showing 36 of ~574560 from 574555 documents
Effects of training on bone metabolism in young athletes
2021
Purpose. This study investigated the effects of two types of training on the bone formation marker of osteocalcin and the bone resorption marker of tartrate-resistant acid phosphatase isoenzyme 5b (TRAP5b) in young track and field boys and girls. Methods. The 14-year-old group (10 boys, 10 girls) performed first time an intensive and supervised 8-week plyometric training. In the 17-year-old group (13 athletic boys, 6 control boys, 12 athletic girls, 6 control girls), the normal many-sided track and field training lasted 6 months. Results. Significant increases were noticed in osteocalcin (p < 0.01) both in younger boys and girls. The 20-m sprint performance improved in girls (p < 0.01) and …
Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection
2021
Murine models of cytomegalovirus (CMV) infection have revealed an immunological phenomenon known as “memory inflation” (MI). After a peak of a primary CD8+ T-cell response, the pool of epitope-specific cells contracts in parallel to the resolution of productive infection and the establishment of a latent infection, referred to as “latency.” CMV latency is associated with an increase in the number of cells specific for certain viral epitopes over time. The inflationary subset was identified as effector-memory T cells (iTEM) characterized by the cell surface phenotype KLRG1+CD127−CD62L−. As we have shown recently, latent viral genomes are not transcriptionally silent. Rather, viral genes are …
Adolescence, Adulthood and Self-Perceived Halitosis: A Role of Psychological Factors
2021
(1) Background: Halitosis is a frequent condition that affects a large part of the population. It is considered a “social stigma”, as it can determine a number of psychological and relationship consequences that affect people’s lives. The purpose of this review is to examine the role of psychological factors in the condition of self-perceived halitosis in adolescent subjects and adulthood. (2) Type of studies reviewed: We conducted, by the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) guidelines, systematic research of the literature on PubMed and Scholar. The key terms used were halitosis, halitosis self-perception, psychological factors, breath odor and two te…
Isokinetic Profile of Elite Serbian Female Judoists
2021
Elite judo athletes undergo vigorous training to achieve outstanding results. In pursuit of achieving competitive success, the occurrence of injuries amongst judo athletes is not rare. The study aimed to perform a knee flexors and extensors isokinetic torque analysis in elite female judo athletes. Fifty-eight elite female judo athletes of the Serbian national team (21.02 ± 3.11 years
Analyse des discours autour du Dépistage Néonatal sur Twitter dans le cadre du Projet SeDeN
2021
Subclinical Cardiotoxicity: The Emerging Role of Myocardial Work and Other Imaging Techniques.
2021
In recent years, the cancer survival of patients has improved thanks to advances in the pharmacological field. In many guidelines, cardiotoxicity induced by anticancer drugs was defined as a reduction from baseline in the left ventricular ejection fraction (LVEF) assessed by echocardiography. It is known that LVEF is not a sensible parameter in the detection of cardiotoxicity. Therefore, a decrease from baseline in the global longitudinal strain (GLS) or troponins elevation is used to detect subclinical cardiotoxicity. LVEF and GLS as well as the increase in some biomarkers are influenced by loading conditions that are frequent during chemotherapy. Other parameters not influenced by loading…
Precision exercise medicine: predicting unfavourable status and development in the 20-m shuttle run test performance in adolescence with machine lear…
2021
Objectives: To assess the ability to predict individual unfavourable future status and development in the 20m shuttle run test (20MSRT) during adolescence with machine learning (random forest (RF) classifier). Methods: Data from a 2-year observational study (2013‒2015, 12.4±1.3 years, n=633, 50% girls), with 48 baseline characteristics (questionnaires (demographics, physical, psychological, social and lifestyle factors), objective measurements (anthropometrics, fitness characteristics, physical activity, body composition and academic scores)) were used to predict: (Task 1) unfavourable future 20MSRT status (identification of individuals in the lowest 20MSRT tertile after 2 years), and (Task…
The influence of the Covid-19 pandemic on Czech-Polish cross-border cooperation: From debordering to re-bordering?
