showing 36 of ~574560 from 574555 documents

Varhaiskasvatuksen opettajien käsityksiä mediakasvatuksesta

2021

Tutkimuksessa selvitetään, millaisia käsityksiä varhaiskasvatuksen opettajilla on mediakasvatuksesta. Tutkimusaineisto käsittää yhdeksän varhaiskasvatuksen opettajan teemahaastattelua, ja sen aineisto on analysoitu fenomenografista lähestymistapaa hyödyntäen. Tulokset osoittavat, että varhaiskasvatuksen opettajat käsittävät mediakasvatuksen ensinnäkin toimintana: lasten kanssa toteutettavana toimintana, tavoitteellisena toimintana sekä varhaiskasvatustoimintaan kuuluvana pedagogisena osa-alueena. Mediakasvatuksella käsitetään olevan lasten toimintaan ja toimijuuteen, mediaan liittyviin tietoihin ja taitoihin sekä muuhun oppimiseen liittyviä tavoitteita. Yksikään haastateltavista ei kuitenka…

varhaiskasvatus516 Kasvatustieteetmediakasvatusvarhaiskasvatuksen opettajatVertaisarvioidut artikkelitJournal of Early Childhood Education Research

Recensione di Transizioni metropolitane : declinazioni locali delle dinamiche posturbane in Sicilia

2021

Sono trascorsi quasi vent’anni dalla pubblicazione di Postmetropolis (2000), il libro dell’urbanista statunitense Edward Soja che segnò il definitivo passaggio di testimone dalla scuola di studi urbani di Chicago a quella di Los Angeles. Da qui ripartono gli autori e le autrici di Transizioni postmetropolitane, il volume curato da Francesco Lo Piccolo, Marco Picone e Vincenzo Todaro per Franco Angeli (2018), che si inscrive all’interno del Progetto di Interesse Nazionale 2010-2011 dal titolo “Territori Postmetropolitani come forme urbane emergenti”. L’operazione teorica e analitica che sottende i singoli contributi è ambiziosa e può essere così riassunta: è possibile utilizzare i celebri se…

Transizioni metropolitaneSiciliapostmetropoli

El papel de la autoestima y la soledad en el uso problemático del smartphone: diferencias de género

2021

RESUMEN El presente estudio investigó las relaciones entre la autoestima, la soledad y el uso problemático del smartphone y las diferencias de género. La muestra fue no probabilística y estuvo compuesta por 202 participantes (106 hombres y 96 mujeres), con edades comprendidas entre los 18 y los 58 años, que completaron las siguientes pruebas: Smartphone Addiction Scale, Social and Emotional Loneliness Scale for Adults y Escala de Autoestima de Rosenberg. Se calcularon los estadísticos descriptivos, la prueba U de Mann-Whitney, análisis de correlación bivariados y dos modelos de regresión múltiple jerárquica. Se hallaron diferencias significativas entre hombres y mujeres en el uso problemáti…

soledadself-esteemuso problemático del smartphonegender differencesTelèfon mòbilGeneral Chemical EngineeringlonelinessAutoestimaautoestimadiferencias de géneroproblematic smartphone use

Sport Coaches Burnout as a Threat to Professional Success, Mental Health and Well-Being

2021

The article explores motivational and personality predictors of burnout syndrome in sports coaches. The study involved 183 sports coaches of 20–63 years old (86.9% women; M=41.34±10.56 years), with professional experience for 13.83±9.98 years. Three components of professional burnout ― Emotional exhaustion, Depersonification and Reduction of professional achievements ― were measured with the adapted Maslach professional burnout inventory (Vodopyanova, et al 2008). Motivational aspects were measured with the adapted Ryan and Connell Professional Motivation inventory (Osin et al, 2017). Personal resources ― stress resistance, authenticity and coping strategies ― were measured with the adapted…

resilienssimotivaatioburnoutselviytyminenhyvinvointiRstressiuupumussport psychologyhenkinen hyvinvointiauthenticitymielenterveysmotivationliikuntapsykologiaMedicineGeneral Materials Sciencecoping behaviorvalmentajatresiliencesport coachКлиническая и специальная психология

