Subcellular localization and characterization of nitric oxide synthase(s) in endothelial cells: physiological implications.

1994

Endothelial cells (EC) contain a constitutive Ca2+/calmodulin-dependent nitric oxide (NO) synthase (cNOS) which plays an important role in the local control of vascular tone. We compared the subcellular distribution of this enzyme in cultured and freshly isolated pig EC by determination of specific cNOS activity and immunoblot analysis. Similar studies were also performed with cultured and freshly isolated bovine and cultured human EC. Enzyme activity was predominantly (> 70%) associated with the particulate fraction of all EC types tested and was highest in freshly isolated porcine EC. Both specific cNOS activity and immunoreactivity were substantially higher (> 3-fold) in th…

Work and Organisational Psychology in Spain

1994

Cet article offre un panorama des recents developpements et des perspectives futures de la Psychologie du Travail et des Organisations comme discipline scientifique et comme profession en Espagne. Ces developpements ont pris place dans un contexte de changements sociopolitique et economique. Le cadre historique de la Psychologie du Travail et des Organisations en Espagne est brievement presente. Les recents developpements de la formation, des diplomes et des roles professionnels dans cette discipline sont egalement decrits. Une attention speciale est donnee aux developpements actuels de la recherche par rapport aux champs institutionnel et social dans lesquels ils ont evolue. Enfin, le stat…

Survey on the prevalence of leptospira infections in the Italian population.

1994

This investigation is the first nationwide survey on the circulation of leptospira infections in human beings in Italy. In nine out of twenty Italian regions, representative samples of the population were investigated for the presence of leptospira infections. Unexpectedly, leptospira infections were found to be widespread, the number of cases being much higher than the diagnosed clinical cases. There were found to be high, medium, and low risk areas. On the whole, the risk for the rural population was no higher than the risk for urban dwellers; leisure activities, contact with animals and residence on the plain versus residence in the hills were important risk factors. There was an unident…

Distribution of lymphocyte surface antigens in healthy neonates.

1994

Using flow cytometric analysis we investigated the distribution of major lymphocyte surface antigens in newborn infants. A total of 221 newborns entered the study, of whom 53 fullfilled our criteria of healthy mature neonates. Percentages of immunofluorescent-positive cells were as follows (median and range from 25th to 75th percentiles given): for CD1 3.8%; 2.3%–5.8%. CD2 60.9%; 52.4%–66.8%. CD3 57.5%; 50.5%–63.3%. TcRas 57.7%; 48.1%–60.0%. CD4 36.3%; 28.0%–42.6%. CD8 23.0%; 20.0%–27.4%. CD11a 56.3%; 46.3%–68.5%. CD19 12.1%; 8.6%–14.8%. CD20 10.9%; 8.4%–12.9%. CD25 2.6%; 2.1%–4.5%. CDw52 61.0%; 51.2%–76.1%. CD71 5.2%; 3.1%–9.3%. While the ranges for the percentage of immunofluorescent-posi…

A chematoxonomic review of the subtribe crepidinase based on its phenol constituents

1994

Abstract The chemotaxonomical significance of flavonoids, phenolic acids and coumarins from 20 species, belonging to eight genera of the subtribe Crepidinae (family Compositae), is discussed. The content in phenolic compounds of three species of Lactuca (L. tenerrima, L. virosa and L. muralis ) is reported for the first time.

Tumor-suppressor genes, hematopoietic malignancies and other hematopoietic disorders of Drosophila melanogaster.

1994

Stimulated Raman and Cars Spectroscopy of ν1 and 2ν2 (A1) Bands of 12CF4

1994

Two experimental coherent Raman techniques, stimulated Raman and coherent anti-Stokes Raman spectroscopy (CARS), were employed to study the Raman spectrum of CF 4 in the 900 cm −1 region. The stimulated Raman and CARS spectra of the ν 1 band of CF 4 were recorded at high resolution. The analysis of these spectra enabled some spectroscopic constants of this band to be refined and higher order constants to be determined for the first time. The first high-resolution CARS spectrum of the 2ν 2 (A 1 ) harmonic band is also presented. The rotational transitions of this band up to J = 40 were assigned and the first set of spectroscopic constants for this sub-level were determined. These results imp…

Vision evaluation in people with Down's syndrome.

