Southern Italy and the Islands (15th-16th Centuries): Leadership and Rivalries

2020

In the South of Italy and the big islands, in counter-trend with respect to the rest of the peninsula, construction guilds know a renewed vitality between the last decades of 15th and the beginning of 16th centuries. Rules, prerogatives and operative modes are regulated by statutes, often undersigned by the masters included in the trade organization, mentioning also the other actors involved in the approval processes. The intertwining of these and other archival documents sometimes reveals the leading role played within the guild by masters that overcome the anonymity usually considered to be inherent in the corporate system. Comparing the rules and the boundaries among specific trades esta…

construction guilds construction in Sicily and Southern Italy building crafts in 15th and 16th centuriesSettore ICAR/18 - Storia Dell'Architettura
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Beyond Health and Happiness : An Exploratory Study Into the Relationship Between Craftsmanship and Meaningfulness of Sport

2021

Meaning in movement is an enduring topic in sport social sciences, but few studies have explored how sport is meaningful and for whom. The authors examined the relationships between demographic variables, meaningfulness of sport, and craftsmanship. Athletes (N = 258, 61.6% male, age ≥18) from the United Kingdom completed a demographic questionnaire, the Work and Meaning Inventory modified for sport, and the Craftsmanship Scale. Older age and individual sport significantly correlated with higher craftsmanship. Craftsmanship and religion were two independent predictors of meaningfulness, but emphasized somewhat different meaning dimensions. Meaningfulness in sport seems to be related to how a…

craftsmanshipurheilumielekkyysliikuntapsykologialiikuntasosiologiasporthuman activitiestyömeaningfulnessurheilijat
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Fontaines (Saône-et-Loire). Place de l’Église [notice archéologique]

2019

Le village actuel de Fontaines, situé à environ 8 km au N.-O. de Chalon-sur-Saône, se développe sur 1,5 km de long selon un unique axe E-O, depuis la montagne Saint-Hilaire à l’ouest, occupée au Néolithique puis durant l’Antiquité tardive et le haut Moyen Âge, jusqu’à l’église paroissiale Saint-Just, à l’est. Malgré une emprise limitée et contrainte par de nombreux réseaux existants, l’opération a permis de documenter l’environnement immédiat de l’église, occupé depuis l’Antiquité jusqu’à nos jours.

defenceBourgogne-Franche-Comtéfortificationchurchplace of worshipLate Middle Agessarcophagusbrickbuilding materialsMedieval PerioddeathGreco-Roman AntiquityMetropolitan FranceAntiquitymilitary buildingmelting crucible[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryRoman AntiquitymetallurgyEarly Middle AgescraftsLate EmpireEarly modern periodglassmaker's workshopditchchurchyardEarly Empirefunerary containerarchitectural terra-cottaRoman EmpireMiddle AgesSaône-et-Loire (department)Fontaines (Saône-et-Loire)
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IMPRESSIONI IN SICILIA

2014

“Impressioni in Sicilia” è la storia di una piccola azienda di design tessile che ha operato a Palermo dal 1974 fino al 1994. Proprietaria dell’impresa è Regine Hildebrandt, una svizzera trapiantata in Sicilia. La nascita di questo laboratorio s’inserisce in quel filone di esperienze finalizzate a incentivare il processo che vede l’incontro tra la cultura del progetto e la produzione artigianale, spesso legata alle tradizioni e alle risorse di alcuni territori. Gli oggetti progettati e realizzati da Regine hanno un valore durevole per la qualità dei disegni e dei materiali ma soprattutto, perché il suo progetto di ricerca è destinato all’identificazione e alla proposizione di “tratti cultur…

design screen printing art folk art art design craftsmanshipconception l'impression de l'écran l'art l'art populaire art design l'artisanatSettore ICAR/13 - Disegno Industrialedesign stampa serigrafica arte arte popolare art design artigianato
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Inhibition of KIF20A by BKS0349 reduces endometriotic lesions in a xenograft mouse model

2019

AbstractSeveral studies have suggested a possible etiological association between ovarian endometriosis and ovarian cancer. Evidence has shown that KIF20A overexpression might confer a malignant phenotype to ovarian tumors by promoting proliferation and inhibiting apoptosis. However, no data about the role of KIF20A in endometriosis have been described. In this study, the human endometrium (n = 4) was transfected by mCherry adenovirus and intraperitoneally implanted in mice. Subsequently, mice were divided in three groups (n = 8/group) that were treated with Vehicle, BKS0349 (KIF20A-antagonist) or cabergoline (dopamine receptor agonist) for 21 days. mCherry-labeled endometriotic lesions wer…

endometriosisEmbryologyCabergolineEndometriosisEndometriosisKinesinsMice NudeApoptosisBiologyPeritoneal DiseasesEndometriumAndrologyEndometriumMiceGeneticsmedicineAnimalsHumansKIF20AMolecular BiologyCell ProliferationTUNEL assayOptical ImagingapoptosisObstetrics and GynecologyCell BiologyCell cyclemedicine.diseaseDisease Models Animalcell proliferationmedicine.anatomical_structureReproductive MedicineApoptosisOvarian EndometriosisHeterograftsImmunohistochemistrycell cycleFemaleOvarian cancerDevelopmental BiologyMolecular Human Reproduction
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Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