A Deletion of the Nuclear Localization Signal Domain in the Fus Protein Induces Stable Post-stress Cytoplasmic Inclusions in SH-SY5Y Cells

2021

Mutations in Fused-in-Sarcoma (FUS) gene involving the nuclear localization signal (NLS) domain lead to juvenile-onset Amyotrophic Lateral Sclerosis (ALS). The mutant protein mislocalizes to the cytoplasm, incorporating it into Stress Granules (SG). Whether SGs are the first step to the formation of stable FUS-containing aggregates is still unclear. In this work, we used acute and chronic stress paradigms to study the SG dynamics in a human SH-SY5Y neuroblastoma cell line carrying a deletion of the NLS domain of the FUS protein (homozygous: ΔNLS–/–; heterozygous: ΔNLS+/–). Wild-type (WT) cells served as controls. We evaluated the subcellular localization of the mutant protein through immuno…

amyotrophic lateral sclerosisstomatognathic systemGeneral Neurosciencecytoplasmic inclusionsNeurosciences. Biological psychiatry. NeuropsychiatrySettore MED/26 - Neurologianuclear localization signal (NLS)stress granules (SG)Fused-in-Sarcoma proteinRC321-571NeuroscienceOriginal Research

The Black Mediterranean: A View from Sicily

2021

While Italy has recently experienced nationalist drives, Sicily and in particular the City of Palermo, one of the major ports of refuge for countless migrants arriving in Europe from the African shores, has distinguished itself as an experimental site where to rethink and challenge notions of residence, mobility, citizenship and belonging. Through a series of cultural initiatives, Palermo has become a hub for frontline artists, writers, intellectuals, and activists who have gathered to explore the historically and contemporary ways in which black voices have been silenced and black bodies have been ambiguously imagined in Western-dominated global culture. Investigating these questions is fu…

citizenshipmigrantartistic counter-representationhuman rightfiction as resistance.The Black MediterraneanrefugeeAfrican DiasporabelongingresidencySicilySettore L-LIN/10 - Letteratura Inglese

Ann Radcliffe’s Gothic Romances and the Sea

2021

Biographical materials and the writer’s journals show that Ann Radcliffe had some personal knowledge of the sea and to some extent of sailing. She was also a lover of nature, an enthusiast of 17th -century landscapists, a connoisseur of Pre-Romantic poetry, who was also familiar with contemporary esthetic tastes and theories. In this context, the article analyzes seascapes, maritime and nautical references, motifs of storm and shipwreck in Radcliffe’s Gothic romances, including some poetical lines inspired by the sea with which The Mysteries of Udolpho is interspersed. The writer’s descriptions of the sea and her use of this element in her works are discussed in relation to her fictional ch…

Gothic romancesseascapesAnn Radcliffethe seaExplorations: A Journal of Language and Literature

Deep inelastic scattering off quark-gluon plasma and its photon emissivity

2021

The photon emissivity of quark-gluon plasma probes the interactions in the medium and differs qualitatively between a weakly coupled and a strongly coupled plasma in the soft-photon regime. The photon emissivity is given by the product of kinematic factors and a spectral function associated with the two-point correlator of the electromagnetic current at lightlike kinematics. A certain Euclidean correlator at imaginary spatial momentum can be calculated in lattice QCD and is given by an integral over the relevant spectral function at lightlike kinematics. I present a first exploratory lattice calculation of this correlator. Secondly, I show how Euclidean correlators at imaginary spatial mome…

High Energy Physics::LatticeHigh Energy Physics::PhenomenologyHigh Energy Physics - Lattice (hep-lat)hep-latFOS: Physical scienceshep-phParticle Physics - LatticeLattice QCDHigh Energy Physics - PhenomenologyHigh Energy Physics - LatticeHigh Energy Physics - Phenomenology (hep-ph)Quark-Gluon PlasmaHigh Energy Physics::ExperimentParticle Physics - Phenomenology

Divario territoriale, coesione sociale e tutela dei diritti: il ruolo delle regioni in tempo di crisi

2021

L���articolo si occupa di verificare il ruolo delle regioni in tempo di crisi, finanziaria prima e sanitaria oggi, sia con riferimento alla gestione dell���emergenza pandemica, sia con riguardo alla gestione dei fondi del PNRR, in funzione del difficile tentativo di superare il divario territoriale, e in particolare il divario Nord-Sud, a garanzia di una maggiore protezione dei diritti delle autonomie e dunque della persona.

autonomy regions administrative functions crisis rights protection

Introduction: New Perspectives in Irish Theatre

2021

The text aims to introduce the topics dealt with by all the authors of the volume.

