showing 36 of ~574560 from 574555 documents
Performance Analysis of a Prototype High‐Concentration Photovoltaic System Coupled to Silica Optical Fibers
2021
High-concentration photovoltaic (HCPV) systems are one of the most promising technologies for the generation of renewable energy with high-conversion efficiency. Their development is still at an early stage, but the possibility of integrating high-concentration systems into buildings offers new opportunities to achieve the net-zero-energy building goal. Herein, the optical and energetic performance of a hybrid daylighting−HCPV prototype based on pure- or doped-silica optical fibers (OFs) to guide 2000× concentrated sunlight inside the buildings is evaluated. There, the light can either be used to illuminate interior spaces or projected on solar cells to generate electricity. The system equi…
Physical Activity and Accomplishment of Recommendations in University Students with Disabilities: A Longitudinal Study
2021
University settings are socio-environmental contexts that can reduce health disparities in students with disabilities. Therefore, the aim of this study was twofold: (a) to examine the longitudinal physical activity (PA) changes of Spanish university students with disabilities during a three-year period
Extracellular heat shock proteins in cancer: From early diagnosis to new therapeutic approach
2021
In cancer, human cells lose the ability to properly control the series of events that occur constantly during cell growth and division, including protein expression, stability, and dynamics. Heat shock proteins (Hsps) are key molecules in these events, constitutively expressed at high levels and could furthermore be induced by the response to cancer-induced stress. In tumor cells, Hsps have been shown to be implicated in the regulation of apoptosis, immune responses, angiogenesis and metastasis; in some cases, they can be overexpressed and dysregulated, representing important cancer hallmarks. In the past few years, it has been demonstrated that Hsps can be released by tumor cells through s…
Analysis of Pollutant Emissions on City Arteries—Aspects of Transport Management
2021
The aim of the study is to present a methodology for analyzing pollution emissions in a medium-sized city using modern traffic simulations in the aspect of minimizing exhaust emissions. The scope of the research and the methods of analysis used differ from those applied in big cities projects that can be found in the literature, Therefore the progressive elaboration model has been applied methodically to formulate and carry out the feasibility study. To perform microscopic traffic simulations, the software Simulation of Urban Mobility (SUMO—German Aerospace Center (DLR), Berlin, Germany) was applied. Thanks to the simulations, changes in traffic organization were accurately identified in th…
SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes
2021
Abstract Splicing is catalyzed by the spliceosome, a compositionally dynamic complex assembled stepwise on pre-mRNA. We reveal links between splicing machinery components and the intrinsically disordered ciliopathy protein SANS. Pathogenic mutations in SANS/USH1G lead to Usher syndrome—the most common cause of deaf-blindness. Previously, SANS was shown to function only in the cytosol and primary cilia. Here, we have uncovered molecular links between SANS and pre-mRNA splicing catalyzed by the spliceosome in the nucleus. We show that SANS is found in Cajal bodies and nuclear speckles, where it interacts with components of spliceosomal sub-complexes such as SF3B1 and the large splicing cofact…
Neutrophil extracellular traps arm DC vaccination against NPM-mutant myeloproliferation
2021
AbstractNeutrophil extracellular traps (NET) are web-like chromatin structures composed by dsDNA and histones, decorated with anti-microbial proteins. Their interaction with dendritic cells (DC) allows DC activation and maturation toward presentation of NET-associated antigens. Differently from other types of cell death that imply protein denaturation, NETosis preserves the proteins localized onto the DNA threads for proper enzymatic activity and conformational status, including immunogenic epitopes. Besides neutrophils, leukemic cells can release extracellular traps displaying leukemia-associated antigens, prototypically mutant nucleophosmin (NPMc+) that upon mutation translocates from nuc…
Dry Processing and Recycling of Thick Nacre–Mimetic Nanocomposites
2021
La notion de baroque dans le théâtre de Louis Calaferte
2021
International audience; Réédition légèrement remaniée de l’article de 2014 pour la réédition du théâtre complet de Calaferte
false
2021
The aim of this study was to provide information on energy availability (EA), macronutrient intake, nutritional periodization practices, and nutrition knowledge in young female cross-country skiers. A total of 19 skiers filled in weighted food and training logs before and during a training camp. Nutrition knowledge was assessed via a validated questionnaire. EA was optimal in 11% of athletes at home (mean 33.7 ± 9.6 kcal·kgFFM−1·d−1) and in 42% at camp (mean 40.3 ± 17.3 kcal·kgFFM−1·d−1). Most athletes (74%) failed to meet recommendations for carbohydrate intake at home (mean 5.0 ± 1.2 g·kg−1·d−1) and 63% failed to do so at camp (mean 7.1 ± 1.6 g·kg−1·d−1). The lower threshold of the pre-ex…
Notulae to the Italian alien vascular flora: 11
2021
Publisher Copyright: © This dataset is made available under the Open Database License (http://opendatacommons.org/licenses/odbl/1.0/). The Open Database License (ODbL) is a license agreement intended to allow users to freely share, modify, and use this Dataset while maintaining this same freedom for others, provided that the original source and author(s) are credited In this contribution, new data concerning the distribution of vascular flora alien to Italy are presented. It includes new records, confirmations, exclusions, and status changes for Italy or for Italian administrative regions. Nomenclatural and distribution updates published elsewhere are provided as Suppl. material 1. Peer rev…
Structure and dynamics of RNA guanine quadruplexes in SARS-CoV-2 genome. Original strategies against emerging viruses
2021
Guanine quadruplexes (G4) structures in viral genome have a key role in modulating viruses’ biological activity. While several DNA G4 structures have been experimentally resolved, RNA G4s are definitely less explored. We report the first calculated G4 structure of the RG-1 RNA sequence of SARS-CoV-2 genome, obtained by using a multiscale approach combining quantum and classical molecular modelling and corroborated by the excellent agreement between the corresponding calculated and experimental circular dichroism spectra. We prove the stability of RG-1 G4 arrangement as well as its interaction with G4 ligands potentially inhibiting viral protein translation.