2021
Abstract The COVID-19 pandemic brought many changes to social behaviours in Europe. One of its major consequences was the temporary closure of borders, which was introduced as a measure to prevent the uncontrolled pandemic spreading and involved internal Schengen borders. This has had a major impact in the way in which cross-border cooperation has been conducted in Europe, including the Czech-Polish borderland, as it dramatically restrained all flows across borders. In this paper, we evaluate the impact of the pandemic on five roles of cross-border cooperation: 1) as a multi-level governance form; 2) as a regional development tool; 3) as a para-diplomacy form; 4) as a post-conflict reconcil…
The antimicrobial activity of honey and propolis extracts from the central region of Romania
2021
Abstract Honey and propolis from Apis mellifera (bees) are products that have been used due to their multiple biological properties. The antimicrobial activity of 10 honey samples of known origin and 4 propolis extracts gathered from the same beekeepers located in Transylvania, Romania, were used against certain microorganisms: Escherichia coli, Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa and Candida albicans. The study also investigated the positive interaction of propolis aqueous extracts when used with poly-floral honey against the same microorganisms. The most sensitive to the activity of honey samples was the S. aureus strain (the largest inhibition area 18 mm) for p…
A hybrid virtual–boundary element formulation for heterogeneous materials
2021
Abstract In this work, a hybrid formulation based on the conjoined use of the recently developed Virtual Element Method (VEM) and the Boundary Element Method (BEM) is proposed for the effective computational analysis of multi-region domains, representative of heterogeneous materials. VEM has been recently developed as a generalisation of the Finite Element Method (FEM) and it allows the straightforward employment of elements of general polygonal shape, maintaining a high level of accuracy. For its inherent features, it allows the use of meshes of general topology, including non-convex elements. On the other hand, BEM is an effective technique for the numerical solution of sets of boundary i…
Potential of Antifungal Proteins (AFPs) to Control Penicillium Postharvest Fruit Decay
2021
Penicillium phytopathogenic species provoke severe postharvest disease and economic losses. Penicillium expansum is the main pome fruit phytopathogen while Penicillium digitatum and Penicillium italicum cause citrus green and blue mold, respectively. Control strategies rely on the use of synthetic fungicides, but the appearance of resistant strains and safety concerns have led to the search for new antifungals. Here, the potential application of different antifungal proteins (AFPs) including the three Penicillium chrysogenum proteins (PAF, PAFB and PAFC), as well as the Neosartorya fischeri NFAP2 protein to control Penicillium decay, has been evaluated. PAFB was the most potent AFP against …
Occurrence, mitigation and in vitro cytotoxicity of nivalenol, a type B trichothecene mycotoxin - Updates from the last decade (2010-2020).
2021
Abstract The present review aims to give an overview of the literature of the last decade (2010–2020) concerning the occurrence of the type B trichothecene mycotoxin nivalenol (NIV) and its in vitro toxicity, with the purpose of updating information regarding last researches on this mycotoxin. The most recent studies on the possible methods for preventing Fusarium spp. growth and NIV production are also discussed. Recently, various environmental factors have been shown to influence strongly NIV occurrence. However, Fusarium spp. of the NIV genotype have been found almost worldwide. With regard to NIV cytotoxicity, NIV has been reported to cause a marked decrease in cell proliferation in dif…
NQS-Doped PDMS Solid Sensor: From Water Matrix to Urine Enzymatic Application
2021
The development of in situ analytical devices has gained outstanding scientific interest. A solid sensing membrane composed of 1,2-naphthoquinone-4-sulfonate (NQS) derivatizing reagent embedded into a polymeric polydimethylsiloxane (PDMS) composite was proposed for in situ ammonium (NH4+) and urea (NH2CONH2) analysis in water and urine samples, respectively. Satisfactory strategies were also applied for urease-catalyzed hydrolysis of urea, either in solution or glass-supported urease immobilization. Using diffuse reflectance measurements combined with digital image processing of color intensity (RGB coordinates), qualitative and quantitative analyte detection was assessed after the colorime…
Advanced glycation end products measured by skin autofluorescence are associated with melancholic depressive symptoms - Findings from Helsinki Birth …
2021
Background: Millions of people live with depression and its burden of disease. Depression has an increased comorbidity and mortality that has remained unexplained. Studies have reported connections between advanced glycation end products (AGEs) and various disease processes, including mental health. The present study evaluated associations between AGEs, depressive symptoms, and types of depressive symptoms. Methods: From the Helsinki Birth Cohort Study, 815 participants with a mean age of 76 years were recruited for this cross-sectional study. Characteristics regarding self-reported lifestyle and medical history, as well as blood tests were obtained along with responses regarding depressive…
Clinicopathological Significance of Syndecan-1 in Cholangiocarcinoma: A Study Based on Immunohistochemistry and Public Sequencing Data
2021
Background: Syndecan-1 (CD138
Sexual conflict drives micro- and macroevolution of sexual dimorphism in immunity
2021
Abstract Background Sexual dimorphism in immunity is believed to reflect sex differences in reproductive strategies and trade-offs between competing life history demands. Sexual selection can have major effects on mating rates and sex-specific costs of mating and may thereby influence sex differences in immunity as well as associated host–pathogen dynamics. Yet, experimental evidence linking the mating system to evolved sexual dimorphism in immunity are scarce and the direct effects of mating rate on immunity are not well established. Here, we use transcriptomic analyses, experimental evolution and phylogenetic comparative methods to study the association between the mating system and sexua…
Thermal Index for early non-invasive assessment of brain injury in newborns treated with therapeutic hypothermia: preliminary report.
