0000000000013004

AUTHOR

Pietro Messina

0000-0001-7409-4474

A New System for Choosing the Form and Size of Complete Denture Anterior Teeth

Introduction: In the absence of pre-extraction records, the choice of the size an form of anterior complete denture teeth can be extremely subjective. Several clinical and statistical parameters are usually used for choosing the correct size and form of the complete denture anterior teeth. Clinical Innovation: The technique consists of a system that allows the dentist to choose and, if necessary, easily change the dental mold during maxillomandibular recording session. The unique feature of the system is that six teeth of each mold are represented by veneers, which are connected to each other on the lingual surface by a fiber that allows each veneer some degree of movement. Discussion: This…

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CAPSAICIN STIMULATION AND NEUROGENIC EXPERIMENTALLY INDUCED INFLAMMATION OF THE HUMAN LABILA MUCOSA

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Diagnostic evaluation of serial sections of labial salivary gland biopsies in Sjögren's syndrome.

OBJECTIVES: Sjögren's syndrome is a chronic inflammatory disease. The detection of chronic inflammatory infiltrates containing >50 lymphocytes (lymphocytic focus) per 4 mm2 tissue in minor salivary gland biopsies is a diagnostic parameter of the disease. The aim of the study was to examine if an increase in the tissue area of a single minor labial salivary gland biopsy through serial histological sections in patients affected by primary Sjögren's syndrome could facilitate the detection of the diagnostic focus score (grades >1 or >2). METHODS: We observed 24 labial salivary gland biopsies from patients affected by primary Sjögren's syndrome, diagnosed according to the clinical-laboratory cri…

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Evaluation of labial microvessels in Sjogren syndrome: A videocapillaroscopic study

Summary Sjogren's syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of exocrine glands, especially salivary and lachrymal ones, leading to xerostomia, parotid gland enlargement, and xerophtalmia. SS may occur alone (primary) or in association with almost any of the autoimmune rheumatic diseases (secondary), the most frequent being rheumatoid arthritis. The aim of this study is to describe the capillaroscopic pattern of the labial mucosa in patients with SS. Methods A total of 20 patients affected by SS and 20 healthy controls were examined. The patients with conditions that compromise microcirculation, such as diabetes, hypertens…

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THE ROLE OF NEUROMODULATORS (SUBSTANCE P AND CALCITONIN GENE-REòATED PEPTIDE) IN THE DEVELOPMENT OF NEUROGENIC INFLAMMATION IN THE ORAL MUCOSA

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B-Lactam antibiotics in daily dentistry practice: a critical review

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Microvascular abnormalities in patients with rheumatoid arthritis.

Summary Microvascular involvement represents one of the first apparent steps in many autoimmune diseases such as rheumatoid arthritis (RA). Early in the disease, peripheral microangiopathy may be easily recognized and studied by videocapillaroscopy. The aim of this study has been to observe the differences in labial microcirculation between healthy patients and patients suffering from RA. A total of 30 healthy patients and 30 patients suffering from RA were examined. The patients with conditions known to compromise microcirculation, such as diabetes, hypertension, or some pharmacological treatments were not included in the study. All the patients were non-smokers. Labial capillaroscopy was …

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Nf-k B as target of Pharmacological Treatment

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Multiple sclerosis: oral manifestation and dental implications

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CAPILLAROSCOPIC AND HISTOLOGIC EXAMINATION OF THEH UMAN LABIAL MUCOSA: A NEW NON-INVASIVE METHODOLOGY COMPARED WITH THE HISTOLOGICA EXAM

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Preliminary morpho-structural studies during endodontic treatment with Ni-Ti 55-45 instruments

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Penphigus Vulgaris in a mediterranean Young Adult Manifesting as Desquamative Gingivitis

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Oral microcirculation in post-menopause: a possible correlation with periodontitis

Objectives: The reduction in the level of oestrogen, typical in menopause, has some effect on the health of the oral cavity. In fact, post-menopausal women present more severe periodontal disease than pre- menopausal women. Numerous factors can be held to be responsible for this increase, among which are the effects of oestrogens on the oral epithelium, on the salivary glands, on bone tissue and on the endothelium. Our double blind study aims to evaluate the possible variations in oral microcirculation in post-menopausal women. Methods: Twenty-seven women in post-menopause (age: Mean ± SD: 57.3 ± 8.73) and 27 women in pre-menopause (age: Mean ± SD: 27.77 ± 3.56) were examined. Oral microcir…

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THE ELEVATION OF THE MAXILLARY SINUS: OUR CLINICAL EXPERIENCE

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ORAL CAPILLAROSCOPIC: a new diagnostic method.

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Microvascular periodontal alterations: A possible relationship between periodontitis and rheumatoid arthritis.

Abstract BACKGROUND: Microvascular involvements represent one of the first steps in many autoimmune diseases such as rheumatoid arthritis (RA). The aim of this study was to investigate the differences in periodontal microcirculation between healthy subjects and patients suffering from RA. METHODS: Thirty healthy subjects and 30 patients suffering from RA were examined. The patients who showed conditions known to compromise microcirculation, such as diabetes, hypertension, pharmacological treatments, were not included in the group of healthy patients. All the patients were non-smokers. Periodontal capillaroscopy was used to investigate the characteristics of microcirculation. Visibility, cou…

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LESIONI ORALI E CERVICALI ASSOCIATE A PAPILLOMA VIRUS UMANO

The aim of this review is to carry out a quick excursus on the epidemiological and clinical aspect of oral and cervical lesions induced by human papillomavirus (HPV) infection and on the way this virus is transmitted. HPV infection is transmitted above all through vaginal or anal sexual relations with partners carrying the virus. Also other types of sexual relations, such as oral sex, can be a vehicle of transmission, though much more rarely. In literature there is not enough data proving that oral-genital contact can really be a vehicle of transmission for human papillomavirus. It can be concluded, therefore, that evidences in further studies with a large sample group of patients who pract…

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Morphological characteristics of microcirculation in oral lichen planus involving the lateral border of the tongue.

Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations. The aim of the study was to evaluate the morphological characteristics of microcirculation of lingual lichen planus (LLP). Twenty patients (10 patients with LLP and 10 healthy patients) were examined by means of videocapillaroscopy. The left margin of the lingual mucosa was examined in each patient. The capillary loop length, loop diameter, and capillary density were analyzed on ev…

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PANORAMIC PERIODONTAL CAPILLAROSCOPY: A NEW DIAGNOSTIC METOD

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IGIENE ORALE NEI PAZIENTI NON VEDENTI

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Photobiomodulation Therapy in the Management of Burning Mouth Syndrome: Morphological Variations in the Capillary Bed

Burning mouth syndrome (BMS) is an idiopathic condition that manifests itself primarily with the onset of a burning sensation. The aim of this research was to perform photobiomodulation therapy (PBM) using a diode laser on the oral mucosa of BMS patients, followed by an objective evaluation of the morphological changes in the vascular bed underlying the mucosa using polarized light videocapillaroscopy. A group of 40 patients were included in the study. The patients were randomly divided into two groups (using simple randomization) as follows: 20 patients were assigned to the laser group and 20 patients were assigned to the placebo group. Each patient of the laser group received eight irradi…

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PRELIMINARY OBSERVATIONS ABOUT CAPILLAROSCOPIC AND HISTOLOGIC EXAMINATIONS OF THE HUMAN LABIAL MUCOSA

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FRATTURA DI IMPIANTI DENTARI: A CASE REPORT

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Periodontal Alteration of the Microcirculation and Hypercholesterolemia: A Possible Correlation?

OBJECTIVE: We evaluated the morphological and parametric characteristics of the periodontal microcirculation in patients diagnosed as having hypercholesterolemia and high levels of low-density lipoprotein (LDL). METHODS: Forty patients were recruited, 20 of whom were affected by hypercholesterolemia and 20 of whom were considered healthy. A videocapillaroscopic examination was carried out on the periodontal mucosa in the proximity of the frenulum (II, V sextant). RESULTS: The difference between the parameters of the hypercholesterolemia group and the control group was evaluated with the Mann-Whitney U-test for non-parametric ordinal data; the level of significance being P < 0.05. The videoc…

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HODKIN'S DISEASE AND ITS ORAL MANIFESTATIONS

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LinguAPP: An m-Health Application for Teledentistry Diagnostics

An Android/iOS application for low-cost mobile devices to aid in dental diagnosis through questionnaire and photos is presented in this paper. The main purposes of our app lie in the ease of use even for nonexperienced users, in the limited hardware requirements that allow a wide diffusion, and in the possibility to modify the questionnaire for different pathologies. This tool was developed in about a month at the beginning of the COVID-19 (SARS-CoV-2) pandemic and is still in use in Italy to allow support to patients without going to the hospital, if not strictly necessary.

