showing 36 of ~574560 from 574555 documents
The Fear of Covid-19 Scale (FCV-19S) in Spain: Adaptation and Confirmatory Evidence of Construct and Concurrent Validity
2021
Fear of the coronavirus has important implications on mental health. In western countries, a significant degree of vaccination has been achieved, but in Spain, less than 75% of the population has received both doses. The current situation is still seen as a threat by many people. Therefore, it is important to have reliable and valid measurement instruments to assess the impact of COVID-19 on the population. In this study, the Fear of COVID-19 Scale has been adapted to Spain, and its psychometric properties have been studied in a Spanish sample using Structural Equation Modeling. This methodology allows obtaining more reliable estimates, regardless of the measurement scale of the variables. …
Barriers and wellbeing-oriented enablers of intergenerational innovation in the digital age
2021
AbstractSo far, researchers have used a wellbeing-centered approach to catalyze successful intergenerational collaboration (IGC) in innovative activities. However, due to the subject’s multidisciplinary nature, there is still a dearth of comprehensive research devoted to constructing the IGC system. Thus, the purpose of this study is to fill a research void by providing a conceptual framework for information technology (IT) system designers to use as a jumping-off point for designing an IGC system with a wellbeing-oriented design. A systematic literature study was conducted to identify relevant terms and develop a conceptual framework based on a review of 75 selected scientific papers. The …
Exploring the Solar Wind from Its Source on the Corona into the Inner Heliosphere during the First Solar Orbiter-Parker Solar Probe Quadrature
2021
This Letter addresses the first Solar Orbiter (SO) -- Parker Solar Probe (PSP) quadrature, occurring on January 18, 2021, to investigate the evolution of solar wind from the extended corona to the inner heliosphere. Assuming ballistic propagation, the same plasma volume observed remotely in corona at altitudes between 3.5 and 6.3 solar radii above the solar limb with the Metis coronagraph on SO can be tracked to PSP, orbiting at 0.1 au, thus allowing the local properties of the solar wind to be linked to the coronal source region from where it originated. Thanks to the close approach of PSP to the Sun and the simultaneous Metis observation of the solar corona, the flow-aligned magnetic fiel…
The automated pancreas: A review of technologies and clinical practice
2021
Insulin pumps and glucose sensors are effective in improving diabetes therapy and reducing acute complications. The combination of both devices using an algorithm-driven interoperable controller makes automated insulin delivery (AID) systems possible. Many AID systems have been tested in clinical trials and have proven safety and effectiveness. However, currently, none of these systems are available for routine use in children younger than 6 years in Europe. For continued use, both users and prescribers must have sound knowledge of the features of the individual AID systems. Presently, all systems require various user interactions (e.g. meal announcements) because fully automated systems ar…
Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of…
2021
Abstract Brain-derived neurotrophic factor (BDNF) is an important modulator for a variety of functions in the central nervous system (CNS). A wealth of evidence, such as reduced mRNA and protein level in the brain, cerebrospinal fluid (CSF), and blood samples of Alzheimer’s disease (AD) patients implicates a crucial role of BDNF in the progression of this disease. Especially, processing and subcellular localization of BDNF and its receptors TrkB and p75 are critical determinants for survival and death in neuronal cells. Similarly, the amyloid precursor protein (APP), a key player in Alzheimer’s disease, and its cleavage fragments sAPPα and Aβ are known for their respective roles in neuropro…
Spin-crossover nanoparticles anchored on MoS2 layers for heterostructures with tunable strain driven by thermal or light-induced spin switching
2021
In the past few years, the effect of strain on the optical and electronic properties of MoS2 layers has attracted particular attention as it can improve the performance of optoelectronic and spintronic devices. Although several approaches have been explored, strain is typically externally applied on the two-dimensional material. In this work, we describe the preparation of a reversible ‘self-strainable’ system in which the strain is generated at the molecular level by one component of a MoS2-based composite material. Spin-crossover nanoparticles were covalently grafted onto functionalized layers of semiconducting MoS2 to form a hybrid heterostructure. Their ability to switch between two spi…
Evolution of SARS-CoV-2 immune responses in nursing home residents following full dose of the Comirnaty® COVID-19 vaccine
