Search results for "combinatorial"

A reusable polymer-supported copper(I) catalyst for triazole click reaction on water: An experimental and computational study

2019

Influence of Xantphos Derivative Ligands on the Coordination in Their Copper(I) and Silver(I) Complexes

2019

Easy Route to Functionalize Iron Oxide Nanoparticles via Long-Term Stable Thiol Groups

2009

International audience; The functionalization of superparamagnetic iron oxide nanoparticles (SPIOs) by meso-2,3-dimercaptosuccinic acid (DMSA) was investigated. Under ambient conditions, the thiol groups from DMSA are not stable and do not allow a direct functionalization without storage in stringent conditions or a chemical regeneration of free thiols. In this study, we have developed a protocol based on poly(ethylene glycol) (PEG) grafting of SPIO prior to DMSA anchoring. We have observed that PEG helps to increase the stability of thiol groups under ambient conditions. The thiol functionalized SPIOs were stable under physiological pH and ionic strength as determined by Ellman's essay and…

Selective encapsulation of a chloride anion in a 1H-pyrazole Cu2+ metallocage

2021

A self-assembled metallobox from copper(ii) and two macrocycles containing 1H-pyrazole ligands has been prepared. The internal cavity of the box is able to selectively encapsulate a single chloride anion over any other halide anion.

Ionic Liquids: Media for Better Molecular Catalysis

2004

Ionic liquids (ILs) are more and more suggested as substitutes for traditional solvents in organic synthesis and catalysis. They are suitable candidates for the dissolution of ionic complexes. They can activate and retain them in a polar state: in fact, they act as sequestrands, opening the route to two-phase processes and easier catalyst recovery. This paper reviews authors' results with the development of new syntheses of ILs and applications in carbon–carbon bond formation (dimerisation of methyl acrylate) and redistribution (ring closing metathesis) reactions using ionic precatalysts.

Do zwitterionic species exist in the non-enzymatic peptide bond formation?

2012

The use of proper computational methods and models has allowed answering the controversial question of whether zwitterionic species exist in the mechanism of peptide bond synthesis in aqueous solution. In fact, the different conformations of zwitterionic species open the door to different mechanistic paths.

Techniques for Biosynthesis

2015

Rapid and Complete Surface Modification with Strain-Promoted Oxidation-Controlled Cyclooctyne-1,2-Quinone Cycloaddition (SPOCQ)

2017

Abstract Strain‐promoted oxidation‐controlled cyclooctyne‐1,2‐quinone cycloaddition (SPOCQ) between functionalized bicyclo[6.1.0]non‐4‐yne (BCN) and surface‐bound quinones revealed an unprecedented 100 % conjugation efficiency. In addition, monitoring by direct analysis in real time mass spectrometry (DART‐MS) revealed the underlying kinetics and activation parameters of this immobilization process in dependence on its microenvironment.

Strain-Promoted Cycloaddition of Cyclopropenes with o-Quinones : A Rapid Click Reaction

2018

Abstract Novel click reactions are of continued interest in fields as diverse as bio‐conjugation, polymer science and surface chemistry. Qualification as a proper “click” reaction requires stringent criteria, including fast kinetics and high conversion, to be met. Herein, we report a novel strain‐promoted cycloaddition between cyclopropenes and o‐quinones in solution and on a surface. We demonstrate the “click character” of the reaction in solution and on surfaces for both monolayer and polymer brush functionalization.

ChemInform Abstract: Lanthanide Macrocyclic Complexes: From Molecules to Materials and from Materials to Devices.

2014

In the present review, we show how the chemistry of lanthanide macrocyclic complexes, which began almost 50 years ago in Russia, is still very active. Additionally to bisphthalocyanines complexes, triple-decker, but also quadruple- and quintuple-decker complexes have been synthesized via new chemical routes. The driving force for the development of this chemistry arises from the wide range of possible applications. Owing to their very high conductivity, compared to that of monophthalocyanines, LnPc2 and Ln2Pc3 complexes are used as molecular semiconductors in electronic devices. The radical nature of LnPc2 complexes makes them easily oxidized and reduced. This is the reason why they are par…