Search results for "units"

showing 10 items of 576 documents

DEA-like Models for the Efficiency Evaluation of Hierarchically Structured Units

2004

Abstract The knowledge of the internal structure of decision making units (DMUs) gives further insights with respect to the “black box” perspective when considering data envelopment analysis models. We present one-level and two-level hierarchical structures of the DMUs under evaluation. Each unit is composed of consecutive stages of parallel subunits all with constant returns to scale. In particular, the maximization of the relative efficiency of a DMU is studied. For the two-stage situation, different degrees of coordination among the subunits of the hierarchical levels are discussed. When some form of coordination has to be guaranteed, we introduce balancing constraints and we compare two…

Mathematical optimizationInformation Systems and ManagementReturns to scaleGeneral Computer ScienceHierarchy (mathematics)Data envelopment analysis; Efficiency evaluation; Hierarchy; Structured unitsStructure (category theory)DATA ENVELOPMENT ANALYSISMaximizationManagement Science and Operations ResearchIndustrial and Manufacturing EngineeringEfficiency evaluationPerspective (geometry)EfficiencyHierarchyModeling and SimulationBlack boxData envelopment analysisDATA ENVELOPMENT ANALYSIS; Network DEA; Efficiency evaluationNetwork DEAMathematicsStructured units
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Anomalous water dynamics in brain: a combined diffusion magnetic resonance imaging and neutron scattering investigation

2019

International audience; Water diffusion is an optimal tool for investigating the architecture of brain tissue on which modern medical diagnostic imaging techniques rely. However, intrinsic tissue heterogeneity causes systematic deviations from pure free-water diffusion behaviour. To date, numerous theoretical and empirical approaches have been proposed to explain the non-Gaussian profile of this process. The aim of this work is to shed light on the physics piloting water diffusion in brain tissue at the micrometre-to-atomic scale. Combined diffusion magnetic resonance imaging and first pioneering neutron scattering experiments on bovine brain tissue have been performed in order to probe dif…

Medical diagnosticMaterials science[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/ImagingQuantitative Biology::Tissues and OrgansPhysics::Medical PhysicsBiomedical EngineeringBiophysicsproton dynamicsBioengineeringbrain imagingNeutron scatteringBiochemistryAtomic unitsBiomaterials03 medical and health sciences0302 clinical medicineTissue heterogeneityWater dynamicsNuclear magnetic resonancemedicineAnimalsDiffusion (business)030304 developmental biologydiffusion magnetic resonance imaging0303 health sciencesProton dynamicmedicine.diagnostic_testneutron scatteringBrainWaterMagnetic resonance imagingwater diffusionLife Sciences–Physics interfaceMagnetic Resonance ImagingSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Neutron Diffraction[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/ImagingBovine brainBrain imaging; Diffusion magnetic resonance imaging; Neutron scattering; Proton dynamics; Water diffusionCattle030217 neurology & neurosurgeryBiotechnology
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Monitoring temporal changes in the spatial patterns of a Mediterranean shrubland using Landsat TM images

2001

Summary The overall goal of this study is to understand the structure and function of a Mediterranean shrubland at landscape scale by means of satellite images and GIS. Specifically, to assess the sensitivity of several spatial statistics to characterise landscape pattern, measure fragmentation and quantify the change through time. We study the landscape structure of a Mediterranean shrubland located in the east part of Spain (Valencia) and the change in spatial patterns of different shrubs types from 1984 to 1994. To accomplish these objectives, we used 10 Landsat™ images from 1984 to 1994 (except 1988) to which a geometric correction and an atmospheric normalization was applied. In additi…

Mediterranean climategeographygeography.geographical_feature_categoryEcologyElevationVegetationRemote sensingShrublandSpatial patternsSpatial ecologyEnvironmental scienceLandscape unitsEnvironmental constantsScale (map)Digital elevation modelSpatial analysisEcology Evolution Behavior and Systematics
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Prevention of nosocomial infections and surveillance of emerging resistances in NICU

