showing 36 of ~574560 from 574555 documents
Environmental risk factors and cardiovascular diseases: a comprehensive expert review.
2021
Abstract Non-communicable diseases (NCDs) are fatal for more than 38 million people each year and are thus the main contributors to the global burden of disease accounting for 70% of mortality. The majority of these deaths are caused by cardiovascular disease (CVD). The risk of NCDs is strongly associated with exposure to environmental stressors such as pollutants in the air, noise exposure, artificial light at night, and climate change, including heat extremes, desert storms, and wildfires. In addition to the traditional risk factors for CVD such as diabetes, arterial hypertension, smoking, hypercholesterolaemia, and genetic predisposition, there is a growing body of evidence showing that …
Evaluation of a High School Practical Experience on Noise Pollution With Smartphones
2021
This work presents the evaluation of a practical experience on noise pollution based on the use of smartphones to check if it helps students to better understand the concepts related to this phenomenon. This evaluation has been done with a pre-post design in which 112 students, enrolled in the “Physics and Chemistry” course of the 1st year of non-compulsory high school, have first filled in a diagnostics questionnaire with 5 free response questions about their knowledge on the topic and then a pre-post questionnaire with 4 free response questions. The results show that the proposed practical experience is effective since a statistically significant improvement is obtained both globally and …
A systematic literature review of participatory design studies involving teachers
2021
Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone
2021
Osteoporotic vertebral fractures often necessitate fusion surgery, with high rates of implant failure. We present a novel bioactive composite of calcium phosphate cement (CPC) and the collagen I mimetic P-15 for pedicle screw augmentation in osteoporotic bone. Methods involved expression analysis of osteogenesis-related genes during osteoblastic differentiation by RT-PCR and immunostaining of osteopontin and Ca2+ deposits. Untreated and decalcified sheep vertebrae were utilized for linear pullout testing of pedicle screws. Bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry (DEXA). Expression of ALPI II (p <
Vivere come donne in India: l'insolito genere delle comunità hijra
2021
The study aims to investigate the history and practices that characterize hijra communities in India in order to shed light on the specific reality of these heterogeneous communities of individuals who are placed outside the heteronormative identity codes, but who have historically been included within Indian society, with very specific roles, thanks to the elaboration of the notion of tṛtīya prakṛti (third gender). However, historical events, especially since the British colonial period, have made the position of hijras increasingly marginal: the various forms of discrimination and violence, which take place within the family of origin, the health system, and society in general, were furth…
Linguistic Landscape geht digital: „Virtuelle sprachliche Landschaften“ auf Instagram am Beispiel der Weinstraßen in zwei mehrsprachigen Regionen (El…
2021
International audience; Kontext Die heutige Digitalisierung der Kommunikation wirft ein neues Licht auf traditionelle LL-Praktiken und -Problemstellungen (Androutsopoulos 2014). In Anschluss an Ivkovic & Lotherington (2009) und auf der Pilotstudie von Hiipala et al. (2019) aufbauend kann ein neuer Strang in der LL-Forschung identifiziert werden, der den gut etablierten LL-Begriff auf digitale und virtuelle Räume auszudehnen versucht, wie an der Prägung des Begriffs „virtuelle sprachliche Landschaft“ abgelesen werden kann. Parallel dazu werden soziale Netzwerke heutzutage immer mehr in touristischen Kontexten verwendet, an erster Stelle von Touristinnen, die somit – und meistens unmittelba…
Statistical-Dynamical Forecasting of Sub-Seasonal North Atlantic Tropical Cyclone Occurrence
2021
AbstractWhile previous research on sub-seasonal tropical cyclone (TC) occurrence has mostly focused on either the validation of numerical weather prediction (NWP) models, or the development of statistical models trained on past data, the present study combines both approaches to a statistical–dynamical model for probabilistic forecasts in the North Atlantic basin. Although state-of-the-art NWP models have been shown to lack predictive skill with respect to sub-seasonal weekly TC occurrence, they may predict the environmental conditions sufficiently well to generate predictors for a statistical model. Therefore, an extensive predictor set was generated, including predictor groups representin…
false
2021
Myoglobin (MB) is an oxygen-binding protein usually found in cardiac myocytes and skeletal muscle fibers. It may function as a temporary storage and transport protein for O2 but could also have scavenging capacity for reactive oxygen and nitrogen species. In addition, MB has recently been identified as a hallmark in luminal breast cancer and was shown to be robustly induced under hypoxia. Cellular responses to hypoxia are regulated by the transcription factor hypoxia-inducible factor (HIF). For exploring the function of MB in breast cancer, we employed the human cell line MDA-MB-468. Cells were grown in monolayer or as 3D multicellular spheroids, which mimic the in vivo avascular tumor arch…