2021
AbstractPerinatal asphyxia (PA) is the 3rd most common cause of neonatal death and one of the most common causes of severe neurological impairments in children. Current tools and measurements mainly based on the analysis of clinical evaluation and laboratory and electrophysiological tests do not give consistent data allowing to predict the severity of hypoxic-ischemic encephalopathy (HIE) until a magnetic resonance imaging (MRI) score is performed. The aim of this work is to evaluate the usefulness of the new index, called Thermal Index (TI) in the assessment of the degree of brain damage in newborns in the course of therapeutic hypothermia (TH) due to PA. This was a prospective, observatio…
Presentazione dell’edizione italiana di storia della Sicilia da Odisseo ai giorni nostri di Jean-Yves Frétigné
2021
Published for the first time in 2009, for the Fayard types, and re-edited in 2018 in a "pocket" format, this History of Sicily by Jean-Yves Frétigné, with the subtitle from Odysseus to the present day, presented to the French public as an easy consultation, a "Compagnon de voyage" destined to have an excellent editorial success with over 8,000 copies sold.The Italian translation presented here does not have the presumption of concurring with the monumental works of the history of Sicily which constitute an essential reference by the same Author, as the rich bibliography in the appendix to the volume clearly testifies. Rather, it intends to offer, in just over 400 pages, the “external” look …
Halévy, fugue d’école und basse donnée
2021
Fuge als satztechnische Ubung – nach Cherubini die ideale Verbindung von strengem Kontrapunkt und freier Komposition – gehorte im 19. Jahrhundert an nahezu allen musikalischen Ausbildungsinstitutionen zum Standardrepertoire, so auch am Conservatoire de Paris: Die Wettbewerbsfugen zum Prix de Rome zeugen vom hohen Niveau der Ausbildung, auch wenn sich die kontrapunktische Ubung immer deutlicher von der kompositorischen Asthetik der Schreibenden entfernte. Anhand von Arbeiten Fromental Halevys wird dieses Niveau aufgezeigt. Dabei kommt sowohl der Schuler Halevy, der seine Wettbewerbsfuge 1819 unter dem Auge Cherubinis verfasste, zu Wort als auch der Lehrer Halevy, dessen Schulerarbeiten einen…
Antoine Traisnel, Capture: American Pursuits and the Making of a New Animal Condition
2021
You can’t judge a book by its cover. Or so they say. But the cover of Antoine Traisnel’s Capture: American Pursuits and the Making of a New Animal Condition is striking and, one is tempted to say, captivating. And so is the book. The cover features colorful images of various birds—such as the ruby-throated hummingbird, the tufted coquette or the buff-tailed sicklebill—taken from one of the most impressive plates in Ernst Haeckel’s Kunstformen der Natur (Art Forms in Nature) and interlaced on ...
A geostatistical approach to map near-surface soil moisture through hyperspatial resolution thermal inertia.