2013

2,5-bis(3′-Indolyl)pyrroles, analogues of the marine alkaloid nortopsentin, were conveniently prepared through a three step procedure in good overall yields. Derivatives 1a and 1b exhibited concentration-dependent antitumor activity towards a panel of 42 human tumor cell lines with mean IC50 values of 1.54 μM and 0.67 μM, respectively. Investigating human tumor xenografts in an ex-vivo clonogenic assay revealed selective antitumor activity, whereas sensitive tumor models were scattered among various tumor histotypes.

ex-vivo xenograftsIndolesStereochemistryPharmaceutical ScienceMice NudeAntineoplastic AgentsArticleInhibitory Concentration 50MiceCell Line TumorNeoplasmsDrug Discoverybis-indolyl-pyrroles; nortopsentin analogues; marine alkaloids; antitumor; <i>ex-vivo </i>xenograftsIc50 valuesAnimalsHumansnortopsentin analoguePyrrolesClonogenic assayPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5Tumor Stem Cell AssayMice nudeantitumorAntitumor activityDose-Response Relationship DrugChemistryAlkaloidbis-indolyl-pyrroles; nortopsentin analogues; marine alkaloids; antitumor; ex-vivo xenograftsImidazolesTumor Stem Cell AssaySettore CHIM/08 - Chimica FarmaceuticaXenograft Model Antitumor Assaysbis-indolyl-pyrrolemarine alkaloidHuman tumornortopsentin analogueslcsh:Biology (General)Cell culturebis-indolyl-pyrrolesmarine alkaloidsMarine Drugs
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L'alimentation carnée à Aventicum/Avenches capitale des Helvètes (Ier s. - IVe s. apr. J.-C.) Suisse, canton de Vaud

2010

This first synthesis concerns the animal bones, discovered since 1975 in Aventicum, the capital of Roman Switzerland. It is supported by the analysis of several residential districts, public sectors and suburbs, which represent five hundred chronological complexes and 74000 animal bones, dated from the Ist, to the IVth Century AD. During these centuries, Aventicum was incorporated to the Roman province of Gallia Belgica, then was raised to the status of a colonia and finally declined with the Empire.The analysis of bones was made to study various mutations which occurred during the occupation of the city. They include an improvement of breeding techniques, a new internal city organisation, …

huntingbasse-courAvencheshabitatAntiquitéarchéozoologiemeat diet[SHS]Humanities and Social SciencesboucherieAntiquitySuissechassefarmyardagglomerationalimentation carnéeélevageartisanatresidential districtsagglomérationarchaeozoologybreedingcrafts.urbain[SHS] Humanities and Social SciencesbutcherySwitzerland
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Catalytic activity of solvated and unsolvated lanthanide halides in Friedel–Crafts acylations

2000

Abstract Anhydrous lanthanide halides — chlorides and bromides — can act as homogeneous catalysts of Friedel–Crafts acylations. The catalytic activity is related to the solubility of these anhydrous salts. More soluble THF or dioxane (Diox.) neodymium and samarium adducts are more active catalysts.

inorganic chemicalsLanthanideChemistryProcess Chemistry and Technologychemistry.chemical_elementHalideHomogeneous catalysisCatalysisCatalysisSamariumPolymer chemistryAnhydrousOrganic chemistryPhysical and Theoretical ChemistrySolubilityFriedel–Crafts reactionJournal of Molecular Catalysis A: Chemical
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UraniumIV and uranyle salts, efficient and reusable catalysts for acylation of aromatic compounds

2000

Abstract Uranium tetrachloride, uranyle chloride, fluoride and also nitrate or acetate are very efficient homogeneous catalysts for the Friedel–Crafts acylation of aromatic compounds. With uranyle salts, the reaction, carried under dry air, is highly specific and the mono- or bisacylation products are obtained in high yield. Uranyle catalyst can be quantitatively recovered and reused and the organic products are obtained free of uranium.

inorganic chemicalsProcess Chemistry and TechnologyHomogeneous catalysisEtherChlorideCatalysisCatalysisAcylationchemistry.chemical_compoundchemistrymedicineOrganic chemistryPhysical and Theoretical ChemistryUranium tetrachlorideFriedel–Crafts reactionFluorideNuclear chemistrymedicine.drugJournal of Molecular Catalysis A: Chemical
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