showing 36 of ~574560 from 574555 documents
The extended late career phase – examining senior nursing professionals
2021
PurposeBy relying on a sustainable career perspective and recent studies on senior employees’ late career phase, this study aims to examine senior (50+) nurses’ late career narratives in the context of extending retirement age. Given the current global nursing shortage, there is a pressing need to find ways on how to promote longer and sustainable careers in the health-care field. Yet, there is limited knowledge about the extended late career phase of senior nurses.Design/methodology/approachEmpirical data were derived from 22 interviews collected among senior (50+) nursing professionals working in a Finnish university hospital. The qualitative interview data were analysed using a narrative…
Teaching and Learning of Geometry as a process of Objectification: conditions and obstacles to argumentation and proof. The role of natural language,…
2021
This paper examines some examples (taken from research conducted over the years) that show students’ linguistic attitudes in geometry tasks. The examples are framed within the Theory of Objectification with reference to the notion of sensuous cognition, semiotic means of objectification and levels of generality. We show the struggle students live, at higher levels of generality, in intertwining natural language, specific language and the spontaneous use of geometrical figures, bound to perception and kinaesthetic activity. Within the networking paradigm, we coordinate the Theory of Objectification and Duval’s semio-cognitive approach to frame the interplay between the ideal and the material…
Usage du numérique et médiation muséale
2021
International audience; 4 communications qui font voyager. On y parlera immersion muséale, jeunes publics, critiques amateurs, et…contexte pandémique. Autant de pratiques et de publics en contexte numérique. D’un cadre à l’autre, se joue toujours l’articulation entre dispositif, disposition et disponibilité. - Dispositif à la fois matériel et immatériel, physique et sensible, pratique et symbolique- Disposition des publics c’est-à-dire entrée dans le dispositif, l’envie d’agir, se mouvoir et s’émouvoir. S’immerger et faire au besoin le pas de côté par rapport aux itinéraires ouparcours balisés, préfigurés. Le fameux chiasme entre ce que le dispositif me fait et ce que je fais au dispositif-…
Les appropriations de l’antibiorésistance en France : la carrière d’un problème public au sein de la presse vétérinaire (2006 – 2014). in « Croisades…
2021
International audience
The GRP94 Inhibitor PU-WS13 Decreases M2-like Macrophages in Murine TNBC Tumors: A Pharmaco-Imaging Study with 99mTc-Tilmanocept SPECT
2021
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancers and is not eligible for hormone and anti-HER2 therapies. Identifying therapeutic targets and associated biomarkers in TNBC is a clinical challenge to improve patients’ outcome and management. High infiltration of CD206+ M2-like macrophages in the tumor microenvironment (TME) indicates poor prognosis and survival in TNBC patients. As we previously showed that membrane expression of GRP94, an endoplasmic reticulum chaperone, was associated with the anti-inflammatory profile of human PBMC-derived M2 macrophages, we hypothesized that intra-tumoral CD206+ M2 macrophages expressing GRP94 may represent innovative…
SINTESI STEREOSELETTIVA IN IONO-EUTECTOGEL SUPRAMOLECOLARI
2021
Soluble Complexes of Cobalt Oxide Fragments Bring the Unique CO2 Photoreduction Activity of a Bulk Material into the Flexible Domain of Molecular Sci…
2021
The deposition of metal oxides is essential to the fabrication of numerous multicomponent solid-state devices and catalysts. However, the reproducible formation of homogeneous metal oxide films or of nanoparticle dispersions at solid interfaces remains an ongoing challenge. Here we report that molecular hexaniobate cluster anion complexes of structurally and electronically distinct fragments of cubic-spinel and monoclinic Co3O4 can serve as tractable yet well-defined functional analogues of bulk cobalt oxide. Notably, the energies of the highest-occupied and lowest-unoccupied molecular orbitals (HOMO and LUMO) of the molecular complexes, 1, closely match the valence- and conduction-band (VB…
Introduction: Epistemologies of the match
2021
Algorithmically driven online dating platforms today promise the ability to sort through relevant data and identify one's ideal amorous matches effectively. Yet the appeal of technological and scientific solutions to the messy problem of finding partners is hardly new. This introduction to the Focus section 'It's a Match!' argues that the history of amorous matching has long been part and parcel of the history of science, in particular the social sciences. Taking matching as an 'applied science of social harmony,' the authors argue that concern over more reliable techniques for determining the suitability of partners has formed an essential part of both the maintenance of social order and t…
Systematic investigation of the adsorption and inhibition properties of a new clickable 1,2,3‐triazole compound for mild steel in 1 M HCl medium
2021
Is Finnish Corporatism Reconfiguring, and Is It Good for Gender Equality?