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SYSTEMIC SCLEROSIS:DESCRIPTION AND DIAGNOSTIC ROLE OF ORAL PHENOMENA

This study was designed to describe and evaluate the eventual prodromic role of the orofacial phenomena encountered in patients suffering from systemic sclerosis. Phenomena preceding the diagnosis and events that occured at the onset of systemic sclerosis were considered. Sclerodermic patients were monitored to implement a secondary preventive plan for controlling oral injuries caused by developing systemic sclerosis.

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In vivo evaluation of labial microcirculation in diabetics: a comparison with healthy subjects.

AIM: Diabetes mellitus, a systemic chronic disease considered an epidemic by the World Health Organization (WHO) due to the rate of increase in the prevalence of diabetes, is a cause of microvascular and macrovascular complications leading to a significant burden for the individual and society. The aim of this study was to evaluate in vivo the effects of type II diabetes mellitus on the microcirculation of oral mucosa. METHODS: Forty-six subjects, 23 patients with type II diabetes mellitus (10 men, 13 women) and 23 healthy patients (9 men, 14 women) were examined in our laboratory. Oral microcirculation was evaluated on labial mucosa using oral video-capillaroscopy: a diagnostic method that…

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[Oral capillaroscopy: a new diagnostic method].

The morphological-functional study of microcirculation is of fundamental importance; in fact, the microvascular bed is directly involved both in autoimmune etiopathogenesis pathologies, and in acute and chronic inflammatory etiopathogenesis pathologies. Oral capillaroscopy is a very stimulating method for studying microcirculation, because of the possibility of studying small vessels in vivo by means of a microscope. Today, it is becoming more reliable thanks to the improvement of the observation tools (photography, videomicroscopy).

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Diabetic Microagiopathy of Oral Mucosa Depends on Disease Duration and Therapy

Background: Diabetes mellitus is a chronic degenerative systemic disease whose prevalence is increasing. This paper aims to evaluate the effects of diabetic microangiopathy, depending on its duration and the type of treatment administered, by using polarized light videocapillaroscopy of the oral mucosa. Material/Methods: We enrolled 120 subjects: 60 healthy subjects and 60 patients with diabetes mellitus. In turn, patients were divided into 3 subgroups according to the type of diabetes, the duration of the disease, and the type of treatment administered. A videocapillaroscopic examination of the oral mucosa was carried out on the diabetic and healthy subjects. Results: Changes in microcircu…

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EVALUATION OF THE CLINICAL AND HISTOLOGICAL EFFECTIVENESS OF ISOTRETIONIN IN THE THERAPY OF ORAL LEUKOPLAKIA.TEN YEARS OF EXPERIENCE: IS MANAGEMENT STILL UP-TO-DATE AND EFFECTIVE?

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Inhalatory anaesthesia Vs. TIVA in oral surgery and laryngectomy with lateral clearing: our experience

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Color and photography in the restorative dentistry. A brief communication about color temperature, dental color and the use of light and photography in dental practice

Relevance. Optical properties of dental tissues can be captured by photography, considering the characteristics of the light sources. Therefore photography might become a way to communicate the color and the characterizing aspects of the teeth, reducing the misunderstandings between the dental practice and the laboratory in the project of dental restoration. Purpose. To illustrate some ways of using the current photographic technology to document teeth color correctly, and to be able to communicate it without misunderstandings and to replicate it in a simple way. Materials and methods. The photographs were taken using Nikon D500 digital camera, Nikkor 60 mm 2.8 macro lens, Nikon SB-700 Spee…

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Smoking a Dangerous Addiction: A Systematic Review on an Underrated Risk Factor for Oral Diseases

Despite growing knowledge of the adverse effects of cigarette smoking on general health, smoking is one of the most widely prevalent addictions around the world. Globally, about 1.1 billion smokers and over 8 million people die each year because of cigarette smoking. Smoking acts as a source for a variety of oral and systemic diseases. Various periodontal issues such as increased pocket depth, loss of alveolar bone, tooth mobility, oral lesions, ulcerations, halitosis, and stained teeth are more common among smokers. This systematic review was conducted according to the guidelines from PRISMA, and research articles were retrieved from the Web database sources on 31 May 2021. The quality of …

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A Vaccine Construction against COVID-19-Associated Mucormycosis Contrived with Immunoinformatics-Based Scavenging of Potential Mucoralean Epitopes

Mucormycosis is a group of infections, caused by multiple fungal species, which affect many human organs and is lethal in immunocompromised patients. During the COVID-19 pandemic, the current wave of mucormycosis is a challenge to medical professionals as its effects are multiplied because of the severity of COVID-19 infection. The variant of concern, Omicron, has been linked to fatal mucormycosis infections in the US and Asia. Consequently, current postdiagnostic treatments of mucormycosis have been rendered unsatisfactory. In this hour of need, a preinfection cure is needed that may prevent lethal infections in immunocompromised individuals. This study proposes a potential vaccine constru…

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Correlation of " in vivo" microcirculation and degeneration of the basal cells of the epithelium in lingual lichen planus

Background: Oral lichen planus is an inflammatory chronic disease with an autimmune pathogenesis and unknown etiology that affects oral mucosa, with or without the involvement of the skin and other mucous membranes. The principal histological characteristics are the degeneration of the basal cell layer and the abnormal infiltration of inflammatory cells into the subepithelial layer of connective tissue. Objectives: This study is aimed to appraise if lingual lichen planus (LLP) is sustained by alteration of the oral microcirculation and if this abnormal vascularisation increases the degeneration of basal keratinocytes and the disruption of the basement membrane. Materials and Methods: Fiftee…

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CAPSAICIN STIMULATION AND NEUROGENIC EXPERIMENTALLY INDUCED INFLAMMATION OF THE HUMAN LABIAL MUCOSA

Background. The neurogenic inflammation depends on the neuromodulator release by peripheral nervous termi−nations. A series of different studies proved the existence of a neurogenic phlogosis (NP) in different body sites.Only experiences on rat managed to induce NP at the oral mucosa level.Objectives. Inducing NP at the human mucosa level.Material and Methods. Two groups of patients (group A: M/F: 8/7; mean: 41.14 ± 12.4; range: 24–60; group B:M/F: 8/7; mean: 41.21 ± 12.39; range: 23–60) were examined in authors’ laboratory. The NP was experimentallyinduced at the lower lip mucosa level after topically applying capsaicin. The vascular consequences were observedthrough computer videocapillar…

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MICROVASCULAR CHARACTERISTICS OF THE HUMAN FILIFORM PAPILLAE:A VIDEOCAPILLAROSCOPIC STDY.

The aim of this study was to observe the microcirculation characteristics of the human filiform papillae in healthy patients in vivo. Twenty healthy patients were examined using lingual capillaroscopy to investigate the characteristics of microcirculation of the human filiform papillae. Visibility, course, tortuosity, as well as the possible presence of microhemorrhages, the average caliber of the capillary loops and the number of visible capillary loops per square millimeter were evaluated for each patient. The investigation was simple, non-invasive and repeatable for each patient. Microcirculation architecture was characterized by a network of capillaries in polygonal mesh with parallel o…

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CANALAR REPROCESSING WITH NI-TI INSTRUMENTS: OUR EXPERIENCE.

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Implant fracture. Case report

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Efficacy of an oral health training programme for visually impaired individuals

The aim of this study was to evaluate the efficacy of an oral health training programme for visually impaired individuals and their families or caretakers. The training programme was based on reliance on the other senses. The study was performed at an institute for the blind in Palermo (Italy). Oral hygiene and health status of 30 visually impaired subjects aged 15-60 years were evaluated by interview and use of the Decayed Missing Filled (DMF) and Simplified Oral Hygiene by Green-Vermillion (OHI-S) indices. Subjects underwent an oral health training programme at the end of which their oral hygiene and health status was once again evaluated. Participants were found to have poor oral hygiene…

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PRELIMINARY STUDIES OF MICROCIRCULATORY IN SEPSI ITALIAN JOURNAL OF ANATOMY AND EMBRIOLOGY

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Nutrition and oral health

Diet plays a key role in oral disease prevention. The aims of this report were to review the causes and consequences of a poor diet and its interrelationship with oral health. The first signs of micronutrient deficiencies are often manifest in the oral tissues. Consequently, the dentist has a considerable role in the early diagnosis of malnutrition. Furthermore, optimizing oral health is important in maximizing functional capacity to consume a healthful and varied diet. A varied diet is, otherwise, fundamental to save oral health.

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Caratteristiche capillaroscopiche del microcircolo labiale di pazienti affetti da tiroidite di Hashimoto.

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PRELIMINARY TREATMENT ABOUT MODIFICATON OF THE MORPHOLOGY OF THE TEETH DURING ORTHODONTIC TREATMENT

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CANALAR REPROCESSING G WITH NI-TI INSTRUMENTS: OUR EXPERIENCE.