2021
ABSTRACTObjectivesThere is scarce information as to the durability of immune responses elicited by the Comirnaty® COVID-19 vaccine in nursing home residents. Here, we assessed SARS-CoV-2-Spike (S)-targeted antibody and functional T cell responses at around 6 months after complete vaccination.MethodsThe sample comprised 46 residents (34 females; age, 60-100 years), of whom 10 had COVID-19 prior to vaccination. Baseline (median of 17.5 days after vaccination) and follow-up (median, 195 days) plasma specimens were available for quantitation of SARS-CoV-2-S antibodies and enumeration of SARS-CoV-2-S-reactive IFN-γ CD4+ and CD8+ T cells by flow cytometry.ResultsIn total, 44/45 participants had d…
Mapping lava flows at Etna Volcano using Google Earth Engine, open-access satellite data, and machine learning
2021
Estimating eruptive parameters is fundamental to assess the volcanic hazards posed to the community living at the edge of active volcanoes. Here, we analyzed satellite remote sensing data by using machine learning unsupervised and supervised techniques and analytical approaches, i.e., mathematical-physics and statistics formulations, to map lava flows emitted during the long sequences of short-lived, violent eruptions occurred at Etna volcano between December 2020 and March 2021. Satellite observations allowed to follow the evolution of eruptions thanks to their capability to survey large areas with frequent revisit time and accurate spatial resolution. We quantified the areal coverage of l…
Associations of muscular fitness and body composition in children
2021
Purpose: To examine the associations between muscular fitness (MF) and body composition. Method: MF was assessed with three tests of FitnessGram test battery. Total body fat percentage (BF%), abdominal fat percentage (AF%) and fat-free mass (FFM) were measured by dual-energy X-ray absorptiometry (DXA). The IOTF body mass index (BMI) cut-offs were used to define healthy weight, overweight, and obesity. Results: MF was inversely associated with BF% and AF%. The children in the moderate and high MF groups had significantly lower BF% and AF% compared with the children in the low MF group within the same BMI category. After adjusting for cardiorespiratory fitness (CRF), BMI and sex, the differen…
La relació entre història de la llengua i història literària
2021
La relació entre la disciplina història de la llengua i la disciplina història de la literatura ha estat una relació de subordinació, tant des del punt vista conceptual com metodològic. La primera ha estat subordinada a la segona. En aquest article tractem en primer lloc de les circumstàncies i els esdeveniments històrics que han determinat aquesta situació de subordinació: la identificació cultural entre llengua i literatura (però amb la supeditació de la primera a la segona), el naixement de la lingüística romànica (que, paradoxalment, no va afavorir l’autonomia de la història de la llengua) i la desclosa de les cultures nacionals, que també van donar prioritat a la literatura nacional. E…
O galego-português, matriz do mundo lingüístico luso-brasileiro
2021
O período inicial desta breve história da língua galega e o reintegracionismo lingüístico começa com umhas observaçons de umha «Carta» de Martim Sarmiento (1695-1771), precursor da filologia galega, e finaliza em 2019, ano em que a Real Academia Galega (RAG), toma o acordo de dedicar-lhe o «Dia das Letras Galegas» ao polígrafo ferrolano Ricardo Carvalho Calero (Ferrol 1910 - Santiago de Compostela 1990). Elaboram-se apenas umhas ideias sobre o século XIX e primeira metade do XX; mais informaçom aparece sobre a segunda metade do século passado e primeiras décadas do XXI.
In-service teachers’ language attitudes in the Valencian educational system: the effect of the school language programme and the L1
2021
La investigació sobre les actituds dels professors cap a les llengües ha rebut una certa atenció, en la mesura que el multilingüisme s’ha convertit en un dels principals objectius educatius dels sistemes escolars europeus (Cenoz 2019; Liyanage & Tao 2020). Diversos autors (Lasagabaster 2017; Safont 2007) han afirmat que les actituds cap a les llengües poden resultar un factor crucial en l’educació multilingüe. En el sistema educatiu valencià, els estudis existents han investigat tant les actituds lingüístiques dels estudiants (Nightingale 2012, 2016; Portolés 2015) com les actituds lingüístiques del futur professorat (Lasagabaster & Safont 2008; Portolés 2014; Safont 2007) respecte …
Anna M. Moreno, Francesco Ardolino & Jordi Malé (eds.), «Manuel de Pedrolo, una mirada oberta. Noves perspectives crítiques i didàctiques», Lleida, A…
2021
Ressenya sobre el llibre d'Anna M. Moreno, Francesco Ardolino & Jordi Malé (eds.), Manuel de Pedrolo, una mirada oberta. Noves perspectives crítiques i didàctiques, Lleida, Aula Màrius Torres / Pagès editors, 2019, («Trossos», 11), 429 p., ISBN: 978-84-1303-138-5.
