showing 36 of ~574560 from 574555 documents
Surgical uprighting and repositioning of unerupted molars : features and findings of a retrospective sample
2021
Background Surgical uprighting and repositioning have been proposed to obtain a correct alignment of unerupted permanent molars. A retrospective clinical study was performed to verify the effectiveness of these techniques. Material and Methods In order for a case to be included in the study, adequate clinical documentation was required, including radiographic imaging before and after therapy. The degree of inclination of each treated molar was evaluated on pre-operative panoramic radiographs. Results Fifty-two molars were studied. Molar involvement was more frequent in the mandible (45 cases=86.54%) than in the maxilla (7 cases=13.66%). The mean age of patients treated with completely forme…
GM-CSF Programs Hematopoietic Stem and Progenitor Cells During Candida albicans Vaccination for Protection Against Reinfection
2021
More mechanistic studies are needed to reveal the hidden details of in vivo-induced trained immunity. Here, using a Candida albicans live vaccine mouse model we show that vaccination protects mice against a secondary infection and increases the number of bone marrow, and especially, splenic trained monocytes. Moreover, vaccination expands and reprograms hematopoietic stem and progenitor cells (HSPCs) early during infection and mobilize them transiently to the spleen to produce trained macrophages. Trained HSPCs are not only primed for myeloid cell production but also reprogramed to produce a greater amount of proinflammatory cytokines in response to a second challenge. Additionally, their a…
Attentional processing biases to threat in schizophrenia: Evidence from a free-viewing task with emotional scenes
2021
Attentional biases to threatening stimuli have been suggested to play a key role in the onset and course of schizophrenia. However, current research has not completely demonstrated this assumption. The aim of this eye-tracking study was to shed light on the underlying psychological mechanisms of schizophrenia by examining the attentional processing of socio-emotional information. Forty-four individuals with schizophrenia and 47 healthy controls were assessed in a 3-s free-viewing task with a social scene (i.e., happy, threatening, or neutral) in competition with a non-social one to determine the effects of emotional information on the different stages of the attentional processing. The loca…
Angiostrongiliasis humana. Aclaraciones a propósito del reporte de un caso importado en España
2021
Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology.
2021
Abstract Asymptomatic anthracosis is the accumulation of black carbon particles in adult human lungs. It is a common occurrence, but the pathophysiologic significance of anthracosis is debatable. Using in situ high mass resolution matrix-assisted laser desorption/ionization (MALDI) fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging analysis, we discovered noxious carbon-bound exogenous compounds, such as polycyclic aromatic hydrocarbons (PAH), tobacco-specific nitrosamines, or aromatic amines, in a series of 330 patients with lung cancer in highly variable and unique patterns. The characteristic nature of carbon-bound exogenous compounds had a strong association wi…
Una prospettiva storica e pedagogica sulle Lingue dei Segni: riflessioni psicolinguistiche
2021
Da oltre 50 anni, da quando W. Stokoe negli anni '60 individuò in USA i parametri di articolazione delle lingue dei Segni (cfr. Stokoe, 1981), si assiste ad un sempre maggiore interesse nei confronti delle lingue visivo-gestuali delle comunità di sordi, grazie anche agli sviluppi nel campo della psicolinguistica, delle neuroscienze, e delle nuove tecnologie che consentono indagini sul linguaggio e sul funzionamento cerebrale impensabili sino a qualche tempo fa. Può forse sorprendere che, in una prospettiva storica, all'interno del dibattito linguistico-filosofico si può riscontrare un analogo interesse per i sordi e le loro forme di comunicazione soltanto nella seconda metà del sec. XVIII e…
Nuovi spunti su Benedetto Bacchini e il paratesto editoriale
2021
Three centuries after the death of the Benedictine abbot Benedetto Bacchini (1645-1721), the publication of the proceedings of an important conference dedicated to him has made it possible to reconsider his figure as a religious and intellectual of European rank. Among the aspects worthy of renewed attention, the significant role of the paratextual apparatus emerged, as a privileged area for expressing in deep the historical thought and vision proposed by Bacchini. The editorial paratexts of some of Bacchini’s works that were entrusted to the printing houses without the intervention of the author, edited by scholars who had great esteem and / or had been very close to him, also offer releva…
Neurogranin as a Reliable Biomarker for Synaptic Dysfunction in Alzheimer’s Disease
2021
(1) Background: Neurogranin is a post-synaptic protein expressed in the neurons of the hippocampus and cerebral cortex. It has been recently proposed as a promising biomarker of synaptic dysfunction, especially in Alzheimer’s disease (AD). However, more efforts are needed before introducing it in clinical practice, including the definition of its reference interval (RI). The aim of the study was to establish the RI of cerebrospinal fluid (CSF) neurogranin levels in controls and individuals with non-neurodegenerative neurological diseases; (2) We included a total of 136 individuals that were sub-grouped as follows: AD patients (n = 33), patients with non-neurodegenerative neurological …
Post-traumatic Stress Disorder and Risk Factors in Patients With Acute Myocardial Infarction After Emergency Percutaneous Coronary Intervention: A Lo…
2021
This study aimed to investigate the status and risk factors of post-traumatic stress disorder (PTSD) in patients with acute myocardial infarction (AMI) after emergency percutaneous coronary intervention (PCI) in acute and convalescence phases. A longitudinal study design was used. Two questionnaire surveys were conducted in the acute stage of hospitalization, and 3 months after onset in patients. Logistic regression was used to analyze the risk factors for PTSD in AMI patients. The incidence of PTSD was 33.1 and 20.4% in acute and convalescent patients, respectively. The risk factors related to PTSD were door-to-balloon time (DTB) (≥92.6 min), left ventricular ejection fraction (LVEF) (&…
What determines a positive attitude towards natural food products? An expectancy theory approach.