Decreasing Phanerozoic extinction intensity as a consequence of Earth surface oxygenation and metazoan ecophysiology
2021
The decline in background extinction rates of marine animals through geologic time is an established but unexplained feature of the Phanerozoic fossil record. There is also growing consensus that the ocean and atmosphere did not become oxygenated to near-modern levels until the mid-Paleozoic, coinciding with the onset of generally lower extinction rates. Physiological theory provides us with a possible causal link between these two observations-predicting that the synergistic impacts of oxygen and temperature on aerobic respiration would have made marine animals more vulnerable to ocean warming events during periods of limited surface oxygenation. Here, we evaluate the hypothesis that chang…
« Les dispositifs numériques au cœur de la patrimonialisation »
2021
International audience
Conditioned generalisation in generalised anxiety disorder: the role of concurrent perceptual and conceptual cues
2021
Previous research in extinction indicates no difference in US expectancies for aversive and non-aversive unconditioned stimuli (USs). In this study, we bridged these topics by examining how concurrent perceptual and conceptual cues influence conditioned generalisation of generalised anxiety disorder (GAD) patients by using non-aversive USs. The study included two consecutive phases: acquisition and generalisation. In the acquisition phase, we used blue and purple images as the perceptually conditioned stimuli, images of animals and household items as the conceptually conditioned stimuli, and non-aversive images as unconditioned stimuli (US). In the generalisation phase, we used images conta…
Manufacturing export performance and public capital: an analysis by country technology position
2021
The objective of this paper is to examine the relationship between public capital and manufacturing export performance. It also aims at investigating whether this relationship depends on the proximity of a country's technology frontier. To achieve this, we adopted a methodology that estimates the elasticities of public capital as a non-rival factor in a model that considers factor intensity as a mechanism of industrial development. We use an interaction model with panel data from 1999 to 2014 across 35 advanced and less advanced countries. Our results show that in countries far from the technology frontier, public capital accumulation is an element of industrial development as opposed to co…
A Methodological Approach for Developing and Validating a Parsimonious and Robust Measurement Tool: The Academic E-Service Quality (ACEQUAL) Model
2021
Nowadays, in the higher education sector, the quality measurement process of education-related services is assuming a crucial role to support focused and targeted improvement activities deeply centered on students’ needs/necessities. These are considered crucial factors for dealing with the current academic competitive context. Therefore, the quality measurement process has to be precise and accurate, namely the measurement model on which it is based has to be parsimonious and robust. The present work proposes an effective and easy-to-use methodological approach suitable for supporting the structuring of a measurement tool. Its effectiveness is shown with reference to the academic e-service…
Enantioselective addition of sodium bisulfite to nitroalkenes. A convenient approach to chiral sulfonic acids
2021
An enantioselective organocatalytic addition of sodium bisulfite to (E)-nitroalkenes has been developed by using a chiral bifunctional organocatalyst. The present methodology provides a variety of chiral β-nitroethanesulfonic acid compounds (17 examples) with excellent results: up to 99% yield and excellent enantioselectivity (up to 96% ee). The reaction tolerates (hetero)aryl and alkyl substituents on the β-nitroalkenes, and β,β-disubstituted nitroalkenes.
Megabenthos Underwater Video (MUV): a new device to evaluate species distribution in hard-to-reach marine areas
2021
A device, called Megabenthos Underwater Video (MUV), was designed and built for the counting and the size estimate of benthic organisms in hard-to-reach areas. Since 2014 Cassiopea andromeda, an invasive alien jellyfish in the Mediterranean Sea with benthic behavior, colonized a recreational harbor (Cala) of Palermo with a stable population. Studying the species distribution in this area with classical methods (such as visual census, ROV, etc.) was not applicable due to the large presence of obstacles (ropes, anchor cables, boats) and to dive difficulties in these types of area. The MUV was tested from 2017 to 2018 for the study of the spatial-temporal distribution of C. andromeda in the Ca…
Self-censorship and Shifting Cognitions of Offence in the Stand-up Acts of Basket Mouth and Trevor Noah
2021
With social media taking stand-up routines beyond their hitherto localised environments, there is growing irritation and backlash against comedians who supposedly tell unpleasant (or offensive) jok...
