Search results for "x-ray structure"

showing 10 items of 32 documents

[2,6-Bis(di-tert-butylphosphinomethyl)phenyl-κ3P,C1,P′](trifluoroacetato)palladium(II)

2010

The Pd(II) atom in the title compound, [Pd(C(2)F(3)O(2))(C(24)H(43)P(2))], adopts a distorted square-planar geometry with the P atoms in a trans arrangement, forming two five-membered chelate rings. Four intra-molecular C-H⋯O hydrogen bonds occur. The crystal packing reveals one weak inter-molecular C-H⋯O hydrogen bond, which self-assembles the mol-ecules into infinite chains parallel to the b axis.

Metal-Organic PapersChemistryHydrogen bondchemistry.chemical_elementGeneral ChemistryCondensed Matter PhysicsBioinformaticspalladium ; pincer complexes ; hydrogen bonding ; X-ray structureCrystalCrystallographyAtomGeneral Materials ScienceChelationPalladiumActa Crystallographica Section E Structure Reports Online
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Revised structure of trans-resveratrol: Implications for its proposed antioxidant mechanism

2015

The crystal structure of trans-resveratrol has been redetermined by X-ray diffraction. The newly refined structure demonstrates that the previously reported, dynamically disordered hydrogen-bonding network is rather the superposition of two crystallographically independent molecules of trans-resveratrol. This latter arrangement possesses a well-defined hydrogen-bonding network in a unit cell of double the previously reported volume. While not meant as a criticism of the proposed antioxidant mechanism itself, the present studies clearly show that the X-ray diffraction data should no longer be used for its additional support.

Models MolecularDiffractionStereochemistryClinical BiochemistryStructure (category theory)Pharmaceutical ScienceCrystal structureCrystallography X-Ray010402 general chemistry01 natural sciencesBiochemistryAntioxidantsStructure-Activity RelationshipStilbenesDrug DiscoveryMoleculeMolecular BiologyMolecular StructureTrans-resveratrol010405 organic chemistryHydrogen bondChemistryOrganic ChemistryHydrogen Bondingdisorder0104 chemical sciencesCrystallographyResveratrolMechanism (philosophy)Molecular MedicineX-ray structuresuperstructureSuperstructure (condensed matter)Bioorganic & Medicinal Chemistry Letters
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Insights into functional aspects of centrins from the structure of N-terminally extended mouse centrin 1

2006

AbstractCentrins are members of the family of Ca2+-binding EF-hand proteins. In photoreceptor cells, centrin isoform 1 is specifically localized in the non-motile cilium. This connecting cilium links the light-sensitive outer segment with the biosynthetic active inner segment of the photoreceptor cell. All intracellular exchanges between these compartments have to occur through this cilium. Three-dimensional structures of centrins from diverse organisms are known, showing that the EF-hand motifs of the N-terminal domains adopt closed conformations, while the C-terminal EF-hand motifs have open conformations. The crystal structure of an N-terminally extended mouse centrin 1 (MmCen1-L) resemb…

Protein ConformationAmino Acid MotifsSequence HomologyPlasma protein bindingEF-handTroponin CMiceStructure-Activity RelationshipProtein structureCalcium-binding proteinConnecting ciliumCentrinAnimalsHumansPhotoreceptor CellsCiliaEF Hand MotifsProtein Structure QuaternaryChemistryEF handCiliumCalcium-Binding ProteinsTerminal Repeat SequencesCalcium-binding proteinSensory SystemsProtein Structure TertiaryCell biologyOphthalmologyCentrinCalciumTransducinsense organsX-ray structureProtein BindingVision Research
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Elucidating the catalytic reaction mechanism of orotate phosphoribosyltransferase by means of X-ray crystallography and computational simulations

2020

15 p.-8 fig.-2 tab.1 graph. abst.+ 8 fig. supl.-1 tab. supl.

