showing 36 of ~574560 from 574555 documents
Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review
2021
Curcuma longa L. rhizome essential oil is a valuable product in pharmaceutical industry due to its wide beneficial health effects. Novel applications in the agri-food industry where more sustainable extraction processes are required currently and safer substances are claimed for the consumer are being investigated. This review provides information regarding the conventional and recent extraction methods of C. longa rhizome oil, their characteristics and suitability to be applied at the industrial scale. In addition, variations in the chemical composition of C. longa rhizome and leaf essential oils regarding intrinsic and extrinsic factors and extraction methods are also analysed in order to…
Recensione di MAURIZIO CARTA: CITTÀ AUMENTATE. DIECI GESTI-BARRIERA PER IL FUTURO - IL MARGINE. TRENTO 2021
2021
Il testo è la recensione del volume di cui al titolo a partire da una riflessione sulle relazioni tra Uomo e Pianeta The text is the review of the volume referred to in the title starting from a reflection on the relations between Man and Planet
"E' la stampa bellezza!": la corte costituzionale alle prese con la risposta carceraria alle lesioni mediatiche della reputazione
2021
L'articolo analizza in chiave critica la posizione assunta dalla Corte costituzionale italiana in ordine ai criteri che il giudice penale è tenuto ad osservare nella scelta tra sanzione detentiva o pecuniaria in materia di diffamazioni commesse col mezzo della stampa o con altro mezzo di diffusione. .
In favour of layered feet: A response to Golston
2021
In this response we argue that the factorial typology predicted in Martínez-Paricio & Kager (2015), which representationally relies on the existence of internally layered ternary feet, is complete and accurate. We demonstrate it does not suffer from the problematic cases of overgeneration pointed out by Golston (this issue). Additionally, we corroborate the idea that the internally layered ternary foot is a metrical representation that is typologically warranted for stress phenomena as well as for segmental and tonal metrically conditioned distributions. We suggest that Golston's claim that "no stress system requires internally layered ternary feet" appears to be too strong and is not empir…
Predictors of nurses' attitudes and knowledge towards pain management in Italy. A cross-sectional study in the hospital settings.
2021
Abstract Introduction Pain is multidimensional, and as such it is the chief reason patients require urgent health care services. If inadequately assessed and untreated, pain may negatively impact on the quality of life of the patient. Pain management is an essential part of Nursing. The aim to this study is to examine the level of knowledge and attitudes with regard to pain among Italian nurses who work in clinical settings. Methods The Ferrell and McCaffery's Knowledge and Attitudes Survey Regarding Pain was distributed to 266 nurses employed in one specialized hospital in Rome, Italy. The staff in the survey work in three different settings: the intensive care unit, the sub-intensive care…
El impacto social de un evento deportivo mediano recurrente: El caso del Maratón de Valencia
2021
El objetivo de este estudio es analizar la percepcion de los residentes de la ciudad de Valencia sobre el impacto social de la Maraton de Valencia Trinidad Alfonso e identificar los factores en los que se agrupan los indicadores de impactos percibidos. Se recogio una muestra de 391 residentes en la ciudad, mediante un muestreo de conveniencia, con una edad media de 34.26 (DT=11.78) y una distribucion de 56.5% eran hombres y un 43.5% eran mujeres. Se utilizaron 32 items, evaluados en una escala Likert de cinco puntos, sobre posibles beneficios y costes asociados a la celebracion del evento en la ciudad. Se realizo un analisis factorial exploratorio que permitio identificar cinco factores: be…
Role of prenatal magnetic resonance imaging in fetuses with isolated severe ventriculomegaly at neurosonography: A multicenter study.