1994

We tested the colour vision of 72 people with Down's syndrome using the Ishihara test and an anomaloscope. We found that 13 of the subjects, 6 males and 7 females, had defective colour vision according to Pickford's classification. In monocular vision 10 eyes were protan (five simple, three extreme and two deviant), one eye was simple deuteranomalous and the remaining eyes were normal: in binocular vision four of the subjects were protan (two simple and two deviant), two subjects were deutan (one simple and one deviant) and the rest were normal. Many of our subjects had lens opacities, strabismus, nystagmus, hypermetropia, high myopia and astigmatism, confirming literature reports. The cont…

INTERFACE TENSION AND CORRELATION LENGTH OF 2D POTTS MODELS: NUMERICAL VERSUS EXACT RESULTS

1994

I briefly review new analytical formulas for the correlation length and interface tension of two-dimensional q-state Potts models and compare them with numerical results from recent Monte Carlo simulation studies.

Stimulated Raman spectroscopy as the essential tool for studying collisional effects : application to combustion

1994

No abstract available

Transfer of Some Alkyl Substituted Ferrocenes from Water to Cationic Surfactant Micelles Studied by Kinetic Method

1994

Abstract Binding of ferrocene and its 1,1′-dimethyl and n -butyl derivatives to dodecyl and tetradecyltrimethylammonium nitrate micellar aggregates has been studied at 20.0°C and ionic strength 0.02 tool dm -3 by examining the micellar retarding effects on the rates of iron(III) oxidation of these substrates. Solubilization of the ferrocenes in the cationic micellar phase increases as the substrate hydrophobic character increases and, to a lesser extent, as the surfactant hydrocarbon chain length becomes longer. The critical micelle concentrations of the surfactants used and the incremental free energy of transfer of methylene groups of both the substrate and the surfactant from the aqueous…

TEMPERATURE DEPENDENT NOISY MODELS OF PSEUDOMORPHIC HEMTs

1994

From a complete characterization in terms of noise and scattering parameters carried out at room temperature in the 8–16 GHz frequency range, the noisy small‐signal model of a pseudomotphic HEMT series has been extracted. The transistor scattering parameters have been subsequently measured at lower temperatures (down to −50 °C) by placing the device text fixture in a thermo‐controlled chamber. The model effectiveness has then been tested by determining the circuit element values at the different temperatures and by observing the model noise performance.

PARLAMENTARISMO VS. PRESIDENCIALISMO: NUEVAS CONSTITUCIONES DE LA EUROPA ORIENTAL.

1994

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Anatomical correlates of visual and tactile extinction in humans: a clinical CT scan study.

1994

The anatomical correlates of tactile and visual extinction with double simultaneous stimulation were investigated in a series of 159 patients with right brain damage caused by stroke. Forty six patients showed extinction (22 tactile, 14 visual, 10 tactile and visual). Over 50% of the patients with extinction had deep lesions, which were found in about 25% of the patients with visuospatial neglect not associated with extinction. In the patients with extinction and cortico-subcortical damage the paraventricular occipital white matter and the dorsolateral frontal cortex were most often involved. By contrast, when neglect was also present, the lesions clustered in the inferior parietal lobule. …

Protein phosphorylation is induced in tobacco cells by the elicitor cryptogein

1994

Changes in plasmalemma ion fluxes were observed when tobacco (Nicotiana tabacum) cells were treated with cryptogein, a proteinaceous elicitor from Phytophthora cryptogea. A strong alkalization of the culture medium, accompanied by a leakage of potassium, was induced within a few minutes of treatment. These effects reached a maximum after 30 to 40 min and lasted for several hours. This treatment also resulted in a rapid, but transient, production of activated oxygen species. All these physiological responses were fully sensitive to staurosporine, a known protein kinase inhibitor. Furthermore, a study of protein phosphorylation showed that cryptogein induced a staurosporine-sensitive phosphor…

Molecular modifications—Mechanical behaviour relationships for gamma irradiated LLDPE/PA6 blends

1994

Abstract The molecular modifications, due to γ radiation under vacuum, of linear low density polyethylene/polyamide 6 blends are presented and related to their mechanical behaviour. Solubility and melt viscosity tests indicate that in blends the polyethylene component undergoes mainly crosslinking phenomena, whereas the main effect on polyamide is chain branching. According to these molecular modifications, the most relevant effect is the increase of the tensile modulus for the polyethylene rich blends and the increase of the impact strength for the polyamide rich blends.