PyrimidineStereochemistry010402 general chemistry01 natural sciencesCatalysisEnzyme catalysischemistry.chemical_compoundOrotidineNucleotideReaction mechanismchemistry.chemical_classificationMD simulations010405 organic chemistryHydrogen bondEnzyme catalysisGeneral ChemistryTautomer0104 chemical sciencesPyrimidine metabolismOrotate phosphoribosyltransferasechemistryPyrimidine metabolismOrotate phosphoribosyltransferaseQM/MM methodsX-ray structure
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DFT and experimental studies on structure and spectroscopic parameters of 3,6-diiodo-9-ethyl-9H-carbazole

2015

The first report on crystal and molecular structure of 3,6-diiodo-9-ethyl-9H-carbazole is presented. Experimental room-temperature X-ray and 13C chemical shift studies were supported by advanced theoretical calculations using density functional theory (DFT). The 13C nuclear magnetic shieldings were predicted at the non-relativistic and relativistic level of theory using the zeroth-order regular approximation (ZORA). Theoretical relativistic calculations of chemical shifts of carbons C3 and C6, directly bonded to iodine atoms, produced a reasonable agreement with experiment (initial deviation from experiment of 44.3 dropped to 4.25 ppm). The changes in ring aromatic character via simple harm…

Relativistic Effects3Simple harmonic motionDFT calculations010402 general chemistryRing (chemistry)13C NMR spectra01 natural sciencesMolecular physicsChemical shift indexCrystalZORA6-diiodo-9-ethyl-9H-carbazoleComputational chemistrycarbazoleFaculty of ScienceMolecule/dk/atira/pure/core/keywords/TheFacultyOfSciencePhysical and Theoretical Chemistry010405 organic chemistryChemistryChemical shiftAromaticityQuantum ChemistryCondensed Matter Physicscomputational chemistry0104 chemical sciencesZORA GIAO NMR calculationsNMR spectrocopyDensity functional theoryX-ray structureNMR; chemical shiftStructural Chemistry
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Molecular modeling and experimental studies on structure and NMR parameters of 9-benzyl-3,6-diiodo-9H-carbazole

2015

A combined experimental and theoretical study has been performed on 9-benzyl-3,6-diiodo-9H-carbazole. Experimental X-ray (100.0 K) and room-temperature 13C NMR studies were supported by advanced density functional theory (DFT) calculations. The non relativistic structure optimization was performed and the 13C nuclear magnetic shieldings were predicted at the relativistic level of theory using the Zeroth Order Regular Approximation (ZORA). The changes in the benzene and pyrrole rings compared to the unsubstituted carbazole or the parent molecules were discussed in terms of aromaticity changes using the harmonic oscillator model of aromaticity (HOMA) and the nucleus independent chemical shift…

Relativistic EffectsNICSMolecular modelGIAO NMR CalculationsDFT calculationsZORAchemistry.chemical_compoundComputational chemistrycarbazoleFaculty of ScienceHOMAMolecule13 C NMR spectra/dk/atira/pure/core/keywords/TheFacultyOfSciencePhysical and Theoretical ChemistryBenzeneHarmonic oscillator9-Benzyl-3CarbazoleChemical shiftAromaticityQuantum Chemistry6-diiodo-9H-carbazoleCondensed Matter Physicscomputational chemistryNMR spectrocopychemistryPhysical chemistryDensity functional theoryX-ray structureNMR; chemical shiftStructural Chemistry
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Single ion magnet behaviour in a two-dimensional network of dicyanamide-bridged cobalt(II) ions

2015

A novel two-dimensional coordination polymer of the formula [Co(dca)2(atz)2]n (1) resulted from assembling trans-bis(2-amino-1,3,5-triazine)cobalt(II) motifs by dicyanamide spacers. Variable-temperature dc and ac magnetic susceptibility measurements of 1 show that the high-spin cobalt(II) ions act as single ion magnets (SIMs).