Contextual engagement in event visitors’ experience and satisfaction
2021
This paper aims to advance the understanding of the experience-satisfaction relationship and the impact of the event context on such a relationship. In particular, there is an interplay between fou...
European Politics of Food Origin. A Semiotic Analysis of Geographical Indications
2021
This chapter investigates the relationship between food products and origin places within the European Union food policies. In the 1990s, the EU established a Geographical Indication (GI) system, constituted of a set of food quality brands and a legal framework for food, wine and spirits. This system, defined as a sui generis model by insiders, entails a strong EU government participation in the typical food symbolic and material modelling. The sui generis model establishes a government monopoly on the place-based labels registration and institutes an atypical kind of intellectual property based on geographic marks. By proposing a semiotic approach toward the analysis of European Geographic…
Implicit Wiener Filtering for Speech Enhancement In Non-Stationary Noise
2021
Speech quality is degraded in the presence of background noise, which reduces the quality of experience (QoE) of the end-user and therefore motivates the usage of speech enhancement algorithms. A large number of approaches have been proposed in this context. However most of them have focused on the case where the noise is stationary, an assumption that seldom holds in practice. For instance, in mobile telephony, noise sources with a marked non-stationary spectral signature include vehicles, machines, and other speakers to name a few. On the other hand, the usage of frequency-domain information in existing algorithms for speech enhancement in non-stationary noise environments can be made mor…
Global data on earthworm abundance, biomass, diversity and corresponding environmental properties
2021
Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ec…
Matching research and practice: Prediction of individual patient progress and dropout risk for basic routine outcome monitoring.
2021
OBJECTIVE Despite evidence showing that systematic outcome monitoring can prevent treatment failure, the practical conditions that allow for implementation are seldom met in naturalistic psychological services. In the context of limited time and resources, session-by-session evaluation is rare in most clinical settings. This study aimed to validate innovative prediction methods for individual treatment progress and dropout risk based on basic outcome monitoring. METHODS Routine data of a naturalistic psychotherapy outpatient sample were analyzed (N = 3902). Patients were treated with cognitive behavioral therapy with up to 95 sessions (M = 39.19, SD = 16.99) and assessment intervals of 5-15…
Mood, Burnout, and Dispositional Optimism in Kayak Polo Players During Their Competitive Stage.
2021
© 2021. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Accepted Manuscript version of a Published Work that appeared in final form in Frontiers in Psychology. To access the final edited and published work see 10.3389/fpsyg.2021.667603 The main objective of performance sport is to obtain achievements at the highest level through the adequate development of the athlete. The scientific literature demonstrates the fundamental role played by the inclusion of certain psychological variables in the training plan. This study examined the psychological profile of kayak polo players through the variables of burnou…
Exprimer ses émotions en ligne : l'exemple des commentaires sur Facebook
2021
International audience
Hot spots and gluon field fluctuations as causes of eccentricity in small systems
2021
We calculate eccentricities in high energy proton-nucleus collisions, by calculating correlation functions of the energy density field of the Glasma immediately after the collision event at proper time tau = 0. We separately consider the effects of color charge and geometrical hot spot fluctuations, analytically performing the averages over both in a dilute-dense limit. We show that geometric fluctuations of hot spots inside the proton are the dominant source of eccentricity whereas color charge fluctuations only give a negligible correction. The size and number of hot spots are the most important parameters characterizing the eccentricities.