Anglo-Irish Literature and Drama.Settore L-LIN/10 - Letteratura Inglese

false

2021

Nature connectedness is an important factor underlying proenvironmental behavior. Only little is known on the aspects that influence nature connectedness in younger children. The study participants...

Social PsychologyNature connectednessPsychologySocioeconomic statusApplied PsychologyDevelopmental psychologyEcopsychology

Corrigendum to “Bioaccumulation of emerging contaminants in mussel (Mytilus galloprovincialis): Influence of microplastics” [Sci. Total Environ. 796 …

2021

MicroplasticsEnvironmental EngineeringbiologyEnvironmental chemistryBioaccumulationEnvironmental ChemistryEnvironmental scienceMusselContaminationbiology.organism_classificationPollutionWaste Management and DisposalMytilusScience of The Total Environment

Burnout syndrome assessment among Spanish oral surgery consultants: A two populations comparative pilot study.

2021

Background The professional Burnout Syndrome (BOS) or Burnout is considered a professional disease made up of three interrelated dimensions (emotional exhaustion, depersonalization and lack of personal fulfillment). BOS has been documented to most severely affect the healthcare professions, especially dentists. On the other hand, its appearance has been documented at an early age, during dental training. However, there are no studies that analyze its incidence in professionals dedicated to Oral Surgery and Implantology, determining the age of onset and related factors. Material and Methods The modified Maslach questionnaire was carried out anonymously among the professors and students of th…

tongue lesionsConsultantsallergiesResearcheducationOral Surgical ProceduresPilot Projects610 Medicine & healthfissured tonguesystemic diseasesmedicationsOtorhinolaryngologyChild PreschoolSurveys and QuestionnairesHumansrisk factorsSurgeryOral Surgery610 Medicine & healthGeneral DentistryBurnout ProfessionalUNESCO:CIENCIAS MÉDICAS

The Synbiotic Combination of Akkermansia muciniphila and Quercetin Ameliorates Early Obesity and NAFLD through Gut Microbiota Reshaping and Bile Acid…

2021

Gut microbiota plays a key role in obesity and non-alcoholic fatty liver disease (NAFLD), so synbiotics could be a therapeutic alternative. We aim to evaluate a nutritional intervention together with the administration of the bacteria Akkermansia muciniphila and the antioxidant quercetin in an in vivo model of early obesity and NAFLD. 21-day-old rats were fed with control or high-fat diet for six weeks. Then, all animals received control diet supplemented with/without quercetin and/or A. muciniphila for three weeks. Gut microbiota, NAFLD-related parameters, circulating bile acids (BAs) and liver gene expression were analyzed. The colonization with A. muciniphila was associated with less bod…

gut microbiotaPhysiologysynbioticClinical BiochemistryRM1-950Cell BiologyBiochemistrydigestive system<i>Akkermansia muciniphila</i>; childhood obesity; gut microbiota; quercetin; synbioticArticlequercetinTherapeutics. Pharmacologychildhood obesityMolecular BiologyAkkermansia muciniphila<i>Akkermansia muciniphila</i>Antioxidants; Volume 10; Issue 12; Pages: 2001

Integration of large-area optical imagers for biometric recognition and touch in displays

2021

In recent years there has been an increasing interest to integrate optical sensing in mobile displays, for instance, for biometric fingerprint scanning functionality. There are several routes to incorporate optical fingerprint functionality within the full display area, each with their own benefits and challenges. Here we investigate the different integration routes using large-area, ultra-thin imagers based on organic photodiodes.

display integrationbiometricsMaterials scienceBiometricsgenetic structuresbusiness.industrylarge-area imagerComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONFingerprint recognitionfingerprint scannerAtomic and Molecular Physics and Opticseye diseasesElectronic Optical and Magnetic MaterialsAMOLEDAMOLEDComputer visionArtificial intelligencesense organsElectrical and Electronic Engineeringbusinessoptical sensorOPDorganic photodiodeJournal of the Society for Information Display

