Search results for " Integra"

showing 10 items of 2527 documents

A teacher's reflections on learning and teaching in an English-medium CLIL teaching experiment

2013

Tämän proseminaaritutkielman tarkoituksena oli tarkastella opiskelijoiden ja opettajan omaa suullista englanninkielen käyttöä englanniksi toteutetussa vieraskielisessä sisällönopetuksessa eli CLIL-opetuksessa työtään kehittävän ja ammatillista oppimista tavoittelevan tutkivan CLIL-opettajan näkökulmasta. CLIL-opetuskokeilu tapahtui Jyväskylän ammattikorkeakoulun musiikin koulutusohjelmassa lukuvuonna 2011–2012, ja oppisisältönä oli vapaan säestyksen opintojakso. Opetuskokeilun tavoitteena oli tukea osaltaan ammattikorkeakouluopiskelijoiden ammatillisen kielitaidon kehittymistä, erityisesti kykyä ymmärtää ja käyttää suullisessa kommunikaatiossa oman alan musiikillista sanastoa. Tutkimuksen t…

CLIL (Content and Language Integrated Learning) teachingteaching experiment
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Vēstures un angļu valodas integrēta apguve 9.klasē

2019

Globalizācija ir daļa no mūsu dzīves mūsdienas un tās nozīme tikai palielinās. Satura un valodas integrēta apguve ir plaši atzīta ne tikai Eiropā, bet arī visa pasaulē jau no 1990-tajiem gadiem. Satura un valodas integrēta apguve ir ļoti populāra, jo skolēniem arvien vairāk nepieciešama angļu valoda, lai turpinātu savas studijas. Viņiem niepieciešamas angļu valodas zināšanas akadēmiskā akademiskā līmeni, lai sekmīgi turpinātu studijas un saprast dažādus jēdzienus, ko lieto viņu izvēlētajā priekšmetā. Jēdzienus neapgūst angļu valodas stundās. Satura un valodas integrēta apguve nozīmē aktīvu starppriekšmetu saikni. Skolēni mācās angļu valodu ne tikai angļu valodas stundās, bet viņi izmanto an…

CLIL – Content and Language Integrate LearningPedagoģijaEnglish Language LearningCLIL AssessmentContent Knowledge
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Nessuno resta indietro: La Bellezza del Service Learning

2021

La chiusura delle scuole che ha provocato un incremento significativo della povertà educativa ha sollecitato l’opportunità di pro-gettare interventi integrati di service learning per favorire il recupero e il potenziamento dei minori in difficoltà. 869 studenti del Corso di Laurea Magistrale in Scienze della Formazione Primaria dell’Università degli Studi di Palermo, sono stati coinvolti nella progettazione e nella realizzazione di percorsi didattici mirati, rivolti agli alunni “fragili” di 33 scuole palermitane. Complessiva-mente sono state erogate 60.000 ore in DAD di attività di recupero e di potenziamento dell’apprendimento di alunni della scuola primaria di Palermo. Le attività didatti…

COVID-19 Service Learning inclusione integrazione responsabilità civica.COVID-19 Service Learning inclusion integration civic responsibility.Settore M-PED/03 - Didattica E Pedagogia Speciale
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Stronger proprioceptive BOLD-responses in the somatosensory cortices reflect worse sensorimotor function in adolescents with and without cerebral pal…