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Topical capsaicin application and axon reflex vasodilatation of the tongue: A videocapillaroscopic study

The aim of this study was to evaluate the effects of topical capsaicin application on human lingual mucosa and to assess if neurogenic inflammation might have a role in the pathogenesis of lingual diseases. Thirty patients (16 males and 14 females; mean age: 41.46 +/- 11.8 years; range: 23-60) were examined in our laboratory. The neurogenic inflammation was experimentally induced in the lingual mucosa close to 1) the left margin of the tongue and 2) the right margin of the tongue after ipsilateral nerve trunk anesthesia. The characteristics of lingual microcirculation were observed using computerized videocapillaroscopic techniques. The vasodilatation was observed close to the left margin o…

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Vasodilatation of human gingiva and neurogenic inflammation

BACKGROUND: Neurogenic Inflammation (NI) is the consequence of amyelinic-sensitive neuron activation. Recent studies on rats proved that NI could be experimentally induced by topical capsaicin application. The aim of this study is to evaluate the effects of topical capsaicin application on human periodontal mucosa and to assess if NI might have a role in the pathogenesis of periodontal diseases. METHODS: 15 patients were examined in our laboratory. NI was experimentally induced in the gingival mucosa close to: (1) the interdental papilla corresponding to the upper central incisors; (2) the interdental papilla corresponding to the lower left lateral incisor and canine after ipsilateral nerve…

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A Multicultural Demographic Study to Evaluate the Impact of the SARS-CoV-2 Pandemic on the Job Satisfaction across the Dental Industry

ABSTRACT Objective: To evaluate the difference in working conditions as perceived by dentists during the pandemic and their professional satisfaction levels. Material and Methods: An online survey was conducted using the convenience and snowball sampling methods. Two hundred seventy-two respondents across various countries answered information related to socio-demographic data and work satisfaction levels during the SARS-CoV-2 pandemic. Results: 40.1% of dentists reported dissatisfied with their current work, while another 13.6% of dentists fell in the extremely dissatisfied category. 22.8% of dentists were significantly dissatisfied with their current income. Furthermore, 38.4% of the dent…

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STUDY OF MICROCIRCULATION IN ORAL LICHEN PLANUS BY VIDEOCAPILLAROSCOPY

Objective. The aim of this study was to evaluate “in vivo” the oral microcirculatory characteristics in patients with oral lichen planus (OLP) and to discover any differences in microcirculation in comparison with healthy patients. Study design. Twenty patients with established diagnosis of OLP and 20 healthy patients were examined in our laboratory by means of contact optical probe videocapillaroscopy. The examined areas for each patient were the right and the left buccal mucosae. Capillary density and total capillary diameter, as well as afferent and efferent loop diameter were studied; the discovery of characteristic (tortuous, branched) loops was also investigated. Results. The results …

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Microvascular Characteristics of the Human Interdental Papilla

The aim of this study was to observe the microcirculation characteristics of the human interdental papilla in healthy patients in vivo. Twenty healthy patients were examined. Capillaroscopy was used to investigate the characteristics of microcirculation of the human periodontal mucosa. Visibility, course, tortuosity, as well as the average caliber of the capillary loops and the number of visible capillary loops per square millimeter were evaluated for each patient. The investigation of gingival mucosa revealed capillary loops with a course both parallel and perpendicular to the surface. Our study has pointed out that capillaroscopy is a reliable method to study periodontal microcirculation …

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Angiogenesis in oral lichen planus: an in vivo and immunohistological evaluation.

Oral lichen planus (OLP) is an autoimmune disease with an inflammatory pathogenesis. The angiogenetic phenomenon is a mechanism at the base of the pathogenesis of chronic inflammatory processes. The aim of this research is to evaluate the angiogenetic phenomenon, comparing an in vitro method with an in vivo one. Thirty OLP patients and 30 healthy subjects were enrolled in the study. Immunohistochemical analysis of the vascular-endothelial growth factor (VEGF) and vascular-endothelial adhesion molecules were carried out by the means of primary antibodies and anti-CD34, anti-VEGF, anti-CD106 antigen (VCAM-1) and anti-CD54 antigen (ICAM-1). Capillary density and others capillaroscopic paramete…

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Herbal Medications in Endodontics and Its Application—A Review of Literature

Herbal products are gaining popularity in dental and medical practice nowadays due to their biocompatibility, higher antimicrobial activity, antioxidant and anti-inflammatory properties. Herbal medicine has experienced rapid growth in recent years due to its beneficial properties, ease of availability, and lack of side effects. As pathogenic bacteria become more resistant to antibiotics and chemotherapeutic agents, researchers are becoming more interested in alternative products and treatment choices for oral diseases. As a result, natural phytochemicals separated from plants and utilized in traditional medicine are suitable substitutes for synthetic chemicals. The aim of this review articl…

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Preliminary observation of orthodontics self adhesive cement

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The Exponential Rise of Teledentistry and Patient-Oriented Protective Measures in Southeast Asian Dental Clinics: Concerns, Benefits, and Challenges

In the Southeast Asian region, various policies have been advocated by health regulatory bodies that entail protective measures such as face masks, gloves, maintaining distance in public areas, and more. These protective measures are aimed at helping reverse the growth rate of the coronavirus. Dentists in this region have incorporated several changes to their practices to help minimize risks of person-to-person transmission inside dental offices. This narrative review aimed to provide an in-depth overview of the current situation in the Southeast Asian region regarding the use of teledentistry during the pandemic. Teledentistry involves the transfer of patient information across remote dist…

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Chronic hyperplastic candidosis: a pilot study of the efficacy of 0.18% isotretinoin.

Management of oral candidiasis depends on an accurate diagnosis, identification and elimination of predisposing factors, and, often, use of antifungal agents. Chronic hyperplastic candidosis (CHC) is considered a premalignant lesion of the oral mucosa, occurring as speckled or homogeneous white lesions. If the lesions are untreated, a minor proportion may become dysplastic and progress to carcinoma. The traditional treatment of this lesion is based on the use of antifungal agents. The aim of this study was to examine the efficacy of 0.18% isotretinoin for treatment of nystatin-resistant candidiasis. Isotretinoin was administered topically twice a day for one month to six patients affected b…

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Capillaroscopic and histological examination of the human labial mucosa: a new non invasive methodology compared with the histological exam

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Changes of oral microcirculation in chemotherapy patients: A possible correlation with mucositis?

The aim of this investigation is to appraise labial oral microcirculation in chemotherapy patients to clarify the effects of cytotoxic agents on oral microvessels. Twenty-five patients with diagnosis of head and neck tumors were recruited in the study. All the patients were submitted to chemotherapy. Labial oral microcirculation was evaluated on labial mucosa using oral videocapillaroscopy. The statistical significance was checked with the Mann–Whitney U-test (P < 0.05). The analysis of videocapillaroscopic patterns showed statistically significant variations relative to the diameter of the incoming loop; the diameter of the outgoing loop; and loop tortuosity. This study shows that capillar…

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PANORAMIC PERIODONTAL CAPILLAROSCPY: A NEW DIAGNOSTIC METHOD

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Microvascular characteristics of the human filiform papillae: a videocapillaroscopic study

The aim of this study was to observe the microcirculation characteristics of the human filiform papillae in healthy patients in vivo. Twenty healthy patients were examined using lingual capillaroscopy to investigate the characteristics of microcirculation of the human filiform papillae. Visibility, course, tortuosity, as well as the possible presence of microhemorrhages, the average caliber of the capillary loops and the number of visible capillary loops per square millimeter were evaluated for each patient. The investigation was simple, non-invasive and repeatable for each patient. Microcirculation architecture was characterized by a network of capillaries in polygonal mesh with parallel o…

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Tooth-implant connection in removable denture.

When the patient cannot be rehabilitated with a fixed denture, or when he does not succeed in adapting to a traditional removable denture, a possible alternative solution consists in the use of a limited number of implants, placed in strategic positions in the arches of the patient, and subsequently connected to their residual teeth. The aim of this review is to evaluate the progress made on connections between teeth and implants in removable denture, to analyze their advantages and disadvantages and to compare the survival rate, both of the teeth and of the implants used as abutments, present in the various studies taken into examination, with the aim of being able to evaluate the effectiv…

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PRELIMINARY TREATMENT ABOUT MODIFICATION OF THE MORFOLOGY OF THE TEETH DURING ORTODONTHIC TREATMENT

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Hashimoto's Thyroiditis: Labial Capillary Microscopy

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PERIODONTAL PANORAMIC CAPILLAROSCOPY: A NEW DIAGNOSTIC METHOD

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VIDEOCAPILLAROSCOPIA DELLA MUCOSA ORALE

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Linee guida in ortodonzia e attuale valutazione dei profili di responsabilità

Alla luce della nuova legge entrata in vigore in Italia, si discute il valore protettivo delle linee guida in ortodonzia sotto il profilo medico-legale. OBJECTIVES. In view of the Italian law recently come into force, this study aims at discussing the protective value of orthodontic guidelines in terms of legal medicine. MATERIALS AND METHODS. A review of orthodontic guidelines was conducted, including general orthodontic guidelines as well as specific guidelines for clinical and surgical cases. RESULTS AND CONCLUSIONS. Orthodontic practices envisaging professional liability include diagnosis, prevention, interception, care planning and treatment of all types of malocclusion (even when asso…

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Oral microcirculation in post-menopause: a possible correlation with periodontitis

doi: 10.1111/j.1741-2358.2011.00608.x Oral microcirculation in post-menopause: a possible correlation with periodontitis Objectives:  The reduction in the level of oestrogen, typical in menopause, has some effect on the health of the oral cavity. In fact, post-menopausal women present more severe periodontal disease than pre-menopausal women. Numerous factors can be held to be responsible for this increase, among which are the effects of oestrogens on the oral epithelium, on the salivary glands, on bone tissue and on the endothelium. Our double blind study aims to evaluate the possible variations in oral microcirculation in post-menopausal women. Methods:  Twenty-seven women in post-menopau…

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Multiple scerosis: oral manifestations and dental implications.

