Search results for "AGEs"
showing 10 items of 8832 documents
Comparison between Citral and Pompia Essential Oil Loaded in Phospholipid Vesicles for the Treatment of Skin and Mucosal Infections
2020
Citrus species extracts are well known sources of bio-functional compounds with health-promoting effects. In particular, essential oils are known for their antibacterial activity due to the high content of terpenes. In this work, the steam-distilled essential oil from the leaves of Citrus limon var. pompia was loaded in phospholipid vesicles. The physico-chemical characteristics of the essential oil loaded vesicles were compared with those of vesicles that were loaded with citral, which is one of the most abundant terpenes of Citrus essential oils. The biocompatibility of the vesicles was assessed in vitro in human keratinocytes. Furthermore, the antimicrobial activity of the vesicles was t…
Binding of RNA Aptamers to Membrane Lipid Rafts: Implications for Exosomal miRNAs Transfer from Cancer to Immune Cells
2020
Intraluminal vesicles (ILVs) are released into the extracellular space as exosomes after the fusion of multivesicular bodies (MVBs) with the plasma membrane. miRNAs are delivered to the raft-like region of MVB by RNA-binding proteins (RBPs). RNA loading into exosomes can be either through direct interaction between RNA and the raft-like region of the MVB membrane, or through interaction between an RBP&ndash
Liturgia śląskich kanoników regularnych w średniowieczu
2016
In Medieval Silesia there were two convents o f the Canons Regular: in Wrocław and in Żagań. Their mother-monastery was the abbey in Arrovaise (Flanders). As every order, the Canons Regular had theirs own liturgical customs, in this case borrowed from Arrovai.se. These customs were practised in Silesia at least until the second h alf o f the 14th century, when they started to resemble m ore and m ore the diocesans practices. This phenomenon was particularly noticeable in the 15th century. A t that time, on one hand, we deal with the introduction of the inner-convents reforms, which aimed to elaborate the new statutes. On the other, we also deal with the willingness to enhance the liturgy by…
Increasing concentration of polyunsaturated fatty acids in browning boreal lakes is driven by nuisance algaGonyostomum
2020
Elevated concentrations of dissolved organic carbon (DOC) promote browning of lakes, which alters the physicochemical properties of water and ecosystem functioning. However, browning‐induced changes in basal production of polyunsaturated fatty acids from the n‐3 and n‐6 families (n‐3 and n‐6 PUFA) in lakes are not fully understood. The concentrations of PUFA, which are micronutrients required to maintain growth and reproduction of consumers, have been suggested to either rise or decline in seston as a response to lake browning. Elevated DOC concentrations may also promote bacterial biomass and production and thus potentially increase the concentration of bacterial fatty acids (BAFA) in sest…
Apoptotic-like Leishmania exploit the host´s autophagy machinery to reduce T-cell-mediated parasite elimination
2015
Apoptosis is a well-defined cellular process in which a cell dies, characterized by cell shrinkage and DNA fragmentation. In parasites like Leishmania, the process of apoptosis-like cell death has been described. Moreover upon infection, the apoptotic-like population is essential for disease development, in part by silencing host phagocytes. Nevertheless, the exact mechanism of how apoptosis in unicellular organisms may support infectivity remains unclear. Therefore we investigated the fate of apoptotic-like Leishmania parasites in human host macrophages. Our data showed--in contrast to viable parasites--that apoptotic-like parasites enter an LC3(+), autophagy-like compartment. The compartm…
Évolution des précipitations extrêmes dans le bassin versant du Mono (Bénin-Togo) en contexte de variabilité / changement climatique.
2014
International audience; Dans le golfe de Guinée et dans le bassin du Mono, au Bénin-Togo, en particulier, la population est de plus enplus exposée aux événements de précipitations extrêmes ou à l’intensité de ces événements causant des inondations de plusen plus récurrentes dans un environnement où on assiste à une croissance démographique galopante. L’objectif de cetteétude est : 1) d’analyser l’évolution des précipitations extrêmes dans le bassin au cours de la période 1988-2010 à partir dedonnées pluviométriques krigées ; 2) d’effectuer une comparaison avec les simulations régionales à 50 km de résolutionproduites par les modèles MPI, ICT, SMH et METO dans le cadre du projet Européen ENS…
Low-weight carboxylic acids as potential risk factor of compost phytotoxicity
2009
Being intermediates of organic matter degradation, low-weight carboxylic acids (LWCA) can occur at phytotoxic concentrations on bioactive soils or in the processed organic material applied to soil. While toxicity potentials and mixture effects of LWCA are still poorly known, the potential phytotoxicity of the biomaterials is difficult to assess. In the study effective concentrations (EC) of formic, acetic and propionic acids at non adjusted pH were obtained in short-term germination assays (48 h for cress, Lepidium sativum, and 120 h for ryegrass Lolium multiflorum) and subchronic growth assays (21d). Based on the EC values, LWCA inhibited more strongly plant growth than seed germination. I…