Search results for "Elder"
showing 10 items of 919 documents
Effectiveness of unstable mini-boards to improve balance in institutionalised elderly people diagnosed with backward disequilibrium syndrome. Randomi…
2018
TITLE. Effectiveness of unstable mini-boards to improve balance in institutionalised old people diagnosed by Backward Disequilibrium Syndrome. Randomised controlled trial. BACKGROUND AND OBJECTIVES. BDS is a postural disorder which implies a posterior shift of a person's centre of gravity regarding their base of support, which increases falling risks. This study aims to determine whether a specific protocol with the use of unstable mini-boards can improve balance and motion in institutionalised old people diagnosed with BDS. MATERIALS AND METHODS. Single-blinded, two-group, randomised controlled clinical trial. Patients were institutionalised adults, age between 68 and 97, diagnosed with Ba…
Goût, préférences et comportement alimentaire
2016
La population âgée se caractérise par une grande variabilité, que ce soit au niveau de la capacité à percevoir les saveurs et les arômes, des préférences alimentaires ou des attitudes vis-à-vis de l’alimentation. Cependant, nous avons montré que 88% des seniors jugeaient important d’avoir des aliments « savoureux, ayant un bon goût ». Nous avons également montré qu’améliorer la qualité sensorielle des aliments en fonction des recommandations des seniors eux-mêmes permettait d’augmenter les quantités consommées. Face à l’enjeu que représente la dénutrition chez les seniors, la recherche, les services de restauration et les industries agro-alimentaires se doivent de développer une offre alime…
Gastric Dilation due to a Neuroleptic Agent in an Elderly Patient: A Case Report
2014
Neuroleptics may cause side effects, some of which are little known. We describe here a case of gastric dilation related to treatment with a neuroleptic in an elderly man. To our knowledge, such a case has never been reported in the literature. A 76-year-old man, living in a nursing home, was hospitalized for general weakness and abdominal pain. He had dementia with behavioral disorders treated with cyamemazine, a sedative and anxiolytic neuroleptic. Given a clinical suspicion of intestinal occlusion, an abdominopelvic computerized tomography scan was performed before the patient was admitted to our hospital. This computerized tomography scan did not show intestinal occlusion and there was …
Design for social media engagement: Insights from elderly care assistance
2015
Abstract This paper explores an alternative view of design as an emergent process of engagement and learning, as opposed to the traditional view of systems design as a problem-solving tool. We focus on digitally enabled elderly support networks as an innovative approach to the design of elderly care assistance through social media. Our research project is conducted in the context of an Italian health-care institution and provides the empirical backdrop illustrating the ensemble artefact, the four design principles and the pragmatic outcomes of personalized elderly care interventions. These contributions add both practical and theoretical guidance and learning regarding social-media engageme…
A context-aware approach for long-term behavioural change detection and abnormality prediction in ambient assisted living
2015
This research aims to describe pattern recognition models for detecting behavioural and health-related changes in a patient who is monitored continuously in an assisted living environment. The early anticipation of anomalies can improve the rate of disease prevention. Here we present different learning techniques for predicting abnormalities and behavioural trends in various user contexts. In this paper we described a Hidden Markov Model based approach for detecting abnormalities in daily activities, a process of identifying irregularity in routine behaviours from statistical histories and an exponential smoothing technique to predict future changes in various vital signs. The outcomes of t…
Prognosis Impact of Diabetes in Elderly Women and Men with Non-ST Elevation Acute Coronary Syndrome
2021
Few studies have addressed to date the interaction between sex and diabetes mellitus (DM) in the prognosis of elderly patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). Our aim was to address the role of DM in the prognosis of non-selected elderly patients with NSTEACS according to sex. A retrospective analysis from 11 Spanish NSTEACS registries was conducted, including patients aged ≥70 years. The primary end point was one-year all-cause mortality. A total of 7211 patients were included, 2,770 (38.4%) were women, and 39.9% had DM. Compared with the men, the women were older (79.95 ± 5.75 vs. 78.45 ± 5.43 years, p <
Post-Infectious Myocardial Infarction: New Insights for Improved Screening
2019
Acute infection is suspected of involvement in the onset of acute myocardial infarction (MI). We aimed to assess the incidence, pathogenesis and prognosis of post-infectious MI. All consecutive patients hospitalized for an acute MI in coronary care units were prospectively included. Post-infectious MI was defined by a concurrent diagnosis of acute infection at admission. Type 1 MI (acute plaque disruption) or Type 2 MI (imbalance in oxygen supply/demand) were adjudicated according to the universal definition of MI. From the 4573 patients admitted for acute MI, 466 (10%) had a concurrent acute infection (median age 78 (66–85) y, 60% male), of whom 313 (67%) had a respiratory tract infection.…
A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people
2009
The T cell branch of the immune system has been extensively studied in the elderly and it is known that the elderly have impaired immune function, mainly due to the chronic antigenic load that ultimately causes shrinkage of the T cell repertoire and filling of the immunologic space with memory T cells. In the present paper, we describe the IgD(-)CD27(-) double-negative B cell population which (as we have recently described) is higher in the elderly. Most of these cells were IgG(+). Evaluation of the telomere length and expression of the ABCB1 transporter and anti-apoptotic molecule, Bcl2, shows that they have the markers of memory B cells. We also show that these cells do not act as antigen…
Trafficking phenotype and production of granzyme B by double negative B cells (IgG(+)IgD(-)CD27(-)) in the elderly.
2013
The impairment of humoral immune response in elderly humans has been extensively demonstrated. We have reported the increase of memory B cells (IgG(+)IgD(-)CD27(-), double negative, DN) population in the elderly, in which there is also a typical inflammatory micro-environment. In order to evaluate whether this pro-inflammatory status could influence the trafficking phenotype of naïve/memory B cells, we have assessed the expression of CCR7, CCR6, CXCR3, CXCR4, CXCR5 and CD62L on naïve/memory B cell subpopulations in young and elderly subjects. Moreover, the combination of pro-inflammatory interleukin-21 (IL-21) and B cell receptor (BCR) stimulation enables B cells to produce and secrete gran…
B cell immunosenescence: different features of naive and memory B cells in elderly.
2011
Elderly people show a reduced protection against new infections and a decreased response to vaccines as a consequence of impairment of both cellular and humoral immunity. In this paper we have studied memory/naive B cells in the elderly, evaluating surface immunoglobulin expression, production of the pro- and anti-inflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-10, and presence of somatic hypermutation, focusing on the IgG(+)IgD(-)CD27(-) double negative (DN) B cells that are expanded in the elderly. Our results show that naive B cells from young donors need a sufficiently strong stimulus to be activated "in vitro", while naive B cells from old subjects are able t…