showing 36 of ~574560 from 574555 documents
Making Sociologically-Grounded Fictions. A Review of the Sociorama Collection Experience
2021
As members of the scientific committee of a collection of sociological comic strips, we offer feedback here on our experience of translating qualitative sociological research into graphic fictions. Through the presentation of main editorial choices and the organization of the adaptation work, we explain and discuss the effects produced by this type of adaptation on sociological discourse. We present a “lesson learned” from this adaptation process that disrupted and challenged the inherent assumptions of academic sociological writing. This review of Sociorama albums highlights some advantages and successes, as well as some limitations and obstacles introduced by this comic-ization.
Proximité cognitive et responsabilité sociétale des organisations publiques : le cas des établissements publics placés sous tutelle
2021
International audience
The conjugation strategy affects antibody orientation and targeting properties of nanocarriers.
2021
Antibody-modified drug delivery systems in the nano-range have the ability to overcome current challenges for treating diseases due to their high specificity towards the targeted body region. However, no antibody-bound nanocarrier has been clinically approved to date. This missing clinical approval may be a result of the conjugation strategy that influences the spatial orientation of the attached antibody on the nanocarriers' surface. What is not missing, however, is a diverse selection of antibody to nanocarrier conjugation strategies that determine the success of an antibody functionalized drug delivery system. In this paper, two antibody conjugation strategies were compared by conjugatin…
Lipid Composition Analysis Reveals Mechanisms of Ethanol Tolerance in the Model Yeast Saccharomyces cerevisiae
2021
Saccharomyces cerevisiae is an important unicellular yeast species within the biotechnological and the food and beverage industries. A significant application of this species is the production of ethanol, where concentrations are limited by cellular toxicity, often at the level of the cell membrane. Here, we characterize 61 S. cerevisiae strains for ethanol tolerance and further analyze five representatives with various ethanol tolerances. The most tolerant strain, AJ4, was dominant in coculture at 0 and 10% ethanol. Unexpectedly, although it does not have the highest noninhibitory concentration or MIC, MY29 was the dominant strain in coculture at 6% ethanol, which may be linked to differen…
Symbiont Genomic Features and Localization in the Bean Beetle Callosobruchus maculatus
2021
A pervasive pest of stored leguminous products, the bean beetle Callosobruchus maculatus (Coleoptera: Chrysomelidae) associates with a simple bacterial community during adulthood. Despite its economic importance, little is known about the compositional stability, heritability, localization, and metabolic potential of the bacterial symbionts of C. maculatus. In this study, we applied community profiling using 16S rRNA gene sequencing to reveal a highly conserved bacterial assembly shared between larvae and adults. Dominated by Firmicutes and Proteobacteria, this community is localized extracellularly along the epithelial lining of the bean beetle's digestive tract. Our analysis revealed that…
Automated detection and classification of synoptic scale fronts from atmospheric data grids
2021
<p>Automatic determination of fronts from atmospheric data is an important task for weather prediction as well as for research of synoptic scale phenomena. We developed a deep neural network to detect and classify fronts from multi-level ERA5 reanalysis data. Model training and prediction is evaluated using two different regions covering Europe and North America with data from two weather services. Due to a label deformation step performed during training we are able to directly generate frontal lines with no further thinning during post processing. Our network compares well against the weather service labels with a Critical Success Index higher than 66.9% and a Object Detecti…
Tourist behaviour: the essential companion
2021
It is noteworthy to say to readers that Phillip Pearce is doubtless an authoritative voice in the psychology of tourism. On this occasion, he edits a book which entitles Tourist Behaviour: the esse...
