showing 36 of ~574560 from 574555 documents
Selective T3–T4 sympathicotomy versus gray ramicotomy on outcome and quality of life in hyperhidrosis patients: a randomized clinical trial
2021
Abstract Background: compensatory hyperhidrosis is the leading cause of patients' dissatisfaction after thoracic sympathicotomy.Objective: to reduce compensatory hyperhidrosis to increase patients' satisfaction. Patients and methods: a prospective randomized study on palmar hyperhidrosis, May 2016-September, 2019. Twenty-one patients T3-T4 sympathicotomy and 21 T3-T4 gray ramicotomy. Data prospectively collected. Analysis at study's end. Focus on the sweating, temperature, quality of life baseline and postoperatively, compensatory hyperhidrosis, hand dryness, patients' satisfaction, and if they would undergo the procedure again and would recommend it.Results: No baseline differences between…
Detection of Anaplasma phagocytophilum in Wild and Farmed Cervids in Poland
2021
Background: The role of cervids in the circulation of A. phagocytophilum has not yet been clearly determined
VOT production, writing skills, and general proficiency in multilingual learners of French: approaching the intertwinement of different linguistic le…
2021
Abstract We investigate the interrelations between pronunciation and writing skills in French as a foreign language produced by two groups of bilingual learners (German-Russian; German-Turkish) and a monolingually raised German control group (each n = 10). As an indicator of the learners’ pronunciation skills, we refer to a perceptually relevant acoustic feature of stop production, “Voice Onset Time” (VOT). Our aim is to explore whether the learners’ proficiency at the level of pronunciation is mirrored in (1) their global language competencies and (2) their writing skills. We applied an extreme-cases approach based on the learners’ VOT productions in L3 French. Both positive and negative d…
Hsp27 and Hsp60 in human submandibular salivary gland: Quantitative patterns in healthy and cancerous tissues with potential implications for differe…
2021
Tumors of the submandibular salivary gland (SMG) are uncommon but sufficiently frequent for the physician to consider them in routine examinations and for the pathologist to be prepared to differentiate them from other tissue abnormalities. However, scarcity of specimens makes training difficult, a situation compounded by the lack of accepted universal diagnostic guidelines. Furthermore, there is little information on the chaperone system (CS) of the gland, despite the increasing evidence of its participation in carcinogenesis as a biomarker for diagnosis and patient follow up, and in the mechanisms by which the tumor cells thrive. We are investigating this aspect of various tumors, and her…
Novel Digital Measurement Technique to Analyze the Palatine Suture Expansion after Palatine Rapid Maxillary Expansion Technique
2021
The aim of the study was to validate a novel digital measurement method to quantify the volume of the midpalatal suture after rapid maxillary expansion (RME). Material and methods: Eight patients with maxillary skeletal transverse deficiency were submitted to palatine suture expansion using the McNamara orthodontic appliance during a period of nine months. After 30 days of treatment, all patients were exposed postoperatively to a cone-beam computed tomography (CBCT) scan. Afterwards, the scans were uploaded into the three-dimensional orthodontic-planning software to allow the volumetric assessment of the palatine suture expansion through palatine rapid maxillary expansion using a McNamara a…
GLI INSETTIVORI DI CAVA MONTICINO (BRISIGHELLA, RA)
2021
Sono note quattro diverse specie di insettivori dalla cava del Monticino, due soricidi (Neomyosorex sp. e cf. Miosorex desnoyersianus) e due erinaceidi (Parasorex depereti e “Mioechinus” sp.). Parasorex depereti appartiene ai Galericini, una tribù estinta di gimnuri, e probabilmente era un animale piuttosto opportunista, come gli altri membri dello stesso genere, forse non legato ad ambienti di foresta o umidi relativamente caldi. “Mioechinus” sp. di collocazione sistematica incerta, per alcuni autori potrebbe essere sinonimo dei generi di ricci moderni Atelerix o Hemiechinus. In questo caso, la sua presenza escluderebbe ambienti desertici o di foresta pluviale. Infine, Neomyosorex sp., rel…
Negotiating a transnational career around borders: Women's stories in boundaryless academia
2021
The study aimed to give voice to two women sport scientists' life stories to centralize the challenges and ways of coping their career journeys entailed, and enlighten our understanding of the lived experience and meaning of academic migrating. They shared transnational career stories through interviews and ongoing conversations which we re-story in a creative non-fiction story where we blended the two. Our data collection, analysis and representation were informed by theoretical, methodological and interpretive bricolage. As the creative non-fiction story shows, the academic entrepreneur ideal was somewhat disrupted in the women's lives, as migration experiences, aside from thrills, also i…
Testing experimental designs in liquid chromatography (II): Influence of the design geometry on the prediction performance of retention models.
