Search results for "libration"
showing 10 items of 901 documents
Determination of Amitriptyline with Bromocresol Purple and Flow Injection Analysis
1990
Abstract The study of some amitriptyline-dye systems was carried out in order to determine the best precipitate for the turbidimetric determination of amitriptyline using FIA. The reagent selected was bromocresol purple. The chemical and FIA variables were optimized. The calibration graph was linear over the concentration range 30.0–200.0 ppm of amitriptyline hydrochloride. Some interfering substances were also investigated.
FIA-fluorimetric determination of adrenaline by oxidation with a solid-phase reactor of manganese dioxide incorporated in polyester resin beads
1995
Abstract The FIA-spectrofluorimetric determination of adrenaline was carried out by reaction of the drug with manganese dioxide entrapped in a polymeric material in a solid-phase reactor; the oxidized drug was monitored fluorimetrically at 540 nm (Ioxg. 330.0 nm). The calibration graph for adrenaline was linear over the range 0.5 - 20 μg ml−1 with a relative standard deviation of 2.0% (at 5 ug ml−1) and the sample throughput of 65 h−1. The influence of foreign compounds was studied and the method was applied to the determination of adrenaline content in a pharmaceutical formulation . ∗Present address: Institut of Chemistry, Warsawa University, Bialystok Branch, Bialystok, Poland.
Determination of promethazine hydrochloride with bromophenol blue by a turbidimetric method and flow injection analysis
1992
Abstract A flow injection analysis procedure for the turbidimetric determination of promethazine is proposed. The sample solution is injected directly into the carrier reagent stream, which is composed of 1.16 × 10 −3 M bromophenol blue at pH 1.20. The calibration graph is linear over the range 25–197 ppm of promethazine. The influence of some foreign substances was also investigated. The method is applied to promethazine determination in a pharmaceutical formulation.
Cerium(IV) arsenite as a solid-phase reactor for use in flow-injection analysis. Spectrophotometric determination of promethazine
1992
Abstract Cerium(IV) arsenite is used as a strongly oxidizing solid-phase reactor in an unsegmented continuous-flow injection assembly. Its preparation procedure produces particles of uniform size with suitable physico-chemical properties for use in a continuous-flow system. A manifold is proposed for the determination of promethazine in pharmaceutical preparations by spectrophotometric monitoring of the red colour produced by the oxidized drug. A linear calibration graph is obtained over the range 5–400 μg ml −1 of promethazine.
Flow injection biamperometric determination of metronidazole with on-line photodegradation
1999
Abstract The determination of metronidazole is performed in a flow injection assembly, provided with a 40 W low pressure mercury lamp and a home-made biamperometric flow-cell furnished with two platinum electrodes polarized at 100 mV. The sample solution after being irradiated is inserted into a pure water stream. It then merges with an in situ mixed solution containing potassium iodide in sulphuric acid. The calibration graph was linear over the range 0.2–8.0 mg l −1 metronidazole; the 3 σ limit of detection was 0.008 mg l −1 ; the relative standard deviation was 0.6% (for 4 mg l −1 n = 13) and the sample throughput 50 h −1 . The influence of foreign compounds is slight and the method is …
Fourier transform infrared spectrometric strategies for the determination of Buprofezin in pesticide formulations
2002
Abstract Two different strategies for Buprofezin determination, an off-line extraction and stopped-flow determination and an automated procedure, based on the on-line extraction of Buprofezin samples with chloroform and flowing action analysis–fourier transform infrared (FIA–FT-IR) spectrometric measurement of the extracts, have been developed. For the treatment of the off-line extraction mode, data a three-factor partial least squares (PLSs) calibration was developed, using the region from 1465.7 to 1342.3 cm−1 with a single point baseline defined at 2051.9 cm−1 and based on the use of chloroform solutions of Buprofezin. The method provides a R.S.D. On the other hand, the recommended FIA m…
Direct flow injection chemiluminescence determination of salicylamide
1999
Abstract A new direct flow injection chemiluminescence method is proposed for the determination of salicylamide, based upon the oxidation of the drug by potassium permanganate in dilute sulphuric acid. The calibration graph is linear over the range 20 ng ml−1 (30 limit of detection)–8 μg ml−1 salicylamide, with a relative standard deviation (n=50, 0.5 μg ml−1) of 1.7%. The average sample insertion rate is 142 h−1. The influence of relevant foreign compounds is found to be relatively slight. The method is applied to the determination of salicylamide in a pharmaceutical formulation and human urine.
Determination of cyanide by a flow injection analysis-atomic absorption spectrometric method
1999
A new flow injection analysis (FIA) procedure is proposed for the indirect atomic absorption spectrometric determination of cyanide. The FIA manifold is based on the insertion of the sample into a distilled water carrier, then the sample flows through a solid-phase reactor filled with silver iodide entrapped in polymeric resin beads. The calibration graph is linear over the range 0.2-6.0 mg l-1 of cyanide (correlation coefficient 0.9974), the detection limit is 0.1 mg l-1, the sample throughput is 193 h-1 and the RSD is 0.8%. The method is simple, quick and more selective than other published FIA procedures. The reproducibility obtained by using different solid-phase reactors and solutions …
Flow injection spectrophotometric determination of lead using 1,5-diphenylthiocarbazone in aqueous micellar
2009
A simple flow injection colorimetric procedure for determining lead was established. It is based on the reaction of lead in sulfuric acid with 1,5-diphenylthiocarbazone and sodium dodecyl sulfate, resulting in an intense red-blue complex with a suitable absorption at 500 nm. A standard or sample solution was injected into the sulfuric acid stream (flow rate of 2.0 ml min(-1)), which was then merged with sodium dodecyl sulfate stream (flow rate of 2.0 ml min(-1)) and 1,5-diphenylthiocarbazone stream (flow rate of 1.5 ml min(-1)). Optimum conditions for determining lead were investigated by univariate method. Under the optimum conditions, a linear calibration graph was obtained over the range…
Determination of levamisole hydrochloride with HgI(2-)4 by a turbidimetric method and flow-injection analysis.
1986
Abstract This paper is concerned with the use of ion-association compounds in the analysis of pharmaceutical samples by FIA. The usual extraction into an organic phase is avoided by using turbidimetric detection. Determination of levamisole with HgI2−4 has been developed as a practical example: the experimental variables were optimized by the modified simplex method. The calibration graph is linear over the levamisole concentration range 7–32 μ g ml . The reproducibility (rsd) and injection sample rate are 0.9% and 80/hr, respectively.