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RESEARCH PRODUCT
Photo-acoustic excitation and optical detection of fundamental flexural guided wave in coated bone phantoms.
Vantte KilappaJalmari PirhonenPetro MoilanenTimo KarppinenJussi TimonenZuomin ZhaoZuomin ZhaoPasi KarppinenRisto MyllyläEdward Hæggströmsubject
Materials scienceAcoustics and UltrasonicsBiophysics02 engineering and technology01 natural sciencesSensitivity and SpecificityImaging phantomBone and Bones010309 opticsOpticsLamb wavesFlexural strengthCoated Materials BiocompatibleBone Density0103 physical sciencesmedicineHumansRadiology Nuclear Medicine and imagingGuided wave testingRadiological and Ultrasound Technologyta114business.industryPhantoms ImagingLasersUltrasoundReproducibility of ResultsEquipment Design021001 nanoscience & nanotechnologyEquipment Failure Analysismedicine.anatomical_structureSoundAcoustic StimulationElasticity Imaging TechniquesUltrasonic sensorCortical bonePhase velocity0210 nano-technologybusinessPhotic StimulationDensitometrydescription
Abstract Photo-acoustic (PA) imaging was combined with skeletal quantitative ultrasound (QUS) for assessment of human long bones. This approach permitted low-frequency excitation and detection of ultrasound so as to efficiently receive the thickness-sensitive fundamental flexural guided wave (FFGW) through a coating of soft tissue. The method was tested on seven axisymmetric bone phantoms, whose 1- to 5-mm wall thickness and 16-mm diameter mimicked those of the human radius. Phantoms were made of a composite material and coated with a 2.5- to 7.5-mm layer of soft material that mimicked soft tissue. Ultrasound was excited with a pulsed Nd:YAG laser at 1064-nm wavelength and received on the same side of the coated phantom with a heterodyne interferometer. The FFGW was detected at 30-kHz frequency. Fitting the FFGW phase velocity by the F LC (1,1) tube mode provided an accurate (9.5 ± 4.0%) wall thickness estimate. Ultrasonic in vivo characterization of cortical bone thickness may thus become possible.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-02-20 | Ultrasound in medicinebiology |