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RECENTLY DEVELOPED FOR DENTINAL ADHESIVES IN RESTORATIVE MATERIALS: MORPHOLOGICAL RESULTS

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Oral candidiasis and oral hyperplastic candidiasis: clinical presentation

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Burning Mouth Syndrome

ABSTRACT Background Burning mouth syndrome (BMS) is an atypical orofacial algesic syndrome. The aim of the authors' research was to investigate the morphological characteristics of peripheral blood circulation in patients with BMS in comparison with those of the peripheral blood circulation in healthy people. Methods The authors examined 28 subjects, of whom 14 (10 women and four men) had BMS and 14 (nine women and five men) were healthy control subjects. They performed videocapillaroscopic examination with a capillaroscope with a fiber-optic probe at a magnification of ×200, which allowed them to examine the morphological characteristics within the capillaroscopic area accurately. Results …

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PRELIMINARY STUDIES OF MICROCIRCULATORY IN SEPSI

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Oral diseases in a patient with Prader-Willy syndrome.

BACKGROUND: A case of Prader-Willi syndrome (PWS) in a 13-year-old girl is reported. The patient presents with systemic and oral manifestations of the disease. Case report The patient shows: obesity, hypotonia, mental retardation, small hands, prominent forehead, strabismus, hypoplastic teeth, poor oral hygiene, caries, oral candidiasis and thick, sticky saliva. This case is reported to underline the importance of the oral and dental problems of these patients. Caries and oral candidiasis are correlated with the reduced secretion of saliva and with poor oral hygiene. The role of paediatric dentistry is considered to be necessary for the prevention of oral complications of this syndrome.

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Capillaroscopic and histologic examination of the human labial mucosa: A new non invasive methodology compared with the histological exam

The aim of our study is to compare the capillaroscopic examination in vivo with the histological examination in vitro of labial microcirculation in healthy subjects. Methods. Twenty-nine subjects (19 females, 10 males; mean±SD age 55.61±2.55; range 45-65 years) were examined in our laboratory. The characteristics of labial microcirculation were examined using computerised videomicroscopic techniques and histological exam. Results. The results obtained with both methods showed some analogies: in fact, the differences in capillary diameter were in the range of ±0.3 µ; regarding capillary density as well, a variation of ±2 capillaries per mm2 was found. Comparing the results obtained with both…

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Ortodonzia estetica: vantaggi e limiti della tecnica Invisalign

Riassunto Obiettivi Lo scopo di questo lavoro e definire vantaggi e limiti della tecnica Invisalign rispetto a metodiche ortodontiche tradizionali. Materiali e metodi E stata condotta una revisione sistematica della letteratura attraverso l’uso di diversi database, come MedLine, PubMed, Scopus. La ricerca copre il periodo che intercorre tra il 2000 e il 2011. Altre fonti sono state selezionate dai riferimenti bibliografici citati nei lavori consultati. Risultati e conclusioni La ricerca scientifica ha portato negli anni allo sviluppo di soluzioni atte a soddisfare esigenze estetiche e funzionali, a partire dai bracket in ceramica e dalla tecnica linguale fino ad arrivare negli anni Novanta …

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A non-parametric segmentation methodology for oral videocapillaroscopic images

We aim to describe a new non-parametric methodology to support the clinician during the diagnostic process of oral videocapillaroscopy to evaluate peripheral microcirculation. Our methodology, mainly based on wavelet analysis and mathematical morphology to preprocess the images, segments them by minimizing the within-class luminosity variance of both capillaries and background. Experiments were carried out on a set of real microphotographs to validate this approach versus handmade segmentations provided by physicians. By using a leave-one-patient-out approach, we pointed out that our methodology is robust, according to precision-recall criteria (average precision and recall are equal to 0.9…

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Endodontic Microbiology: A Bibliometric Analysis of the Top 50 Classics

Background. Citation analysis has emerged to play a significant role in recognition of the most useful areas of research. Endodontic microbiology has been a topic of interest for endodontists as well as periodontists and oral surgeons. This bibliometric analysis is aimed at identifying and reporting the characteristics of the top 50 cited articles on endodontic microbiology. Methods. The articles were identified through a search on Web of Science (WoS), property of Clarivate Analytics database published on endodontic microbiology. The citation information of the selected articles was recorded. The Journal of Endodontics, International Endodontic Journal, Oral Surgery Oral Medicine Oral Path…

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PERIODONTAL MICROCIRCULATORY ABNORMALITIES IN PATIENTS WITH SYSTEMIC SCLEROSIS

BACKGROUND: The aim of this study was to observe the differences in periodontal microcirculation between healthy patients and patients with systemic sclerosis (SSc). METHODS: Fifteen healthy patients and 15 patients with SSc were examined. Periodontal capillaroscopy was used to investigate the characteristics of microcirculation. The visibility, course, tortuosity, possible presence of microhemorrhages, average caliber of the capillary loops, and number of visible capillary loops per square millimeter were evaluated for each patient. RESULTS: The investigation was simple, non-invasive, and repeatable for each patient. In patients with SSc, it was possible to observe a reduced number of capi…

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A rare case of neuroma of the tongue

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"In vivo" evaluation of the vascular pattern in oral peri-implant tissues.

Abstract Introduction The vascularisation of the peri-implant tissue represents the key factor in obtaining a successful result in implantology, since an adequate vascular supply allows wound healing and the presence of numerous growth factors that promote osteogenesis. The aim of this study was to analyse “in vivo” the vascular pattern of the peri-implant mucosa in subjects that received implant treatment. Materials and methods In the study 22 subjects were examined, 11 of whom (test group) received dental implants (Straumann Dental Implant System ® ) while 11 were in the control group; the analysis was performed in the peri-implant masticatory mucosa. The evaluation of the microcirculatio…

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ORAL MICROVASCULAR ABNORMALITIES IN PATIENTS WITH RHEUMATOID ARTHRITIS

Microvascular involvement represents one of the first apparent steps in many autoimmune diseases such as rheumatoid arthritis (RA). Early in the disease, peripheral microangiopathy may be easily recognized and studied by videocapillaroscopy. The aim of this study has been to observe the differences in labial microcirculation between healthy patients and patients suffering from RA. A total of 30 healthy patients and 30 patients suffering from RA were examined. The patients with conditions known to compromise microcirculation, such as diabetes, hypertension, or some pharmacological treatments were not included in the study. All the patients were non-smokers. Labial capillaroscopy was used to …

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Periodontal microcirculation in diabetics: An in vivo non-invasive analysis by means of videocapillaroscopy

Summary Background Diabetes mellitus is today considered a society-wide disease of a chronic/degenerative nature. Among the secondary effects of diabetes, the one that interests the dental surgeon most is diabetic parodontopathy. The aim of this study was to underline and objectify microcirculatory variations at a periodontal mucous level in type 2 diabetics. Material/Methods The study enrolled 80 subjects: 40 subjects with a diagnosis of diabetes mellitus type II (18 males and 22 females, between 44 and 85 years of age); and 40 healthy subjects (17 males and 23 females, between 44 and 78 years of age). All the subjects, both diabetic and healthy, were submitted to a videocapillaroscopic ex…

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ORAL MUCOSITIS

The standard treatment for malignant neoplasia of the cervicofacial area is surgery in association with radio- and/or chemotherapy. These therapies can cause local and systemic complications. Mucositis is the most common dosecorrelated complication to the oral cavity. It is particularly difficult to treat in patients who are already physically and psychologically exhausted by the tumoral pathology. This study illustrates, through a review of the literature, the attack rate, the pathogenesis and the clinical course of the mucositis, as well as the correct dental approach and clinical- therapeutic management of these patients, with the aim of improving the quality of their lives.