2021
Natural food products are becoming increasingly popular worldwide due to their health and environmental benefits. However, these products' increasing anecdotal popularity has not translated into their widespread adoption; in fact, demand for natural food products remains confined to a relatively small segment of consumers. Despite this, little is known about the facilitators and inhibitors of favourable attitude of consumers towards these products. Recognising this gap, our study employed the theoretical lens of expectancy theory to investigate these factors. Through an extensive review of the pro-environmental consumption literature, we identified four facilitating and inhibiting factors: …
Above The Clouds: LabCity_Architecture
2021
The Winter Workshop “Cinema Paradise CAMPUS_Asia: SUAE_Asia 2021” brought to the attention of 14 teams and 5 Universities the challenge of contemporary architectural design in relation to a site of great naturalistic importance. In fact, the Bolognetta Valley, and in particular the location of the cave and the San Nicola waterfall, are located in the Sicilian hinterland, not far from the city of Palermo, in a context-free from the human presence. Here it is strong the necessity to find a design approach that can constitute a mediation between the built and the natural elements. The presence of the Milicia river then is also central to the whole understanding of the site, due to the restrict…
Subsurface swimming and stationary diving are metabolically cheap in adult Pacific walruses (Odobenus rosmarus divergens).
2021
ABSTRACT Walruses rely on sea-ice to efficiently forage and rest between diving bouts while maintaining proximity to prime foraging habitat. Recent declines in summer sea ice have resulted in walruses hauling out on land where they have to travel farther to access productive benthic habitat while potentially increasing energetic costs. Despite the need to better understand the impact of sea ice loss on energy expenditure, knowledge about metabolic demands of specific behaviours in walruses is scarce. In the present study, 3 adult female Pacific walruses (Odobenus rosmarus divergens) housed in professional care participated in flow-through respirometry trials to measure metabolic rates while…
Snapshot of a social movement: Mental health and protest classes in Hong Kong
2021
Abstract Background Popular protests have broken out worldwide, particularly in the last few years. In 2019, numerous demonstrations against an extradition bill occurred in Hong Kong until pandemic restrictions were imposed. The policing response relied heavily on methods such as batons, tear gas and rubber bullets. Given the relevance for other geographical contexts, the current study investigated the mental health impacts on protest participants and spillover to community members. Methods Surveys were disseminated on social media in August and October 2019 to collect demographics, political views, protest participation, exposure to (protest-related) potentially traumatic events (PTEs) and…
Maus: la geografia sociale nel mondo dei fumetti
2021
This contribution discusses Art Spiegelman's most famous graphic novel, Maus, in the light of social geography studies.