2021
Objective: The aim of this study was to report the rate of additional anomalies detected exclusively at prenatal magnetic resonance imaging (MRI) in fetuses with isolated severe ventriculomegaly undergoing neurosonography. Method: Multicenter, retrospective, cohort study involving 20 referral fetal medicine centers in Italy, United Kingdom, Spain and Denmark. Inclusion criteria were fetuses affected by isolated severe ventriculomegaly (≥15 mm), defined as ventriculomegaly with normal karyotype and no other additional central nervous system (CNS) and extra-CNS anomalies on ultrasound. In all cases, a multiplanar assessment of fetal brain as suggested by ISUOG guidelines on fetal neurosonogra…
Digital Pathology Enables Automated and Quantitative Assessment of Inflammatory Activity in Patients with Chronic Liver Disease
2021
Traditional histological evaluation for grading liver disease severity is based on subjective and semi-quantitative scores. We examined the relationship between digital pathology analysis and corresponding scoring systems for the assessment of hepatic necroinflammatory activity. A prospective, multicenter study including 156 patients with chronic liver disease (74% nonalcoholic fatty liver disease-NAFLD, 26% chronic hepatitis-CH etiologies) was performed. Inflammation was graded according to the Nonalcoholic Steatohepatitis (NASH) Clinical Research Network system and METAVIR score. Whole-slide digital image analysis based on quantitative (I-score: inflammation ratio) and morphometric (C-sco…
Liposomes as nonspecific nanocarriers for 5-Fluorouracil in the presence of cyclodextrins
2021
Abstract 5-Fluorouracil (5-FU) is one of anticancer drugs with broad activity. Due to its severe side effects, recent studies concentrate on new ways of directed 5-FU delivery and its release in ill tissue. One of selective carriers could be cyclodextrins and liposomes. The combination of novel methods, leading to formation of inclusion complexes (IC) between host molecule of β-cyclodextrin (β-CD) or 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) and 5-FU guest and its subsequent encapsulation in dipalmitoylphosphatidylcholine (DPPC) liposomes is studied experimentally in the present work. Several methods are applied to proof the encapsulation of the analysed drug and its release over time at 37 …
Long-Term Exposure to Transportation Noise and Risk for Type 2 Diabetes in a Nationwide Cohort Study from Denmark
2021
Background: Epidemiologic studies have linked transportation noise to increased morbidity and mortality, particularly for cardiovascular outcomes. However, studies investigating metabolic outcomes such as diabetes are limited and have focused only on noise exposures estimated for the loudest residential façade. Objectives: We aimed to examine the influence of long-term residential exposure to transportation noise at the loudest and quietest residential façades and the risk for type 2 diabetes. Methods: Road traffic and railway noise exposures (Lden) at the most and least exposed façades were estimated for all dwellings in Denmark during 1990–2017. Aircraft noise was estimated in 5-dB catego…
The degradation of intracrystalline mollusc shell proteins: a proteomics study of Spondylus gaederopus.
2021
Mollusc shells represent excellent systems for the preservation and retrieval of genuine biomolecules from archaeological or palaeontological samples. As a consequence, the post-mortem breakdown of intracrystalline mollusc shell proteins has been extensively investigated, particularly with regard to its potential use as a "molecular clock" for geochronological applications. But despite seventy years of ancient protein research, the fundamental aspects of diagenesis-induced changes to protein structures and sequences remain elusive. In this study we investigate the degradation of intracrystalline proteins by performing artificial degradation experiments on the shell of the thorny oyster, Spo…
Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care expert consensus statement on the use of lung ultrasound in critically il…
2021
Abstract Background To produce statements based on the available evidence and an expert consensus (as members of the Lung Ultrasound Working Group of the Italian Society of Analgesia, Anesthesia, Resuscitation, and Intensive Care, SIAARTI) on the use of lung ultrasound for the management of patients with COVID-19 admitted to the intensive care unit. Methods A modified Delphi method was applied by a panel of anesthesiologists and intensive care physicians expert in the use of lung ultrasound in COVID-19 intensive critically ill patients to reach a consensus on ten clinical questions concerning the role of lung ultrasound in the following: COVID-19 diagnosis and monitoring (with and without i…
A pilot-plant for the selective recovery of magnesium and calcium from waste brines
2021
Abstract The problem of brines disposal has raised great interest towards new strategies for their valorisation through the recovery of minerals or energy. As an example, the spent brine from ion exchange resins regeneration is often discharged into rivers or lakes, thus impacting on the process sustainability. However, such brines can be effectively reconcentrated, after removal of bivalent cations, and reused for the resins regeneration. This work focuses on developing and testing a pilot plant for selective recovery of magnesium and calcium from spent brines exploiting a novel proprietary crystallization unit. This is part of a larger treatment chain for the complete regeneration of the …
Marqueurs inflammatoires pour le diagnostic précoce d’infection postopératoire : le même seuil pour la chirurgie rectale et colique ?