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Smoking Habit and Oral Health in Women

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MICROCIRCULATION AND SEPSIS

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La diagnosi precoce della sclerosi sistemica progressiva

BACKGROUND: The study considers the oro-facial manifestations occurring in a group of patients suffering from progressive systemic sclerosis, evaluating their predictive role and monitoring the systemic disease. METHODS: 34 patients with systemic sclerosis were examining: 30 women, 4 men, at the Department of Dental Sciences, Palermo University, from July 1998 to March 2001. All patients were positive for the diagnostic criteria of scleroderma.1 For each patient we considered: observation of any changes in soft tissues of the oral cavity; evaluation of possible xerostomia; evaluation of any fungal infections; presence of prosthetic sores in patients wearing dentures; DMFS evaluation; evalua…

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THE ELEVATION OF THE MAXILLARY SINUS. OUR CLINICAL EXPERIENCE. BULLETIN DU GROUPEMENT INTERNATIONAL POUR LA RECHERCHE SCIENTIFIQUE EN STOMATOLOGIE ET ODONTOLOGIE

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Comparison of Interactive Teaching in Online and Offline Platforms among Dental Undergraduates

In recent years, the educational system has focused more on the holistic development of an individual. Modern technology has changed the educational environment to provide students with better academic opportunities. Along with the education system, teaching techniques and learning tools have also changed with digital evolution. This research was undertaken to assess the academic performance of interactive teaching methods in offline and online platforms in Periodontics among BDS undergraduates at a dental college in India. This prospective study was conducted among 49 students: Group I (n = 24, online class through Zoom) and Group II (n = 25, offline classes). The subject was divided into …

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Appraisal and promotion of the oral health in a group of visually impaired patients.

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The effect of acupuncture on oral microcirculation in healthy volunteers: an exploratory study.

Background Acupuncture is a therapeutic technique currently used in the treatment of many pathologies. The aim of this study is to evaluate the potential effect of acupuncture on “in vivo” variations in oral microcirculation in healthy subjects. Methods An exploratory study was conducted on 40 healthy subjects: 20 cases (mean 55.90, SD 16.04) and 20 controls (mean 51, SD 11.91). Videocapillaroscopy was used to detect variations in oral microcirculation. This method permits an accurate and non-invasive in vivo study of the capillaries of the oral mucous. The site selected for this pilot study is the lower lip since it is the simplest to investigate and is more readily accessible. Assessments…

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PRELIMINARY OBSERVATIONS ABOUT CAPILLAROSCOPIC AND HISTOLOGIC EXAMINATIONS OF THE HUMAN LABIAL MUCOSA. SURGICAL RADIOLOGIC ANATOMY

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Sistematica terapeutica delle infezioni micotiche del cavo orale

Obiettivi. Effettuare una revisione sistematica sui farmaci disponibili per il trattamento della candidosi orale in modo da scegliere la terapia più adeguata. Materiali e metodi. La candidosi orale rappresenta una causa sempre più frequente di infezione che può in taluni casi compromettere la qualità della vita del paziente. L’alta incidenza della candidosi orale può essere correlata con una molteplicità di fattori predisponenti che favoriscono la conversione della Candida da commensale a parassita. Alcuni fattori che contribuiscono a questo incremento sono rappresentati dai trattamenti antibiotici ad ampio spettro, dalla terapia con glucocorticoidi, dall’aumento dei pazienti severamente im…

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Viability and integrity of cell present in particulate bone collected during the preparation of the implant site: a preliminary study

Aim: The aim of this study was to evaluate viability and integrity of cells (Osteoblasts and Osteocytes) present in the particulate bone (Bone Chips), obtained during the preparation of the implant site. Methods: Four patients aged between the IV and the VI decade presenting edentulous areas class III of Cawood and Howell were selected. All patients suffering from systemic and oral diseases and smoking were excluded. The surgeries were performed with the conventional technique, full-thickness flap, and the implant sites were prepared with large coils calibrated burs mounted on surgical micromotor at a speed of 600 rpm and external irrigation of saline solution previously cooled . The partic…

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Evaluation of Cyclic Fatigue of Hyflex EDM, Twisted Files, and ProTaper Gold Manufactured with Different Processes: An In Vitro Study.

Introduction. The main aims of root canal instrumentation are to provide an environment that will lead to healing and to provide a root canal shape that is comfortable to clean and seal. When working with rotary endodontic instruments, the most significant concerns are that the instrument might fracture in the root canal, thus affecting the treatment outcome. Hence, it is of immense importance to know which file systems have more cyclic fatigue resistance. Methodology. This study evaluated the effect of the curved segment length of the artificial canal (the arch), and the number of cycles necessary in fracture of Hyflex EDM, Twisted files, and ProTaper Gold were recorded. Sixty NiTi rotary …

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Evaluation of the clinical and histological effectiveness of isoretinoin in the therapy of oral leukoplakia. Ten years of experience: is management still up-to-date and effective?

Various studies have evaluated the therapeutic effectiveness of vitamin A derivatives in the treatment of oral leukoplakia (OL). Not all the studies have shown concordant results. The aim of our study, which has a 10-year follow-up, was to test the effectiveness of topical therapy based on 0.18% isotretinoin by comparing it with that most frequently used, i.e., at 0.05% concentration. Forty patients with an established diagnosis of OL were involved in the study. The patients were randomly divided into two groups and the drug was administered topically at 0.05% and 0.18% concentrations. The drug was applied twice a day for 3 consecutive months; then it was suspended for 1 month, and the biop…

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Periodontal disease and sjogren syndrome: a possible correlation?

Sjögren syndrome (SS) is a chronic autoimmune rheumatic disease characterized by a progressive lymphocytic infiltration of exocrine glands, especially salivary and lachrymal ones, leading to xerostomia, parotid gland enlargement, and xerophthalmia. The aim of this study is to describe the capillaroscopic pattern of the interdental papilla in patients with SS and to evaluate a possible correlation with periodontal disease. Methods: A total of 25 patients affected by SS and 25 healthy controls were examined. The patients with conditions that compromise microcirculation, such as diabetes, hypertension, hyperlipidemia, or some pharmacological treatments, were not included in the study. All the…

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Changes of oral microcirculation in chemotherapy patients: A possible correlation with mucositis?

The aim of this investigation is to appraise labial oral microcirculation in chemotherapy patients to clarify the effects of cytotoxic agents on oral microvessels. Twenty-five patients with diagnosis of head and neck tumors were recruited in the study. All the patients were submitted to chemotherapy. Labial oral microcirculation was evaluated on labial mucosa using oral videocapillaroscopy. The statistical significance was checked with the Mann-Whitney U-test (P < 0.05). The analysis of videocapillaroscopic patterns showed statistically significant variations relative to the diameter of the incoming loop; the diameter of the outgoing loop; and loop tortuosity. This study shows that capillar…

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Filter Masks during the Second Phase of SARS-CoV-2: Study on Population

During the SARS-CoV-2 pandemic, the most common countermeasure are the use of masks, which are supposed to filter inhaled and exhaled air to reduce the spread of the virus. The masks, which are medical devices, must be used by providing appropriate instructions for correct use. This study, which examined the population during the advanced stage of the pandemic, highlighted a substantial improvement in the management and choice of masks, even though the information disseminated to the population probably should be even more detailed and precise in order to avoid incorrect behavior that could compromise the effectiveness of these devices; in fact a high percentage of subjects had behaviors th…

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Investigating the Antioxidant and Cytocompatibility of Mimusops elengi Linn Extract over Human Gingival Fibroblast Cells

Background—chlorhexidine (CHX) is most commonly used as a chemical plaque control agent. Nevertheless, its adverse effects, including teeth discoloration, taste alteration and calculus build-up, limit its use and divert us to medicinal herbs. The purpose of the study was to evaluate the phytochemical composition, antioxidant potential, and cytotoxic effects of Mimusops elengi Linn extract (ME) over normal human cultured adult gingival fibroblasts (HGFs). Methods—in vitro phytochemical screening, total flavonoid content, antioxidant potential by DPPH and Nitric Oxide (NO) radical scavenging activity, and cytotoxic effects of ME extracts over HGF were explored. The viability of HGF cells was …

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RECENTLY DEVELOPED FOR DENTINAL ADHESIVES IN RESTORATIVE MATERIALS

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Valutazioni cliniche e strumentali di fratture di impianti dentali

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Good oral health and diet.

An unhealthy diet has been implicated as risk factors for several chronic diseases that are known to be associated with oral diseases. Studies investigating the relationship between oral diseases and diet are limited. Therefore, this study was conducted to describe the relationship between healthy eating habits and oral health status. The dentistry has an important role in the diagnosis of oral diseases correlated with diet. Consistent nutrition guidelines are essential to improve health. A poor diet was significantly associated with increased odds of oral disease. Dietary advice for the prevention of oral diseases has to be a part of routine patient education practices. Inconsistencies in …

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Musicisti e dolore cranio-facciale

LETTER TO EDITOR

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Risk of Periodontal Disease: Is there a Correlation with the Type of Antihypertensive Medication?