Assembly Assistance System with Decision Trees and Ensemble Learning
2021
This paper presents different prediction methods based on decision tree and ensemble learning to suggest possible next assembly steps. The predictor is designed to be a component of a sensor-based assembly assistance system whose goal is to provide support via adaptive instructions, considering the assembly progress and, in the future, the estimation of user emotions during training. The assembly assistance station supports inexperienced manufacturing workers, but it can be useful in assisting experienced workers, too. The proposed predictors are evaluated on the data collected in experiments involving both trainees and manufacturing workers, as well as on a mixed dataset, and are compared …
Evolutionary rescue at different rates of environmental change is affected by trade-offs between short-term performance and long-term survival.
2021
As climate change accelerates and habitats free from anthropogenic impacts diminish, populations are forced to migrate or to adapt quickly. Evolutionary rescue (ER) is a phenomenon, in which a population is able to avoid extinction through adaptation. ER is considered to be more likely at slower rates of environmental change. However, the effects of correlated characters on evolutionary rescue are seldom explored yet correlated characters could play a major role in ER. We tested how evolutionary background in different fluctuating environments and the rate of environmental change affect the probability of ER by exposing populations of the bacteria Serratia marcescens to two different rates …
6BAF
2021
Słabości eksplanacyjne teorii inteligentnego projektu
2021
Artykuł powstrzymuje się od polemiki merytorycznej z teorią inteligentnego projektu, dalej TIP, a jedynie wskazuje na jej niedostatki metodologiczne. Dowodzi, że wbrew twierdzeniom jej zwolenników TIP nie jest falsyfikowalna. W odróżnieniu od teorii ewolucji nie może pełnić nawet roli metafizycznego programu badawczego w sensie Poppera. Co jednak ważniejsze, TIP nie pełni żadnych funkcji eksplanacyjnych. W grę wchodzą jedynie wyjaśnienia intencjonalne, TIP zaś nie jest w stanie zidentyfikować motywów domniemanego projektanta. Argument jest zilustrowany przykładami zaczerpniętymi od Stanisława Lema, które pokazują, że możliwych jest wiele alternatywnych hipotez na temat celów domniemanego pr…
Protein hydrolysates and mo-biofortification interactively modulate plant performance and quality of ‘canasta’ lettuce grown in a protected environme…
2021
Since the use of protein hydrolysates (PHs) enhances overall plant performance and quality of vegetables, they might be considered as a toll to face a number of concerns essentially associated to the growing request of premium quality foodstuff realized in agreement with eco-friendly agriculture practices. Molybdenum (Mo) is considered a fundamental trace element for human body. Thus, its shortage determines several disorders mainly related to neurological lesion and esophageal cancer. Biofortification of fruiting and leafy vegetables is a promising tool to prevent Mo deficiency in the human diet. The current study was carried out to assess the interactive effect of plant-derived PHs and Mo…
A Fatherland of Free Men. Virility and ‘Frailty’ in Spanish Liberalism (1808–1814)
2021
1400 years of man-environment interactions and soil evolution in the Saint-Mont mountain (Remiremont, Vosges)
2021
International audience; The SolHoM(a) project aims at determining the degree of landscape anthropisation in the Fossard massif (Remiremont, Vosges, France) by estimating the impact of past human occupations on current soils. Nowadays, a forest covers this relatively inhospitable mountain (hard climate, steep slopes, acid soils ...), but some remains suggest human presence for at least 1400 years.The Saint-Mont is a variscan orogenic granitic summit (height 672m) with valuable preserved archaeological relics, located south of the Fossard. At the top was founded the monasterium Habendum (from the 7th century to the French Revolution), which potentially comes after a late-antic castrum.Further…
<p><strong><em>Scutellospora deformata</em></strong><strong> (Scutellosporaceae), a new species of Gigasporales f…
2021
A new species S. deformata, that occurs in six locations of marine sand dunes along the eastern Mediterranean coast of Spain is described and illustrated from spores. In the field, the species occurred in the rhizosphere of Ammophila arenaria (Poaceae), Elymus farctus (Poaceae), Otanthus maritimus (Asteraceae), and Echinophora spinosa (Apiaceae). Morphological characters related with outer, middle and inner wall of the glomerospores as well as phylogenetic analysis (partial SSU, ITS1-5.8S region and the partial LSU nrDNA) support the hypothesis that the fungus is a new species of the Scutellosporaceae.
