showing 36 of ~574560 from 574555 documents
Bone damage after chemotherapy for lymphoma: a real-world experience
2021
AbstractBackgroundDespite recent improvements in survival due to advances in treatment, the quality of life of patients with lymphoma may be compromised by the long-term complications of chemotherapy and steroid therapy. Among these, a potentially relevant problem is bone loss and the development of fragility fractures.AimTo provide further evidence of clinical or subclinical skeletal complications in correlation with biological variables and markers of bone disease in patients with complete response to therapy.MethodA cross-sectional observational study was conducted on subjects diagnosed with lymphoma with subsequent antineoplastic treatment, disease status after therapy defined as comple…
Digital Pathology Enables Automated and Quantitative Assessment of Inflammatory Activity in Patients with Chronic Liver Disease
2021
Traditional histological evaluation for grading liver disease severity is based on subjective and semi-quantitative scores. We examined the relationship between digital pathology analysis and corresponding scoring systems for the assessment of hepatic necroinflammatory activity. A prospective, multicenter study including 156 patients with chronic liver disease (74% nonalcoholic fatty liver disease-NAFLD, 26% chronic hepatitis-CH etiologies) was performed. Inflammation was graded according to the Nonalcoholic Steatohepatitis (NASH) Clinical Research Network system and METAVIR score. Whole-slide digital image analysis based on quantitative (I-score: inflammation ratio) and morphometric (C-sco…
The role of shame and guilt in social anxiety disorder
2021
Abstract Research suggests that shame and guilt may play a role in anxiety disorders. For social anxiety disorder (SAD), however, only a few studies investigated patients with the primary diagnosis of SAD. Thus, further research on shame and guilt in SAD is required. A secondary analysis of Data from the SOPHO-NET multicenter treatment study was performed. In a large sample of N = 495 patients with the primary diagnosis of SAD the relationship between shame and guilt with symptoms of social anxiety, depression, and interpersonal problems was examined by means of correlation analysis and additionally, a hierarchical linear regression analysis. To assess SAD, the German version of the Structu…
Gli spazi dell'apprendimento. La scuola all'aperto
2021
L'articolo sintetizza le diverse possibilità di realizzare un modello di scuola all'aperto, tra idee esistenti da decine d'anni e nuove esigenze e tendenze. Il tema non nuovo ma reso attuale dalla situazione attuale, che sta spingendo molte scuole ad organizzare ed immaginar nuovi spazi, non senza innovare anche il modo di fare didattica.
Attraversare l’inatteso selvatico urbano. Un’esperienza di cammino con Stalker a Roma est
2021
Italian cities have undergone in the past century a rapid development which has generated abandoned areas within its limits. Many of these places are now uncultivated and rich in spontaneous vegetation. The article reports the relationship between a wild area in eastern Rome, the ex-SNIA-Viscosa Lake, from which the artistic group Stalker has started some walking experiences. During the crossing of the wild spaces that characterize this part of the city, questions emerged related to the link between a community and unpredictable nature, the search for new approaches to conservation and the planning of natural spaces in the city.
Clinical profiles and quality of care of adults with type 1 diabetes according to their cardiovascular Risk: A Multicenter, Observational, retrospect…
2021
Abstract Aims The European Society of Cardiology (ESC) recently defined cardiovascular risk classes for subjects with diabetes. Aim of this study was to explore the distribution of subjects with type 1 diabetes (T1D) by cardiovascular risk groups according to the ESC classification and to describe the quality indicators of care. Methods The study is based on data extracted from electronic medical records of patients treated at the 258 Italian diabetes centers participating in the AMD (Associazione Medici Diabetologi) Annals initiative. Patients with T1D were stratified by cardiovascular risk. Measures of intermediate outcomes, intensity/appropriateness of pharmacological treatment, and over…
One coast, two systems: Regional innovation systems and entrepreneurial discovery in Western Norway
2021
This paper introduces an analytical framework for understanding how specialized and diversified regional innovation system (RIS) differ in the way an entrepreneurial discovery process (EDP) is likely to unfold. To analytically explore the proposed framework, we deploy a sequential explanatory design approach, using quantitative data to analyze the regional industry structure of the city regions of Bergen and Stavanger in Western Norway, followed by a qualitative analysis of interviews with key stakeholders in both regions. We find that the city regions face unique challenges that align with an understanding of their respective RIS categorization, providing evidence that the framework propos…
Patrimonio storico minore e nuove forme dell'abitare
2021