2021
Thermal inertia has been applied to map soil water content exploiting remote sensing data in the short and long wave regions of the electromagnetic spectrum. Over the last years, optical and thermal cameras were sufficiently miniaturized to be loaded onboard of unmanned aerial systems (UASs), which provide unprecedented potentials to derive hyperspatial resolution thermal inertia for soil water content mapping. In this study, we apply a simplification of thermal inertia, the apparent thermal inertia (ATI), over pixels where underlying thermal inertia hypotheses are fulfilled (unshaded bare soil). Then, a kriging algorithm is used to spatialize the ATI to get a soil water content map. The pr…
Publisher's Note: “Attosecond state-resolved carrier motion in quantum materials probed by soft x-ray XANES” [Appl. Phys Rev. 8, 011408 (2021)]
2021
Recent developments in attosecond technology led to table-top x-ray spectroscopy in the soft x-ray range, thus uniting the element- and state-specificity of core-level x-ray absorption spectroscopy with the time resolution to follow electronic dynamics in real-time. We describe recent work in attosecond technology and investigations into materials such as Si, SiO2, GaN, Al2O3, Ti, and TiO2, enabled by the convergence of these two capabilities. We showcase the state-of-the-art on isolated attosecond soft x-ray pulses for x-ray absorption near-edge spectroscopy to observe the 3d-state dynamics of the semi-metal TiS2 with attosecond resolution at the Ti L-edge (460 eV). We describe how the ele…
Fuzzy-set Qualitative Comparative Analysis (fsQCA): Guidelines for research practice in Information Systems and marketing
2021
Abstract The increasing interest in fuzzy-set Qualitative Comparative Analysis (fsQCA) in Information Systems and marketing raises the need for a tutorial paper that discusses the basic concepts and principles of the method, provide answers to typical questions that editors, reviewers, and authors would have when dealing with a new tool of analysis, and practically guide researchers on how to employ fsQCA. This article helps the reader to gain richer information from their data and understand the importance of avoiding shallow information‐from‐data reporting. To this end, it proposes a different research paradigm that includes asymmetric, configurational‐focused case‐outcome theory construc…
Evaluation of 6 biometers based on different optical technologies
2021
This study shows that optical biometers based on different technologies provide repeatable measurements for different ocular parameters and, when compared, statistically significant differences between them were found when measuring most parameters.
VOLUMETRIC BEHAVIOUR OF SOILS EXPERIENCING WIDE CHANGES IN THE DEGREE OF SATURATION
2021
DEDICA
2021
ITALIAN TRANSLATION OF N. VRETTAKOS' "AFIEROMA”
Data mining, dashboards and statistics: a powerful framework for the chemical design of molecular nanomagnets
2021
Abstract Three decades of intensive research in molecular nanomagnets have brought the magnetic memory in molecules from liquid helium to liquid nitrogen temperature. The enhancement of this operational temperature relies on a wise choice of the magnetic ion and the coordination environment. However, serendipity, oversimplified theories and chemical intuition have played the main role. In order to establish a powerful framework for statistically driven chemical design, we collected chemical and physical data for lanthanide-based nanomagnets to create a catalogue of over 1400 published experiments, developed an interactive dashboard (SIMDAVIS) to visualise the dataset, and applied inferentia…
Educational dialogue among teachers experiencing different levels of self-efficacy
2021
This study examines the occurrence and quality of educational dialogue in the Grade 1 classrooms of teachers with low, moderate and high self-efficacy beliefs. Video recordings of 24 teachers were analysed based on episodes of educational dialogue and were categorised with respect to patterns of dialogic teaching. Teachers with low levels of self-efficacy conducted educational dialogue the least; they also used less teacher-initiated, high-quality dialogue compared with moderate and high self-efficacy teachers. Teachers with high self-efficacy utilised more child-initiated high-quality dialogue compared with the moderate self-efficacy teachers. The findings are important because they provid…
La thèse en CIFRE : les tenants et les aboutissants en sciences humaines et sociales
2021
International audience; Cette intervention visait à expliquer les tenants et les aboutissants d’une thèse CIFRE en sciences humaines et sociales, de la candidature à sa concrétisation. Elle expliquait aussi les défis qu’ont les doctorants en CIFRE pour l’élaboration de la méthodologie, la mise en place du terrain et la posture à adopter vis-à-vis de ce statut particulier entre université et exigences du milieu professionnel.
