Search results for "Bridge"
showing 10 items of 355 documents
β‐Ketocarbonsäureester mit trans ‐Enolisierung
1986
Durch die Einfuhrung von Mesitylsubstituenten gelingt es, offenkettige β-Ketocarbonsaureester 10/11 herzustellen, die bevorzugt in der E-Konfiguration 2 der Enolform vorliegen. Der Energiegewinn der intramolekularen Wasserstoffbrucke in der Z-Konfiguration 1 wird durch die sterische Energie kompensiert. Sterische und elektronische Effekte bewirken, das die Ketoformen 10/11 energetisch so hoch liegen, das sie im Gleichgewicht keine Rolle spielen. Auser den Substituenteneinflussen von R1, R2 und R3 werden die Solvensabhangigkeit und die basekatalysierte Einstellung der Gleichgewichte 1⇄2 untersucht. Die hohe Energiebarriere fur die E,Z-Isomerisierung gestattet die Reindarstellung und Lagerung…
Tuning of the electronic and photophysical properties of ladder-type quaterphenyl by selective methylene-bridge fluorination
2016
The photophysics (spectral positions, band shapes, fluorescence quantum yields and lifetimes) of a series of fluorinated ladder type quaterphenyls L4P and L4P-Fn (n = 2, 4, 6) depend strongly on the degree and position of fluorine, despite the fact that substitution is not performed in the rings but only in methylene-bridges. This is driven by subtle differences in the molecular orbitals (MOs) participating in the electronic transitions, and in the vibronic pattern of the S0 and S1 electronic states as revealed by (TD)DFT calculations. Solid state spectra for n = 0, 2, 4 are similar to those of solution due to small intermolecular interactions as revealed by combined X-ray and (TD)DFT analy…
mGluR2/3 agonist LY379268, by enhancing the production of GDNF, induces a time-related phosphorylation of RET receptor and intracellular signaling Er…
2011
In the present study we aimed to verify if the enhancement of glial cell line-derived neurotrophic factor (GDNF) production in mouse striatum following treatment with LY379268 may also induce in the nigrostriatal system a time-related activation of RET receptor and its specific intracellular signaling. For this purpose, we have investigated the effects of LY379268 treatment on RET phosphorylation at the Tyr1062 and on downstream signaling Erk1/2, Akt and PLCγ1 pathway activation. The results showed that treatment with LY379268 (3 mg/kg) induces a significant increase of GDNF levels and time-related RET and Erk1/2 phosphorylation in the striatum. These increases were detected at 24 h and 48 …
One-pot, direct incorporation of [11C]CO2 into carbamates.
2009
Why beat about the bush? An operationally simple and mild reaction based on the direct fixation of (11)CO(2) with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) has been developed for the synthesis of (11)C-labeled carbamates at 75 degrees C within 10 minutes in radiochemical yields above 70% (see scheme). This strategy should be immediately useful for the construction of new radiotracers for positron emission tomography and other applications.
An analysis of co‐operative agreements from a knowledge‐based perspective: an integrative conceptual framework
2002
The last decade has been witness to an unprecedented growth in the number of alliances between companies. This growing importance of interfirm co‐operation, together with its inherent complexity, have generated a progressive interest in the study of this phenomenon, which has materialised in a vast but fragmented literature concerning it. As a response to the demands which these conditions pose, we have endeavoured to develop a conceptual framework which, from a knowledge‐based and learning perspective, integrates an extensive series of contributions and concepts for the study of the processes of co‐operation between companies. As distinctive features, our conceptual framework proposal sets…
Place Marketing and Management: A Complex Adaptive Systems View. The Strategic Planning of the City of Avellino, Italy
2016
The objective of this work is to contribute to place management and marketing studies by looking at the territory, as a complex adaptive system aiming to reach a dynamic equilibrium—a steady state. According to this approach, the territorial system emerges as a result of its capacity, its social actors and governance, and the analysis, creation and maintenance of relationships—the dynamics—between the territory components, both tangible and intangible ones, and its many and varied stakeholders. These relational dynamics produce continuous and reciprocal adaptive behaviours among social actors who determine, influence, and adapt the vision of the territory. Through an interdisciplinary appro…
L'orizzonte mobile. Su Koselleck
2013
Discussione del libro di D. Fusaro sull'approccio storiografico di R. Koselleck in dialogo critico con la Cambridge School
Removal of failed crown and bridge
2011
Crown and bridge have life span of many years but they fail for a number of reasons. Over the years, many devices have been designed to remove crowns and bridges from abutment teeth. While the removal of temporary crowns and bridges is usually very straightforward, the removal of a definitive cast crown with unknown cement is more challenging. Removal is often by destructive means. There are a number of circumstances, however, in which conservative disassembly would aid the practitioner in completing restorative/endodontic procedures. There are different mechanisms available to remove a failed crown or bridge. But there is no information published about the classification of available syste…
A non-heme dinuclear iron(II) complex containing a single, unsupported hydroxo bridge.
2006
Complexation of the tetrapodal pentadentate NN4 ligand 2,6-C5H3N[CMe(CH2NH2)2]2 (I) with iron(II) perchlorate hydrate in methanol, in the presence of N-methylimidazole, produces a diferrous complex with a single, unsupported mu-OH ligand between two {(I)FeII} coordination modules.
Don Quijote en el manga: Traducción, transformación y adaptación en la cultura de masas
2017
During the 19th Century and with the first translations of Don Quixote to japanese, Cervantes’ work started to be part of the country’s mass culture. As a manifestation of this phenomenon, the manga absorbed the image of the knight-errant. This comic genre adapted it to its aesthetic criteria and merged it with its history and folklore. At the same time, the manga has been exported to Western world, where readers and artists are familiarized with its characteristical style. Hence, Don Quixote works together with the manga as a bidireccional bridge between Japan and Spain. Far from the novel, the universality of this classic will find its way into the drawing and will take as base the popula…