2011

Neonates hospitalized in NICU are at risk for healthcare associated infections because of their poor immune defenses, related to gestational age, colonization of mucous membranes and skin with nosocomial microorganisms, exposure to antibiotics, invasive procedures and frequent contacts with healthcare workers (HCWs). Healthcare associated infections are the major source of morbidity and mortality in NICU in the developed world. Most infections are caused by Gram-positive organisms, fulminant sepsis are often associated to Gram-negative organisms, fungal sepsis occurs frequently in ELBW infants. Hand hygiene is the most important preventive procedure, nevertheless hand hygiene compliance amo…

Methicillin-Resistant Staphylococcus aureusmedicine.medical_specialtymedicine.drug_classprevention surveillance nosocomial infections resistance neonate multidrug resistant organisms methicillin resistant staphylococcus aureusmedia_common.quotation_subjectAntibioticsDrug resistancemedicine.disease_causeCommunicable Diseases EmergingSepsisSettore MED/38 - Pediatria Generale E SpecialisticaHygieneIntensive Care Units NeonatalHumansMedicineIntensive care medicinemedia_commonCross InfectionInfection Controlbusiness.industryTransmission (medicine)Infant NewbornObstetrics and GynecologyDrug Resistance Microbialmedicine.diseaseAntimicrobialMethicillin-resistant Staphylococcus aureusDrug Resistance MultiplePopulation SurveillancePediatrics Perinatology and Child HealthbusinessFluconazolemedicine.drugThe Journal of Maternal-Fetal & Neonatal Medicine
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Characterization of Acinetobacter baumannii from intensive care units and home care patients in Palermo, Italy.

2011

AbstractIn this study 45 isolates of Acinetobacter baumannii identified from patients in intensive care units of three different hospitals and from pressure ulcers in home care patients in Palermo, Italy, during a 3-month period in 2010, were characterized. All isolates were resistant to at least three classes of antibiotics, but susceptible to colistin and tygecycline. Forty isolates were non-susceptible to carbapenems. Eighteen and two isolates, respectively, carried the blaOXA-23-like and the blaOXA-58-like genes. One strain carried the VIM-4 gene. Six major rep-PCR subtype clusters were defined, including isolates from different hospitals or home care patients. The sequence type/pulsed …

Microbiology (medical)Acinetobacter baumanniimedicine.medical_specialtyPediatricsSettore MED/07 - Microbiologia E Microbiologia ClinicaGenotypeDrug resistanceMicrobial Sensitivity Testshome care patientsintensive care unitbeta-Lactamaseslaw.inventionlawmultidrug resistanceIntensive careInternal medicineDrug Resistance Multiple BacterialGenotypepolycyclic compoundsmedicinePulsed-field gel electrophoresisCluster AnalysisHumansCross Infectionbiologybusiness.industryGeneral Medicinebiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationIntensive care unitHome Care ServicesAcinetobacter baumanniiAnti-Bacterial AgentsElectrophoresis Gel Pulsed-FieldCommunity-Acquired InfectionsMolecular TypingIntensive Care UnitsInfectious DiseasesItalyColistinMultilocus sequence typingepidemiologybusinesshome caremedicine.drugAcinetobacter InfectionsMultilocus Sequence Typing
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Performance of existing definitions and tests for the diagnosis of invasive aspergillosis in critically ill, non-neutropenic, adult patients: An upda…

2022

Microbiology (medical)AdultInvasive Pulmonary AspergillosisIntensive Care UnitsAspergillusInfectious DiseasesCOVID-19 TestingCritical IllnessAspergillosisCOVID-19HumansSettore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICAInvasive Fungal InfectionsThe Journal of infection
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Outbreak of multi-resistant Corynebacterium striatum infection in an Italian general intensive care unit.

2007

Microbiology (medical)AdultMaleSTRAINmedicine.medical_specialtyAdolescentNOSOCOMIAL PATHOGENCorynebacteriumlaw.inventionDisease OutbreakslawDrug Resistance Multiple BacterialRNA Ribosomal 16SmedicineHumansIntensive care medicineAgedAged 80 and overCross InfectionCorynebacterium Infectionsbusiness.industryNOSOCOMIAL PATHOGEN; STRAINOutbreakGeneral MedicineMiddle AgedIntensive care unitResistant tuberculosisCorynebacterium striatumIntensive Care UnitsInfectious DiseasesItalyFemalebusinessThe Journal of hospital infection
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Outbreak of infection with Klebsiella pneumoniae sequence type 258 producing Klebsiella pneumoniae Carbapenemase 3 in an intensive care unit in Italy