2021
The Nordic model of employment relations, characterised by centralised collective bargaining and strong collaboration between social partners and the state, has often been linked to positive gender equality outcomes. Although the Nordic model has maintained stability even in the economic crisis of 2008, the Finnish labour market was faced with neoliberal pressures for change, liberalisation and decentralisation and a belief in the necessity of internal devaluation to restore national competitiveness. This chapter focuses on recent developments within the Finnish corporatist system and whether these changes have implications for gender equality. We argue that Finnish corporatism has not alwa…
Guanidinoacetic Acid Consumption via Regular Diet in Adults
2021
La contribución de las cooperativas de crédito para aliviar la exclusión financiera geográfica en los espacios menos poblados. El caso de España
2021
La crisis asociada a la Covid ha puesto de manifiesto nuevamente la relevancia del sistema financiero. La pasada crisis, de carácter financiero había impactado intensamente en el sistema bancario, provocando un fuerte retroceso en la actividad crediticia, lo que, en muchos casos se ha traducido en riesgo creciente de exclusión financiera, sobre todo en aquellos territorios en retroceso demográfico. En este contexto, las cooperativas de crédito, caracterizadas por su reducido tamaño, localismo y vocación de banca de proximidad, han sufrido un deterioro patrimonial menos acusado que el resto de las entidades del sistema bancario. Además, actúan en las áreas donde la densidad de población es m…
Cloud droplet formation at the base of tropical convective clouds: closure between modeling and measurement results of ACRIDICON–CHUVA
2021
Aerosol–cloud interactions contribute to the large uncertainties in current estimates of climate forcing. We investigated the effect of aerosol particles on cloud droplet formation by model calculations and aircraft measurements over the Amazon and over the western tropical Atlantic during the ACRIDICON–CHUVA campaign in September 2014. On the HALO (High Altitude Long Range Research) research aircraft, cloud droplet number concentrations (Nd) were measured near the base of clean and polluted growing convective cumuli using a cloud combination probe (CCP) and a cloud and aerosol spectrometer (CAS-DPOL). An adiabatic parcel model was used to perform cloud droplet number closure studies for fl…
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
2021
Abstract SARS-CoV-2 vaccine ChAdOx1 nCoV-19 (AstraZeneca) causes a thromboembolic complication termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Using biophysical techniques, mouse models, and analysis of VITT patient samples, we identified determinants of this vaccine-induced adverse reaction. Super-resolution microscopy visualized vaccine components forming antigenic complexes with platelet factor 4 (PF4) on platelet surfaces to which anti-PF4 antibodies obtained from VITT patients bound. PF4/vaccine complex formation was charge-driven and increased by addition of DNA. Proteomics identified substantial amounts of virus production-derived T-REx HEK293 proteins in the ethyle…
Lightning-ignited wildfires and long continuing current lightning in the Mediterranean Basin: Preferential meteorological conditions
2021
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Impact of Perceived Stress and Immune Status on Decision-Making Abilities during COVID-19 Pandemic Lockdown.