Dimensional and Discrete Emotional Reactivity in Alzheimer’s Disease: Film Clips as a Research Tool in Dementia
2021
Background: No studies have been conducted to date on the dimensional and discrete classification of emotions to study the emotional reactivity of older adults with Alzheimer’s disease (AD). Additionally, the presentation of film clips with affective content is currently one of the most effective and widely used Mood Induction Procedures (MIPS). However, it has been scarcely used in AD patients. Objective: Based on the dimensional and discrete models of emotion, this study examines the emotional reactivity of older adults with AD, using a popular set of film clips to induce emotions. Methods: We compared the responses of older adults aged over 65-years with mild to moderate AD (n = 15) and …
Chronic kidney disease and dialysis therapy: incidence and prevalence in the world
2021
Сhronic kidney disease (CKD) is the important public and medical problem in the world because of a large burden on health care systems. The prevalence of CKD and number of dialysis patients are increasing in the world. The prevalence and incidence of CKD depends on age, race, and gender of patients, region, and the presence of the CKD registry in a country. Diabetes mellitus (DM) and arterial hypertension (AH) are the most common causes of end stage renal disease (ESRD). It is projected that the number of dialysis patients will reach 5.5 million in 2030. Specific strategies and interventions should be urgently aimed at reducing in the burden of CKD by means of the prevention, detection and …
Health communication in covid-19 era: Experiences from the italian vaccinarsì network websites
2021
In 2013, in a bid to combat Vaccine Hesitancy (VH) and provide information on vaccines by communicating with the general public and the health community (e.g., healthcare workers and public health operators), the Italian Society of Hygiene and Preventive Medicine (S.It.I.) published the national website “VaccinarSì”. The project was subsequently extended to ten Italian Regions. This led to the creation of the VaccinarSì Network, whose websites are publicly owned. The aim of this work was to present the framework of the websites of the VaccinarSì Network and to analyse user behaviour in the pre-COVID-19-era (dating from each website’s publication until 31 January 2020) and in the COVID-19-er…
The role of PET radiomic features in prostate cancer: a systematic review
2021
Aim: This systematic review aims to present the available evidence on the use of radiomic features (RFs) extracted from PET imaging in patients with prostate cancer (PCa). Materials and methods: A comprehensive literature search of studies on the utility of PET-derived RFs in patients with PCa was performed in the PubMed/MEDLINE database through February 24th, 2021 using the following search string: [“positron-emission tomography” (MeSh terms) OR “positron emission tomography computed tomography” (MeSh terms) OR “positron-emission tomography” (all fields) OR “positron emission tomography computed tomography” (all fields) OR “PET” (all fields)] AND [“radiomics” (all fields) OR “radiomic” (al…
Selective Synthesis of Z -Silyl Enol Ethers via Ni-Catalyzed Remote Functionalization of Ketones
2021
Journal of the American Chemical Society : JACS 143(22), 8375-8380 (2021). doi:10.1021/jacs.1c01797
Profit, morality and discrimination
2021
Using an original vignette survey, we study the normative acceptability of the trade-off between immoral profit (discrimination) and costly morality (non-discrimination). We test the causal influen...
Omni-Channel Intensity and Shopping Value as Key Drivers of Customer Satisfaction and Loyalty
2021
Omni-channel retailing consists of the complete alignment of the different channels and touchpoints that generate a seamless experience for consumers, allowing them to move freely through all channels. The consumer's perception of a seamless and consistent omni-channel experience is called intensity. This study reveals that this intensity in the shopping experience can offer value to consumers, and that intensity and shopping value also influence satisfaction and loyalty. We propose a relationship model that had been tested in a quantitative study with PLS, with a representative sample of buyers who had used the Click and Collect system. The main contribution of this study is to the literat…
Abstract MP04: Taste Perception Profiles Are Associated With Patterns Of Adherence To A Mediterranean Diet Among Older Adults With Metabolic Syndrome
2021
Objective: Evidence suggests perception of sweet, salt, sour, bitter, and umami tastes may be independently related to food preferences and intake. Our objective was to determine whether a collective measure of taste perception for all 5 tastes—“taste perception profiles”—was related to adherence to a Mediterranean diet (MedD). Methods: Participants were 367 older adults (55-75 years; 55% female) with metabolic syndrome from PREDIMED-Plus, Valencia. A data-driven clustering approach identified six taste perception profiles from baseline taste perception scores: Low All ( n = 85), High Bitter ( n = 41), High Umami ( n = 61), Low Bitter & Umami ( n = 59), High All But Bitter ( n = 72) an…
Energy Recovery of Multiple Charge Sharing Events in Room Temperature Semiconductor Pixel Detectors
2021
Multiple coincidence events from charge-sharing and fluorescent cross-talk are typical drawbacks in room-temperature semiconductor pixel detectors. The mitigation of these distortions in the measured energy spectra, using charge-sharing discrimination (CSD) and charge-sharing addition (CSA) techniques, is always a trade-off between counting efficiency and energy resolution. The energy recovery of multiple coincidence events is still challenging due to the presence of charge losses after CSA. In this work, we will present original techniques able to correct charge losses after CSA even when multiple pixels are involved. Sub-millimeter cadmium–zinc–telluride (CdZnTe or CZT) pixel detectors we…
Social sensitivity:a manifesto for CSCL research
2021
International audience; Technologies for computer-supported collaborative learning (CSCL) are playing an increasingly prominent role in educational contexts, especially as teachers and students strive to deal with pandemic-related constraints. However, the technologies being used for collaboration on a daily basis are not sufficiently equipped to promote collaborative learning as both a cognitive and a socio-emotional process. They may even run the risk of hindering the constructive exchange of ideas and provoking disputes and negative encounters. In this squib, we argue that the field of CSCL is failing to address this risk, because our research efforts are far too scattered and siloed. We…
Understanding the implication of autophagy in the activation of hepatic stellate cells in liver fibrosis: are we there yet?