Single ionCoordination polymerInorganic chemistrychemistry.chemical_elementMagnetic susceptibilityIonInorganic Chemistrychemistry.chemical_compoundchemistryMagnetPhysical chemistrySingle ion magnetX-ray structureCobaltDicyanamide
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Molecular recognition of N-acetyltryptophan enantiomers by β-cyclodextrin

2017

The enantioselectivity of β-cyclodextrin (β-CD) towards L- and D-N-acetyltryptophan (NAcTrp) has been studied in aqueous solution and the crystalline state. NMR studies in solution show that β-CD forms complexes of very similar but not identical geometry with both L- and D-NAcTrp and exhibits stronger binding with L-NAcTrp. In the crystalline state, only β-CD–L-NAcTrp crystallizes readily from aqueous solutions as a dimeric complex (two hosts enclosing two guest molecules). In contrast, crystals of the complex β-CD–D-NAcTrp were never obtained, although numerous conditions were tried. In aqueous solution, the orientation of the guest in both complexes is different than in the β-CD–L-NAcTrp …

Stereochemistry02 engineering and technology010402 general chemistry01 natural scienceslaw.inventionlcsh:QD241-441CrystalMolecular recognitionlcsh:Organic chemistrylawMoleculeCrystallizationenantiomeric discriminationlcsh:Sciencechemistry.chemical_classificationAqueous solutionCyclodextrinChemistryEstereoquímicaOrganic ChemistryN-acetyltryptophanQuímica021001 nanoscience & nanotechnologyN-acetyltryptophanNMR0104 chemical sciencesCrystallographyβ-cyclodextrinlcsh:QX-ray structureEnantiomer0210 nano-technology
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Synthesis of new half sandwich tetrachloro derivatives of molybdenum(V) and tungsten(V). X-ray structures of (C5HPri4)W(CO)3(CH3) and (C5Et5)WCl4

2002

International audience; The new synthetic intermediates (Ring)MCl4 [Ring=C5HPri4 or 4Cp, M=Mo, 2; Ring=C5Et5 or VCp, M=W, 4, Ring=4Cp, M=W, 6] containing sterically protecting cyclopentadienyl ligands have been synthesized. Along the synthetic pathway to 2, it was found that the treatment of [4CpMo(CO)3]− with an aqueous ferric solution according to the well established Manning procedure affords the hydride compound 4CpMo(CO)3H (1) by hydrolysis rather than the expected neutral dimer by oxidation. Compound 1 could be converted, however, to 2 upon oxidation with PhICl2 in good yields. Compound 4 is shown by a single crystal X-ray analysis to adopt a monomeric four-legged piano stool structur…

StereochemistryDimerchemistry.chemical_element010402 general chemistryRing (chemistry)01 natural sciencesBiochemistryTungstenInorganic Chemistrychemistry.chemical_compoundCyclopentadienyl complexOrganometallic synthesisMaterials Chemistrymedicine[CHIM.CRIS]Chemical Sciences/Cristallography[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical ChemistryBulky cyclopentadienyl ligandsMolybdenumAqueous solution010405 organic chemistryHydrideOrganic Chemistry0104 chemical sciencesCrystallographychemistryMolybdenumFerricX-ray structureSingle crystalmedicine.drug
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Preparation of trichloro- and tribromocyclopentadienyltungsten(IV)

2000

International audience; The thermal decarbonylation of (Ring)WX3(CO)2 in refluxing toluene has led to the preparation of the CO-free compounds [(Ring)WX3]2 [Ring=η5-C5H5 (Cp) and X=Cl (1a) or Br (1b); Ring=η5-C5H4Me (Cp′), X=Cl (2a) or Br (2b); Ring=η5-C5Me5 (Cp*), X=Cl (3)]. The NMR properties of these molecules are consistent with diamagnetism and thereby indicate a different structure from that of the paramagnetic molybdenum analogues. Compounds 1a and 2a react with dppe to afford mononuclear 18-electron adducts, (Ring)WCl3(dppe) (Ring=Cp (4) or Cp′ (5)). The X-ray structure of 5 shows a pseudo-fac-octahedral geometry with the dppe ligand occupying two equatorial (e.g. cis relative to Cp…

Stereochemistrychemistry.chemical_element010402 general chemistryRing (chemistry)01 natural sciencesBiochemistryMedicinal chemistryCO-free compoundsTungstenAdductInorganic ChemistryParamagnetismchemistry.chemical_compoundMaterials ChemistryMolecule[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical Chemistry010405 organic chemistryLigandOrganic ChemistryDecarbonylationMetal–metal bondsToluene0104 chemical sciences3. Good healthDiamagnetismchemistryMolybdenumX-ray structuresJournal of Organometallic Chemistry
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