La dialèctica corpus/estatus en la història de la llengua catalana. Cap a una explicació integral dels canvis lingüístics
2021
En aquest article advoquem per la superació de les dicotomies que parcel·len l’estudi dels fets de llengua (sincronia vs. diacronia, lingüística vs. sociolingüística, història interna vs. història externa), en pro d’un atansament que integri el màxim nombre de factors explicatius possibles. Un àmbit propici per a aquesta confluència és l’anàlisi dels canvis lingüístics en curs, que són aquells que tenen lloc en temps real davant dels ulls de l’investigador, el qual es pot beneficiar així de la proximitat a l’objecte d’estudi i de l’accessibilitat als múltiples factors que en condicionen l’evolució, sempre que sigui capaç de no implicar-s’hi en excés. L’anàlisi de les transformacions que s’o…
Supportive and Palliative care
2021
The definition of palliative and supportive care is often overwhelming and may be confused in common clinical practice. Supportive care is the multiprofessional attention to the individual’s overall physical, psychosocial, spiritual, and cultural needs and should be available at all stages of the illness. Palliative care shares the same objectives of supportive care, and some authors consider it in the advanced stages of disease. Actually it is important to carry out all these interventions from the earlier phases of disease to improve patient quality of life, to prevent therapy discontinuation for side effects, and hence to an optimization of outcomes. Quality of life is a heterogeneous co…
Taste and oral microbiota
2021
International audience
Synthesis and pharmacological evaluation of enantiomerically pure endo-configured KOR agonists with 2-azabicyclo[3.2.1]octane scaffold
2021
Conformationally restricted bicyclic KOR agonists 10 with an endo configured amino moiety were synthesized to analyze the bioactive conformation of conformationally flexible KOR agonists such as 2-5. A seven-step, chiral pool synthesis starting with (S)-configured 4-oxopiperidine-2-carboxylate 13 was developed. cis and trans configured diesters 12 were obtained in a 3:1 ratio via hydrogenation of the α,β unsaturated ester 14. After establishment of the bicyclic scaffold, a diastereoselective reductive amination of ketone 11 provided exclusively the endo configured bicyclic amines 10a,b. The 3:1 mixtures of enantiomers were separated by chiral HPLC, respectively, leading to enantiomerically …
Complementarity between human capital and public infrastructure in industrial comparative advantage
2021
The article examines the role of public capital as an infrastructure service in the acquisition of industrial comparative advantages. To achieve this in this framework, we develop a theoretical model highlighting the complementarity between public and human capital as a mechanism of industrial development, and test this idea using sectoral panel data from 1999 to 2014 across 35 advanced and less advanced countries. Our results show that the sustainable acquisition of a comparative advantage in the production of industrial goods can only be guaranteed by accumulating public capital and human capital. It shows that public infrastructure can only generate industrialization when it is made avai…
Mar Massanell i Messalles, «“No m’à romasa sinó la honestat”. Rere la petja d’una innovació lingüística en el pas del català antic al modern», Barcel…
2021
Ressenya sobre el llibre de Mar Massanell i Messalles, «No m’à romasa sinó la honestat». Rere la petja d’una innovació lingüística en el pas del català antic al modern, Barcelona, Publicacions de l’Abadia de Montserrat, 2020, 450 p., ISBN: 978-84-9191-117-3.
La ideologia en el discurs de la història de la llengua: el tractament del procés sobiranista
2021
Aquest article analitza des de la teoria dels actes de parla els discursos socialitzats, entre 2016 i 2019, per la premsa polaritzada amb ideologies en conflicte en el context de l’anomenat procés sobiranista a Catalunya i l’Estat espanyol. Per una banda, es destaquen, amb un enfocament pragmàtic, alguns dels termes que el llenguatge mediàtic ha creat dins l’esfera sobiranista per construir-ne el relat ideològic; per l’altra, s’estudia la deslegitimació que n’han fet els mitjans d’àmbit estatalista en la construcció del contrarelat.