Scene giudiziarie nelle tragedie e nelle commedie latine del XII e XIII secolo. Il «De Affra et Flavio», il «De Paulino et Polla» di Riccardo da Veno…
2021
La commedia elegiaca e la tragedia latina del XII e XIII secolo mostrano una larga e varia ricchezza di caratteristiche, temi, soggetti e tipologie letterarie: uso del distico elegiaco, "imitatio" ovidiana, preponderanza della tematica amorosa, compresenza di narrazione e dialogo, e così via. Un elemento caratterizzante di alcune di queste commedie e tragedie medievali è rappresentato dalle scene giudiziarie. In questo saggio, dopo una breve introduzione sul genere letterario, viene svolta una puntuale analisi delle scene di giudizio che ricorrono in tre testi latini del XII e XIII secolo, una tragedia (l’anonimo «De Affra et Flavio»), una commedia elegiaca (il «De Paulino et Polla» di Ricc…
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
2021
Centrioles comprise the heart of centrosomes, microtubule-organizing centers. To study the function of centrioles in lung and gut development, we genetically disrupted centrioles throughout the mouse endoderm. Surprisingly, removing centrioles from the endoderm did not disrupt intestinal growth or development but blocked lung branching. In the lung, acentriolar SOX2-expressing airway epithelial cells apoptosed. Loss of centrioles activated p53, and removing p53 restored survival of SOX2-expressing cells, lung branching, and mouse viability. To investigate how endodermal p53 activation specifically killed acentriolar SOX2-expressing cells, we assessed ERK, a prosurvival cue. ERK was active t…
NUOVE FRONTIERE MUSEOGRAFICHE : immaterialità e multimedialità del museo narrativo
2021
Il contributo esplora, anche attraverso la lettura di alcuni casi studio, gli aspetti costitutivi e connotativi di ciò che può essere definita la nuova ‘frontiera della museografia’. Una ‘frontiera’ riconoscibile nella definizione di museo strutturato secondo il concetto ‘dell’allestimento integrato’ che si basa, prevalentemente, sul connubio tra strumentazioni tecnologiche avanzate, arte e interattività dei sistemi divulgativi dei contenuti museografici. In questi ultimi anni sono state sviluppate diverse esperienze museali caratterizzate da indagini sui nuovi linguaggi tecnologici, ma che non tralasciano la fondamentale elaborazione di scopi e contenuti degli stessi progetti allestitivi c…
Movimento femminile e democrazia in Sicilia: la Consulta regionale femminile del 1977
2021
This chapter aims to reconstruct the history of the political mobilization of Italian women. It focuses on the movement that from the early Seventies involved women active in Sicilian women's associations, political parties, and trade unions and, with them, militants who did not belong to any organization. In particular, the essay analyses the role played by the Italian Communist Party in introducing Italian women to the political arena of democratic Italy. In Sicily, one of the results of this mass mobilization and political participation was the political institutionalization into the Sicilian Regional Women's Council, established on 7 May 1977 with regional law number 272. In this contex…
Galloway-Mowat syndrome: New insights from bioinformatics and expression during Xenopus embryogenesis.
2021
Abstract Galloway-Mowat syndrome (GAMOS) is a rare developmental disease. Patients suffer from congenital brain anomalies combined with renal abnormalities often resulting in an early-onset steroid-resistant nephrotic syndrome. The etiology of GAMOS has a heterogeneous genetic contribution. Mutations in more than 10 different genes have been reported in GAMOS patients. Among these are mutations in four genes encoding members of the human KEOPS ( k inase, e ndopeptidase and o ther p roteins of small s ize) complex, including OSGEP, TP53RK, TPRKB and LAGE3. Until now, these components have been functionally mainly investigated in bacteria, eukarya and archaea and in humans in the context of t…
Posizionamenti transfemministi. Saperi situati e pratiche spaziali nel movimento Non Una di Meno
2021
The aim of this paper is to analyse, through the toolbox of gender geography, the methodology of positionality and situated knowledge. The article examines some spatial practices of the transfeminist movement Non Una di Meno that involve us both as researchers and activists. The different forms of territorialisation and ways of “doing with” the space of the movement, are here presented through the specific cases of the demonstrations organised during the Covid-19 pandemic on the 25th of November 2020 and 8th March 2021. This enables us to present the methodology of positionality, and to analyse how feminist spatial practices can be the object of research and vice versa.
Allusioni plautine ne «Gli ultimi giorni di Pompei» di Edward Bulwer-Lytton
2021
This note presents the summary and the analysis of citations, allusions and references to Plautus’s comedies in «The Last Days of Pompeii» by Edward Bulwer-Lytton. From the analysis here conducted it emerges that the English writer used Plautus for precise purposes, for ironic and satirical resolutions, appropriately contextualizing the allusions to Plautus within the plot of the novel.