miRNAs and Genes Involved in the Interplay between Ocular Hypertension and Primary Open-Angle Glaucoma. Oxidative Stress, Inflammation, and Apoptosis…
2021
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2077-0383/10/11/2227 En esta investigación también participan: Mar Valero Vello, Silvia M. Sanz González, José E. O'Connor, David Galarreta Mira, María D. Pinazo-Durán y Vicente Zanón Moreno. Este artículo pertenece al número especial "Recent Clinical Research on Glaucoma". Glaucoma has no cure and is a sight-threatening neurodegenerative disease affecting more than 100 million people worldwide, with primary open angle glaucoma (POAG) being the most globally prevalent glaucoma clinical type. Regulation of gene expression and gene networks, and its multifactorial pathways involved in glaucoma disease are landmark…
Euripide, Ifigenia in Aulide
2021
This volume contains the first Italian critical edition with introduction, translation and commentary of Euripides’ Iphigenia in Aulis. The tragedy, exhibited posthumously in 405 BCE, stages the first mythical segment of the Trojan War, namely the sacrifice of Iphigenia, daughter of king Agamemnon, head of the Greek army, in order to propitiate the winds that should lead the navy to Troy. A tragedy of intrigue and unveiling, in which all the characters try to oppose the sacrifice, judged to be an impiety despite its sacred essence. It is therefore a tragedy without gods, in which characters of modest moral stature move, unstable, ready to sudden changes of mind, and among whom the protagoni…
A special Calabi–Yau degeneration with trivial monodromy
2021
A well-known theorem of Kulikov, Persson and Pinkham states that a degeneration of a family of K3-surfaces with trivial monodromy can be completed to a smooth family. We give a simple example that an analogous statement does not hold for Calabi–Yau threefolds.
You realise you are better when you want to live, want to go out, want to see people: Recovery as assemblage
2021
Background: The lack of social and material perspectives in descriptions of recovery processes is almost common in recovery research. Aim: Consequently, we investigated recovery stories and how people with mental health and/or addiction challenges included social and material aspects in these stories. Method: We conducted focus group and individual interviews. We investigated how the participants narrated their stories and how they assembled places and people in their recovery stories. Results: We found that narratives of recovery became assemblages where humans and their environments co-exist and are interdependent. Conclusion: As such, narratives about recovery are about everyday assembla…
Orthoptera Tettigoniidae as indicators of biodiversity hotspots in the Guinean Forests of Central and West Tropical Africa
2021
The present paper has two aims: 1) to present the results of the study of selected species of Orthoptera Tettigoniidae collected in the Guinean forests of West Africa and in the important hotspot of Dzanga-Ndoki National Park (Central African Republic); 2) to carry out a check-list of six subfamilies of Tettigoniidae (Pseudophyllinae, Conocephalinae, Hexacentrinae, Phaneropterinae, Mecopodinae and Hetrodinae) living in Central-West tropical Africa, in particular in two main tropical forests, in the subregion of upper Guinea, and in the subregion Nigeria-Cameroon plus the biodiversity hotspots of Central African Republic and Gabon. Many new records are reported and the following new species …
wild-type pas-gaf fragment from deinococcus radiodurans bphp
2021
Halbwachs lecteur de L’Éthique protestante, ou comment penser l’évolution des sociétés
2021
Maurice Halbwachs a ete un lecteur assidu de Max Weber dont il s’est efforce de faire connaitre l’œuvre au public francais, en publiant regulierement des comptes rendus de ses publications, au fur et a mesure de leurs parutions. Neanmoins, sa reception outrepasse cette simple presentation. Il a en effet entretenu un long dialogue avec la pensee de Weber sur la question de l’emergence et de l’evolution du capitalisme, laquelle croise certains de ses centres d’interets. La facon dont Halbwachs comprend et utilise le travail de Weber met en evidence un certain nombre de ses preoccupations dans des debats a l’interieur desquels s’inscrit sa reflexion dans les annees 1920-1930 : la memoire colle…
Learning and generalizing new nouns
2021
When they learn a new word, young children need to understand which are the relevant dimensions. The relevant dimensions are not always very salient, whereas salient properties might be conceptually irrelevant. This review illustrates the benefits of comparing simltaneously two (or more) examples introduced as members of the same category. This situation has been shown to be more effective for understanding the dimension relevance than the presentation of a single example or of several items introduced sequentially. We present studies showing that situations in which training examples are given are more effective than situations in which the examples are not labelled. We also include compar…
Isotope Shifts of Radium Monofluoride Molecules
2021
Isotope shifts of $^{223-226,228}$Ra$^{19}$F were measured for different vibrational levels in the electronic transition $A^{2}{}{\Pi}_{1/2}\leftarrow X^{2}{}{\Sigma}^{+}$. The observed isotope shifts demonstrate the particularly high sensitivity of radium monofluoride to nuclear size effects, offering a stringent test of models describing the electronic density within the radium nucleus. Ab initio quantum chemical calculations are in excellent agreement with experimental observations. These results highlight some of the unique opportunities that short-lived molecules could offer in nuclear structure and in fundamental symmetry studies.