2021
Liver fibrosis (LF) occurs as a result of persistent liver injury and can be defined as a pathologic, chronic, wound-healing process in which functional parenchyma is progressively replaced by fibrotic tissue. As a phenomenon involved in the majority of chronic liver diseases, and therefore prevalent, it exerts a significant impact on public health. This impact becomes even more patent given the lack of a specific pharmacological therapy, with LF only being ameliorated or prevented through the use of agents that alleviate the underlying causes. Hepatic stellate cells (HSCs) are fundamental mediators of LF, which, activated in response to pro-fibrotic stimuli, transdifferentiate from a quies…
Spanish Studies: History of Spanish Linguistics
2021
Acoustic Topological Circuitry in Square and Rectangular Phononic Crystals
2021
International audience; We systematically engineer a series of square and rectangular phononic crystals to create experimental realizations of complex topological phononic circuits. The exotic topological transport observed is wholly reliant upon the underlying structure which must belong to either a square or rectangular lattice system and not to any hexagonal-based structure. The phononic system chosen consists of a periodic array of square steel bars which partitions acoustic waves in water over a broadband range of frequencies (∼0.5MHz). An ultrasonic transducer launches an acoustic pulse which propagates along a domain wall, before encountering a nodal point, from which the acoustic si…
Biodiversité : la commune accueille un projet de recherche europeen
2021
National audience
Mitigation of backgrounds from cosmogenic 137Xe in xenon gas experiments using 3He neutron capture
2021
136Xe is used as the target medium for many experiments searching for 0¿ßß. Despite underground operation, cosmic muons that reach the laboratory can produce spallation neutrons causing activation of detector materials. A potential background that is difficult to veto using muon tagging comes in the form of 137Xe created by the capture of neutrons on 136Xe. This isotope decays via beta decay with a half-life of 3.8 min and a Q ß of ~4.16 MeV. This work proposes and explores the concept of adding a small percentage of 3He to xenon as a means to capture thermal neutrons and reduce the number of activations in the detector volume. When using this technique we find the contamination from 137Xe …
Analyzing environmental‐trait interactions in ecological communities with fourth‐corner latent variable models
2021
In ecological community studies it is often of interest to study the effect of species related trait variables on abundances or presence-absences. Specifically, the interest may lay in the interactions between environmental and trait variables. An increasingly popular approach for studying such interactions is to use the so-called fourth-corner model, which explicitly posits a regression model where the mean response of each species is a function of interactions between covariate and trait predictors (among other terms). On the other hand, many of the fourth-corner models currently applied in the literature are too simplistic to properly account for variation in environmental and trait resp…
Evaluation of the MGDRx eyebag treatment in young and older subjects with dry eye symptoms
2021
Summary Objectives This study aims to evaluate the relationship between application of the MGDRx thermal eyebag and dry eye signs and symptoms in young and older subjects and to compare the results between the two groups. Methods Thirty young, healthily volunteers between 18 and 31 years of age (23.95 ± 3.94 years) and thirty older subjects between 61 and 90 years of age (77.97 ± 8.11 years) participated in this study. Ocular surface parameters were assessed using the Oculus Keratograph 5 M, following the guidelines of the Tear Film and Ocular Surface Dry Eye Workshop II Diagnostic Methodology report. Only subjects with a positive score on at least one questionnaire and an initial Non-Invas…
The maximum carbonyl ratio (MCR) as a new index for the structural classification of secondary organic aerosol components
2021
RATIONALE Organic aerosols (OA) account for a large fraction of atmospheric fine particulate matter and thus are affecting climate and public health. Elucidation of the chemical composition of OA is the key for addressing the role of ambient fine particles at the atmosphere-biosphere interface and mass spectrometry is the main method to achieve this goal. METHODS High-resolution mass spectrometry (HRMS) is on its way to becoming one of the most prominent analytical techniques, also for the analysis of atmospheric aerosols. The combination of high mass resolution and accurate mass determination allows the elemental compositions of numerous compounds to be easily elucidated. Here a new parame…
Geographical Variability in Mortality in Urban Areas: A Joint Analysis of 16 Causes of Death.