Efficient spatial designs using Hausdorff distances and Bayesian optimization
2021
An iterative Bayesian optimisation technique is presented to find spatial designs of data that carry much information. We use the decision theoretic notion of value of information as the design criterion. Gaussian process surrogate models enable fast calculations of expected improvement for a large number of designs, while the full-scale value of information evaluations are only done for the most promising designs. The Hausdorff distance is used to model the similarity between designs in the surrogate Gaussian process covariance representation, and this allows the suggested algorithm to learn across different designs. We study properties of the Bayesian optimisation design algorithm in a sy…
In situ behavior of wild long-snouted seahorse Hippocampus guttulatus Cuvier, 1829
2021
The study of behavior is one of the fundamental aspects of conservation biology. While for animals such as mammals there are well-defined protocols that have been applied for a long time, for marine animals, and fish in particular, studies are available for a limited number of species. The behavior of seahorses, for example, is poorly studied and in this work, we made a first attempt of using video recordings to analyze behavior of these endangered species in Mar Piccolo of Taranto (Southern Italy). The study presents preliminary data on behavioral activities and their comparisons among different life stages of Hippocampus guttulatus, namely females, males, and juveniles. Juveniles and fema…
Influence of early life risk factors and lifestyle on systemic vascular resistance in later adulthood : the cardiovascular risk in young Finns study
2021
Purpose: There are limited data available concerning the effects of lifetime risk factors and lifestyle on systemic hemodynamics, especially on systemic vascular resistance. The purpose of the study was to evaluate how lifetime cardiovascular risk factors (body mass index (BMI), high-density lipoprotein, low-density lipoprotein, triglycerides, systolic blood pressure, blood glucose) and lifestyle factors (vegetable consumption, fruit consumption, smoking and physical activity) predict systemic vascular resistance index (SVRI) and cardiac index (CI) assessed in adulthood. Materials and Methods: Our study cohort comprised 1635 subjects of the Cardiovascular Risk in Young Finns Study followed …
The Ecology of Hyperparasitoids.
2021
Hyperparasitoids are some of the most diverse members of insect food webs. True hyperparasitoids parasitize the larvae of other parasitoids, reaching these larvae with their ovipositor through the herbivore that hosts the parasitoid larva. During pupation, primary parasitoids also may be attacked by pseudohyperparasitoids that lay their eggs on the parasitoid (pre)pupae. By attacking primary parasitoids, hyperparasitoids may affect herbivore population dynamics, and they have been identified as a major challenge in biological control. Over the past decades, research, especially on aphid- and caterpillar-associated hyperparasitoids, has revealed that hyperparasitoids challenge rules on nutri…
Can cystic lesions of the jaws be considered as the cause of mandibular asymmetry?
2021
The aim of this study is to investigate the presence of condylar and ramal asymmetry in patients with a cyst larger than 10 mm in the maxilla or mandible. Condylar and ramal asymmetry index measurements of 47 patients (mean age: 28.85 ± 15.348) in the study group and 40 patients in the control group (mean age: 33.73 ± 13.095) were performed using panoramic radiographs. The study group consists of patients with cysts larger than 10 mm in diameter in the maxilla or mandible. The control group consisted of patients with no radiolucent lesions and no history of trauma. The possible statistical difference between the groups was evaluated by the Mann-Whitney U test. No statistically significant d…
Dentulous versus edentulous mandibles: CBCT-based morphometric assessment of mandibular canal and alveolar bone
2021
Precise preoperative knowledge of the mandibular canal (MC) variations and alveolar bone dimensions are vital elements for a successful dental implant. Thus, this study aimed to describe the three-dimensional morphology of the MC and alveolar bone dimensions, followed by a comparison of the variables in edentulous mandibular posterior sides with contralateral dentulous sides among adult Chinese individuals. Such variations were also studied in relation to gender and age.Cone-beam computed tomography (CBCT) was used for the morphometric analysis of the MC and alveolar bone dimensions in this cross-sectional study that analyzed retrospectively gathered data. Records of 112 individuals (56 mal…
High efficiency and clinical relevance of exome sequencing in the daily practice of neurogenetics
2021
ObjectiveTo assess the efficiency and relevance of clinical exome sequencing (cES) as a first-tier or second-tier test for the diagnosis of progressive neurological disorders in the daily practice of Neurology and Genetic Departments.MethodsSixty-seven probands with various progressive neurological disorders (cerebellar ataxias, neuromuscular disorders, spastic paraplegias, movement disorders and individuals with complex phenotypes labelled ‘other’) were recruited over a 4-year period regardless of their age, gender, familial history and clinical framework. Individuals could have had prior genetic tests as long as it was not cES. cES was performed in a proband-only (60/67) or trio (7/67) st…
Religious Diaspora: A New Approach to Its Existence and Meaning
2021
The present study aims to contribute to the discussion regarding the possibility of conceptualizing a religious diaspora. It proposes a new way of defining it, namely in relation to religious and not to ethno-territorial realities, but without editing the territorial dimension out. After sketching the definition on this theoretical basis, the study refers to six case studies, pointing to the way in which the definitory traits of a religious diaspora are actualized in each situation under study. The evaluation unravels the strengths of the concept as well as certain aspects that still need to be addressed in further research. The inference is that the capacity of religion to generate diaspor…