Si tratta dell'estratto di una ricerca nazionale coordinata dal Prof. Alberto Ferlenga sul Parco transfrontaliero del Natisone, caratterizzato quest'ultimo dalla presenza di piccoli borghi e di architetture tradizionali – edifici rurali, mulini, rovine di fortificazioni militari e muretti a secco – costruiti lungo il fiume. Alcuni interventi di piccola dimensione a scala architettonica, ma legati a processi di riqualificazione urbana, vengono qui proposti come dispositivi necessari per potenziare la fruizione turistica della parte montana della valle del Natisone. Una sperimentazione che si pone l’obiettivo di recuperare e valorizzare alcuni ambiti con un carattere tradizionale riconoscibil…
Palermo e il Piano Programma: morfologia e fenomenologia urbana
2021
Il presente contributo parte dall’ipotesi che particolari condizioni contestuali (fisiche e culturali) dei luoghi possano strutturalmente condizionare le specifiche modalità di lettura e di conoscenza nei diversi approcci al progetto (a partire dal periodo di formazione degli architetti). La città di Palermo è introdotta come ambito di riferimento, fisico e culturale, rispetto al quale una particolare assunzione dei temi della morfologia urbana ha consentito, soprattutto grazie all’azione di Giuseppe Samonà, la definizione del “Piano Programma per il Centro Storico di Palermo”: un interessante esperimento di pianificazione, per molti aspetti ancora attuale, in cui analisi e progetto tendono…
Includere per apprendere, apprendere per includere. Formazione e sviluppo professionale inclusivo degli insegnanti.
2021
La prospettiva inclusiva se da una parte ha portato a nuovi modelli che sono più complessi e spesso richiedono cambiamenti difficili ai modi di funzionamento tradizionale delle scuole, dall’altra si pone come uno scenario stimolante ed intrinsecamente ricco di opportunità a partire da quel che appartiene al campo professionalità dei docenti. Il volume muove dall’idea che il concetto di inclusione, che cresce e si consolida non nell’ottica della pedagogia dell’emergenza, ma come una pedagogia dell’accoglienza e della consapevolezza, richiede un cambiamento di paradigma a partire dagli elementi che caratterizzano la formazione e la professionalità degli insegnanti. In questa direzione la dida…
Cognitive Systems Research: Special Issue on Biologically Inspired Cognitive Architectures: Papers from the Tenth Annual International Conference on …
2021
This Special Issue of Cognitive System Research on Biologically Inspired Cognitive Architectures: Papers from the Tenth Annual International Conference on Biologically Inspired Cognitive Architectures (BICA 2019) have solicited and collected research papers in all domains of science and technology that directly or indirectly may help us to make an advance toward the BICA Challenge, which is to implement the top essential functionality of the human mind in a machine. The selected papers included here are based on presentations given from 16 to 18 August 2019 during the 10th Annual International Conference on Biologically Inspired Cognitive Architectures (BICA 2019) held at the Microsoft Main…
Luca Matranga e il suo tempo storico
2021
This volume collects the proceedings of the XXX International Conference of Albanology organized by the Department of Cultures and Society and held on 5 and 6 May 2019 in Palermo and in the two Sicilian Albanian communities of Piana degli Albanesi and Santa Cristina Gela. The meeting was wanted both to inaugurate the Departmental Laboratory of Albanology on the occasion of the fourth centenary of the death of the author of the first book in Arbëresh, Luca Matranga (18 January 1569 - 6 May 1619), and to deepen the knowledge of a complex period of the cultural history of the Albanians, both of those who for centuries settled in southern Italy and of the others who reside on the eastern shores…
Pandemia in translation: a comparative understanding of European social values
2021
This volume, resulting from the training and research activities of the “Pandemic in translation” project – FORTHEM’s Experiencing Europe Lab, University of Palermo –, deals with central issues related to COVID-19 pandemic, and aims at contributing to a comparative understanding of mainly, but not exclusively European values challenged during this contingency. This interdisciplinary projects mobilizes a multicultural and multilingual debate about norms and beliefs, cultural identities and societal values, public policies and emotional communities. Using methodologies drawn from Comparative and International Law to Comparative Literature, from discourse analysis to Translation Studies, this …
The submerged syntax between Late Antiquity and the Modern Age. Sources, models, and interpretative strategies
2021
The present volume contains selected papers from the international conference on “The submerged syntax between Late Antiquity and the Modern Age. Sources, models, and interpretative strategies”, that took place in Palermo, 28-29 November 2019, hosted by the Department of Humanities at the University of Palermo. The conference was organized under the umbrella of a project of national relevance funded by the Italian Ministry of Education, University and Research, named “Parts of speech meet rhetorics: searching for syntax in the continuity between the Middle Ages and the Modern Age” (PRIN 20172F2FEZ, March 2017).