Primi risultati sulla disidratazione del mango siciliano: un prodotto nuovo che fa bene alla salute

2021

Prendendo spunto dall’essiccazione al sole, tecnica antica legata alla nostra tradizione utilizzata per conservare a lungo frutti e ortaggi, abbiamo disidratato il mango siciliano in corrente di aria calda, ottenendo un prodotto nuovo, naturale, ricco di colore, aroma e gusto

Mango Mangifera indica frutta disidratata qualità dei frutti frutta tropicale

Chutzpadik advertising and its effectiveness: Four studies of agencies and audiences

2021

Abstract The creation of advertisements that attract immediate attention and simultaneously provoke thoughts and stimulate ongoing discussions is challenging. Hence, advertisers increasingly use Chutzpadik advertising, which we define as “radical advertising messaging that purposefully transgresses social norms and proscribed topics”. We conduct four studies to identify the dimensions and evaluate the effectiveness of Chutzpadik advertising. The first two studies involve interviews with 12 managers of advertising agencies and 22 members of the Israeli general public (audience members). The interviews reveal Chutzpadik advertising’s dimensions are norm violation, novelty, and audacity. In tw…

MarketingAdvertising researchQualitative comparative analysisVDP::Social science: 200::Economics: 210NoveltyAdvertisingNorm (social)Affect (psychology)PsychologyStructural equation modeling

The Effect of Postoperative Complications After Minimally Invasive Esophagectomy on Long-term Survival: An International Multicenter Cohort Study

2021

Item does not contain fulltext BACKGROUND: Esophagectomy is a technically challenging procedure, associated with significant morbidity. The introduction of minimally invasive esophagectomy (MIE) has reduced postoperative morbidity. OBJECTIVE: Although the short-term effect on complications is increasingly being recognized, the impact on long-term survival remains unclear. This study aims to investigate the association between postoperative complications following MIE and long-term survival. METHODS: Data were collected from the EsoBenchmark Collaborative composed by 13 high-volume, expert centers routinely performing MIE. Patients operated between June 1, 2011 and May 31, 2016 were included…

medicine.medical_specialtySurvivalmedicine.medical_treatmentPostoperative complications03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingmedicineClinical endpointMinimally invasive esophagectomybusiness.industryIncidence (epidemiology)Organ dysfunctionHazard ratioEsophageal cancermedicine.diseaseSurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Esophagectomy030220 oncology & carcinogenesis030211 gastroenterology & hepatologySurgerymedicine.symptomComplicationbusinessCohort study

Transcriptomic autophagy-related gene signature investigation for type 2 diabetes in Mediterranean subjects

2021

Abstract Background Autophagy (involving degradation and clearance of damaged organelles and compounds) plays a role in type 2 diabetes (T2D). There are three main types of autophagy and several genes involved. These genes have been well studied in animal models, but there are few transcriptomic studies in humans. Our aim is to analyze the differential gene expression, and the functional enrichment of the main autophagy-related genes (ARG) in T2D subjects from a Mediterranean population Methods We analyzed 120 White-European subjects (mean age 61,4 years; 50% women; 24 T2D) from Valencia, Spain. Clinical and lifestyle data were obtained. ARN was isolated from blood. Transcriptome-wide gene …

Geneticseducation.field_of_studybusiness.industryPopulationUVRAGFold changeGene expressionGene chip analysisMedicineKEGGCardiology and Cardiovascular MedicineeducationbusinessGeneATG16L1American Heart Journal

Extension of luminance component based demosaicking algorithm to 4- and 5-band multispectral images

2021

Abstract Multispectral imaging systems are currently expanding with a variety of multispectral demosaicking algorithms. But these algorithms have limitations due to the remarkable presence of artifacts in the reconstructed image. In this paper, we propose a powerful multispectral image demosaicking method that focuses on the G band and luminance component. We've first identified a relevant 4-and 5-band multispectral filter array (MSFA) with the dominant G band and then proposed an algorithm that consistently estimates the missing G values and other missing components using a convolution operator and a weighted bilinear interpolation algorithm based on the luminance component. Using the cons…

