Search results for "recte"
showing 10 items of 463 documents
"Table 1.2" of "Probing the effects of strong electromagnetic fields with charge-dependent directed flow in Pb-Pb collisions at the LHC"
2020
Directed flow negative hadrons 5-40%
"Table 1.1" of "Probing the effects of strong electromagnetic fields with charge-dependent directed flow in Pb-Pb collisions at the LHC"
2020
Directed flow positive hadrons 5-40%
"Table 1.3" of "Probing the effects of strong electromagnetic fields with charge-dependent directed flow in Pb-Pb collisions at the LHC"
2020
Delta Directed flow hadrons
Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mec…
2014
Genomic imprinting is a form of epigenetic regulation that results in the expression of either the maternally or paternally inherited allele of a subset of genes (Ramowitz and Bartolomei 2011). This imprinted expression of transcripts is crucial for normal mammalian development. In humans, loss-of-imprinting of specific loci results in a number of diseases exemplified by the reciprocal growth phenotypes of the Beckwith-Wiedemann and Silver-Russell syndromes, and the behavioral disorders Angelman and Prader-Willi syndromes (Kagami et al. 2008; Buiting 2010; Choufani et al. 2010; Eggermann 2010; Kelsey 2010; Mackay and Temple 2010). In addition, aberrant imprinting also contributes to multige…
Effect of population patchiness and migration rates on the adaptation and divergence of vesicular stomatitis virus quasispecies populations
1999
The effect of migration among different isolated virus quasispecies populations on their adaptation and diversity was analysed through experimental evolution. Anin vitrocell system was employed to simulate migration of vesicular stomatitis virus between isolated homogeneous host cell populations. The results clearly demonstrated a positive correlation between the migration rate and the magnitude of the mean fitness reached by the virus quasispecies populations. The results also showed, although less clearly, that fitness differences among quasispecies decreased with the magnitude of migration. These results are in close agreement with predictions of standard population genetics theory. Thes…
Fitness Trade-Offs Determine the Role of the Molecular Chaperonin GroEL in Buffering Mutations
2015
Molecular chaperones fold many proteins and their mutated versions in a cell and can sometimes buffer the phenotypic effect of mutations that affect protein folding. Unanswered questions about this buffering include the nature of its mechanism, its influence on the genetic variation of a population, the fitness trade-offs constraining this mechanism, and its role in expediting evolution. Answering these questions is fundamental to understand the contribution of buffering to increase genetic variation and ecological diversification. Here, we performed experimental evolution, genome resequencing, and computational analyses to determine the trade-offs and evolutionary trajectories of Escherich…
The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus.
2004
6 pages, 3 figures.-- PMID: 15159545 [PubMed].-- PMCID: PMC420405.-- Supporting information (Table 3: Relevant information about each single-nucleotide substation mutant created) available at: http://www.pnas.org/content/101/22/8396/suppl/DC1
PROMOTING OF SELF-DIRECTED LEARNING IN COOPERATION WITH THE PARENTS FOR CHILDREN IN THE PRESCHOOL AGE
2015
Successful learning process in pre-school requires collaboration between children, educators and parents, whose primary goal is individual understanding of each child to promote his academic performance and personal development as a whole. This paper shows a pre-scientific and theoretical background of self-directed learning in preschool, as well as developed and theoretically substantiated child initiative research method "New friend". Particular attention is given to the promotion of the child's initiative, which is crucial in the process of self-directed learning. The empirical study of children's initiatives shows analysis of collaboration with the parents. A qualitative study reveals p…
Vérification des créances. Extinction par forclusion de la créance d'un sous-traitant contre l'entrepreneur principal en redressement judiciaire, Sub…
1991
International audience; (Versailles, 4 juill. 1991 ; Soc. des Ciments Français c/ SARL STECMI, Soc. Creusot Loire et Soc. EURAGE ; Paris, 27 nov. 1990, Soc. Parisienne d'Armatures pour Béton Armé c/ Soc. d'Energie Nucléaire Franco-belge des Ardennes)
Inhibition of glycosaminoglycan modification of perlecan domain I by site-directed mutagenesis changes protease sensitivity and laminin-1 binding act…
1998
AbstractGlycosaminoglycan attachment to perlecan domain I (173 residues) was completely prevented by site-directed mutagenesis of Ser-65, Ser-71 and Ser-76 as shown by recombinant production in mammalian cells. This did not interfere with the proper folding of the domain's SEA module but enhanced its sensitivity to neutral proteases. Lack of substitution also abolished binding to the two major heparin binding sites of laminin-1.