2021
Resume Introduction La fistule anastomotique est la complication redoutee apres chirurgie colorectale. De nombreux travaux ont montre l’interet du dosage de la CRP en postoperatoire comme marqueur diagnostic precoce. Le seuil critique des marqueurs biologiques de l’inflammation doit-il rester le meme que la resection soit colique ou rectale ? Patients et methode Il s’agit d’une etude basee sur une cohorte constituee entre 2011 et 2014, incluant 497 patients avec une resection colorectale programmee. La proteine C-reactive et la pro-calcitonine ont ete mesurees tous les jours entre la veille et le 4e jour. Toutes les complications postoperatoires intra-abdominales ont ete considerees comme u…
Modelling of asymmetric nanojets in coronal loops
2021
Context. Observations of reconnection jets in the solar corona are emerging as a possible diagnostic for studying highly elusive coronal heating. Such jets, and in particular those termed nanojets, can be observed in coronal loops and have been linked to nanoflares. However, while models successfully describe the bilateral post-reconnection magnetic slingshot effect that leads to the jets, observations reveal that nanojets are unidirectional or highly asymmetric, with only the jet travelling inward with respect to the coronal loop’s curvature being clearly observed. Aims. The aim of this work is to address the role of the curvature of the coronal loop in the generation and evolution of asym…
Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study
2021
Background The prevalences of obstructive and restrictive spirometric phenotypes, and their relation to early-life risk factors from childhood to young adulthood remain poorly understood. The aim was to explore these phenotypes and associations with well-known respiratory risk factors across ages and populations in European cohorts. Methods We studied 49 334 participants from 14 population-based cohorts in different age groups (≤10, >10–15, >15–20, >20–25 years, and overall, 5–25 years). The obstructive phenotype was defined as forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) z-score less than the lower limit of normal (LLN), whereas the restrictive phenotype was defined a…
Finnish education system as seen from an Indonesian perspective
2021
The aim of this paper is to discuss the Finnish education system from an Indonesian perspective, and consider what citizens, notably from middle-income countries, may learn from the Finnish system. The source material is the author’s book, which provides an Indonesian perspective on the Finnish education system, supplemented by discussions from webinars and weekly Instagram Live discussions on the topic. It is known that education is part of a country’s culture, thus the Finnish education system cannot simply be implemented as such in another place. Yet there certainly are elements that can be adopted to the local culture, in this case, in Indonesia. The different models of education in Fi…
La polarità destra-sinistra e le direzioni cardinali: lingua, corpo e cultura
2021
Questo lavoro indaga un’antica questione relativa all’origine e all’uso dei termini ‘destra’ e ‘sinistra’ nelle lingue indoeuropee. Se sul piano fonetico e morfologico si ricostruiscono con facilità le radici comuni da cui derivano entrambi i termini nelle diverse lingue della stessa famiglia, sul piano della ricostruzione semantica e culturale emergono contraddizioni a tutt’oggi non spiegate. Qui si cerca di interpretare i dati sulla base non solo degli esiti morfologici della comparazione lessicale, ma anche del contesto storico e culturale ricostruito alla luce delle nuove prospettive offerte sia dalla linguistica tipologica sia dalla linguistica cognitiva. L’indagine si concentra in par…
Effectiveness of Pre-Hospital Tourniquet in Emergency Patients with Major Trauma and Uncontrolled Haemorrhage: A Systematic Review and Meta-Analysis
2021
Trauma is one of the leading causes of uncontrolled haemorrhage, death, and disability. Use of a tourniquet can be considered an optimal anti-haemorrhagic resource, in pre-hospital and emergency settings, and its lifesaving effect is clinically contradictory. This review aims to assess the clinical efficacy of the tourniquet in the emergency pre-hospital care setting for the management of haemorrhage. We conducted the systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, the PRISMA statement. We searched the following electronic databases: EMBASE, MEDLINE, and Cochrane-CENTRAL. All studies included were appraised for risk of bias. Prevalent prim…