Cities' identity and urban redevelopment: a study for the enhancement of self-built houses
2021
The study objective is the knowledge of the ways in which ‘the universe of the house is structured’ , in particular in a selected neighbourhood located on the northern edge of Favara - a town in the Sicilian hinterland, few kilometres far from Agrigento - characterized by self-building. The hope is that the investigated built-up heritage, together with public open spaces, can be recovered and enhanced by the community and local governance through strategic urban redevelopment actions not to lose a significant part of the city’s identity and history.
Fungal Contaminants and Mycotoxins in Nuts
2021
Contamination by fungi and mycotoxins in nuts has achieved much attention in recent years. In fact, the fungal metabolites produced by the species of Aspergillus, Penicillium (aflatoxins and ochratoxins), Fusarium (trichothecenes, zearalenones and fumonisins) and Alternaria (alternariotoxins) with toxic and/or carcinogenic effects are considered a threat to human and animal health. In this chapter we will discuss the main fungal taxa and related mycotoxins most frequently associated with these materials. In this regard, the first results on the level of contamination by fungi and mycotoxins in samples of almonds and pistachios of different origins will be reported. The main strategies to re…
Le aziende vitivinicole. Scritti vari - Parte seconda - Un approccio economico aziendale
2021
The book contains some articles and contributions written in the latest 30 years concerning all fileds and all functions of the modern regional companies wineries.
Proscribing the Nordic Resistance Movement in Finland: Analyzing the Process and its Outcome
2021
The Nordic Resistance Movement (NRM) was banned in Finland in 2020 after a court process lasting more than two and half years. This article details how effective the ban has been and how the organization has adapted to the ban, both during the process and after the verdict. The NRM has followed strategies similar to previous proscription cases, especially National Action in the UK in 2016, with whom NRM members discussed and shared experiences before the banning process began. Adaptation has meant new organizational forms and the founding of new associations. Before the ban, some commentators argued that it would only radicalize NRM members and that they might move to clandestine actions. B…
Maus: la geografia sociale nel mondo dei fumetti
2021
This contribution discusses Art Spiegelman's most famous graphic novel, Maus, in the light of social geography studies.
Myoglobin, expressed in brown adipose tissue of mice, regulates the content and activity of mitochondria and lipid droplets
2021
Abstract The identification of novel physiological regulators that stimulate energy expenditure through brown adipose tissue (BAT) activity in substrate catalysis is of utmost importance to understand and treat metabolic diseases. Myoglobin (MB), known to store or transport oxygen in heart and skeletal muscles, has recently been found to bind fatty acids with physiological constants in its oxygenated form (i.e., MBO2). Here, we investigated the in vivo effect of MB expression on BAT activity. In particular, we studied mitochondrial function and lipid metabolism as essential determinants of energy expenditure in this tissue. We show in a MB-null (MBko) mouse model that MB expression in BAT i…
Plantar pressure distribution during running with a self-customized foot orthosis in a home microwave.