2020

Graphical abstract

CP-oireyhtymäCHILDRENSM1PASSIVE FINGERDP diplegic3124 Neurology and psychiatryEVOKED-POTENTIALSBRAINChildMOTOR CORTEXPassive movementTE echo timeEM expectation maximizationliikeaistiBOLD Blood-Oxygen-Level-Dependent signalRegular ArticleMagnetic Resonance ImagingTD typically-developedTR repetition timeSIIGMFCS Gross Motor Function Classification SystemMANCOVA Multivariate analysis of covarianceEPI echo planar imagingHP hemiplegicfMRI functional magnetic resonance imagingFemaleTACTILE STIMULATIONhalvausAGE-RELATED DIFFERENCESAdolescentComputer applications to medicine. Medical informaticsR858-859.7HemiplegiaORGANIZATIONDiplegiatuntoaistiMOVEMENTSIPT Sensory Integration and Praxis TestsROI regions of interestHumansSISII cortex secondary somatosensory cortexCP cerebral palsyRC346-429ComputingMethodologies_COMPUTERGRAPHICSGLM General Linear ModelCerebral Palsy3112 NeurosciencesSPM Statistical Parametric MappingSomatosensory CortexHandProprioceptionSI cortex primary somatosensory cortexGABA CONCENTRATIONKinesthesiaNeurology. Diseases of the nervous systemPSC percent signal change
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Preparing for CRIS: Challenges and Opportunities for Systems Integration at Finnish Universities

2014

Poster at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014 This paper raises issues presented by integrating administrative research information to institutional repository (IR) and other systems, especially in the context of Finnish universities. The observations are based on preparing for procurement of a Current Research Information System (CRIS) at the University of Jyväskylä. The CRIS will be used by various stakeholders in different organizational units, having conflicting requirements and different notions on system usage. For example, national reporting affects considerably the publication cataloging conventions. Determining the optimal data flow for handling publications,…

CRISinstitutional repositoriespublication reportingsystems integration
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filosofia e prassi di intervento in sede riabilitativa residenziale: l'esperienza della CTA "Lares" di Palermo

2007

CTA equipe interdisciplinare integrazione dei saperi progettualità riabilitativa
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MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L

2011

SummaryThe histone 3 lysine 79 (H3K79) methyltransferase Dot1l has been implicated in the development of leukemias bearing translocations of the Mixed Lineage Leukemia (MLL) gene. We identified the MLL-fusion targets in an MLL-AF9 leukemia model, and conducted epigenetic profiling for H3K79me2, H3K4me3, H3K27me3, and H3K36me3 in hematopoietic progenitor and leukemia stem cells (LSCs). We found abnormal profiles only for H3K79me2 on MLL-AF9 fusion target loci in LSCs. Inactivation of Dot1l led to downregulation of direct MLL-AF9 targets and an MLL translocation-associated gene expression signature, whereas global gene expression remained largely unaffected. Suppression of MLL translocation-a…

Cancer ResearchOncogene Proteins FusionCellular differentiationApoptosisBiologyMethylationArticleHistonesMice03 medical and health sciences0302 clinical medicinehemic and lymphatic diseasesmedicineAnimalsHumansEpigeneticsMyeloid Ecotropic Viral Integration Site 1 ProteinneoplasmsMyeloid Progenitor Cells030304 developmental biologyGene RearrangementHomeodomain Proteins0303 health sciencesLysineMyelodysplastic syndromesCell CycleCell DifferentiationCell BiologyHistone-Lysine N-MethyltransferaseMethyltransferasesMethylationDOT1Lmedicine.diseaseMolecular biologyHematopoiesisNeoplasm Proteins3. Good healthLeukemiaCell Transformation NeoplasticOncologyGenetic Loci030220 oncology & carcinogenesisHistone methyltransferaseCancer researchH3K4me3Protein Processing Post-TranslationalMyeloid-Lymphoid Leukemia ProteinCancer Cell
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Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort

2013

The work conducted at the WTCHG was supported by Wellcome Trust grants [076566/Z/05/Z] and [075491/Z/04]; the work in Zurich partly by an SNSF grant [32-108130]. We also thank MAF (Mutation Analysis core Facility) at the Karolinska Institute, Novum, Huddinge. The French part of the project was funded by Agence Nationale de la Recherche (ANR-06-NEURO-019-01 GENEDYS) and Ville de Paris. S Paracchini is a Royal Society University Research Fellow. D Czamara was supported by the Deutsche Forschungsgemeinschaft (German Research Foundation) within the framework of the Munich Cluster for Systems Neurology (EXC 1010 SyNergy). Dyslexia is one of the most common childhood disorders with a prevalence o…