Introduction: The purpose of this study was to evaluate the effects of long-term oral antihypertensive treatment using centrally acting sympatho-inhibitory drugs (clonidine) and beta-blockers (metoprolol) on capillary microcirculation in the labial and periodontal mucosa.&#x0D; Methods: Sixty subjects were recruited for the study: 20 patients affected by hypertension in treatment with centrally-acting sympatho-inhibitory drugs (64.28 ± 11.78 years); 20 patients in treatment with beta-blockers (62.03 ± 9.84 years) and 20 healthy subjects (62.06 ± 6.72 years). We use the videocapillaroscopic technique to evaluate in vivo the microcirculation of the labial mucosa corresponding to the lower lip…

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Evaluation of the Oral Microcirculation in Patients Undergoing Anti COVID-19 Vaccination: A Preliminary Study

Videocapillaroscopy allows the study of both the morphological and architectural structure of the microcirculation and its hemodynamic conditions; these parameters are directly involved in autoimmune and/or inflammatory pathologies. The purpose of this research, based on capillaroscopy, is to establish whether a patient who receives an anti-COVID 19 vaccine has any changes in their oral microcirculation. A complete capillaroscopic mapping of the oral cavity of the subjects examined was made; the investigated mucosa sites were the following: cheek, labial, chewing-gingival and back of the tongue. This study showed an increase in capillary density from the comparison between the mean labial c…

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Association of Vital Pulp Therapy Outcomes with Tooth Type, Arch Location, Treatment Type, and Number of Surfaces Destroyed in Deciduous Teeth: A Retrospective Study

There is a paucity of information concerning vital pulp treatment outcomes in the undergraduate teaching setting. This study aimed to determine which type of deciduous molar, arch location, type of vital pulp therapy, and the number of carious surfaces involved had a better prognosis when carried out by undergraduate dental students. The method used was the review of clinical records of 590 patients with 600 deciduous molars, that visited the outpatient undergraduate dental clinics for vital pulp therapy. Statistical analysis used to determine the associations of tooth type, arch location, treatment type, and the number of carious surfaces involved in successful outcomes was logistic regres…

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Effects of a nonsurgical exercise program on the decreased mouth opening in patients with systemic scleroderma.

The decreased mouth opening (microstomia) represents a frequent finding in patients with systemic scleroderma (SSD), but little information is available about the efficacy of nonsurgical management of this condition. The aim of this study is to assess the effects of a nonsurgical exercise program on the decreased mouth opening in a group of 10 SSD patients with severe microstomia (maximal mouth opening 0.1). At the end of the 18-week period, all patients commented that eating, speaking and oral hygiene measures were easier. The edentulous subjects also experienced less difficulty inserting their own dentures. These findings suggest that regular application of the proposed exercise program m…

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Videocapillaroscopy of the Oral Mucosa in Patients with Diabetic Foot: Possible Diagnostic Role of Microangiopathic Damage?

Introduction: Diabetic foot represents one of the most serious and expensive complications of diabetes and is subject to a high percentage of amputations that are almost always preceded by ulcers ascribable to neuropathy and/or vasculopathy. Videocapillaroscopy (VCS) can be a valuable aid in order to uncover morpho-structural anomalies in the vascular bed, both at the level of the oral mucosa and at the level of the terminal vessels of the lower limb. Materials and methods: Sixty subjects divided into 4 groups were enrolled: 15 healthy subjects; 15 patients with diabetes for more than 10 years without ulcerative foot lesions; 15 patients with neuropathic diabetic foot (clinical diagnosis, M…

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In vivo evaluation of periodontal microcirculatory changes associated with endodontic treatment.

The purpose of this study was to investigate in vivo the gingival microcirculatory changes associated with endodontic treatment using the continuous wave of condensation technique. MATERIALS AND METHODS: Twenty necrotic one canal roots of 20 cooperative patients of both sexes, aged between 20 and 43 years, were selected. All patients were examined by capillaroscopy before, immediately after endodontic treatment, and after 7 days. The last examination was carried out by the same operator, and repeated twice for each examined area: masticatory, buccal and labial mucosa corresponding to the endodontically treated root. All canals were prepared using a simultaneous technique with Ni-Ti files (M…

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CAPSAICIN STIMULATION AND NEUROGENIC EXPERIMENTALLY INDUCEND INFLAMMATION OF THE HUMAN LABIAL MUCOSA

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Vascolarization of Peri-Implant Tisues:Literature Review

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Angiogenesis of oral lichen planus: a possible pathogenetic mechanism.

Objective: Oral Lichen Planus (OLP) is a chronic inflammatory disease with an autoimmune inflammatory pathogenesis. The aim of the research is to compare the vascular endothelial growth factor (VEGF) and adhesion of molecules in the biopsy samples of patients affected by OLP, in order to research the presence of the angiogenetic phenomenon and to understand its pathogenetic mechanism. Materials and Methods: Thirty OLP patients and thirty healthy subjects were enrolled in a study. The immunohistochemical analysis of the VEGF and vascularendothelial adhesion molecules was carried out by means of primary antibodies and anti-CD34, anti-VEGF, antiCD106 antigen (VCAM-1) and anti-CD54 antigen (ICA…

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PRELIMINARY TREATMENT ABOUT MODIFICATION OF THE MORPHOLOGY OF THE THEETH DURING ORTHODONTIC TREATMENT

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Root and Root Canal Configuration Characterization Using Microcomputed Tomography: A Systematic Review

This systematic review&rsquo;s objective was to conduct a complete analysis of the literature on the root canal morphology using advanced micro-computed tomography. The electronic web databases PubMed, Scopus, and Cochrane were examined for research papers concerning the chosen keywords, evaluating the root canal morphology using Micro-CT, published up to 2021. The articles were searched using MeSH keywords and searched digitally on four specialty journal websites. DARE2 extended (Database of Attributes of Reviews of Effects) was used to assess bias risk. The information was gathered from 18 published studies that strictly met the criteria for inclusion. In the included studies, a total of …

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Introduction of a system for choosing and placing the anterior teeth of complete dentures.

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Rapid palatal expansion: the role of microcirculation

Transverse palate modifications fall under expansive orthopedic therapy of the upper maxilla. The only practical approach to the problem on the transverse plane is that of performing the expansion of the maxillary arch through an opening of the median palatal suture. It is important to understand the changes of the vascular network in midpalatal suture following the starting of rapid maxillary expansion. It is critical to maintain the blood supply and circulation for the osteogenesis and bone remodeling after the expansion. The aim of this research was to evaluate the effects of rapid orthopedic expansion (REP) at the microcirculatory level through capillaroscopic examination. METHODS: Fift…

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Flow evaluation of red blood cells in capillaroscopic videos

We aim at describing a non-parametric approach to evaluate blood cells velocity in oral capillascopic videos. The proposed methodology is based on the application of standard optical flow algorithms and it is part of a general environment to support during the diagnostic process for evaluating peripheral microcirculation in real time. We validated our approach versus handmade measurements provided by physicians. Results on real data pointed out that our system returns an output coherent to these latter observations.

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PRELIMINARY TREATMENT ABOUT MODOFICATION OF THE MORPHOLOGY OF THE TEETH DURING ORTHODONTIC TREATMENT

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Oral manifestation of Kawasaki disease

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CEFACLOR INDUCED PEMPHIGUS VULGARIS

Pemphigus is a chronic disease with an outcome that is not without risk. It is characterised by loss of the intraepithelial cell-cell relationship (acantholysis). Underlying the disease is an autoimmune disorder in which the desmosomes are damaged by antibodies directed against particular molecules called desmogleins (particularly 3 and 1). Various types of pemphigus have been described with different antibody profiles and clinical signs. In the present paper, a case of pemphigus vulgaris associated with the medication cefaclor monohydrate is reported. Histological and immunological evaluation of the biopsy sample led to a diagnosis of pemphigus vulgaris. The patient, who was not hospitalis…

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Permanence of Modifications in Oral Microcirculation in Ex-Smokers.

Background: The aim of this study was to assess the long-term effects of smoking and to investigate the permanence of this damage to the oral microcirculation. Material/Methods: We recruited 75 patients and divided them into 3 groups: group 1 was composed of 25 healthy non-smokers, group 2 was composed of 25 healthy current smokers, and group 3 was composed of 25 healthy ex-smokers. Video-capillaroscopic examination was performed on all patients. The video-capillaroscopic investigation was performed on patients in sitting position, always with the same light source, at the same room temperature (23°C), in the morning, with the same operator (GAS), and was repeated many times for every area …

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PANORAMIC PERIODONTAL CAPILLAROSCOPY: A NEW DIAGNOSTIC METHOD. ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY

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Oral necrotizing microvasculitis in a patient affected by Kawasaki disease

Kawasaki disease (KD) was first described in 1967 by Kawasaki, who defined it as ?mucocutaneous lymph node syndrome?. KD is an acute systemic vasculitis, which mainly involves medium calibre arteries; its origin is unknown, and it is observed in children under the age of 5, especially in their third year. The principal presentations of KD include fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy. Within KD, oral mucositis ? represented by diffuse mucous membrane erythema, lip and tongue reddening and lingual papillae hypertrophy with subsequent development of strawberry tongue ? can occur both i…

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PEMPHIGUS VULGARIS IN A MEDITERRANEAN YOUNG ADULT MANIFESTING AS DESQUAMATIVE GINGIVITIS

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ETIOPATOGENESI DEL DOLORE MAXILLO-FACCIALE = Le possibili cause di dolore del distretto oro-facciale

Oral tissue damage and mucositis pain can be a significant problem for patients. The frequency and severity of these problems can vary significantly from patient to patient. Oral complications primarily are associated with discomfort and interference with oral function. Oral tissue damage and pain can result from a number of different processes. There are many types of pain and many locations to get pain. The body uses pain to tell the brain that something is wrong. Never ignore pain. Any type of pain symptom needs prompt professional medical advice for diagnosis of the underlying cause of the pain.