Quantum gravity with THESEUS
2021
AbstractIn this paper we explore the possibility to search for a dispersion law for light propagation in vacuo with a sample of Gamma-Ray Bursts detected by the THESEUS satellite. Within Quantum Gravity theories, different models for space-time quantization predict relative discrepancies of the speed of photons w.r.t. the speed of light that (in a series expansion) depend on a given power of the ratio of the photon energy to the Planck energy. This ratio is as small as 10− 23 for photons in the soft γ −ray band (100 keV). The dominant effect is determined by the first significant term of this expansion. If the first order in this expansion is relevant, these theories imply a Lorentz Invaria…
Livedo: une présentation clinique rare de mycosis fongoïde avec vascularite
2021
Introduction Le mycosis fongoide (MF), lymphome cutane T primitif le plus frequent, peut prendre des formes cliniques tres variees. Nous rapportons 3 cas d’une forme rare associant des plaques de MF a des lesions livedoides necrotiques correspondant a une vasculite cutanee (VC) associee. Materiel et methodes Cas 1: Un patient de 82 ans aux antecedents de leucemie lymphoide chronique B et de MF traite par dermocorticoides presentait un livedo racemosa du tronc, complique de necroses et ulcerations cutanees douloureuses. L’aspect histologique etait celui d’un infiltrat lymphoide dermique atypique, de phenotype T CD3(+), CD4(+), CD8(-) avec pilotropisme et epidermotropisme, associe en profonde…
Il docente universitario: personalizzazione ed autoefficacia percepita
2021
Per rispettare le misure di distanziamento imposte dal COVID-19, le Università hanno dovuto adottare la didattica a distanza (DaD). L’occasione è stata propizia per cercare di personalizzare il processo di insegnamento-apprendimento, vale a dire per centrare meglio la formazione erogata dalle Università sulle esigenze dei singoli studenti. L’attuazione dei principi della didattica personalizzata ha richiesto un impegno non indifferente ai docenti che vi si sono cimentati. È stato ipotizzato che la percezione della propria capacità di personalizzare la formazione degli studenti con il supporto delle tecnologie dell’informazione e della comunicazione, influisse sull’efficacia didattica dei do…
Geografia sociale e partecipazione. L’esperienza di #esserefiera
2021
Social geography cannot be confined to a theoretical dimension, however necessary: it is expected to play an active role, to encourage encounters with social actors and stakeholders, to take on a dimension of public engagement. Even in Italy this dimension is increasingly important, as universities are placing a growing value on their so-called third mission. Social geography must then address the fundamental issue of participation and its techniques. In doing so, those who graduate in geography will also be able to claim an essential role in the management of decision-making processes and participatory planning. This paper explores some methods and approaches that younger geographers can u…
Cittadinizzazione e policy migratorie nella Sicilia occidentale : Progettare servizi innovativi rafforzando le Pubbliche Amministrazioni in attuazion…
2021
L’accesso ai servizi della pubblica amministrazione è spesso, per la popolazione migrante, un cercare la chiave giusta fra un numero spropositato di chiavistelli. Evidenziare come l’inserimento di alcuni servizi innovativi, fra i quali gli sportelli Mi.Main (Migration Mainstreaming) progettati e implementati da giovani laureati all’interno degli uffici della P.A., abbia di fatto favorito processi di “cittadinizzazione”, è stato lo scopo di questo volume. Preliminari ad ogni processo di inclusione sono infatti gli “atti di cittadinanza” che attraversano e ancorano l’universalità dei diritti umani al riconoscimento dei bisogni e delle priorità della persona. Questo volume, descrive come due t…
Determination of 60 Migrant Substances in Plastic Food Contact Materials by Vortex-Assisted Liquid-Liquid Extraction and GC-Q-Orbitrap HRMS
2021
A GC-HRMS analytical method for the determination of 60 migrant substances, including aldehydes, ketones, phthalates and other plasticizers, phenol derivatives, acrylates, and methacrylates, in plastic food contact materials (FCM) has been developed and validated. The proposed method includes migration tests, according to Commission Regulation (EU) 10/2011, using four food simulants (A, B, C, and D1), followed by vortex-assisted liquid–liquid extraction (VA-LLE) and GC-Q-Orbitrap HRMS analysis in selected ion monitoring (SIM) mode, with a resolving power of 30,000 FWHM and a mass accuracy ≤5 ppm. The method was validated, showing satisfactory linearity (R2 ≥ 0.98 from 40 to 400 …
Trophic ecology of a Late Pleistocene early modern human from tropical Southeast Asia inferred from zinc isotopes
2021
Tam Pà Ling, a cave site in northeastern Laos, has yielded the earliest skeletal evidence of Homo sapiens in mainland Southeast Asia. The reliance of Pleistocene humans in rainforest settings on plant or animal resources is still largely unstudied, mainly due to poor collagen preservation in fossils from tropical environments precluding stable nitrogen isotope analysis, the classical trophic level proxy. However, isotopic ratios of zinc (Zn) in bioapatite constitute a promising proxy to infer trophic and dietary information from fossil vertebrates, even under adverse tropical taphonomic conditions. Here, we analyzed the zinc isotope composition (66Zn/64Zn expressed as δ66Zn value) in the en…