Computer engineering. Computer hardwareDemosaicingDemosaicking algorithmComputer scienceMultispectral imageBilinear interpolationQA75.5-76.95General MedicineExtension (predicate logic)Filter (signal processing)Multispectral filter arrayLuminanceConvolutionTK7885-7895G bandElectronic computers. Computer scienceComponent (UML)Weighted bilinear interpolationLuminance componentAlgorithmArray

Quick determination of Glyphosate and AMPA at sub µg/L in drinking water by direct injection into LC-MS/MS

2021

Abstract A sensitive, simple and quick method for the determination of glyphosate (Gly) and its degradation product, Aminomethyl phosphonic acid (AMPA), in water through ion chromatography coupled to quadrupole-linear ion trap mass spectrometry has been developed. Sample treatment was based on direct injection and acquisition was implemented in both MS2 and MS3 modes. The LoQs of the method were 0.03 µ/L for both Gly-and AMPA. The recoveries were between 91 and 118% and RSD was lower than 15%. The developed methodology was applied on 436 water samples.

ChromatographyQD71-142ChemistryMass spectrometry 4Ion chromatographyLiquid chromatography 3Water 2AMPA receptorGlyphosate 1chemistry.chemical_compoundGlyphosateLc ms msAnalytical chemistryIon trap mass spectrometryTalanta Open

Coupled hydro-mechanical analysis of compacted bentonite behaviour during hydration

2021

Abstract This study analyses the response of compacted bentonites upon hydration based on a coupled hydro-mechanical elasto-plastic framework. As an alternative to multi-porosity interpretation, the framework was selected based on the experimental evidence of adsorbed water behaviour in bentonites and the volumetric response at saturated states, apparently independent of its initial state. Based on these premises, a water retention model was formulated using an explicit distinction between adsorbed water and free water, enabling the postulation of the water properties and behaviour depending on its state. In order to effectively account for the transition between unsaturated to saturated st…

Materials scienceSettore ICAR/07 - GeotecnicaUnsaturated soilsDegree of saturationEffective stressConstitutive equationThermodynamicsWater retentionGeotechnical Engineering and Engineering GeologyBentonite Elasto-plasticity Hydro-mechanical couplings Unsaturated soils Water retentionComputer Science ApplicationsWater retentionStress (mechanics)BentoniteBentonitemedicineCompressibilityHydro-mechanical couplingsElasto-plasticitymedicine.symptomSaturation (chemistry)Computers and Geotechnics

Use of stevia and chia seeds for the formulation of traditional and vegan artisanal ice cream

2021

Abstract Gelato is the name of the Italian-style artisanal ice cream, a nutritious product widely consumed in different parts of the world. Due to the high content in simple sugars, ice cream should be consumed moderately by diabetic patient. This research aimed to create artisanal ice cream, using Stevia rebaudiana, a plant well known for its sweet taste and its hypoglycemic effect. Traditional and vegan ice cream were formulated using stevia and chia seeds, in order to obtain products with appreciable rheological, textural and sensorial properties. Physical and sensorial properties of the ice cream formulation containing milk protein (traditional) or vegan substitute, were evaluated. Resu…

Cultural StudiesIce creamSensoryMilk proteinbiologyChia seedHeavy metalsSweet tasteSettore AGR/15 - Scienze E Tecnologie Alimentaribiology.organism_classificationSteviaChia seedsStevia rebaudianaFormulationIce creamSteviaFood scienceTextureDiabetic patientFood ScienceMathematics

Why and how to use enterprise social media platforms: The employee’s perspective

2021

Abstract Literature supports the relevance of knowledge sharing in a company. Considering that social media plays an important role in this process, this paper analyzes the antecedents and consequences of the use of enterprise social media platforms according to the employee's perception. Based on the Motivation-Opportunity-Ability framework and using two different methodologies (Partial Least Squares Structural Equation Modeling and fuzzy-set Qualitative Comparative Analysis), we find that three different combinations of motivation, opportunity and ability factors, combined in pairs, promote the use of enterprise social media platforms, leading to knowledge creation and task performance. T…

MarketingKnowledge managementbusiness.industryProcess (engineering)Qualitative comparative analysismedia_common.quotation_subjectPerspective (graphical)Structural equation modelingKnowledge sharingPerceptionSocial mediaRelevance (information retrieval)businessmedia_commonJournal of Business Research

Temporal turnover of the soil microbiome composition is guild-specific.