2021
The ability to make risky decisions in stressful contexts has been largely investigated in experimental settings. We examined this ability during the first months of COVID-19 pandemic, when in Italy people were exposed to a prolonged stress condition, mainly caused by a rigid lockdown. Participants among the general population completed two cognitive tasks, an Iowa Gambling Task (IGT), which measures individual risk/reward decision-making tendencies, and a Go/No-Go task (GNG), to test impulsivity, together with two questionnaires, the Perceived Stress Scale and the Depression, Anxiety and Stress Scales. The Immune Status Questionnaire was additionally administered to explore the impact of t…
Rotavirus and the web: analysis of online conversations in Italy during 2020
2021
Rotavirus is the most common cause of severe diarrhea among children worldwide. In 2017, Italy included rotavirus vaccination in its National Immunization Program. The use of social media monitoring, an efficient tool to understand vaccine hesitancy, has increased in recent years; however, only a few examples of such monitoring are available for Italy. Present study analyzed content on online sources, including social media, to identify factors contributing to Italian parents' decisions to vaccinate or not their children against rotavirus. Blogmeter Suite was used to search and analyze conversations related to rotavirus in Italian on online sources during 2020. These data were compared with…
Regorafenib Efficacy After Sorafenib in Patients With Recurrent Hepatocellular Carcinoma After Liver Transplantation:A Retrospective Study
2021
Background and aim Safety of regorafenib in hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) has been recently demonstrated. We aimed to assess the survival benefit of regorafenib compared to best supportive care (BSC) in LT-patients after sorafenib discontinuation. Methods This observational multicenter retrospective study included LT-patients with HCC-recurrence who discontinued first-line sorafenib. Group-1 was constituted by regorafenib-treated patients, while control group was selected among patients treated with best supportive care (BSC) due to unavailability of second-line options at the time of sorafenib discontinuation and who were sorafenib-tolerant prog…
Identification of biomarkers in wastewater-based epidemiology: Main approaches and analytical methods
2021
Wastewater-based epidemiology (WBE) has become popular to estimate the use of drugs of abuse and recently to establish the incidence of CoVID 19 in large cities. However, its possibilities have been expanded recently as a technique that allows to establish a fingerprint of the characteristics of a city, such as state of health/disease, healthy/unhealthy living habits, exposure to different types of contaminants, etc. with respect to other cities. This has been thanks to the identification of human biomarkers as well as to the fingerprinting and profiling of the characteristics of the wastewater catchment that determine these circumstances. The purpose of this review is to analyze the differ…
Menetelmällistä rajankäyntiä ja tieteiden välisyyttä
2021
Marianne Silén: Sosiologian ja tilastotieteen rajoilla – faktorianalyysi rajakohteena. Acta electronica Universitatis Lapponiensis 301. Rovaniemi: Lapin yliopisto, 2021, 175 s. I S B N 978-952-337-248-1
The Aged Lower Urinary Tract: Deficits in Neural Control Mechanisms.
2021
Bothersome urinary symptoms plague many older adults and disproportionally affect women. Underreporting of symptoms and general stigma/embarrassment associated with incontinence has negatively impacted the availability of treatments, as research cannot be championed if the severity of the problem is not apparent. Available therapeutics have limited efficacy and are often not recommended in aged patients. Lower urinary tract function has a long and rich history in animal studies; while much of the underlying anatomy has been described, including neural control mechanisms, the impact of aging has only just begun to be addressed. Recent work has provided strong evidence that neural control ove…
Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus.
2021
Soya consumption can decrease oxidative stress in animal models. Moreover, phytoestrogens such as genistein, present in soya, can mimic some of the beneficial effects of estrogens and are devoid of significant side effects, such as cancer. In this study, we have performed a controlled lifelong study with male OF1 mice that consumed either a soya-free diet or a soya-rich diet. We show that, although we found an increase in the expression and activity of antioxidant enzymes in soya-consuming mice, it did not increase lifespan. We reasoned that the soya diet could not increase lifespan in a very healthy population, but perhaps it could extend health span in stressed animals such as type 2 diab…
Workload, job satisfaction and occupational stress in Polish midwives before and during the COVID-19 pandemic
2021