2021
Abstract In liquid chromatography, the reliability of predictions carried out with retention models depends critically on the quality of the training experimental design. The search of the best design is more complex when gradient runs are used instead of isocratic experiments. In Part I of this work (JCA 1624 (2020) 461180), a general methodology based on the error propagation theory was developed and validated for assessing the quality of training designs involving gradients. The treatment relates the mathematical properties of a retention model with the geometry of the training designs and their subsequent predictions. In that work, only five usual designs were considered. Part II invest…
ACTIVATION (PercutAneous Coronary inTervention prIor to transcatheter aortic VAlve implantaTION)
2021
Abstract Objectives This study sought to determine if percutaneous coronary intervention (PCI) prior to transcatheter aortic valve replacement (TAVR) in patients with significant coronary artery disease would produce noninferior clinical results when compared with no PCI (control arm). Background PCI in patients undergoing TAVR is not without risk, and there are no randomized data to inform clinical practice. Methods Patients with severe symptomatic aortic stenosis and significant coronary artery disease with Canadian Cardiovascular Society class ≤2 angina were randomly assigned to receive PCI or no PCI prior to TAVR. The primary endpoint was a composite of all-cause death or rehospitalizat…
Total Plasma Exchange for the Management of Thrombotic Thrombocytopenic Purpura in a 13-Year-Old Female – A Case Presentation
2021
Abstract Acquired thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy, affecting preferentially young women in their fourth decade. Intensive care admission is often required due to organ dysfunction development risk and for specific critical care measures (Plasma Exchange-PEX). In this article, we will discuss our experience with PEX in the treatment of TTP. Case report: A previously healthy 13-year-old female presented with neurological impairment, and suspicion of stroke. The head computed tomography (CT) scan revealed absence of acute intracranian pathology, and biological evaluation displayed severe thrombocytopenia and haemolytic anemia. After 24 hours, the …
Potentially Detrimental Effects of Hyperosmolality in Patients Treated for Traumatic Brain Injury
2021
Hyperosmotic therapy is commonly used to treat intracranial hypertension in traumatic brain injury patients. Unfortunately, hyperosmolality also affects other organs. An increase in plasma osmolality may impair kidney, cardiac, and immune function, and increase blood–brain barrier permeability. These effects are related not only to the type of hyperosmotic agents, but also to the level of hyperosmolality. The commonly recommended osmolality of 320 mOsm/kg H2O seems to be the maximum level, although an increase in plasma osmolality above 310 mOsm/kg H2O may already induce cardiac and immune system disorders. The present review focuses on the adverse effects of hyperosmolality on the function…
51P Pooled analysis safety profile of futibatinib in patients with advanced solid tumors, including intrahepatic cholangiocarcinoma (iCCA)
2021
Soft Nodule on the Heel in an Elderly Male Patient: Challenge.
2021
Quality of Life with Voice Prosthesis after Total Laryngectomy.