The shared image guiding the treatment process. A precondition for integration of the treatment of schizophrenia.

1994

The aim of the study reported here was to develop psychotherapeutic in-patient treatment for acute schizophrenia, following the principles of a need-adapted approach. To improve the integration of experiences which hospital staff have with acutely psychotic patients and their families, systematic supervision sessions were organised. In these sessions, it was possible to achieve shared psychological images through which the whole staff could integrate patients' behaviour and symptoms, both symbolic and non-symbolic. Such an image was called ‘the shared image guiding the treatment process’ (SIGTP). The process of achieving the SIGTP was interpreted through Peircean semiotics, especially the c…

Über tetraaryl-methan-analoga in der gruppe 14

1994

Abstract The title compounds have been synthesized by Grignard reactions or pyrolysis of diplumbanes respectively. The crystal structures of m -Tol 4 Pb and Ph 4 Pb (redetermination) have been determined. All eight compounds (Ph/Tol) 4 (Sn/Pb) are S 4 symmetric and contracted along this unique axis. The 13 C-NMR chemical shifts and the couplings 1 J ( 119 Sn/ 207 Pb 13 C) as well depend additively upon the methyl substituents. The ratios 1 K ( 207 Pb 13 C): 1 K ( 119 Sn 13 C) of the reduced coupling constants are all near to 1.61; a comparison with values from the literature for alkyl, alkenyl and alkinyl substituents is given. The ratio δ( 207 Pb):δ( 119 Sn) results in 2.28. IR (700 dow…

A 60-night campaign on dwarf novae. - I. Photometric variability of SU UMa and YZ Cnc

1994

A 60-night campaign on SU UMa, YZ Cnc and some secondary targets was carried out during 1988 December and 1989 January at the Observatorio del Roque de Los Muchachos (the 1988 International Time Project). The aim was to study the behaviour of these dwarf novae through their outburst cycle. Here we present the overall light curves of the main targets, SU UMa and YZ Cnc, which show that the optical fluxes continue to decrease after the end of the outburst. For YZ Cnc we find that, during quiescence, orbital variability is present, which may be interpreted as modulation caused by the bright-spot region. Near the end of an outburst, a weak, sinusoidal variation is observed; we discuss the possi…

Low bioavailability of amoxicillin in rats as a consequence of presystemic degradation in the intestine.

1994

Several studies have been carried out to elucidate the causes of the low oral bioavailability of amoxicillin in rats. The hepatic first-pass effect of the antibiotic was estimated by comparing the area under the plasma drug concentration-versus-time curve from time zero to infinity (AUC0-infinity) obtained after injecting the drug into a mesenteric vein with the AUC0-infinity value obtained after injecting the drug into the jugular vein of conscious rats. No hepatic first-pass effect was detected. The bioavailability of amoxicillin after intraduodenal administration was only 51%, and the fraction of the dose remaining in the intestine at the end of the experiment was 4.5%. This was far less…

Simulation of13C NMR chemical shifts for polychlorinated and polybrominated oxybenzenes with two-particle increment scheme

1994

A two-particle system of OY-Cl and OY-Br mixed increments for predicting13C NMR chemical shifts of polyhalogenated polyoxybenzenes has been developed. It has been found that only theortho- and para-interactions of the OY and Hal substituents contribute significantly to the13C chemical shifts and that theortho-effects of the OY located between Ha1 and H and those of the OY located between two Ha1 atoms are different. Additional effects are due to solvating solvents. The increment scheme is predictive over the whole class of compounds under consideration and may be realized on personal computers.

Ileocecal valve reconstruction during continent urinary diversion.

1994

During construction of an ileocecal reservoir, such as the Mainz or Indiana pouch, the ileocecal valve is lost. Subsequently, the intestinal transit time is shortened and malabsorption as well as diarrhea may result. Patients having undergone previous bowel resection as well as children with myelomeningocele who often already have frequent defecations will be heavily affected by the loss of the ileocecal valve. We have functionally reconstructed the ileocecal valve by embedding ileum into the ascending colon via a submucosal tunnel in analogy to the technique used when creating the continence mechanism during the Mainz pouch procedure using the appendix. Experimental results in 15 dogs demo…

Nonlinear EEG dynamics during sleep in depression and schizophrenia.

