Search results for "Evidence"
showing 10 items of 1050 documents
Pharmacological properties of physical exercise in the elderly.
2013
Scientific evidence links physical activity to several benefits. Recently, we proposed the idea that exercise can be regarded as a drug. As with many drugs, dosage is of great importance. However, to issue a public recommendation of physical activity in aging is not an easy task. Exercise in the elderly needs to be carefully tailored and individualized with the specific objectives of the person or group in mind. The beneficial effects of exercise in two of the main age-related diseases, sarcopenia and Alzheimer's Disease, are dealt with at the beginning of this report. Subsequently, dosage of exercise and the molecular signaling pathways involved in its adaptations are discussed. Exercise a…
Evidence on the effectiveness of occupational health interventions.
2006
Background At present there exists no overview of the range of evidence currently available regarding the effectiveness of occupational health interventions (OHI). Methods Articles published in 2000 and 2001 in 16 general and specialized biomedical journals were searched for evaluations of OHI studies. Results Out of 8,687 articles searched there were 148 OHI studies. In 21% of the studies the study design was a randomized controlled trial, in 28% it was a controlled trial, an interrupted time-series in 7% and a different design in 44%. The occupational health outcomewasexposurein27%ofthestudies,workerbehaviorin12%,diseasesymptomsin 30%, disability or sickness absence in 24%, injuries in 4%…
Adaptación y estudio de las propiedades psicométricas del Cuestionario de consecuencias de consumo de alcohol en jóvenes, forma breve, en muestra esp…
2020
El objetivo de este trabajo es presentar la adaptación y estudio de las propiedades psicométricas del Cuestionario de consecuencias de consumo de alcohol en jóvenes, forma breve (B-YAACQ) en una muestra de 323 estudiantes de Psicología españoles, de los cuales el 74.3% son mujeres. Se realizó una retro-traducción de los ítems siguiendo las normas de la ITC, y un análisis factorial confirmatorio (AFC) con el programa Mplus mediante el método de extracción WLSMV y la matriz de correlaciones policóricas. El AFC arrojó resultados satisfactorios sobre el modelo unidimensional, con muy buenos indicadores de ajuste. Todas las saturaciones factoriales presentaron valores adecuados y fueron estadíst…
Creating Franchised Businesses Through Franchisee Training Program — Empirical Evidence from a Follow-up Study
2007
The Finnish franchisee training program was a unique training program since it was government financed and provided to prospective franchisees by a third party. The organizing parties were the Finnish Employment and Economic Development Centres and a private consultation company specialized in franchising. The training program aimed to find people interested in becoming franchisees and to give them the essential skills and knowledge a franchisee needs.
Corticosteroid-free immunosuppression in liver transplantation: a meta-analysis and meta-regression of outcomes.
2009
To examine the impact of steroid withdrawal from the immunosuppression protocols in liver transplantation. The electronic databases Medline, Embase, Pubmed and the Cochrane Library were searched. Meta-analysis pooled the effects of outcomes of a total of 2590 patients enrolled into 21 randomized controlled trials (RCTs), using classic and modern meta-analytic methods. Meta-analysis of RCTs addressing patients transplanted for any indication showed no differences between corticosteroid-free immunosuppression and steroid-based protocols in most of the analyzed outcomes. More importantly, steroid-free cohorts appeared to benefit in terms of de novo diabetes mellitus development [R.R = 1.86 (1.…
Abnormal Stock Market Returns Around Peaks in VIX: The Evidence of Investor Overreaction?
2016
Even though the VIX index was intended to be a measure of future volatility of the stock market, researchers argue that in reality VIX measures the investor sentiment. Anecdotal evidence suggests that peaks in VIX coincide with stock market bottoms followed by rallies, yet so far there have been no scientific evidence confirming this casual observation. In this paper we perform an event study of abnormal stock market returns around peaks in VIX and discuss our findings within the framework of behavioral finance theory. First of all, we detect peaks in VIX using formal turning-point identification procedures and provide detailed descriptive statistics of periods of rising and falling VIX. Th…
Positionspapier: Diagnostik und Therapie der Xerosis cutis.
2018
Hintergrund und rationale Die Xerosis cutis (Synonym: Xerodermie, trockene Haut, hydrolipidarme Haut) ist mit > 10 Millionen Betroffenen nicht nur eine der haufigsten dermatologischen Diagnosen in Deutschland, sondern auch Leitsymptom vieler dermatologischer, internistischer und neurologischer Erkrankungen. Trotz der medizinischen Relevanz der topischen Basistherapie fur die Xerosis cutis gibt es in Deutschland fur ihr Management bisher keinen wissenschaftlich belegten Diagnostik- und Therapiealgorithmus. ZIEL: Dieses Positionspapier vermittelt Arzten fachubergreifend einen an individuellen Symptomen orientierten, praxisnahen Leitfaden fur die Pravention, Diagnostik und Therapie der Xerosis…
Evidence-Based Assessment (EBA) in Psychiatrie, Klinischer Psychologie und Psychotherapie
2018
Zusammenfassung. In der klinischen Praxis gewinnen evidenzbasierte Behandlungsleitlinien zunehmend an Bedeutung. Innerhalb dieser finden sich jedoch nur unbefriedigende Informationen zur Diagnostik, speziell im Hinblick auf eine therapie-begleitende Diagnostik. Der Erfolg einer Therapie, ob Psycho- und/oder Pharmakotherapie, hängt jedoch von der Verzahnung von Therapie und Diagnostik ab, um z.B. den Therapieverlauf und -erfolg zu bewerten und bei Bedarf die therapeutische Strategie zu ändern. Der Ansatz des Evidence-Based Assessment (EBA) bietet hier ein hilfreiches Rahmenmodell und konkrete Vorschläge sowie Kriterien zur Realisierung dieser Verzahnung. Im Beitrag soll EBA vorgestellt sowi…
¿Es real el riesgo de osteoporosis y riesgo de fracturas con el uso crónico de inhibidores de la bomba de protones?
2011
Proton pump inhibitors (PPI) are one of the most widely used groups of drugs and their potential toxicity is periodically reviewed, emphasizing aspects originally considered secondary. The present review analyzes the physiological and pharmacological bases and the scarce clinical evidence for a potential association between the continued administration of PPI and the development of osteoporosis and bone fractures. Both disorders are clearly related to calcium homeostasis and are highly important in elderly patients due to their poor general prognosis and disabling consequences.
[Evidence-based emergency medicine].
1999
„Evidence Based Emergency Medicine” (EBEM) ist ein Begriff, der im Zusammenhang mit Qualitatsmanagement immer haufiger verwendet wird. Er soll letztlich zum Ausdruck bringen, das Effektivitat und Effizienz von Methoden, Verfahren, Medikationen etc. – wo immer moglich – durch wissenschaftliche Beweise (erhoben in kontrollierten Studien oder abgeleitet aus Metaanalysen, aber auch beruhend auf „State of the Art Reviews”) belegt werden mussen, bevor sie in die arztliche Praxis umgesetzt werden.Wo dies nicht oder nicht mehr moglich ist, mus versucht werden, die zugrundeliegenden diagnostischen und therapeutischen Prinzipien im Nachhinein zu validieren. Nur so kann die Lucke zwischen Forschung ei…