Clinical and Genetic Aspects of Juvenile Onset Pompe Disease
2021
AbstractLittle is known about clinical symptomatology and genetics of juvenile onset Pompe disease (JOPD). The aims of this study were to analyze how these children are diagnosed, what clinical problems they have, and how phenotype is related to genotype. To accomplish this, we analyzed retrospectively data of 34 patients diagnosed after their first and before completion of their 18th birthday. Median age at diagnosis was 3.9 (range 1.1–17) years. Eight patients (23.5%) developed initial symptoms in the first year, 12 (35%) between 1 and 7 years, and 6 (18%) thereafter. Eight (23.5%) had no clinical symptoms at the time of diagnosis. Indications for diagnostics were a positive family histor…
Scene giudiziarie nelle tragedie e nelle commedie latine del XII e XIII secolo. Il «De Affra et Flavio», il «De Paulino et Polla» di Riccardo da Veno…
2021
La commedia elegiaca e la tragedia latina del XII e XIII secolo mostrano una larga e varia ricchezza di caratteristiche, temi, soggetti e tipologie letterarie: uso del distico elegiaco, "imitatio" ovidiana, preponderanza della tematica amorosa, compresenza di narrazione e dialogo, e così via. Un elemento caratterizzante di alcune di queste commedie e tragedie medievali è rappresentato dalle scene giudiziarie. In questo saggio, dopo una breve introduzione sul genere letterario, viene svolta una puntuale analisi delle scene di giudizio che ricorrono in tre testi latini del XII e XIII secolo, una tragedia (l’anonimo «De Affra et Flavio»), una commedia elegiaca (il «De Paulino et Polla» di Ricc…
Towards Efficient Use of Cement in Ultra High Performance Concrete
2021
Abstract This paper presents an investigation on substituting the cement content with an inert material, in a typical locally produced UHPC mix. A structured literature review was performed to enrichen the discussion and to benchmark the results towards already reported investigations in the research society. Investigations on cement substitution in UHPC are frequently reported. However, usually the cement is substituted with other binding materials – often pozzolanic by-products from other industries. Reports from investigations on the use of inert materials for cement substitution in UHPC seem scarce. An experimental program that included a total of 210 test specimens was executed. This p…
Emergence of the epibiotic barnacle Xenobalanus globicipitis in Guiana dolphins after a morbillivirus outbreak in Sepetiba Bay, Brazil
2021
Abstract We report on the emergence of the epibiotic barnacle Xenobalanus globicipitis in Guiana dolphins (Sotalia guianensis) from Sepetiba Bay, Rio de Janeiro, Brazil, in September 2018, six months after a lethal morbillivirus epidemic. Small boat surveys were conducted at the entrance and in the interior of the bay from January 2018 to February 2021. Dolphins were photo-identified and classified according to overall spatial use of the Bay. We examined the potential influence of the period and habitat on the prevalence of X. globicipitis. The overall prevalence of the barnacle was 38.7% in 214 dolphins. X. globicipitis was not observed in 99 individually identified dolphins from January t…
Economic conditions and populist radical right voting: The role of issue salience
2021
Contains fulltext : 245174.pdf (Publisher’s version ) (Open Access) In this article, we show with the European Election Study from nine Western European countries that issue salience of the economy and immigration contributes to our understanding of the puzzling relation between economic conditions and populist radical right support. In countries with relatively weak or worsening economic conditions, the economy is considered more salient, whereas immigration loses salience – also compared to other issues. Voters who perceive the economy as most important problem are less likely to opt for the populist radical right than people who perceive immigration or even other issues as most important…
Giuseppe Cocchiara, il fascismo e il razzismo
2021
In questo saggio viene ricostruito il rapporto tra Giuseppe Cocchiara e il fascismo. L’antropologo visse in pieno la sua formazione culturale all'interno del regime al quale aderì con convinzione e slancio, militando sempre nelle sue fazioni più radicali, condividendone fedelmente le scelte più tragiche come la guerra d’Etiopia, sottoscrivendo le leggi razziali, impegnandosi nella seconda guerra mondiale con le armi culturali dell’antisemitismo e della lotta senza tregua contro la democrazia. Così quando, come in un «mondo alla rovescia», sconfitto il fascismo sotto il peso di un’umiliante e sanguinosa disfatta, saranno proprio gli odiati inglesi a valorizzarne la statura intellettuale e la…