2021
Introduction: The loss of voice after total laryngectomy is one of the main impairments in personal and social life. In order to prevent potential psycho-social consequences in the patient and his family, the restoration of phonatory function is the main objective of post-laryngectomy rehabilitation. The aim of this study was to assess quality of life in patients who received prosthetic voice after total laryngectomy. Materials and Methods: Over a one-year period, 51 patients with voice prostheses after total laryngectomy were recruited. 32 patients (62.74%) were administered radiation therapy and 9 patients (17.64%) underwent to surgical reconstruction with flaps. Each patient was administ…
Effect of genetic variation in CYP450 on Gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene appr…
2021
Background: Female childhood cancer survivors (CCSs) carry a risk of therapy-related gonadal dysfunction. Alkylating agents (AA) are well-established risk factors, yet inter-individual variability in ovarian function is observed. Polymorphisms in CYP450 enzymes may explain this variability in AA-induced ovarian damage. We aimed to evaluate associations between previously identified genetic polymorphisms in CYP450 enzymes and AA-related ovarian function among adult CCSs. Methods: Anti-Müllerian hormone (AMH) levels served as a proxy for ovarian function in a discovery cohort of adult female CCSs, from the pan-European PanCareLIFE cohort (n = 743
Discourse Markers of French: Multifaceted Look at a Controversial Category
2021
In this paper, we discuss the question of discourse markers (DM) – a category conceived differently by theoretical and applied linguistic approaches. Unlike in applied approaches, in which DMs are considered desemantized/grammaticalized lexical units devoid of their own semantics and therefore of status in the language, we consider DMs to constitute a full-fledged category of language, having its own semantics and distribution, both of which play a crucial role in the construction of discourse (Paillard 2011, 2012; Franckel 2008, 2019). This hypothesis has been developed in theoretical linguistics and has seen little evidence from a perspective of the acquisition and didactics of foreign la…
Les réadmissions après résection pulmonaire en France : la base de données du PMSI
2021
BACKGROUND Readmission within 30 days is an indicator of the quality of care, because it often reflects post-discharge care that is not optimal. The objective of this work is to measure over time on the one hand the readmission rate and on the other hand the number of hospitals with a standardized readmission rate beyond the national average. METHOD All patients with major pulmonary resection for lung cancer in France were extracted from the PMSI national database. Readmission within 30 days was defined as any new hospitalization either in the same hospital or in another establishment. RESULTS From January 1, 2005 to December 31, 2018, 110,603 patients were included. The 30-day all-cause re…
Contribution of local factors to the status of a groundwater dependent terrestrial ecosystem in the transboundary Gauja-Koiva River basin, North-East…
2021
Abstract A pilot study was carried out in the Matsi spring fen, southern Estonia to test a proposed methodology ( Terasmaa et al., 2020 ) for identifying potential effects of groundwater bodies on groundwater dependent terrestrial ecosystems (GDTE). A comprehensive hydrochemical and isotopic dataset was collected and analyzed using multivariate statistical methods to assess the origin of the groundwater discharging in the spring fen and to determine both the quantitative and qualitative aspects of GDTE-groundwater interdependence. The hydrochemical findings were complemented with the hydrogeological, hydrodynamical and botanical observations, and summarized into a conceptual model of the st…
Bentonite-ionic liquid composites for Congo red removal from aqueous solutions
2021
Abstract Clay-organic composites have attracted great interest due to their ability to remove various contaminants from wastewater. The surfactants are the most commonly used organic compounds for clay modification. However, cationic surfactants are toxic and can be environmentally hazardous. Ionic liquids are a new promising alternative to the cationic surfactants due to lesser toxicity and appropriate thermal stability. The research aim is to prepare an environmentally friendly new class of clay sorbents modified with ionic liquids for potential applications in wastewater treatment from the textile industry. Imidazolium-based ionic liquids with different lengths of alkyl chains were inter…
Lilybaeum. Aspetti della vita in una domus al tempo di Cicerone
2021
In a II c. BC house at Marsala (via Sibilla), partially uncovered in the seventies of the last century, an atrium-like room with four central columns was brought to light. The other excavated rooms are paved with opus signinum and white/black mosaics, and some First Style wall painting fragments were recovered above the floors. Other Late Hellenistic houses at Marsala present the same characteristic tetrapyle courtyard. Some scholars consider these courtyards as atria, others as small perystiled courts. To introduce this theme, it’s briefly discussed the s.c. ‘Romanization’. In the particular context of Roman Republican Sicily, the cultural processes started under the Roman rule should not …
Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis
2021