Background The aim of this study was to describe, explain, and compare the correlations between workload, job satisfaction, and occupational stress levels in Polish midwives working before and during the COVID-19 pandemic. Material and Methods This study was cross-lagged in nature and conducted in 2 phases at public health facilities. The first phase took place between March and August 2018 before the current pandemic, and the second in February 2021. In total, 133 midwives working before the COVID-19 pandemic and 92 midwives working during the pandemic were surveyed. Results Analysis revealed that working during the pandemic, personal SARS-CoV-2 infection and workload were positive predict…
Reflections on dialogicity: Challenges and suggestions by mathematics student teachers
2021
Abstract Research related to dialogic teaching has been gaining ground in recent decades. On a theoretical level, researchers have described how sociocultural approaches are linked to dialogic teaching. In addition, empirical studies have explained how dialogic teaching manifests itself in educational dialogue and classroom interactions. However, studies addressing how the dialogic theory and practice could be linked meaningfully in teacher education and professional development programs in subject teacher education and related praxis are still limited. Especially in the case of math teacher education, the reported professional development programs are limited in number. Whereas the tendenc…
On Defining the Participatory Museum: The Case of the Museum of the Second World War in Gdansk
2021
This article seeks to contribute to the current debate on the new definition of the “museum” – a debate which led to turmoil at the 2019 ICOM General Assembly in Kyoto. With reference to the case study of the Museum of the Second World War in Gdansk (MSWW), it analyses the new and very successful genre of the narrative museum, a genre which arguably fulfils the core elements of the definition currently being discussed by ICOM. In this regard, it brings into focus the paramount importance of community involvement in creating and managing narrative museums – an aspect that has been virtually absent in the academic and media debates over the nature of the MSWW and its programme. By pointing ou…
The impact of institutional and macroeconomic conditions on aggregate business bankruptcy
2021
Abstract This paper investigates the aggregate business bankruptcy in relation to three macro-level factors: the government effectiveness, entrepreneurship activity and control of corruption for six European countries during the period from 2004 to 2017. We employ fuzzy-set qualitative comparative analysis (fsQCA) and partial least squares regression (PLS). Our findings show that countries with a high level of new firm creation and entrepreneurial activity can lead to a rise in the number of company failures. Furthermore, countries with a low corruption index and high levels of government effectiveness can mitigate insolvency. Our results have several policy implications for the evaluation …
Effects of low laser level therapy in rehabilitation of patients with COVID19 pneumonia
2021
Introduction. An unprecedented public health crisis has been triggered worldwide by SARS-CoV-2’s high contagiosity and it’s mortality rates of 1-5%. Although the majority of COVID-19 cases have a good outcome, there is a small percentage that develop severe pneumonia and citokine storm and may be in the need of mechanical ventilation. Methods. Identifying the exact drivers of the excessive inflammation and the biomarkers that can predict a hyperinflammatory response to SARS-CoV-2 would be extremly helpful in finding efficient anti-inflammatory interventions that may stop the progression to acute respiratory distress syndrome (ARDS). Results. In the search for such interventions we have iden…
High-Resolution 3-D CZT Drift Strip Detectors for Prompt Gamma Ray and Neutron Detection in BNCT
2021
Spectroscopic imagers based on high-Z and wide-bandgap compound semiconductor detectors are widely proposed for the detection of prompt gamma rays in boron neutron capture therapy (BNCT). BNCT is a therapy based on the neutron capture reaction 10B (n,α)7Li. To perform a real-time monitoring of the spatial distribution of 10B during the treatments, the detection of the prompt gamma rays (478 keV), produced by the 7Li recoil nuclei, can be helpful. In this work, we presented the potentialities of new high-resolution CZT drift strip detectors, recently developed by our group, for BNCT measurements. The detectors, exploiting the analysis of the collected-induced charge pulses from anodes, catho…
Design of a Low Cost 3D Printable Single-Component Compliant Mechanism for FWMAV’s Wing Actuation
2021
Considering a modern approach to design, one of the viable options for developing innovative projects is the possibility of integrating the effectiveness of the solutions offered by nature and living beings with the latest design methods. With this in mind, the following research exploits the idea of reproducing the natural flexibility inherent in biological structures by combining the advantages of compliant mechanisms with the adaptability of additive manufacturing processes. In the specific, the authors intend to highlight the potential and critical aspects of a possible approach for the application of compliant mechanisms in the development of single-component structures suitable for th…