Bachelor groups form due to individual choices or environmental disrupters in African striped mice
2021
International audience; In several mammal species, bachelor groups occur as a regular life history stage between dispersal and becoming the breeding male of a multi-female group. However, it is rarely investigated how such groups come into existence and how males that choose this strategy differ in life history traits from other males. Males of the socially flexible African striped mouse Rhabdomys pumilio have been historically reported to adopt one of three alternative tactics, i.e., small group-living philopatric males, intermediate solitary living roaming males, or large group-living territorial males. Here, we describe for the first time, bachelors as a fourth male tactic. Using long-te…
Coupled hydro-mechanical analysis of compacted bentonite behaviour during hydration
2021
Abstract This study analyses the response of compacted bentonites upon hydration based on a coupled hydro-mechanical elasto-plastic framework. As an alternative to multi-porosity interpretation, the framework was selected based on the experimental evidence of adsorbed water behaviour in bentonites and the volumetric response at saturated states, apparently independent of its initial state. Based on these premises, a water retention model was formulated using an explicit distinction between adsorbed water and free water, enabling the postulation of the water properties and behaviour depending on its state. In order to effectively account for the transition between unsaturated to saturated st…
The influence of change on sense of coherence on dental services use among adolescents: a two-year prospective follow-up study.
2021
Abstract Background To investigate the influence of change on sense of coherence (SOC) on dental services use in adolescents over a two-year period. Methods A prospective follow-up study was conducted involving 334 12-year-old adolescents from public schools in the city of Manaus, Amazonas, Brazil. The predictors of use of dental services in the last 12 months were selected according to the Andersen’s behavioural theoretical model. The predisposing factors included sex, self-reported skin colour and SOC. The enabling factors were dental insurance, monthly family income and parents/guardians schooling. Dental pain, perceived oral health status, dental caries and gingival status were used to …
I Cannot Place You: Dementia and the Pandemic Experience in The Visiting Hour by Frank McGuinness
2021
This paper presents a new play by Frank McGuinness, a play which was streamed to audiences in April 2021 and published a few weeks later. Set in contemporary Ireland, it focuses on two themes which seem to preoccupy its author: dementia, to which he devoted another play, Hanging Gardens and the consequences of living in a time of Pandemic. In particular, I argue, McGuinness indirectly seems to address an important question: how can literature and theatre offer an opportunity for reflecting about what is happening around us? Can literature help us to better understand and face the world? The play foregrounds the restorative power of emotional authenticity as we see a father and his daughter …
Exploring the mediator role of self-critical rumination between emotion regulation and psychopathology: A validation study of the Self-Critical Rumin…
2021
Abstract Self-critical rumination is a negative and repetitive self-thinking process related to different disorders and negative psychological outcomes such as emotion dysregulation. The objectives of this study are twofold: (a) to examine the factor structure of the Spanish version of the Self-Critical Rumination Scale (SCRS), providing further evidence on its construct validity, and (b), to explore the mediator role of self-critical rumination between emotion dysregulation and psychopathology. A sample of 431 Spanish participants were recruited and completed online questionnaires. Confirmatory factor analysis, mediation analysis, and Pearson's correlations were conducted. A single factor …
Crisi globali, nuove diseguaglianze e co-produzione di spazi: una prospettiva di ricerca
2021