2021

Although spatial and temporal variation are both important components structuring microbial communities, the exact quantification of temporal turnover rates of fungi and bacteria has not been performed to date. In this study, we utilised repeated resampling of bacterial and fungal communities at specific locations across multiple years to describe their patterns and rates of temporal turnover. Our results show that microbial communities undergo temporal change at a rate of 0.010-0.025 per year (in units of Sorensen similarity), and the change in soil is slightly faster in fungi than in bacteria, with bacterial communities changing more rapidly in litter than soil. Importantly, temporal deve…

0106 biological sciencesLITTERBACTERIALSPATIAL VARIABILITYDIVERSITYBiologyFUNGAL COMMUNITIES010603 evolutionary biology01 natural sciences03 medical and health sciencesforestSoilTemporal changeMicrobiomeBacterial phylabacteriaEcology Evolution Behavior and SystematicsSCALESoil Microbiology030304 developmental biology0303 health sciencesNITROGEN DEPOSITIONECTOMYCORRHIZAL FUNGIEcologyMicrobiotaFungi15. Life on landMicrobial population biologyOAKGuild1181 Ecology evolutionary biologyLittertemporal turnovercommunity assemblyRESPONSESMycobiomeEcology lettersREFERENCES

Minori di età e formazione dei giovani atleti : storia di una riforma incompiuta

2021

The paper analyses the recent reform of the Italian sport system that includes, for the first time, some new regulations about minors and young athletes. The work underlines that despite the attempt by the legislator, the result is still not satisfying due to the lack of a 'child-centred' perspective.

MinorSettore IUS/01 - Diritto Privatorights of minorsport reformchild- entered perspectiveCRC

Healthy ageing and Mediterranean diet: A focus on hormetic phytochemicals

2021

Abstract Mediterranean diet (MedDiet) is rich in fruits and vegetables associated with longevity and a reduced risk of several age-related diseases. It is demonstrated that phytochemicals in these plant products enhance the positive effects of MedDiet by acting on the inflammatory state and reducing oxidative stress. Evidence support that these natural compounds act as hormetins, triggering one or more adaptive stress-response pathways at low doses. Activated stress-response pathways increase the expression of cytoprotective proteins and multiple genes that act as lifespan regulators, essential for the ageing process. In these ways, the hormetic response by phytochemicals such as resveratro…

AgingMediterranean dietmedia_common.quotation_subjectLongevityPhytochemicalsResveratrolBiologymedicine.disease_causeDiet MediterraneanHealthy Agingchemistry.chemical_compoundHormesisStress PhysiologicalMediterranean dietmedicineHumansFood sciencemedia_commonCellular stress-response pathwaysAgeing; Cellular stress-response pathways; Hormesis; Mediterranean diet; PhytochemicalsLow doseHormesisLongevityAgeingchemistryAgeingHealthy ageingOxidative stressDevelopmental Biology

Promoting a Syndemic Approach for Cardiometabolic Disease Management During COVID-19: The CAPISCO International Expert Panel

2021

Efforts in the fight against COVID-19 are achieving success in many parts of the world, although progress remains slow in other regions. We believe that a syndemic approach needs to be adopted to address this pandemic given the strong apparent interplay between COVID-19, its related complications, and the socio-structural environment. We have assembled an international, multidisciplinary group of researchers and clinical practitioners to promote a novel syndemic approach to COVID-19: the CArdiometabolic Panel of International experts on Syndemic COvid-19 (CAPISCO). This geographically diverse group aims to facilitate collaborative-networking and scientific exchanges between researchers and …

diabetescomplicationsRC666-701pandemicPerspectivesyndemicDiseases of the circulatory (Cardiovascular) systemCOVID-19Cardiovascular MedicineCardiology and Cardiovascular Medicinecardiovascular diseasesFrontiers in Cardiovascular Medicine

GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data

2021

AbstractBackgroundThe interpretation of results from transcriptome profiling experiments via RNA sequencing (RNA-seq) can be a complex task, where the essential information is distributed among different tabular and list formats - normalized expression values, results from differential expression analysis, and results from functional enrichment analyses. A number of tools and databases are widely used for the purpose of identification of relevant functional patterns, yet often their contextualization within the data and results at hand is not straightforward, especially if these analytic components are not combined together efficiently.ResultsWe developed the GeneTonic software package, whi…

QH301-705.5Process (engineering)Computer scienceShinyComputer applications to medicine. Medical informaticsBioconductor610 MedizinR858-859.7Context (language use)Interactive data analysisReproducible researchBioconductorInteractivity610 Medical sciencesUse caseRNA-SeqBiology (General)MIT LicenseTranscriptomicsInformation retrievalBase SequenceSequence Analysis RNAData interpretationData visualizationRReproducibility of ResultsIdentification (information)WorkflowRNASoftwareFunctional enrichment analysis

Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis treatment and follow-up of patients with localised colon cancer

2021

The most recent version of the European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of localised colon cancer was published in 2020. It was decided by both the ESMO and the Japanese Society of Medical Oncology (JSMO) to convene a special virtual guidelines meeting in March 2021 to adapt the ESMO 2020 guidelines to take into account the ethnic differences associated with the treatment of localised colon cancer in Asian patients. These guidelines represent the consensus opinions reached by experts in the treatment of patients with localised colon cancer representing the oncological societies of Japan (JSMO), China (CSCO), India (…

medicine.medical_specialtyAsiaColorectal cancerDrug availabilityEthnic grouplocalised colon cancerMedical OncologyScientific evidenceFollow-Up StudieRepublic of KoreaAsian countryMedicineReimbursementColonic NeoplasmPan-Asiantreatmentbusiness.industryHematologyESMOmedicine.diseaseClinical PracticediagnosiOncologyDiagnosis treatmentFamily medicinebusinessguidelineHuman

La Sicilia dei centri minori: Above the clouds nella Valle di Bolognetta : architettura, arti performative e nuovi immaginari

2021

Il lavoro elaborato dal Gruppo di ricerca LabCity Architecture sulla rigenerazione dei piccoli centri rurali del territorio siciliano, vittime della crisi economica e demografica di quest’ultimo decennio, evidenzia l’urgenza di un ripensamento delle strategie di intervento in questi luoghi con forti potenzialità territoriali, patrimoniali e culturali, proponendo progetti di ricerca-azione in sinergia con le comunità locali coinvolte. La recente emergenza sanitaria causata dalla pandemia da Covid-19 ha evidenziato l’esigenza di una ricerca mirata ad individuare i caratteri e le esigenze specifiche soprattutto dei centri minori, destinatari di politiche e di interventi spesso inadeguati. In q…

architettura temporanea centri minori rigenerazione Valle di Bolognetta workshop di progettazione architettonicatemporary architecture small town regeneration Valley of Bolognetta architecture design workshopSettore ICAR/14 - Composizione Architettonica E Urbana

Sociodemographic factors associated with time to discharge for hospitalised patients with asthma and asthma exacerbation using the Ghana Health Servi…

2021

ObjectiveData on asthma hospitalisations are a useful source of patient morbidity information. In Ghana, the length of stay (LoS) and sociodemographic factors of patients hospitalised for asthma and its exacerbation are understudied. We aimed to investigate the time to discharge and assessed factors associated with length of hospital stays of asthmatics in Ghana.MethodsRetrospective analysis of hospitalised patient with asthma records between 2012 and 2017 from the nationwide Ghana Health Service District Health Information Management System 2 database. We calculated the cumulative incidence function for discharge stratified by age group and sex. Multivariable Cox regression was used to inv…

Pulmonary and Respiratory MedicineAdultSociodemographic FactorsExacerbationInformation Managementcomputer.software_genreGhanaHealth servicesDiseases of the respiratory systemHealth caremedicineHumans1506ChildEarly dischargeAsthmaRetrospective StudiesAsthma exacerbationsDatabaseRC705-779business.industryProportional hazards modelasthma epidemiologyRmedicine.diseaseComorbidityAsthmaPatient DischargeCOPD exacerbationsMedicineFemalebusinesscomputerBMJ Open Respiratory Research