Candidate geneDyslexia10064 Neuroscience Center Zurich10. No inequalityGenetics (clinical)ta515Geneticseducation.field_of_study10093 Institute of PsychologyR10058 Department of Child and Adolescent Psychiatry3. Good healthAssociation studyPhenotype10076 Center for Integrative Human PhysiologyWord-reading[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Reading disability2716 Genetics (clinical)GenotypePopulationLocus (genetics)610 Medicine & healthSpellingQH426 GeneticsBDYBiologyR Medicineta3111Polymorphism Single NucleotideArticleCandidate genesQuantitative Trait HeritableMeta-Analysis as Topic1311 GeneticsDCDC2mental disordersGeneticsmedicineHumanseducationQH426Genetic Association StudiesGenetic associationHaplotypeDyslexiamedicine.diseaseHaplotypesGenetic LociCase-Control Studies570 Life sciences; biology150 PsychologyGenome-Wide Association Study
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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

2010

We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the top association signals in 15,694 cases, 14,026 controls and 414 parent-offspring trios. We identified 30 new susceptibility loci meeting genome-wide significance (P < 5 x 10(-8)). A series of in silico analyses highlighted particular genes within these loci and, together with manual curation, implicated functionally interesting candidate genes including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2 and TAGAP. Combined with previously confirmed loci, these results identify 71 distinct loci with gen…

Candidate geneGenetic LinkagePROTEINGenome-wide association studyInflammatory bowel diseaseGenomeACTIVATION0302 clinical medicineCrohn DiseaseSEQUENCE VARIANTSGenetics0303 health sciencesGenomeNEDD4 FAMILYCOMMON VARIANTSASSOCIATION3. Good health030220 oncology & carcinogenesis10076 Center for Integrative Human PhysiologyComputational Biology; Crohn Disease; Genetic Linkage; Genetic Loci; Genetic Variation; Genome Human; Humans; Reproducibility of Results; Genetic Predisposition to Disease; Genome-Wide Association Study; Geneticsinflammatory-bowel-disease sequence variants common variants nedd4 family association gene identification receptor protein activationHuman/dk/atira/pure/subjectarea/asjc/1300/1311Locus (genetics)610 Medicine & healthBiology03 medical and health sciences1311 GeneticsGenetic linkagemedicineGeneticsHumansGenetic Predisposition to Disease030304 developmental biologyGenetic associationIDENTIFICATIONRECEPTORComputational BiologyGenetic VariationReproducibility of Resultsmedicine.diseaseGENESettore MED/03 - Genetica Medica10199 Clinic for Clinical Pharmacology and ToxicologyGenetic Loci570 Life sciences; biologyHuman genomegenome-wide scan.meta-analysis.crohn's diseaseGenome-Wide Association StudyINFLAMMATORY-BOWEL-DISEASE
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Quantum Effects and Phase Transitions in Adsorbed Molecular Layers

1998

Phase transitions in adsorbed (two dimensional) fluids and in adsorbed layers of molecules are studied with a combination of path integral Monte Carlo (PIMC), Gibbs ensemble Monte Carlo (GEMC) and finite size scaling techniques. Entropy driven phase transitions in systems with purely repulsive interactions are analyzed as well phase diagrams of fluids with internal quantum states. Adsorbed layers of H 2 molecules at a full monolayer coverage in the \(\sqrt 3 \times \sqrt 3 \) structure have a higher transition temperature to the disordered phase compared to the system with the heavier D 2 molecules, this effect is analyzed by PIMC. Linear N 2 molecules adsorbed on graphite show a transition…

Canonical ensemblePhase transitionMaterials scienceMean field theoryTricritical pointQuantum mechanicsPhase (matter)MonolayerPhysics::Chemical PhysicsPath integral Monte CarloPhase diagram
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