1994

The article deals with the question, whether nonlinear analysis of the sleep EEG may give clues to understanding of disturbed information processing in psychiatric diseases. We point out how the nonlinear approach to EEG dynamics is motivated and review recent investigations concerning nonlinear dynamical properties of physiological systems. We present calculations of the correlation dimension D2 and the principal Lyapunov-exponent lambda 1 for sleep EEG data from 9 depressive and 11 schizophrenic inpatients compared to healthy controls. Combining the findings for D2 and lambda 1 our results point to altered nonlinear brain dynamics mainly during slow wave sleep in depression and during REM…

Multicanonical multigrid Monte Carlo method.

1994

To further improve the performance of Monte Carlo simulations of first-order phase transitions we propose to combine the multicanonical approach with multigrid techniques. We report tests of this proposition for the d-dimensional ${\mathrm{\ensuremath{\Phi}}}^{4}$ field theory in two different situations. First, we study quantum tunneling for d=1 in the continuum limit, and second, we investigate first-order phase transitions for d=2 in the infinite volume limit. Compared with standard multicanonical simulations we obtain improvement factors of several, and of about one order of magnitude, respectively.

Characteristic time scale of auroral electrojet data

1994

The structure function of the AE time series shows that the AE time series is self-affine such that the scaling exponent changes at the time scale of approximately 113 (±9) minutes. Autocorrelation function is shown to have scaling properties similar to those of the structure function. From this result it can be deduced that the time scale at which the scaling properties of the AE data change should equal the typical autocorrelation time of these data. We find the typical autocorrelation time of the AE data is 118 (±9) minutes. The characteristic time scale of the AE data appears as a spectral break in their power spectrum at a period of about twice the autocorrelation time.

Orthometalation reactions in trifluoroacetate dirhodium(II) compounds. Molecular structure of Rh2(O2CCF3)2[(C6H4)PPh2]2·(PPh3)2·2(C7H8)

1994

Abstract Rh 2 (O 2 CCF 3 ) 3 [(C 6 H 4 )PPh 2 ]·(HO 2 CCF 3 ) 2 reacts with PPh 3 yielding the doubly metalated compound Rh 2 (O 2 CCH 3 ) 2− [(C 6 H 4 )PPh 2 ] 2 ·(HO 2 CCF 3 ) 2 . The reaction proceeds via a reactive intermediate with an equatorial phosphine, Rh 2 (η 2 -O 2 CCF 3 )(μ-O 2 CCF 3 ) 2 [(C 6 H 4 )PPh 2 ](PPh 3 )·(HO 2 CCF 3 ), which can also be generated in moderate yield under photochemical conditions. The structure of the PPh 3 bis-adduct Rh 2 (O 2 CCF 3 ) 2 [(C 6 H 4 )PPh 2 ] 2 ·(PPh 3 ) 2 ·2(C 7 H 8 ) has been determined by X-ray diffraction. M r =1663.27, orthorhombic, space group Fdd 2, a =41.748(9), b =21.620(5), c =17.375(5) A, V =15683(6) A 3 , Z =8, D x =1.41 g cm −3…

Use of physicochemical processing in treating urban waste waters

1994

The principal objective of the present study was to compare two clearly defined purification processes in two stages: the periods 1985–1987 (conventional) and 1988–1990 (physico‐chemical). In general, the mean concentrations obtained were lower in the second period. A z‐test for comparing means was applied, but no significant correlation was observed (p ≤ 0.05). The mean concentrations obtained (with some exceptions) are lower in the second period. With the passing of time, the total volume of sewage flow has increased, and hence the load of contaminants has become diluted. The use of physico‐chemical treatment prior to biological processing may be the cause of the increase in cost.

Unicity of biproportion

1994

International audience; The biproportion of S on margins of M is called the intern composition law, K: (S,M) -> X = K(S,M) / X = A S B. A and B are diagonal matrices, algorithmically computed, providing the respect of margins of M. Biproportion is an empirical concept. In this paper, the author shows that any algorithm used to compute a biproportion leads to the me result. Then the concept is unique and no longer empirical. Some special properties are also indicated.