VPP: A Communication Schema for Population Protocols in VANET
2021
Population protocols are a new paradigm that aims to model distributed systems composed of randomly interacting mobile agents. The main advantage of this model is that, when certain theoretical assumptions hold, it is possible to formally demonstrate their convergence. We consider the problem of adopting Population Protocols in a real-world scenario that does not guarantee these assumptions. In particular, we consider the application domain of Vehicular Ad-Hoc Networks (VANETs) which are characterized by dynamic network topologies, and where wireless communications can be affected by interferences and errors. In this work, we analyze the main features of VANET agents and the communications …
Male Sex Working and Masculinity: Finding ‘Check and Balance’ Between Stigmatisation and Homosexualisation
2021
Abstract in conference proceedings
Filtration of Nordic recirculating aquaculture system wastewater: Effects on microalgal growth, nutrient removal, and nutritional value
2021
Abstract Microalgal bioremediation of recirculating aquaculture system (RAS) wastewater represents an alternative for wastewater treatment with the potential to generate valuable biomass. This study evaluated the effects of removing biological contamination and suspended solids from Nordic area RAS wastewater through filtration with 0.45 μm filters on the performance and nutritional value of microalgae. All three tested green microalgae (Haematococcus pluvialis, Monoraphidium griffithii, and Selenastrum sp.) were able to grow in raw (unfiltered) and filtered RAS wastewater. Cultivation in raw RAS wastewater decreased the ω-3 and ω-6 fatty acid content of H. pluvialis as compared to filtered…
AGGIORNAMENTO SULLA DISTRIBUZIONE DEL SUCCIACAPRE Caprimulgidae) IN SICILIA CAPRIMULGUS EUROPAEUS (Aves
2021
Caprimulgus europaeus In recent years Update on the distribution of breeding Nightjar in Sicily. there have been numerous observations of Nightjar in areas where it had never previously been observed. In some cases the reason may be a deeper exploration, but in other cases the possible explanation is the expansion of the species. However, it is quite interesting the change in the habitat by this species. The present paper provides an update of its status based on data collected in the fifteen years following the publication of the last Sicilian Atlas of breeding birds.
Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
2021
To date, computational approaches have been recognized as a key component in drug design and discovery workflows. Developed to help researchers save time and reduce costs, several computational tools have been developed and implemented in the last twenty years. At present, they are routinely used to identify a therapeutic target, understand ligand–protein and protein–protein interactions, and identify orthosteric and allosteric binding sites, but their primary use remains the identification of hits through ligand-based and structure-based virtual screening and the optimization of lead compounds, followed by the estimation of the binding free energy. The repurposing of an old drug for the tr…
The psychological impact of COVID-19 on people suffering from dysfunctional eating behaviours: a linguistic analysis of the contents shared in an onl…
2021
The coronavirus disease 2019 (COVID-19) spread several months ago from China and it is now a global pandemic. The experience of lockdown has been an undesirable condition for people with mental health problems, including eating disorders. The present study has the aim of understanding the impact of the first wave of the COVID-19 pandemic on people with selfreported disordered eating behaviours. A linguistic analysis was carried out with regard to the online posts and comments published by 1971 individuals (86% women) in a Facebook online community focusing on EDs during the lockdown. A total of 244 posts and 3603 comments were collected during the 56 days of lockdown (from the 10th of March…
Integration of large-area optical imagers for biometric recognition and touch in displays
2021
In recent years there has been an increasing interest to integrate optical sensing in mobile displays, for instance, for biometric fingerprint scanning functionality. There are several routes to incorporate optical fingerprint functionality within the full display area, each with their own benefits and challenges. Here we investigate the different integration routes using large-area, ultra-thin imagers based on organic photodiodes.
Neoassunti e sviluppo delle competenze strategiche
2021
L’interesse della ricerca didattica anche in ambito internazionale converge sempre più sulla necessità di estendere la conoscenza dei fabbisogni formativi e professionali ad un’ampia gamma di competenze trasversali ritenute fondamentali per lo sviluppo personale e professionale del docente universitario. Quali competenze connotano il docente neoassunto oggi? Quali azioni e dispositivi di autovalutazione possono supportarne lo sviluppo professionale? Ci siamo proposti soprattutto l’obiettivo di comprendere la realtà della formazione dei neoassunti dando voce ai neoassunti e considerandoli una fonte di informazione strategica per leggere in maniera critica i processi attivati dalla somministr…