2021
The authors acknowledge the support of the research grants PI16/00670, PI16/00755, PI16/01004, PI16/01187, PI16/01273, PI16/01281, and PI18/01313 of Instituto de Salud Carlos III, co-funded with FEDER grants.
Bagatelles pour un massacre de Louis-Ferdinand Céline à l’épreuve du droit pénal français actuel : une réédition impossible ?
2021
Doctrine; International audience
Direct Evidence of Heteroleptic Complexation in the Macroscopic Dynamics of Metallo-supramolecular Polymer Networks
2021
Impact of daytime routine modifications on people with severe intellectual disability amid COVID‐19 pandemic
2021
Event-Based Trajectory Prediction Using Spiking Neural Networks
2021
International audience; In recent years, event-based sensors have been combined with spiking neural networks (SNNs) to create a new generation of bio-inspired artificial vision systems. These systems can process spatio-temporal data in real time, and are highly energy efficient. In this study, we used a new hybrid event-based camera in conjunction with a multi-layer spiking neural network trained with a spike-timing-dependent plasticity learning rule. We showed that neurons learn from repeated and correlated spatio-temporal patterns in an unsupervised way and become selective to motion features, such as direction and speed. This motion selectivity can then be used to predict ball trajectory…
Exposure to nanoparticles in thermal spraying - Vigilance towards the operator and the outside environment
2021
International audience; The previous survey of the French CaRPE project has shown a lack of information and showed the interest to assess the residual exposure to these particles. This paper presents the results of various sampling operations and emission analyses of plasma spraying equipment. For this purpose, different areas have been targeted, such as at the level of the emissions channeled upstream and downstream of the filtration system, at the workstation level as well as fugitive emissions. Various measurements were carried out: real-time particle size distribution, mass concentration of total suspended dust, heavy metals, sampling characterization by EDX/ MET, etc. The metallic aero…
Magnetism-mediated transition between crystalline and higher-order topological phases in NpSb
2021
Merging the fields of topology and magnetism expands the scope of fundamental quantum phenomena with novel functionalities for topological spintronics enormously. Here, we theoretically demonstrate that ferromagnetism provides an efficient means to achieve a topological switching between crystalline and higher-order topological insulator phases in two dimensions. Using a tight-binding model and first-principles calculations, we identify layered NpSb as a long-awaited two-dimensional topological crystalline insulator with intrinsic ferromagnetic order with a band gap which is as large as 220 meV. We show that when ${\mathcal{M}}_{z}$ symmetry is preserved for the out of plane magnetization o…
Amplitude analysis and branching-fraction measurement of Ds+→KS0K−π+π+
2021
Using 6.32 fb−1 of e+e− collision data collected by the BESIII detector at the center-of-mass energies between 4.178 and 4.226 GeV, an amplitude analysis of the D+s → K0SK−π+π+ decays is performed ...
Endovascular therapy of symptomatic high-grade stenosis of left internal carotid artery in C6 segment using Elutax “3” Neuro pDEB
2021
Measurement of beauty and charm production in pp collisions at √s = 5.02 TeV via non-prompt and prompt D mesons
2021
The pT-differential production cross sections of prompt and non-prompt (produced in beauty-hadron decays) D mesons were measured by the ALICE experiment at midrapidity (|y|< 0.5) in proton-proton collisions at √s = 5.02 TeV. The data sample used in the analysis corresponds to an integrated luminosity of (19.3 ± 0.4) nb−1. D mesons were reconstructed from their decays D0→ K−π+, D+→ K−π+π+, and Ds+→ϕπ+→K−K+π+ and their charge conjugates. Compared to previous measurements in the same rapidity region, the cross sections of prompt D+ and Ds+ mesons have an extended pT coverage and total uncertainties reduced by a factor ranging from 1.05 to 1.6, depending on pT, allowing for a more precise deter…
One Does Not Fit All: European Study Shows Significant Differences in Value-Priorities in Clean Sport
2021
Doping violates the Spirit of Sport and is thought to contradict the values which underpin this spirit. Values-based education (VBE) has been cited as a key element for creating a clean sport culture across age groups. Culturally relevant VBE requires understanding of the values that motivate athletes from different countries to practice their sport and uphold clean sport values. WADA's new International Standards for Education makes this study both needed and timely. Overall, 1,225 athletes from Germany, Greece, Italy, Russia, and the UK responded to measures assessing their general values, Spirit of Sport values, and their perceived importance of "clean sport". MaxDiff analysis identified…