2021
The individualization of a custom-made foot orthosis could provide improvements in plantar loading distribution regarding a prefabricated one. However, not all runners can afford it because of its high cost. A new type of low-cost prefabricated foot orthoses with self-customization could be the solution. The aim of the study was to evaluate if self-customized prefabricated foot orthoses (SCFO) could improve plantar pressure distribution with respect to generic prefabricated ones without customization, during the intense prolonged running. Thirty healthy recreational runners performed two tests of 30 min running on a treadmill, each one with a foot orthosis condition, on different days. Mean…
On Defining the Participatory Museum: The Case of the Museum of the Second World War in Gdansk
2021
This article seeks to contribute to the current debate on the new definition of the “museum” – a debate which led to turmoil at the 2019 ICOM General Assembly in Kyoto. With reference to the case study of the Museum of the Second World War in Gdansk (MSWW), it analyses the new and very successful genre of the narrative museum, a genre which arguably fulfils the core elements of the definition currently being discussed by ICOM. In this regard, it brings into focus the paramount importance of community involvement in creating and managing narrative museums – an aspect that has been virtually absent in the academic and media debates over the nature of the MSWW and its programme. By pointing ou…
Do sex and pain characteristics influence the effectiveness of pain neuroscience education in people scheduled for total knee arthroplasty? Secondary…
2021
Abstract Objective This explorative study investigates the moderating effect of sex and baseline pain characteristics on the effectiveness of preoperative pain neuroscience education (PNE) plus knee joint mobilization versus biomedical education plus knee joint mobilization in patients who have knee osteoarthritis and are scheduled to undergo total knee arthroplasty (TKA). Methods After baseline assessment of self-reported questionnaires (pain intensity, disability, symptoms of central sensitization and pain cognitions) and quantitative sensory testing, 44 participants with knee osteoarthritis were randomized into the PNE plus knee joint mobilization or biomedical education plus knee joint …
Do organizational variables influence satisfaction with nursing student practices?
2021
Abstract Clinical practices are a vital component in the education of registered nursing students. This study analyzed the influence of organizational variables on satisfaction with clinical practices. A cross-sectional study design involved 572 registered nursing students. Two statistical methodologies, hierarchical regression models and qualitative comparative analysis of diffuse sets, were used for data analysis. In the hierarchical regression models the number of students supervised predicted satisfaction with clinical educator (β = -.22; p ≤ .001), environment (β = -.13; p ≤ .05) and overall satisfaction (β = -.15; p ≤ .05). However, in the qualitative comparative analysis, the type of…
Real-Life Clinical Data of Lenvatinib versus Sorafenib for Unresectable Hepatocellular Carcinoma in Italy
2021
Valentina Burgio,1 Massimo Iavarone,2 Giovanni Giuseppe Di Costanzo,3 Fabio Marra,4 Sara Lonardi,5,6 Emiliano Tamburini,7 Fabio Piscaglia,8 Gianluca Masi,9,10 Ciro Celsa,11 Francesco Giuseppe Foschi,12 Marianna Silletta,13 Daniela Caterina Amoruso,14 Margherita Rimini,15 Mariangela Bruccoleri,2 Raffaella Tortora,3 Claudia Campani,4 Caterina Soldà ,6 Massimo Giuseppe Viola,16 Antonella Forgione,8 Fabio Conti,12 Francesca Salani,9,10 Silvia Catanese,9,10 Carmelo Marco Giacchetto,17 Claudia Fulgenzi,13 Carmine Coppola,14 Pietro Lampertico,18 Antonio Pellino,6,19 Gabriele Rancatore,17 Giuseppe Cabibbo,17 Francesca Ratti,20 Federica Pedica,21 Angelo Della Corte,22 Massimo Colombo,18 Francesco De…
OCT-Angiography evaluation of peripapillary microvascular changes after rhegmatogenous retinal detachment repair
2021
Purpose: To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). Results: Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields…
Acceptance towards digital health interventions – Model validation and further development of the Unified Theory of Acceptance and Use of Technology
2021
Internet- and mobile-based interventions (IMI) offer an effective way to complement health care. Acceptance of IMI, a key facilitator of their implementation in routine care, is often low. Based on the Unified Theory of Acceptance and Use of Technology (UTAUT), this study validates and adapts the UTAUT to digital health care. Following a systematic literature search, 10 UTAUT-grounded original studies (N = 1588) assessing patients' and health professionals' acceptance of IMI for different somatic and mental health conditions were included. All included studies assessed Performance Expectancy, Effort Expectancy, Social Influence, Facilitating Conditions and acceptance as well as age, gender,…
Presentazione a: Luca Matranga e il suo tempo storico
2021
presentation to the volume : Luca Matranga e il suo tempo storico
Tracce dell’arcaico locativo nell’opera di Luca Matranga
2021
