Search results for "Lipids"

showing 10 items of 2228 documents

O-Alkylation of a lignite humic acid by phase-transfer catalysis

2006

A mild phase-transfer catalytic reaction has been conducted to O-alkylate the acidic functions of a lignite humic acid (HA), using tetrabutylammonium hydroxide as the phase-transfer catalyst. The HA acidic functional groups were made to react, in tetrahydrofuran, by nucleophilic substitution with several alkyl halides-methyl iodide, and ethyl, propyl, and butyl, and benzyl bromide. The occurrence of the O-alkylation reaction was assessed by elemental analysis and 1H NMR, CPMAS 13C NMR, and FTIR spectroscopy. Bonding of alkyl groups increased the carbon and hydrogen content and the H/C ratios of all the humic reaction products. Increased nitrogen in the reaction products suggested incomplete…

chemistry.chemical_classificationSettore AGR/13 - Chimica AgrariaEtherAlkylationCarbon-13 NMRBiochemistryAnalytical ChemistryCatalysischemistry.chemical_compoundchemistryProton NMRNucleophilic substitutionHumic acidOrganic chemistrylipids (amino acids peptides and proteins)Humic substances O-Alkylation Phase-transfer catalysis Tetrabutylammonium hydroxide NMR FTIRAlkylAnalytical and Bioanalytical Chemistry
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Stereoselective Synthesis of β-1-O-Acyl Derivatives of Carbohydrates: An Application of the Cesium Effect.

1992

Abstract The stereoselective formation of anomerically pure 1-O-acyl derivatives of protected carbohydrates is achieved by reaction of the α-glycosyl halogenoses with cesium caboxylates.

chemistry.chemical_classificationStereochemistryOrganic Chemistrychemistry.chemical_elementBiochemistryAcylationchemistry.chemical_compoundAldosechemistryCaesiumDrug DiscoverySN2 reactionOrganic chemistrylipids (amino acids peptides and proteins)StereoselectivityCarboxylateTetrahedron Letters
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ChemInform Abstract: Glycoside Synthesis via Electrophile-Induced Activation of N-Allyl Carbamates.

2010

Abstract O-Benzyl-, O-acyl-, N-acyl- and isopropylidene-protected glycosyl N-allylcarbamates, obtained from anomerically unprotected monosaccharides and allyl isocyanate, are activated by an electrophile-induced cyclisation and react with hydroxyl compounds to form the corresponding glycosides.

chemistry.chemical_classificationStereochemistryorganic chemicalsGlycosideGeneral MedicineGlycoside synthesischemistry.chemical_compoundchemistryElectrophileMonosaccharideOrganic chemistrylipids (amino acids peptides and proteins)GlycosylAllyl isocyanateChemInform
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Regulatory activity of polyunsaturated fatty acids in T-cell signaling.

2009

n-3 Polyunsaturated fatty acids (PUFA) are considered to be authentic immunosuppressors and appear to exert beneficial effects with respect to certain immune-mediated diseases. In addition to promoting T-helper 1 (Th1) cell to T-helper 2 (Th2) cell effector T-cell differentiation, n-3 PUFA may also exert anti-inflammatory actions by inducing apoptosis in Th1 cells. With respect to mechanisms of action, effects range from the modulation of membrane receptors to gene transcription via perturbation of a number of second messenger cascades. In this review, the putative targets of anti-inflammatory n-3 PUFA, activated during early and late events of T-cell activation will be discussed. Studies h…

chemistry.chemical_classificationT-LymphocytesApoptosisCell BiologyT-Lymphocytes Helper-InducerBiologyBiochemistryArticleCell biologychemistryBiochemistrySecond messenger systemFatty Acids Unsaturatedlipids (amino acids peptides and proteins)Calcium SignalingSignal transductionProtein kinase AExtracellular Signal-Regulated MAP KinasesLipid raftProtein kinase CProtein Kinase CPolyunsaturated fatty acidDiacylglycerol kinaseCalcium signalingSignal TransductionProgress in lipid research
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ChemInform Abstract: Microwave-Assisted Tandem Organocatalytic Peptide-Coupling Intramolecular aza-Michael Reaction: α,β-Unsaturated N-Acyl Pyrazoles…

2015

Conjugated N-acyl pyrazoles are successfully employed in the organocatalytic enantioselective intramolecular aza-Michael reaction as ester surrogates.

chemistry.chemical_classificationTandemeducationEnantioselective synthesisPeptideGeneral MedicineConjugated systembehavioral disciplines and activitiesCombinatorial chemistryhumanitiesCoupling (electronics)chemistryOrganocatalysisIntramolecular forceMichael reactionlipids (amino acids peptides and proteins)ChemInform
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Heat capacities of butanol and pentanol in aqueous dodecyltrimethylammonium bromide solutions

1987

Heat capacities of the ternary systems water-dodecyltrimethylammonium bromide (DTAB)-butanol and water-DTAB-pentanol were measured at 25°C. The standard partial molar heat capacities of pentanol in micellar solutions show a maximum at about 0.35 mol-kg−1 DTAB that has been attributed to a micellar structural transition. This maximum tends to vanish by increasing the alcohol concentration and by decreasing the alcohol alkyl chain length; in the case of butanol it was not detected. The behavior of the standard partial molar heat capacities of alcohols in micellar solutions in the region above the cmc and below the structural transition was explained using a previously reported mass-action mod…

chemistry.chemical_classificationTernary numeral systemChemistryButanolInorganic chemistryDistribution constantBiophysicsThermodynamicsAlcoholBiochemistryMicelleHeat capacitychemistry.chemical_compoundMicellar solutionslipids (amino acids peptides and proteins)Physical and Theoretical ChemistryMolecular BiologyAlkylJournal of Solution Chemistry
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Quantitative separation of Trichoderma lipid classes on a bonded phase column.