2010

Gram-negative pathogens producing carbapenemases represent an alarming clinical threat with serious effects on patient outcomes ([3][1], [7][2]). In 2001, Yigit et al. ([11][3]) reported a novel β-lactamase termed “ K lebsiella pneumoniae carbapenemase” (KPC-1) in North Carolina. KPC-producing

Microbiology (medical)AdultMaleSettore MED/07 - Microbiologia E Microbiologia ClinicaAdolescentGenotypeKlebsiella pneumoniaemedicine.medical_treatmentTreatment outcomeMicrobial Sensitivity TestsKlebsiella pneumoniae carbapenem UTI outbreakbeta-Lactamaseslaw.inventionDisease courseMicrobiologyDisease OutbreaksBacterial proteinBacterial Proteinslawpolycyclic compoundsMedicineHumansLetters to the EditorAgedAged 80 and overbiologybusiness.industryOutbreakKlebsiella infectionsSequence Analysis DNAMiddle Agedbacterial infections and mycosesbiology.organism_classificationIntensive care unitDNA FingerprintingAnti-Bacterial AgentsBacterial Typing TechniquesKlebsiella InfectionsIntensive Care UnitsKlebsiella pneumoniaeTreatment OutcomeItalyBeta-lactamaseFemalebusiness
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Containment of a Large SARS-CoV-2 Outbreak Among Healthcare Workers in a Pediatric Intensive Care Unit.

2020

Objective Healthcare workers (HCWs) are particularly exposed SARS-CoV-2 because they are critical in preventing viral transmission and treating COVID-19 patients. Within HCWs, personnel of intensive care units (ICUs) are at the forefront of treating patients with a severe course of COVID-19 infection and therefore represent an extremely vulnerable group. Thus, our objective is to contribute to establish means of infection control protecting HCWs in the frontline of the current pandemic. Design An outbreak of SARS-CoV-2 was detected and contained in a pediatric ICU (PICU). The first positive case was identified with a point-of-care diagnostic system on site. Real-time PCR-based testing syste…

Microbiology (medical)AdultMalemedicine.medical_specialtyInfectious Disease Transmission Patient-to-ProfessionalSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Health PersonnelPneumonia ViralPsychological interventionIntensive Care Units PediatricHospitals UniversityTertiary Care Centers03 medical and health sciencesBetacoronavirusYoung Adult0302 clinical medicine030225 pediatricsIntensive careGermanyPandemicHealth caremedicineInfection controlHumansPediatrics Perinatology and Child Health030212 general & internal medicinePandemicsPediatric intensive care unitInfection Controlbusiness.industrySARS-CoV-2virus diseasesOutbreakCOVID-19Middle AgedInfectious DiseasesPediatrics Perinatology and Child HealthEmergency medicineQuarantineFemalebusinessCoronavirus InfectionsThe Pediatric infectious disease journal
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Anidulafungin dosing in critically ill patients with continuous venovenous haemodiafiltration

2014

Background Anidulafungin is indicated as a first-line treatment for invasive candidiasis in critically ill patients. In the intensive care unit, sepsis is the main cause of acute renal failure, and treatment with continuous renal replacement therapy (CRRT) has increased in recent years. Antimicrobial pharmacokinetics is affected by CRRT, but few studies have addressed the optimal dosage for anidulafungin during CRRT. Patients and methods We included 12 critically ill patients who received continuous venovenous haemodiafiltration to treat acute renal failure. Anidulafungin was infused on 3 consecutive days, starting with a loading dose (200 mg) on Day 1, and doses of 100 mg on Days 2 and 3. …

Microbiology (medical)Antifungal AgentsCritical Illnessmedicine.medical_treatmentHemodiafiltrationAnidulafunginLoading doselaw.inventionSepsisEchinocandinsPharmacokineticslawmedicineHumansCandidiasis InvasivePharmacology (medical)Trough ConcentrationRenal replacement therapyDosingCandidaPharmacologybusiness.industrybacterial infections and mycosesmedicine.diseaseIntensive care unitIntensive Care UnitsInfectious DiseasesAnesthesiaAnidulafunginbusinessmedicine.drugJournal of Antimicrobial Chemotherapy
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