International audience; ERK1/2 involvement in cell death remains unclear, although many studies have demonstrated the importance of ERK1/2 dynamics in determining cellular re- sponses. To untangle how ERK1/2 contributes to two cell death programs, we investigated ERK1/2 signaling dynamics during hFasL-induced apoptosis and TNF-induced necroptosis in L929 cells. We observed that ERK1/2 inhibition sensi- tizes cells to apoptosis while delaying necroptosis. By monitoring ERK1/2 activity by live-cell imaging using an improved ERK1/2 biosensor (EKAR4.0), we reported differential ERK1/2 signaling dynamics between cell survival, apoptosis, and nec- roptosis. We also decrypted a temporally shifted …
Influence of annealing atmosphere on photoelectrochemical response of TiO2 nanotubes anodized under controlled hydrodynamic conditions
2021
[EN] The influence of three annealing atmospheres (air, nitrogen and argon) and the use of controlled hydrodynamic conditions (from 0 to 5000 rpm) on morphological, structural, chemical and photoelectrochemical properties of TiO2 nanotubes have been evaluated. For this purpose, different characterization techniques have been used: Field Emission Scanning Electron Microscopy, Raman Confocal Laser Spectroscopy, X-Ray Diffraction, X-Ray Photoelectron Spectroscopy, Incident Photon-to-electron Conversion Efficiency measurements, ultraviolet-visible absorption spectra, Mott-Schottky analysis and photoelectrochemical water splitting tests. According to the results, it can be concluded that both hy…
Primary Extracranial Meningiomas of the Head and Neck
2021
Meningiomas represent the most common benign histological tumor of the central nervous system. Usually, meningiomas are intracranial, showing a typical dural tail sign on brain MRI with Gadolinium, but occasionally they can infiltrate the skull or be sited extracranially. We present a systematic review of the literature on extracranial meningiomas of the head and neck, along with an emblematic case of primary extracranial meningioma (PEM), which provides further insights into PEM management. A literature search according to the PRISMA statement was conducted from 1979 to June 2021 using PubMed, Web of Science, Google Scholar, and Scopus databases, searching for relevant Mesh terms (primary …
Association between food insecurity and fall-related injury among adults aged ≥65 years in low- and middle-income countries: The role of mental healt…
2021
Purpose:\ud \ud We investigated the association between food insecurity and fall-related injury among older adults from six low- and middle-income countries (LMICs), and the extent to which this association is mediated by mental health.\ud \ud Methods:\ud \ud Cross-sectional, community-based, nationally representative data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Past 12-month food insecurity was assessed with two questions on frequency of eating less and hunger due to lack of food. Fall-related injury referred to those that occurred in the past 12 months. Multivariable logistic regression analysis and mediation analysis were conducted to assess association…
Emotional and Aesthetic Labor of Finnish Military Officers
2021
This study analyzes the emotional and aesthetic labor of Finnish military officers. It examines the kinds of valuations officers attach to the notion of an ideal soldier. The meanings that officers give to these ideals are explored within the wider framework of post-Fordist new work. The ideal soldier is traditionally considered to be physically capable and strong, rational, and in control—features culturally coded as masculine. An analysis of 108 military officers’ writings and 12 interviews showed that while the traditional masculine ideal still exists, a vast variety of valuations are related to new work. The notion of the new ideal worker includes attributes, such as empathy, emotional …
Large-Eddy Simulation e tecnica LS-PIV: lo studio della turbolenza superficiale
2021
Gli avanzamenti tecnologici degli ultimi decenni hanno fatto registrare la rapida diffusione di tecnologie innovative con cui condurre un monitoraggio ambientale più efficiente ed efficace. Nel campo del monitoraggio fluviale sono sempre più utilizzate le tecniche basate sull’elaborazione di immagini, fornendo una valida alternativa alle metodologie tradizionalmente adottate. Le tecniche ottiche restituiscono infatti misure non intrusive, assicurando migliori condizioni di sicurezza per gli operatori. I metodi ottici più utilizzati sono la Large-Scale Particle Image Velocimetry (LS-PIV) [1] e la Large-Scale Particle Tracking Velocimetry (LS-PTV) [2]. Le tecniche LS-PIV e LS-PTV si basano su…
Water absorption and hydrothermal ageing of epoxy adhesives reinforced with amino-functionalized graphene oxide nanoparticles
2021
Abstract The study is focused on quantitative characterization of water absorption and hydrothermal ageing effects in a room-temperature amine cured epoxy adhesive widely used in automotive, aerospace, construction, and marine industries. Amino-functionalized graphene oxide (mGO) nanoparticles were incorporated into the epoxy (up to 1.72 wt.%) enabled cross-linking reactions and providing high interfacial adhesion, superior reinforcement efficiency and enhanced resistance to hydrothermal ageing of nanocomposites. Anomalous water absorption accompanied by progressive weight loss of samples (down to 7%) is fitted by two-stage models considering additive and coupled contribution from water dif…
Spectral Transmission of the Human Corneal Layers
2021