Inter-annotator agreement in spoken language annotation: Applying uα-family coefficients to discourse segmentation
2021
As databases make Corpus Linguistics a common tool for most linguists, corpus annotation becomes an increasingly important process. Corpus users do not need only raw data, but also annotated data, submitted to tagging or parsing processes through annotation protocols. One problem with corpus annotation lies in its reliability, that is, in the probability that its results can be replicable by independent researchers. Inter-annotation agreement (IAA) is the process which evaluates the probability that, applying the same protocol, different annotators reach similar results. To measure agreement, different statistical metrics are used. This study applies IAA for the first time to the Valencia E…
Evaluation of near-Infrared fluorescence-conjugated peptides for visualization of human epidermal receptor 2-overexpressed gastric cancer.
2021
338 Background: HER2 is highly overexpressed in many kinds of cancers with a poor prognosis. Recently, near-infrared (NIR) fluorescence-based imaging is a growing field for both pre-clinical and clinical application. In this study, we aimed to synthesize Human Epidermal Receptor2 (HER2)-specific near-infrared (NIR) fluorescence probes and evaluate their applicability in cancer-specific image-guided surgeries using an animal model. Methods: An NIR dye emitting light of 800 nm (IRDye800CW, Li-COR, USA) was conjugated to trastuzumab and HER2-specific affibody using click mechanism. HER2 affinity was assessed by the surface plasmon resonance technique. HER2 positive/negative gastric cancer cel…
At the temporary-permanent interface: Overcoming knowledge boundaries with boundary objects
2021
Abstract There is no shortage of literature on managing complex projects. However, we lack an understanding of projects in which the complexity goes beyond technical, financial and time-related challenges. We report on two Nordic business school accreditation projects, where the major management challenge is the knowledge boundaries institutionalized deep into the ethos of the schools. We focus on the project team’s use of boundary objects – a communication device across social groups – to expose and overcome knowledge boundaries materializing at temporary-permanent interface. We identify three progressively more challenging boundary object uses: informative, interactive and integrative. Co…
Body Mass Index and Risk for Intubation or Death in SARS-CoV-2 Infection
2021
Self-assembled metal-oxide nanoparticles on GaAs: infrared absorption enabled by localized surface plasmons
2021
Abstract Metal-oxides hold promise as superior plasmonic materials in the mid-infrared compared to metals, although their integration over established material technologies still remains challenging. We demonstrate localized surface plasmons in self-assembled, hemispherical CdZnO metal-oxide nanoparticles on GaAs, as a route to enhance the absorption in mid-infrared photodetectors. In this system, two localized surface plasmon modes are identified at 5.3 and 2.7 μm, which yield an enhancement of the light intensity in the underlying GaAs. In the case of the long-wavelength mode the enhancement is as large as 100 near the interface, and persists at depths down to 50 nm. We show numerically t…
The entangled multi-level responses of Mytilus galloprovincialis (Lamarck, 1819) to environmental stressors as detected by an integrated approach.
2021
Abstract Anthropogenic pressure adds up and interacts with the effects of climate change with a varying magnitude and potential changes depend on species’ Life History (LH) traits, local environmental conditions and co-occurrence of several stressors. Stressors exert negative effects on marine biota when acting as a single factor, but the effects may be amplified when more than one stressor work in combination, producing interacting effects on biodiversity and ecosystem functioning. The impairment of individual functional traits (FT) leads to strong rebounds on LH traits and this may have ecological consequences. No studies actually relate FT and antioxidant enzymes to multiple environmenta…
Salmon (Salmo salar) side streams as a bioresource to obtain potential antioxidant peptides after applying pressurized liquid extraction (PLE)
2021
The pressurized liquid extraction (PLE) technique was used to obtain protein extracts with antioxidant capacity from salmon muscle remains, heads, viscera, skin, and tailfins. A protein recovery percentage ≈28% was obtained for all samples except for viscera, which was ≈92%. These values represented an increase of 1.5–4.8-fold compared to stirring extraction (control). Different SDS-PAGE profiles in control and PLE extracts revealed that extraction conditions affected the protein molecular weight distribution of the obtained extracts. Both TEAC (Trolox equivalent antioxidant capacity) and ORAC (oxygen radical antioxidant capacity) assays showed an outstanding antioxidant activity for viscer…