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INFIAMMAZIONE NEURO-MEDIATA E PATOLOGIE DELLA MUCOSA LINGUALE: UN'IPOTESI EZIOPATOGENETICA

The nervous system contributes to the pathophysiology of peripheral inflammation and a neurogenic component has been implicated in many inflammatory disease, including oral diseases. Neurogenic inflammation should be regarded as a protective mechanism wich forms the first line of defense and protects tissue integrity. However, prolonged noxius stimulation may result in the inflammatory response. This review focuses on the evidence suggesting that neuropeptides have a pivotal role in the complex cascade of chemical activity associated with oral diseases. The pathophysiology is complex and neuropeptides are not solely responsible for the initiation and progression of the disease. However, sin…

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Mantenimento della salute orale nei pazienti non vedenti: valutazione dell'efficacia dei programmi di istruzione

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Il moderno approccio alla diagnostica radiografica per immagini in odontoiatria

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Oral microcirculation observed in vivo by videocapillaroscopy: a review

Capillaroscopy is a non-invasive diagnostic technique that is fundamental in viewing peripheral circulation and in studying microangiopathies. The morphological study of microcirculat ion is of fundamental importance, mainly because the microvascular bed is directly involved in the etiopathogenesis of autoimmune disorders and acute and chronic inflammatory pathological conditions. The value of capillaroscopic investigation as a diagnostic means in cases of peripheral microcirculation disorders has been confirmed by numerous studies. Other studies used capillaroscopic investigations to evaluate microcirculation damage not as a complication of disease (diabetes), but as its initial stage, and…

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Anatomical evaluation of oral microcirculation: capillary characteristics associated with sex or age group.

Abstract Background There are various types of oral mucosa specific to different parts of the mouth and each of these has a unique histological structure. The variations in the epithelial structure are consistently related to observable differences in the underlying microcirculation: i.e. differences in the course, conformation, and density of capillaries. The aim of this research has been to investigate oral microcirculatory differences between men and women as well as between various age groups, in order to map the oral mucosa, and to highlight changes occurring during aging. Methods A total of 45 healthy subjects were enrolled for this study (12 men and 33 women; mean age 60.37; range 30…

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Burning mouth syndrome: is acupuncture a therapeutic possibility?

Burning mouth syndrome is a chronic pathology of unknown ethiopathogenesis. The aim of this study was to evaluate whether acupuncture can produce a reduction of the burning sensation by influencing the oral microcirculation. METHODS: Thirty patients (10 male and 20 female; mean age +/- SD = 65.4 +/- 2.17) and 30 healthy subjects (10 male and 20 female; mean age +/- SD = 62.06 +/- 6.72) were recruited for the study. The patients were treated with acupunctural techniques based on traditional Chinese medicine. Microcirculation was observed in vivo using videocapillaroscopy at three different times: t(0)) in the absence of acupuncture; t(1)) 1 minute after the insertion of the needles; and t(2)…

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An In Vitro Stereomicroscopic Evaluation of Bioactivity between Neo MTA Plus, Pro Root MTA, BIODENTINE &amp; Glass Ionomer Cement Using Dye Penetration Method

The ideal root end filling material should form a tight seal in the root canal by adhering to the cavity walls. Several materials have been used for root end filling. The present study aims to find out and compare the bioactivity of Neo MTA Plus, Pro Root MTA White, BIODENTINE &amp; glass ionomer cement as root end filling materials using 1% methylene blue as tracer. Materials and methods: 80 extracted human permanent maxillary anterior teeth were used in the study. They were divided into four groups. Specimens were sectioned transversely in the cervical area to separate the crown from the root. The root canal was obturated with gutta percha and zinc oxide eugenol sealers. Thereafter, each …

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Risk perception of sars-cov-2 infection and implementation of various protective measures by dentists across various countries

Objective: Healthcare workers in general are at a high risk of potential infections with COVID-19, especially those who work with aerosol generating procedures. Dentists fall in this category, as not only do they operate with aerosol generating procedures but also operate within a face-to-face contact area. Methods: A structured self-administered questionnaire was developed at Najran University and provided to the participants for data collection. The data collected included information on risk perception and incorporation of measures for protection against COVID-19 to gauge the attitude of dentists during this period. Also, clinical implementation of various protective measures was reviewe…

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Erratum to “Anatomical evaluation of oral microcirculation: Capillary characteristics associated with sex or age group” [Ann. Anat. 191(4) (2009) 371–378]

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Evaluation of the serum levels of retinol in patients affected by leukoplakia and oral lichen planus: a statistical analysis.

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VASCULARIZATION OF PERI IMPLANT TISSUES: LITERATURE REVIEW

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Role of Natural Cross Linkers in Resin–Dentin Bond Durability: A Systematic Review and Meta-Analysis

Background: The role of endogenous Matrix Metallo Proteinases in resin dentin bond deterioration over time has been well documented. The present study aimed to systematically review the literature; in vitro and ex vivo studies that assessed the outcomes of natural cross-linkers for immediate and long-term tensile bond strength were included. Methods: The manuscript search was carried out in six electronic databases—PubMed/MEDLINE, LILACS, SciELO, Cochrane, Web of Science and DOAJ, without publication year limits. Only manuscripts in English (including the translated articles) were selected, and the last search was performed in December 2020. The Preferred Reporting Items for Systematic Revi…

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Alternative Methods of Sterilization in Dental Practices Against COVID-19

SARS-CoV-2, and several other microorganisms, may be present in nasopharyngeal and salivary secretions in patients treated in dental practices, so an appropriate clinical behavior is required in order to avoid the dangerous spread of infections. COVID-19 could also be spread when patients touches a contaminated surface with infected droplets and then touch their nose, mouth, or eyes. It is time to consider a dental practice quite similar to a hospital surgery room, where particular attention should be addressed to problems related to the spreading of infections due to air and surface contamination. The effectiveness of conventional cleaning and disinfection procedures may be limited by seve…

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Lesione ulcerativa della mucosa orale: diagnosi di un caso clinico.

Le stomatopatie possono avere manifestazioni cliniche differenziabili, ma in alcuni casi sono sovrapponibili. In quest’ultima evenienza la diagnostica differenziale ha un ruolo di primo piano al fine di giungere ad una corretta diagnosi e quindi ad un corretto management terapeutico. Da questo punto di vista le classificazioni delle stomatopatie devono consentire un percorso diagnostico razionale. I metodi classificativi non vanno considerati come meri elenchi ma devono consentire ai clinici un linguaggio comune ed un algoritmo diagnostico ragionato e quindi corretto. Gli autori presentano un suggestivo caso clinico di lesione ulcerativa della mucosa orale che a prima impressione poteva ind…

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CANALAR REPROCESSING WITH NI-TI INSTRUMENTS: OUR EXPERIENCE ITALIAN JOURNAL OF ANATOMY AND EMBRIOLOGY

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A randomized trial assessing the effectiveness of different concentrations of isotretinoin in the management of lichen planus

The aim of our 10-year study was to test the effectiveness of topical therapy based on 0. 18% isotretinoin, comparing it with that most frequently used, i.e. at 0.05% concentration. Seventy patients with an established diagnosis of oral lichen planus were involved in the study. The patients were randomly divided into two groups, and the drug was administered topically at 0.05% and 0. 18% concentrations. The drug at the higher concentration, according to the same protocol, was administered to the patients who did not benefit from the therapy at the lower concentration. None of the cases of reticular lichen planus showed clinical or histological improvement. In contrast, the atrophic-erosive …

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L'ESAME CAPILLAROSCOPICO ORALE: NUOVA METODICA DIAGNOSTICA

The morphological-functional study of microcirculation is of fundamental importance; in fact, the microvascular bed is directly involved both in autoimmune etiopathogenesis pathologies, and in acute and chronic inflammatory etiopathogenesis pathologies. Oral capillaroscopy is a very stimulating method for studying microcirculation, because of the possibility of studying small vessels in vivo by means of a microscope. Today, it is becoming more reliable thanks to the improvement of the observation tools (photography, videomicroscopy).