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2077-0383/10/19/4490 Este artículo de investigación pertenece a la sección "Ophthalmology". We have assessed the spectral transmittance of the different layers of the human cornea in the ultraviolet (UV), visible, and near-infrared (IR) spectral ranges. Seventy-four corneal sample donors were included in the study. Firstly, the corneal transmittance was measured using a spectrophotometer. Then, all samples were fixed for histopathological analysis, which allowed us to measure the thickness of each corneal layer. Finally, the absorption coefficients of the corneal layers were computed by a linear model reproducin…
LIODetect®TB-ST: Evaluation of novel blood test for a rapid diagnosis of active pulmonary and extra-pulmonary tuberculosis in IGRA confirmed patients
2021
Abstract Because of the current limits of immunological tests in the diagnosis of tuberculosis there is a need to identify new and rapid tests that can be carried out on a large scale in endemic countries and useful in the identification of infected subjects, but also able to discriminate those with latent infection from subjects with active. We have taken into consideration and analysed the LIODetect®TB-ST Tuberculosis Rapid Test, a membrane test for the qualitative detection of specific IgG, IgA, and IgM antibodies against Mycobacterium tuberculosis, performed on serum, plasma, or whole blood.85 samples positive to QuantiFERON TB-GOLD PLUS test were processed using this test and the resul…
LBA7 Nivolumab (NIVO) plus chemotherapy (Chemo) or ipilimumab (IPI) vs chemo as first-line (1L) treatment for advanced gastric cancer/gastroesophagea…
2021
Restoration of High Frequency Auditory Perception After Robot-Assisted or Manual Cochlear Implantation in Profoundly Deaf Adults Improves Speech Reco…
2021
Background and Purpose: Robot-assisted cochlear implantation has recently been implemented in clinical practice; however, its effect on hearing outcomes is unknown. The aim of this preliminary study was to evaluate hearing performance 1 year post-implantation whether the electrode array was inserted manually or assisted by a robot.Methods: Forty-two profoundly deaf adults were implanted either manually (n = 21) or assisted by a robot (RobOtol®, Collin, Bagneux, France) with three different electrode array types. Participants were paired by age, and electrode array type. The scalar position of the electrode array in the cochlea was assessed by 3D reconstruction from the pre- and post-implant…
Role of peroxiredoxin 6 in the chondroprotective effects of microvesicles from human adipose tissue-derived mesenchymal stem cells
2021
Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.sciencedirect.com/science/article/pii/S2214031X21000656?via%3Dihub Background: Osteoarthritis (OA) is a joint disease characterized by cartilage degradation, low-grade synovitis and subchondral bone alterations. In the damaged joint, there is a progressive increase of oxidative stress leading to disruption of chondrocyte homeostasis. The modulation of oxidative stress could control the expression of inflammatory and catabolic mediators involved in OA. We have previously demonstrated that extracellular vesicles (EVs) present in the secretome of human mesenchymal stem cells from adipose tissu…
BRUNO Pierre, POULOU Bernadette, STUPAR Claudine (dir.), La couleur de l’enfance – Discriminations 2, NVL !, n°229
2021
International audience
Reliability Generalization Study of the Person-Centered Care Assessment Tool
2021
The so-called Person-Centered Care (PCC) model identifies three fundamental principles: changing the focus of attention from the disease to the person, individualizing care, and promoting empowerment. The Person-Centered Care Assessment Tool (P-CAT) has gained wide acceptance as a measure of PCC in recent years due to its brevity and simplicity, as well as its ease of application and interpretation. The objective of this study is to carry out a reliability generalization meta-analysis to estimate the internal consistency of the P-CAT and analyze possible factors that may affect it, such as the year of publication, the care context, the application method, and certain sociodemographic proper…
Book Review: Psicología de la Creatividad. Perspectivas Contemporáneas
2021
This work is the reissue, two decades later, of a book that became a reference for the study of creativity in the Spanish language. The current, renewed, completed and updated editionmaintains the rigor of the previous edition and its direct, personal, and lucid expressive style. The book 'Psicología de la Creatividad. Perspectivas contemporáneas' has an informative character and a scientific basis and offers an analytical approach to the study of creativity from the perspective of psychology, emphasizing the cognitive and motivational dimensions. This is a welcome reissue. It reviews the research literature over the past 12 years and offer an updated version of the state of the art in the …
Flavor Non-universal Pati-Salam Unification and Neutrino Masses
2021
We analyze the neutrino mass spectrum and discuss the extra-dimensional interpretation of a three-site Pati-Salam model which i) unifies all families of quark and leptons, ii) provides a natural description of the Standard Model Yukawa couplings, iii) could account for the recent $B$-physics anomalies. The key feature of the model is a breaking of the Pati-Salam and electroweak gauge symmetries localized on opposite sites, communicated to the other sites in an attenuated manner via nearest-neighbor interactions. We show that in this context gauge-singlet fermions localized on each site, receiving hierarchical Majorana masses, can allow the implementation of an inverse seesaw mechanism leadi…