L’opera di Luca Matranga “E mbsuame e Krështerë” (1592), che dal punto di vista cronologico è, secondo monumento in albanese (dopo il “Messale” di Buzuku del 1555) e la prima testimonianza in dialetto tosco, fin dalla sua scoperta agli inizi del secolo scorso ha costituito una preziosa fonte di dati per i linguisti e gli studiosi della storia della lingua albanese. Pervenutaci in ben tre versioni manoscritte e una a stampa, la traduzione di Matranga ha vissuto una storia tanto travagliata quanto affascinante, soprattutto dal punto di vista della critica del testo e del trattamento strettamente filologico. L’opera ha conosciuto, infatti, ben quattro edizioni critiche parziali prima dell’ediz…
El Don Chisciotte in Sierra Morena de Apostolo Zeno y Pietro Pariati: del Quijote al libreto
2021
Zeno and Pariati are the authors of the libretto Don Chisciotte in Sierra Morena, composed by Francesco Conti and represented for the first time in 1719 at the court of Charles VI in Vienna. The episode has a central position in the First Part of Don Quixote, and offers several themes and a set of characters that hinder any reduction other literary genres. Apart from some changes due both to the requirements of opera poetry and the taste of the time, the analysis of the text of the libretto reveals a faithful relationship with the corresponding chapters of the Spanish work. However, when analysing the development of the reception of the themes and characters of Quixote, starting from the da…
Food products, gastronomy and religious tourism: The resilience of food landscapes
2021
Abstract Religious tourism has always been a sector of significant importance in the field of cultural tourism. Religious tourism is located both in urban areas and in rural areas. In rural areas in the past it did not represent a factor of great impact on the local economy as most of the population lived in rural areas. With the advent of modern society and with the phenomena of agricultural and rural exodus, linked to the increase in income in developed societies, religious tourism becomes a critical success factor for many rural areas as a historical heritage. This aspect is of significant importance if we consider that it can represent a real engine of development especially for rural a…
Chronic social defeat stress causes retinal vascular dysfunction
2021
Abstract Purpose The roles of vascular dysfunction and chronic stress have been extensively discussed in the pathophysiology of glaucoma. Our aim was to test whether chronic stress causes retinal vascular dysfunction and therewith induces retinal ganglion cells (RGCs) loss. Methods Twelve mice underwent chronic social defeat (CSD) stress, while 12 mice received control treatment only. Intraocular pressure (IOP) was measured with a rebound tonometer. Blood plasma corticosterone concentration and adrenal gland weight were used to assess stress levels. Brn-3a staining in retinas and PPD staining in optic nerve cross sections were conducted to assess the survival of RGCs and axons respectively.…
Skulls, Tree Bark, Fossils
2021
AbstractStudies of material objects in the field of memory studies have followed diverse epistemological and disciplinary trajectories, but their shared characteristic has been the questioning of philosophical assumptions concerning human relations with inanimate things and lower-level organic objects, such as plants, within the Aristotelian hierarchy of beings. Rather than accept at face value their categorizations as passive or deficient in comparison to the human subject, critical scholarship has reformulated the place and role of nonhuman entities in culture. This essay examines the nexus of materiality and memory in the work of the French philosopher and art historian Georges Didi-Hube…
Lexical Borrowing in the Light of Digital Resources: Nyet as a Case Study
2021
Abstract The mere appearance of a foreign word does not necessarily mark the birth of a loanword, which requires documented usage by the speech community. Relatively little research has been dedicated so far to the “prenatal” stage that would investigate the tentative infiltration of foreign-derived words. Nyet, a borrowing from Russian, is taken as a case in point. Although its first recorded instance in the Oxford English Dictionary (OED3) is dated to 1928, it had been increasingly recognized in English for several decades. This article focuses on textual attestations for nyet discovered in a range of digital resources, including British and American newspaper archives, and discusses thei…
DeepEva: A deep neural network architecture for assessing sentence complexity in Italian and English languages
2021
Abstract Automatic Text Complexity Evaluation (ATE) is a research field that aims at creating new methodologies to make autonomous the process of the text complexity evaluation, that is the study of the text-linguistic features (e.g., lexical, syntactical, morphological) to measure the grade of comprehensibility of a text. ATE can affect positively several different contexts such as Finance, Health, and Education. Moreover, it can support the research on Automatic Text Simplification (ATS), a research area that deals with the study of new methods for transforming a text by changing its lexicon and structure to meet specific reader needs. In this paper, we illustrate an ATE approach named De…
Integration of large-area optical imagers for biometric recognition and touch in displays
2021
In recent years there has been an increasing interest to integrate optical sensing in mobile displays, for instance, for biometric fingerprint scanning functionality. There are several routes to incorporate optical fingerprint functionality within the full display area, each with their own benefits and challenges. Here we investigate the different integration routes using large-area, ultra-thin imagers based on organic photodiodes.