The acute effects of different high-intensity conditioning activities on sprint performance differ between sprinters of different strength and power …
2021
The purpose of the present study was to examine the effect of different conditioning activities (CAs) on short-term increase in sprint performance. In twelve male sprinters (21.1+2.6 years, 100 m performance: 11.5+0.6 s) their body composition, half squat maximum strength, 100 m sprinting and countermovement jump performances were evaluated. The performance of a 50 m sprint (splits at 10 m, 30 m and 50 m) was evaluated before and 5, 10 and 15 min after four postactivation performance enhancement CAs on different occasions: [1] 3 sets x 4 s maximum isometric half squat (IHF), [2] 3 sets x 3 consecutive countermovement jumps (cCMJs), [3] 3 repetitions x 30 m overspeed sprinting (OVSP) and [4]…
Conceptions of Assessment as an Integral Part of Language Learning: A Case Study of Finnish and Chinese University Students
2021
Assessment is viewed as an internal and pivotal part of learning, where cultural factors, previous experiences, and future aspirations affect learners’ perceptions. In recent years, an increasing number of western universities have established their campuses or “dual” programmes in China. In the first Sino–Finnish programme, 293 Finnish and Chinese students participated in the same English for Specific Purposes (ESP) course. This study investigated students’ perceptions of assessment through an adapted version of the “Students’ Conceptions of Assessment” inventory, and it explored if the responses on each conception differ between the groups. …
RETROFITTING DETENTION BUILDINGS OF HISTORICAL-CULTURAL INTEREST. A CASE STUDY IN ITALY
2021
Penitentiary buildings in Italy include many buildings of undoubted historical and architectural importance. These have been, or will soon be, subject to structural changes necessary to adapt their spaces to the current regulations of prisons. The idea of punishment itself has changed over the centuries, so it is a physiological necessity to adapt existing buildings accordingly. When, however, such buildings date back centuries, they should not be considered a mere container but a historical testimony rich in meaning for the entire nation. The characteristics of the materials, distribution, and what these buildings have represented for the city should be the object of study and protection, …
Significance of the pulsed dye laser in treatment of acral infantile hemangioma
2021
Trophic ecology of a Late Pleistocene early modern human from tropical Southeast Asia inferred from zinc isotopes
2021
Tam Pà Ling, a cave site in northeastern Laos, has yielded the earliest skeletal evidence of Homo sapiens in mainland Southeast Asia. The reliance of Pleistocene humans in rainforest settings on plant or animal resources is still largely unstudied, mainly due to poor collagen preservation in fossils from tropical environments precluding stable nitrogen isotope analysis, the classical trophic level proxy. However, isotopic ratios of zinc (Zn) in bioapatite constitute a promising proxy to infer trophic and dietary information from fossil vertebrates, even under adverse tropical taphonomic conditions. Here, we analyzed the zinc isotope composition (66Zn/64Zn expressed as δ66Zn value) in the en…
Ácido tranexámico en cirugía cardíaca: ¿las dosis bajas son suficientes?
2021
Resumen Objetivos El acido tranexamico se utiliza para prevenir la hiperfibrinolisis y disminuir el sangrado postoperatorio y el empleo de hemoderivados en cirugia cardiaca con circulacion extracorporea. Este trabajo evalua la eficacia de dosis bajas o altas de acido tranexamico mediante un estudio de cohortes, prospectivo, realizado en 2 hospitales de Valencia. Material y metodos Se seleccionaron 427 pacientes, 207 en el Hospital General Universitario (dosis bajas [DB]) y 220 en el Hospital Universitario y Politecnico La Fe (dosis intermedias [DI] y dosis altas [DA]), entre enero de 2019 y enero de 2020. Se estudio la presencia de hiperfibrinolisis por tromboelastometria rotacional, la adm…
Fear of Coronavirus, Stress and Fear of Childbirth in Polish Pregnant Women during the COVID-19 Pandemic
2021
The COVID-19 pandemic is the largest pandemic of an aggressive coronavirus in the human population in the 21st century. The pandemic may have a negative emotional impact on pregnant women, causing fear and stress. Negative feelings during pregnancy later affect fear of childbirth. Our study aimed to determine the relationship between fear of COVID-19, stress and fear of childbirth. We assume that fear of COVID-19 will be a mediator of the relationship between perceived stress and fear of childbirth. A total of 262 Polish pregnant women participated in this study. Perceived Stress Scale (PSS-10), Fear of COVID-19 Scale (FOC-6) and Labour Anxiety Questionnaire (KLP II) were used in the study.…