 En aquesta confrontació dialèctica argumentativa, els mitjans de comunicació, autèntics intermediaris sociocognitius entre el marc mental i el marc contex…
Krausisme juridique et politique en Europe
2021
The German philosopher of law Karl Krause (1781-1832), who is not well known in France, had a rich intellectual legacy. His philosophy is presented as a rationalist and humanist spiritualism. However, it is his political and legal aspects that will have the greatest impact. Indeed, in order to allow man to reach his "pure and complete humanity", the political side of Krausism carried a vast educational and progressive programme, inserted within a solidary liberalism and an organic democracy. The latter is built on a dualist representative system with a specific chamber for the representation of social interests, which some might see as a prefiguration of the corporate chambers. The aim is t…
Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner–Wadsworth–Emmons Olefination with PPARα/γ Agonist Activity
2021
[Image: see text] We have synthesized series of 2-prenylated benzopyrans as analogues of the natural polycerasoidol, a dual PPARα/γ agonist with anti-inflammatory effects. The prenylated side chain consists of five or nine carbons with an α-alkoxy-α,β-unsaturated ester moiety. Prenylation was introduced via the Grignard reaction, followed by Johnson–Claisen rearrangement, and the α-alkoxy-α,β-unsaturated ester moiety was introduced by the Horner–Wadsworth–Emmons reaction. Synthetic derivatives showed high efficacy to activate both hPPARα and hPPARγ as dual PPARα/γ agonists. These prenylated benzopyrans emerge as lead compounds potentially useful for preventing cardiometabolic diseases.
Opiskelijan ja opettajan opas monipuoliseen yliopisto-opiskeluun
2021
Oppaan tarkoituksena on tukea monikielisen ja multimodaalisen (monikanavaisen/monimediaisen) opiskelun kehittämistä Jyväskylän yliopistossa. Se on laadittu JY:n kasvatustieteiden ja psykologian tiedekunnassa osana Kieli- ja kulttuuritietoisen oppimisen tilat -hanketta lukuvuoden 2019–2020 aikana, ja siinä on hyödynnetty ja kehitetty edelleen JY:n muita opinto-oppaita . Opas on yleishyödyllinen, koska se lisää kieli- ja kulttuurinäkökulmia aiemmin laadittuihin opinto-oppaisiin. Mukana on kuvauksia erityyppisistä tehtävistä ja aktiviteeteista, jotka kuuluvat korkeakouluopiskeluun ja -opetukseen. Lisäksi opas sisältää hyödyllisiä vinkkejä opiskelijoille ja opettajille, ehdotuksia eri kielten k…
Presentació del monogràfic «Com s'escriu avui la història de la llengua catalana?»
2021
Presentació del monogràfic «Com s’escriu avui la història de la llengua catalana?», coordinat per Miquel Nicolás.
An organogold compound as potential antimicrobial agent against drug resistant bacteria: Initial mechanistic insights
2021
Abstract The rise of antimicrobial resistance has necessitated novel strategies to efficiently combat pathogenic bacteria. Metal‐based compounds have been proven as a possible alternative to classical organic drugs. Here, we have assessed the antibacterial activity of seven gold complexes of different families. One compound, a cyclometalated Au(III) C^N complex, showed activity against Gram‐positive bacteria, including multi‐drug resistant clinical strains. The mechanism of action of this compound was studied in Bacillus subtilis. Overall, the studies point towards a complex mode of antibacterial action, which does not include induction of oxidative stress or cell membrane damage. A number …
«A vós qui sou la bella i alta rima» (Els participants en la ‘Resposta’ trobada de Miquel Ortigues)
2021
En el marc de la realització de la tesi doctoral sobre el notari valencià Miquel Ortigues, hem estudiat l’obra atribuïda així com qüestions d’aspectes biogràfics i contextuals. En aquest article ens centrem en la importància de l’aparició d’una composició inèdita trobada en els seus protocols notarials i una revisió sobre la magnitud del personatge a partir de les relacions literàries que s’expliciten en els versos. L’article representa un nou enfocament sobre Miquel Ortigues que té en compte dades empíriques recollides als arxius. De forma col·lateral també significa la irrupció d’altres dos poetes, Ausiàs Crespí de Valldaura i Joan Ram Escrivà en el panorama poètic de les preguntes i resp…
Effect of the COVID-19 pandemic on foot surgeries.
2021
Background Musculoskeletal dysfunction due to deformities and injuries of the foot is a common orthopedic problem. Objectives To analyze the effect of the COVID-19 pandemic on both elective and emergency foot surgeries. Material and methods This study analyzed the effect of the COVID-19 pandemic on elective and emergency foot surgeries. The comparison included data collected in 2019 (March 15-October 15, when the epidemic did not influence the Polish healthcare system or patient demographics) and in a corresponding period in 2020. This study was conducted in the trauma and orthopedic surgery wards and the emergency departments of 2 regional Polish hospitals. Results The analysis of the data…
Jean-François Sablayrolles, «Comprendre la néologie. Conceptions, analyses, emplois», Llemotges, Éditions Lambert-Lucas (col·lecció «La Lexicothèque»…
2021
Ressenya sobre el llibre de Jean-François Sablayrolles, Comprendre la néologie. Conceptions, analyses, emplois, Llemotges, Éditions Lambert-Lucas (col·lecció «La Lexicothèque»), 2019, 312 p., ISBN: 978-2-35935-286-3.