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Oral capillaroscopy: our experience

Capillaroscopy has now definitely become an important and indispensable exam in the area of diagnosing vasculopathies and in particular micro angiopathies. The type of damages connected to these anatomy pathologies regarding the actual micro vascular unit work in a functional pathogenic of an extreme importance, in conditioning the course and the eventual aggravation of micro angiopathies properly called vasculity and also of macro angiopaties. In all, this underlines the great importance achieved by using certain instrumental exams which complements the clinical research, exactly because of the valid elements which have been given for a complete and precise morphological valuation for the …

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The Use of Hall's Technique Preformed Metal Crown (HTPMC) by Pediatric Dentists in Malaysia

Introduction. Hall’s technique preformed metal crown (HTPMC) has been used widely by pediatric dentists in developed countries as a new approach for managing decayed primary molars without local anesthesia, caries removal, and tooth preparation. Currently, inadequate information is available regarding the implementation of this technique (HTPMC) in Malaysia. This study is aimed at evaluating the implementation of HTPMC by Malaysia’s pediatric dentists and identify the co-occurrence frequencies of the HTPMC implementation with the respondents’ demographic profile. Materials and Methods. A cross-sectional questionnaire-based research was conducted among 65 pediatric dentists in Malaysia. Onli…

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Microcirculation in the healing of surgical wounds in the oral cavity.

Abstract. The aim of this research is to evaluate in vivo the characteristics of microcirculation after taking a biopsy sample from the oral mucosa. 20 patients were recruited to the study and all underwent an oral mucosa biopsy for the excision of benign neoformations. The modifications in the oral microcirculation were evaluated in vivo in correspondence to the surgical site through videocapillaroscopy at three different times: 30 min before the biopsy; 48 h after the biopsy; and 7 days after the biopsy. The statistical significance was checked with the Mann–Whitney U-test (P < 0.05). The analysis of videocapillaroscopic patterns showed statistically significant variations relative to the…

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La guarigione della ferita chirurgica nel cavo orale

OBJECTIVES The aim of the study is to describe the physiological mechanism of healing of the surgical wound of the oral cavity and to present the systemic and local factors that can influence it. MATERIALS AND METHODS Hemostasis starts with the activation of the platelets and the coagulation cascade which carry out the vascular constriction and the formation of the fibrin clot which stops the blood loss and provides a temporary scaffold for the migration and anchoring of the cells that will reach the subsequent stages. The clot and surrounding injured tissue begin to release pro-inflammatory cytokines and growth factors such as tranforming growth factor-β (TGF-β), platelet-derived growth fa…

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APPRAISAL AND PROMATION OF THE ORAL HEALTH IN A GROUP OF VISUALLY IMPAIRED PATIENTS

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Transverse Asymmetries of the Maxilla Even in Healthy and Apparently Symmetrical Subjects

In the formulation of an orthodontic treatment plan, the three-dimensional analysis of the dental arches represents a fundamental moment for the evaluation of all the morphological parameters necessary in order to have a correct and complete diagnosis. In this regard, the study of the dental arches on the horizontal plane is sometimes neglected or not thorough enough. When evaluating the transverse dimensions of the dental upper arche, the presence of an asymmetry is frequently found, and it means that an hemiarch is larger than the other. Furthermore, any variation in one of the three planes of space always involves an alteration also on the other two planes in order to have compensation. …

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FRATTURA DI IMPIANTI DENTARI. CASO CLINICO

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The SARS-CoV-2 Antibodies, Their Diagnostic Utility, and Their Potential for Vaccine Development.

Antibodies (Abs) are important immune mediators and powerful diagnostic markers in a wide range of infectious diseases. Understanding the humoral immunity or the development of effective antibodies against SARS-CoV-2 is a prerequisite for limiting disease burden in the community and aids in the development of new diagnostic, therapeutic, and vaccination options. Accordingly, the role of antiviral antibodies in the resistance to and diagnosis of SARS-CoV-2 infection was explored. Antibody testing showed the potential in adding important diagnostic value to the routine diagnosis and clinical management of COVID-19. They could also play a critical role in COVID-19 surveillance, allowing for a …

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Patologie della mucosa orale

Un contributo innovativo allo studio di una disciplina odontoiatrica in continua evoluzione. L’obiettivo è quello di fornire al lettore, sia esso studente o professionista, una guida chiara del management diagnostico e terapeutico di patologie spesso multidisciplinari o sulle quali verte il rischio di trasformazione neoplastica. Frutto di anni di esperienza clinica, il testo intende dare un apporto alla formazione di un odontoiatra e di un medico attento e consapevole, ed erudire chiunque si accosti all’avvincente e complesso campo delle patologie della mucosa orale. Pietro Messina è professore ordinario dell’Università degli Studi di Palermo. Le discipline mediche di suo principale interes…

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MICROCIRCULATORY ABNORMALITY QUANTIFICATION IN PATIENTS WITH SYSTEMIC SCLEROSIS USING LABIAL VIDEOCAPILLAROSCOPY

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Burning mouth syndrome: An evaluation of in vivo microcirculation

Background. Burning mouth syndrome (BMS) is an atypical orofacial algesic syndrome. The aim of the authors’ research was to investigate the morphological characteristics of peripheral blood circulation in patients with BMS in comparison with those of the peripheral blood circulation in healthy people. Methods. The authors examined 28 subjects, of whom 14 (10 women and four men) had BMS and 14 (nine women and five men) were healthy control subjects. They performed videocapillaroscopic examination with a capillaroscope with a fiber-optic probe at a magnification of ×200, which allowed them to examine the morphological characteristics within the capillaroscopic area accurately. Results. The ca…

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OSTEONECROSIS OF THE JAW: AN UNUSUAL CASE REPORT

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Study of microcirculation in oral lichen planus by video-capillaroscopy.

Objective The aim of this study was to evaluate “in vivo” the oral microcirculatory characteristics in patients with oral lichen planus (OLP) and to discover any differences in microcirculation in comparison with healthy patients. Study design Twenty patients with established diagnosis of OLP and 20 healthy patients were examined in our laboratory by means of contact optical probe videocapillaroscopy. The examined areas for each patient were the right and the left buccal mucosae. Capillary density and total capillary diameter, as well as afferent and efferent loop diameter were studied; the discovery of characteristic (tortuous, branched) loops was also investigated. Results The results wer…

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Modifications of interdental papilla microcirculation: A possible cause of periodontal disease in Hashimoto's thyroiditis?

Summary Background Hypothyroidism is defined by a decrease in thyroid hormone production and thyroid gland function. The aim of the present research has been to evaluate the morphologic interdental papilla microcirculation of patients suffering from Hashimoto thyroiditis (HT) and to evaluate a possible correlation with the associated periodontal disease. Methods Fifteen healthy subjects and 15 patients suffering from HT were examined. The patients who showed conditions known to compromise microcirculation, such as diabetes, hypertension and pharmacological treatments, were not included in the group of healthy patients. All patients were non-smokers. Gingival capillaroscopy was used to inves…

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VASIDILATATION OF HUMAN GINGIVA AND NEUROGENIC INFLAMMATION

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Plywood Jig—A New Technique for Root Canal Curvature Measurement

The successful outcome of endodontic treatment is dependent on complete cleaning, shaping as well as three dimensional obturation of the root canal system. A conventional radiograph is a two-dimensional replication of a three-dimensional object and does not provide any conclusive evidence for canal curvatures. An accurate knowledge of the tooth anatomy and curvature is essential to avoid procedural errors. 100 freshly extracted human teeth were used in this study. Digital images were obtained using the plywood JIG and Schneider’s technique. These images were analyzed using the VixWin Pro digital image analyzing software (Gendex system). Statistical analysis was done using paired t test. The…

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INDAGINE VIDEOCAPILLAROSCOPICA: APPLICAZIONI IN MEDICINA ORALE

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MACROLIDES ANTIBIOTICS IN ODONTOSTOMATOLOGICAL PRACTICE:PAST. PRESENT AND FUTURE

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Dentinal microcracks after root canal instrumentation using instruments manufactured with different NiTi alloys and the SAF system: A systematic review

Aim: The aim of this systematic analysis was to assess the prevalence of dentinal microcracks at various levels (3, 6, and 9 mm from the apex) after using instruments made with conventional, R-Phase, and M-Wire NiTi alloys and the SAF system. Materials and Methods: Electronic searches were conducted in the databases Embase, Cochrane Library, Scopus, PubMed, and Web of Science. To arrange search methods, “MeSH” terms and/or keywords typically associated with the subject were paired with the Boolean operators “AND” and “OR.” Additional searches were conducted on the websites of four separate endodontic journals. After reading the titles and excluding duplicates, 1000 of the 1343 documents ori…

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VALUTAZIONI CLINICHE E STRUMENTALI DI FRATTURE DI IMPIANTI DENTALI: PRESENTAZIONE DI UN CASO CLINICO

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EFFECTS OF A FERRIC OXALATE DENTIN DESENSITIZER: SEM ANALYSIS

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