The role of shame and guilt in social anxiety disorder

2021

Abstract Research suggests that shame and guilt may play a role in anxiety disorders. For social anxiety disorder (SAD), however, only a few studies investigated patients with the primary diagnosis of SAD. Thus, further research on shame and guilt in SAD is required. A secondary analysis of Data from the SOPHO-NET multicenter treatment study was performed. In a large sample of N = 495 patients with the primary diagnosis of SAD the relationship between shame and guilt with symptoms of social anxiety, depression, and interpersonal problems was examined by means of correlation analysis and additionally, a hierarchical linear regression analysis. To assess SAD, the German version of the Structu…

media_common.quotation_subjecteducationShameShameAffect (psychology)behavioral disciplines and activities03 medical and health sciencesInterpersonal relationship0302 clinical medicineSecondary analysismental disordersmedicineSocial anxiety disorderRZ400-408Depression (differential diagnoses)media_commonSocial anxiety030227 psychiatryCorrelation analysisGuiltbehavior and behavior mechanismsAnxietymedicine.symptomPsychologyMental healingpsychological phenomena and processes030217 neurology & neurosurgeryClinical psychologyJournal of Affective Disorders Reports

Frequency dynamics of power systems with temporally distributed disturbances

2021

Abstract The frequency dynamics and stability of power systems is essentially affected by nature and characteristics of the disturbances occurring in the system. Conventionally, frequency transients are examined assuming a single disturbance applied at a given time. However, actual incidents in the power systems can be generally composed of a temporal sequence of events, and thus characterized by multiple power imbalances of different magnitudes and time offsets. The consideration of the effects of the temporal distribution of power imbalances is important for two main reasons: the impact on the frequency dynamics of the system in terms of frequency metrics such as minimum instantaneous fre…

Primary frequency controlRenewable Energy Sustainability and the EnvironmentComputer scienceWork (physics)Energy Engineering and Power TechnologyDistributed powerStability (probability)Instantaneous phasePower (physics)Settore ING-IND/33 - Sistemi Elettrici Per L'EnergiaElectric power systemControl and Systems EngineeringControl theorySystem splitTransient (oscillation)Electrical and Electronic EngineeringRepresentation (mathematics)Power imbalancePower system dynamicFrequency transientSustainable Energy, Grids and Networks

The effect of staining and bleaching on the color of two different types of composite restoration

2021

Background Long term success of composite restorations depends greatly on their color stability and esthetic appearance. This study aimed to assess the effects of commonly consumed beverage and bleaching on the color of composite restoration. Material and Methods Two resin composite were used Filtek™ Z350 XT (3M/ESPE) and Briliant EverGlow (Coltene). Fifteen discs were made from each resin composite then baseline color measurements were made. The specimens divided into 3 groups (n=5) according to the storage solution. The storage solutions that used in this study are distilled water, tea and coffee. The specimens were stored in the solutions for 3h/day for 40 days and then second color meas…

genetic structuresResearchsense organsEsthetic DentistryGeneral DentistryUNESCO:CIENCIAS MÉDICAS

Giovanni Marrasio fra Virgilio, Orazio e Properzio

2021

Questo saggio mira a presentare la figura e l’opera poetica di Giovanni Marrasio (Noto, 1400/1404 - Caltanissetta, sett. 1452), umanista siciliano autore dell’«Angelinetum» e dei «Carmina varia», attivo nella prima metà del sec. XV fra la Sicilia e Siena, Firenze e Padova, Ferrara e Napoli, in rapporti con altri umanisti e letterati (Giovanni Aurispa, Antonio Beccadelli, Leonardo Bruni, Enea Silvio Piccolomini, Carlo Marsuppini, Maffeo Vegio, Niccolò Niccoli, Guarino Veronese), potenti uomini di stato (Niccolò III d’Este, Alfonso il Magnanimo) e di chiesa (papa Niccolò V). In particolare, la disamina si concentra sulle suggestioni che Virgilio, Orazio e Properzio hanno esercitato sulla poes…

Settore L-FIL-LET/08 - Letteratura Latina Medievale E UmanisticaHoracePropertiuHumanistic ImitationLove PoetryGiovanni MarrasioVergilClassical TraditionSettore L-FIL-LET/13 - Filologia Della Letteratura Italiana