Consumers' eating habits during the Covid-19 pandemic: Evidence of an experimental analysis in Italy.
2021
During the COVID-19 pandemic, the Italian food supply chain responded to the needs of consumers by giving continuity to the supply of food products even if the Italian food system in the first phase of lockdown had to deal with the anxiety of consumers who rushed to the food stores to "clear the shelves ". The aim of this research is to provide a qualitative interpretation of Italian families' food consumption experiences during the lockdown due to Covid-19, which lasted from March 9, 2020 to May 4, 2020. This research has examined twenty Italian families and reveals that anxiety about the exhaustion of food stocks was detected in the first weeks of the lockdown, where there were consumers …
Problemes de la periodització en història de la llengua
2021
El treball analitza l’adequació de les perioditzacions de la història de la llengua catalana amb l’objectiu proposar-ne una que siga compatible amb el caràcter social de què actualment pretenen revestir-se la majoria de les històries de la llengua. Així, es considera fora de lloc el tractament d’algun període previ a l’existència de la llengua catalana, com la de la romanització, i es rebutja alguna etiqueta que és una tradició inventada, com la de la reconquista. La proposta d’una periodització es resumeix en quatre etapes basades en factors sociolingüístics: sorgiment, consciència, plenitud i conflicte lingüístic. The work analyses how of suitable are the periodizations of the history of …
Editorial: Exploring Plant Rhizosphere, Phyllosphere and Endosphere Microbial Communities to Improve the Management of Polluted Sites
2021
International audience
Improvising on Emotion Terms: Students’ Strategies, Emotional Communication, and Aesthetic Value
2021
Studies in musical improvisation show that musicians and even children are able to communicate intended emotions to listeners at will. To understand emotional expressivity in music as an art form, communicative success needs to be related to improvisers’ thought processes and listeners’ aesthetic judgments. In the present study, we used retrospective verbal protocols to address college music students’ strategies in improvisations based on emotion terms. We also subjected their improvisations to expert ratings in terms of heard emotional content and aesthetic value. A qualitative analysis showed that improvisers used both generative strategies (expressible in intramusical terms) and imagina…
Organizational information and communication technologies and their influence on communication visibility and perceived proximity
2021
This study investigates the relationships between the use of various organizational ICTs, communication visibility, and perceived proximity to distant colleagues. In addition, this study examines the interplay between visibility and proximity, to determine whether visibility improves proximity, or vice versa. These relationships are tested in a global company using two waves of panel survey data. ESM use increases communication visibility and perceived proximity, while controlling for prior levels of visibility, proximity, and the use of other organizational ICTs. The influence of ESM on network translucence and perceived proximity is generally stronger than the impact of other technologie…
L'epístola en la poesia de Vicent Andrés Estellés
2021
Aquest treball revisa les composicions poètiques que Vicent Andrés Estellés va considerar i anomenar epístoles al llarg de la seua extensa producció literària. Aquest tipus de composicions, juntament amb les èglogues, van ser importants en la seua confirmació com a poeta en llengua catalana en els anys cinquanta, i, a més, aquestes van aportar un to conversacional a la seua poesia, on el jo poètic aprofitava el tu interlocutor i destinatari per tal de construir-se en el text. L’estudi publica, entre els textos revisats, tres poemes epistolars inèdits.
Different Pitch Configurations Constrain the Playing Tactics and the Creation of Goal Scoring Opportunities during Small Sided Games in Youth Soccer …
2021
The aim of this study was to explore the tactical effects of different pitch configurations on the collective playing tactics and the creation of goal scoring opportunities (GSO) during small sided soccer games (SSG) in youth players. A total of 22 players performed a 7 vs. 7 + 1 floater (including goalkeepers) under three different pitch configurations (“Standard”, 53 × 38 m
Joseph García Rodríguez, «La fraseología del español y el catalán. Semántica cognitiva, simbolismo y contrastividad», Berlín, Peter Lang, 2020, 308 p.
2021
Book review: Joseph Garcia Rodriguez, La fraseologia del espanol y el catalan. Semantica cognitiva, simbolismo y contrastividad , Berlin, Peter Lang, 2020, 308 p., ISBN: 978-3-631-82445-0.