L’articolo propone una riflessione critica sul rischio di negazione sostanziale di diritti di cittadinanza a partire dalle forme di discriminazione nell’uso e fruizione dello spazio pubblico introdotte dalle crisi globali. La co-produzione di nuovi spazi alla micro-scala e alla scala di quartiere (a partire dagli spazi pubblici o semipubblici spesso privatizzati o sottoutilizzati) può divenire l’occasione per la generazione di nuovi luoghi di condivisione e socialità che rispondano alla richiesta di nuovi servizi e definiscano al contempo il profilo di una pratica urbanistica innovativa, fondata sul pieno riconoscimento del diritto alla città e sul patto istituzionicittadini This article pr…
La Valle dei Templi in epoca medioevale. Caratterizzazione antropologica e paleopatologica delle sepolture antistanti in Tempio della Concordia
2021
Riassunto ― Il lavoro presenta i risultati delle analisi bio-archeologiche effettuate su resti scheletrici umani rinvenuti in quattordici sepolture di epoca medioevale rinvenute nel Parco Archeologico della Valle dei Templi di Agrigento (Sicilia). L’obiettivo è stato l’acquisizione delle informazioni necessarie per la ricostruzione del profilo biologico di ciascun individuo, al fine di determinarne il sesso, la stima dell’età biologica alla morte, la stima della statura e la valutazione delle patologie e degli indicatori di stress occupazionale mediante le correnti metodologie e tecniche diagnostiche di tipo antropologico. Sebbene il cattivo stato di conservazione di alcuni individui non ne…
Extension of luminance component based demosaicking algorithm to 4- and 5-band multispectral images
2021
Abstract Multispectral imaging systems are currently expanding with a variety of multispectral demosaicking algorithms. But these algorithms have limitations due to the remarkable presence of artifacts in the reconstructed image. In this paper, we propose a powerful multispectral image demosaicking method that focuses on the G band and luminance component. We've first identified a relevant 4-and 5-band multispectral filter array (MSFA) with the dominant G band and then proposed an algorithm that consistently estimates the missing G values and other missing components using a convolution operator and a weighted bilinear interpolation algorithm based on the luminance component. Using the cons…
Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2
2021
AbstractMost public health measures to contain the COVID-19 pandemic are based on preventing the pathogen spread, and the use of oral antiseptics has been proposed as a strategy to reduce transmission risk. The aim of this manuscript is to test the efficacy of mouthwashes to reduce salivary viral load in vivo. This is a multi-centre, blinded, parallel-group, placebo-controlled randomised clinical trial that tests the effect of four mouthwashes (cetylpyridinium chloride, chlorhexidine, povidone-iodine and hydrogen peroxide) in SARS-CoV-2 salivary load measured by qPCR at baseline and 30, 60 and 120 min after the mouthrinse. A fifth group of patients used distilled water mouthrinse as a contr…
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ
2021
Cancer is characterized by pervasive epigenetic alterations with enhancer dysfunction orchestrating the aberrant cancer transcriptional programs and transcriptional dependencies. Here, we epigenetically characterize human colorectal cancer (CRC) using de novo chromatin state discovery on a library of different patient-derived organoids. By exploring this resource, we unveil a tumor-specific deregulated enhancerome that is cancer cell-intrinsic and independent of interpatient heterogeneity. We show that the transcriptional coactivators YAP/TAZ act as key regulators of the conserved CRC gained enhancers. The same YAP/TAZ-bound enhancers display active chromatin profiles across diverse human t…
Emotional Intelligence Measures: A Systematic Review
2021
Emotional intelligence (EI) refers to the ability to perceive, express, understand, and manage emotions. Current research indicates that it may protect against the emotional burden experienced in certain professions. This article aims to provide an updated systematic review of existing instruments to assess EI in professionals, focusing on the description of their characteristics as well as their psychometric properties (reliability and validity). A literature search was conducted in Web of Science (WoS). A total of 2761 items met the eligibility criteria, from which a total of 40 different instruments were extracted and analysed. Most were based on three main models (i.e., skill-based, tra…