Consumer Satisfaction towards Green Products: Empirical Insights from Romania
2021
The current model of linear economy is causing accelerated consumption and an extensive use of natural resources that accentuates the effects of the current global environmental crisis. In this context, green products are becoming a key element in the transition to a sustainable consumption and production model. The main goal of this paper is to identify the factors predicting youth consumer satisfaction towards green products and to analyze the public perception of green brand products in Romania. Considering these goals, a questionnaire was developed and applied to 268 participants. The results show that a positive attitude towards green products and the level of information held by the c…
nmr solution structure of lysostaphin
2021
A Life Cycle Environmental Impact Comparison between Traditional, Hybrid, and Electric Vehicles in the European Context
2021
Global warming (GW) and urban pollution focused a great interest on hybrid electric vehicles (HEVs) and battery electric vehicles (BEVs) as cleaner alternatives to traditional internal combustion engine vehicles (ICEVs). The environmental impact related to the use of both ICEV and HEV mainly depends on the fossil fuel used by the thermal engines, while, in the case of the BEV, depends on the energy sources employed to produce electricity. Moreover, the production phase of each vehicle may also have a relevant environmental impact, due to the manufacturing processes and the materials employed. Starting from these considerations, the authors carried out a fair comparison of the environmental …
Cancer in Children With Fanconi Anemia and Ataxia-Telangiectasia—A Nationwide Register-Based Cohort Study in Germany
2021
PURPOSE Fanconi anemia (FA) and ataxia-telangiectasia (AT) are rare inherited syndromes characterized by abnormal DNA damage response and caused by pathogenic variants in key DNA repair proteins that are also relevant in the pathogenesis of breast cancer and other cancer types. The risk of cancer in children with these diseases is poorly understood and has never been assessed in a population-based cohort before. METHODS We identified 421 patients with FA and 160 patients with AT diagnosed between 1973 and 2020 through German DNA repair disorder reference laboratories. We linked patients' laboratory data with childhood cancer data from the German Childhood Cancer Registry. RESULTS Among 421 …
Jewish Tetouan: place, community, and ethnic boundaries from the Minutes Book of the community board, 1929-46
2021
Differences in psychodynamic conflicts between healthy adolescents and adolescent patients: Results with the conflict questionnaire
2021
Improving referral of patients with diabetic foot ulcer to specialised diabetes foot care units.
2021
The Determinants of Living with Long-Term Conditions: An International Cross-Sectional Study
2021
It is essential that healthcare and social professionals understand the daily lives of people with chronic diseases, and the variables that influence them. The aim of this study was to identify the determinants influencing the process of living with long-term conditions. To investigate this, an observational, international, cross-sectional study was carried out. A consecutive sample of 1788 Spanish-speaking population living with chronic obstructive pulmonary disease, chronic heart failure and type 2 diabetes mellitus were included. Descriptive statistics and multiple linear regression models were performed. The linear regression models identified that social support (β = 0.39, p <
Influence of Female Sex Hormones on Ultra-Running Performance and Post-Race Recovery: Role of Testosterone
2021
In recent years, increasing numbers of women have participated in extremely long races. In adult males, there is a clear association between physiological levels of endogenous sex hormones and physical performance. However, the influence of plasmatic sex hormones and the effects of different types of hormonal contraception (HC) on the modulation of physical performance in adult females remain to be fully clarified. Eighteen female ultra-endurance athletes were recruited to participate in the study. Different variables were studied, including hematological parameters, body mass index, and body composition. Strength measurements were obtained using the squat-jump and hand-grip test. A repeate…
Introduction: Jewish cultural heritage, space and mobility in Spain, Portugal and North Africa
2021
Construction of a webgis tool based on a gis semiautomated processing for the localization of p2g plants in sicily (Italy)
2021
The recent diffusion of RES (Renewable Energy Sources), considering the electric energy produced by photovoltaic and wind plants, brought to light the problem of the unpredictable nature of wind and solar energy. P2G (Power to Gas) implementation seems to be the right solution, transforming curtailed energy in hydrogen. The choice of the settlement of P2G plants is linked to many factors like the distances between the gas grid and the settlement of RES plants, the transportation networks, the energy production, and population distribution. In light of this, the implementation of a Multi-Criteria Analysis (MCA) into a Geographic Information System (GIS) processing represents a good strategy …
Experiences of Female Breast Cancer Survivors Concerning Their Return to Work in Spain
2021
The objective of this study was to analyze the experiences of returning to work of women who had overcome breast cancer, identifying its physical and psychological consequences, the process they underwent, their motivations, and difficulties. A total of 19 female breast cancer survivors, with an age range of 30 to 57 years, participated in two focus groups. A semi-structured script was prepared about their experiences of returning to work. The results indicated that survivors’ self-perception was weakened by the physical and psychological consequences of the treatment of the disease