Single-cluster Monte Carlo study of the Ising model on two-dimensional random lattices.

1994

We use the single-cluster Monte Carlo update algorithm to simulate the Ising model on two-dimensional Poissonian random lattices with up to 80,000 sites which are linked together according to the Voronoi/Delaunay prescription. In one set of simulations we use reweighting techniques and finite-size scaling analysis to investigate the critical properties of the model in the very vicinity of the phase transition. In the other set of simulations we study the approach to criticality in the disordered phase, making use of improved estimators for measurements. From both sets of simulations we obtain clear evidence that the critical exponents agree with the exactly known exponents for regular latti…

Induction of hapten-specific tolerance by interleukin 10 in vivo.

1994

Interleukin 10 (IL-10) is released during the induction phase of contact sensitivity and was shown in prior functional studies to convert epidermal Langerhans cells (LC) from potent inducers of primary immune responses to specifically tolerizing cells in vitro. To investigate whether IL-10 also subserves the function of a tolerizing agent in vivo ears of BALB/c or C3H mice were injected intradermally with 1-2 micrograms of recombinant mouse (rm)IL-10 8 h before epicutaneous application of 3% trinitrochlorobenzene (TNCB; a contact allergen). As a control, mice were injected with phosphate-buffered saline or IL-10 plus neutralizing amounts of anti-IL-10 mAb. 5 d later, mice were challenged wi…

A fast kinetic method for assessing mitochondrial membrane potential in isolated hepatocytes with rhodamine 123 and flow cytometry

1994

Rhodamine 123 (Rh123) is widely used as a flow cytometric probe for mitochondrial membrane potential (MMP) in metabolic, pharmacologic, and toxicological studies. However, the use of relatively high concentrations of Rh123 (up to 10 micrograms/ml) and prolonged incubation times (up to 1 h), including washing steps, may be inconvenient for certain applications in which labile cells are used or which demand rapid or repeated analysis. In this paper we describe a rapid kinetic assay of MMP in isolated rat hepatocytes, based upon the quantitation of the initial rate of Rh123 uptake by living cells, selected by their scattering properties. The results indicate that at an appropriate dye-to-cell …

El feminismo como crítica filosófica

1994

Voy a centrarme en el concepto de «critica» como nocion clave, tanto en una teoria de la modernidad como de la racionalidad, y calibrar la importancia que tiene para el feminismo. Mi punto de partida es que el feminismo es, fundamentalmente, «critica filosofica». y lo es, aparte de ser otras muchas cosas: una teoria politica, una propuesta para la emancipacion de las mujeres. un movimiento reivindicativo, una revalorizacion de las mujeres como genero, una afirmacion del sujeto femenino, de las mujeres como sujetos, etc. Sin embargo, 10 que le confiere un lugar teorico relevante, a tener en cuenta necesariamente en filosofia, es su caracter de critica. En Hacia una critica de la razon patria…

Lung-worms (Nematoda: Pseudaliidae) of harbour porpoises (Phocoena phocoena) in Norwegian waters: patterns of colonization

1994

SUMMARYWe studied the component community of lung-worms of the harbour porpoise, attempting to establish the relative importance of ecological and evolutionary factors on its development. The lungs of 64 porpoises by-caught in Norwegian waters were examined for helminths. Three pseudaliid species were detected. The porpoises appear to be readily colonized by lung-worms, the structure of the component community of calves being fairly similar to that of the remainder. Prenatal and/or transmammary infections might partly account for these early infections. However, host age was correlated with the number of lung-worm species, suggesting that the lung-worms may have heteroxenous cycles similar …

Duodenal ulcer healing drugs

1994

MEETING REPORT

1994

QED one-loop corrections to radiative muon decay

1994

Based upon the Fermi interaction, the differential decay rate of the radiative muon decay including one-loop radiative corrections is determined to the order ${G}_{F}^{2}{\ensuremath{\alpha}}^{2}$. Essential aspects of the calculation are exhibited. After cancellation of IR divergences, the double radiative muon decay is included. Some initial applications are considered.