1992

Bond Elut aminopropyl columns were used to purify the different lipid classes of Trichoderma harzianum and Trichoderma viride. This methodology permitted good separation of the fungal lipid classes in less time than traditional techniques. The incorporation of [1 (14)C]linoleic acid into neutral lipids, free fatty acids and phospholipids was quantified for both strains. The fatty acid profile of the different lipid classes of these fungal strains was determined as a function of culture time.

chemistry.chemical_classificationTrichodermaChromatographyChromatographybiologyChemistryLinoleic acidTrichoderma virideFatty AcidsTrichoderma harzianumFatty acidGeneral ChemistryFungi imperfectibiology.organism_classificationLipidschemistry.chemical_compoundColumn chromatographyLinoleic AcidsPhase (matter)Trichodermalipids (amino acids peptides and proteins)PhospholipidsJournal of chromatography
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Synthetic Glycopeptides of the Tandem Repeat Sequence of the Epithelial Mucin MUC4 with Tumour-associated Carbohydrate Antigens

2004

Glycohexadecapeptides representing the tandem repeat sequence of the epithelial mucin MUC4 were prepared by applying a solid-phase methodology. The required glycosyl amino acid building blocks containing the tumour-associated saccharide antigens T N -, T,- sialyl-T N , (2,6)- and (2,3)-sialyl-T were synthesized according to a straightforward biomimetic strategy by stepwise extension of the saccharide side chain of a Fmoc-protected galactosamine threonine tert-butyl ester.

chemistry.chemical_classificationTumor-Associated Carbohydrate AntigensChemistryOrganic ChemistryMucinGeneral MedicineMolecular biologyGlycopeptideAmino acidcarbohydrates (lipids)chemistry.chemical_compoundAntigenBiochemistryGalactosamineTandem Repeat SequenceSide chainGlycosylThreonineSynlett
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Unsaturated fatty acid bioavailability in growing rats fed low or adequate protein diets with sunflower or soybean oils

1993

Abstract The relationship of serum very low density lipoproteins (VLDL) to hepatic lipid composition was studied after 28 days of protein depletion to determine the interactions between dietary protein levels and the essential fatty acid (EFA) availability. This was examined in rats using a dietary combination of 20% or 2% casein with 5% vegetable oils, variable in their n-6:n-3 fatty acid ratios. Rats were divided into four groups, SFC (20% casein + 5% sunflower oil ); SFd (2% casein + 5% sunflower oil ); SC (20% casein + 5% soybean oil ); Sd (2% casein + 5% soybean oil ). Dietary protein depletion decreased phospholipid and protein concentrations in liver and VLDL, whereas triacylglycerol…

chemistry.chemical_classificationVery low-density lipoproteinNutrition and Dieteticsfood.ingredientLinolenic acidEndocrinology Diabetes and MetabolismLinoleic acidSunflower oilClinical BiochemistryFatty acidBiologyBiochemistrychemistry.chemical_compoundfoodchemistryEssential fatty acidBiochemistrylipids (amino acids peptides and proteins)Food scienceMolecular BiologyUnsaturated fatty acidPolyunsaturated fatty acidThe Journal of Nutritional Biochemistry
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On the problematic nature of vitamin E requirements: net vitamin E

1991

The requirement for vitamin E is closely related to the dietary intake of polyunsaturated fatty acids (PUFA). By the protective mechanism to prevent PUFA from being peroxidized, vitamin E is metabolically consumed. In addition, PUFA impair the intestinal absorption of vitamin E. Therefore PUFA generate an additional vitamin E requirement on the order of 0.6, 0.9, 1.2, 1.5, and 1.8 mg vitamin E (RRR-alpha-tocopherol-equivalents), respectively, for 1 g of dienoic, trienoic, tetraenoic, pentaenoic, and hexaenoic acid. For this reason, the gross vitamin E content of food containing PUFA does not allow an evaluation of this food as a source of vitamin E. A suitable measure is the net vitamin E c…

chemistry.chemical_classificationVitaminVitamin Emedicine.medical_treatmentDietary intakeNutritional Requirementsfood and beveragesMedicine (miscellaneous)Food composition dataMetabolismBiologyBiochemistryIntestinal absorptionchemistry.chemical_compoundDietary Fats UnsaturatedchemistryFatty Acids UnsaturatedmedicineHumansVitamin Elipids (amino acids peptides and proteins)Food scienceVitamin E deficiencyFood SciencePolyunsaturated fatty acidZeitschrift für Ernährungswissenschaft
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