showing 36 of ~574560 from 574555 documents
El paisaje lingüístico de la migración en el barrio de Ruzafa (Valencia) : una mirada a través del tiempo
2021
Esta investigación estudia el paisaje lingüístico del barrio de Ruzafa en Valencia (España), conocido por su carácter multicultural y multilingüístico debido al establecimiento de población migrante en las últimas décadas del siglo XX y a su transformación en un espacio turístico como consecuencia del proceso de gentrificación en los primeros años del siglo XXI. El objetivo es explorar a través de los signos del paisaje lingüístico los cambios socio-demográficos desde un enfoque diacrónico y contrastivo. La metodología está basada en la utilización combinada de la herramienta Google Street View y con la toma de signos en los mismos espacios del barrio, con lo que se ha configurado un corpus…
Connecting others: Does a tertius iungens orientation shape the relationship between research networks and innovation?
2021
Research on social networks and innovation emphasizes that individuals spanning structural holes and crossing institutional boundaries have more opportunities for knowledge recombination and innovation involvement. However, transforming the potential knowledge and resources available through personal networks to attain innovation can be difficult for the focal individual. Using an ego-network approach, this study examines whether and to what extent an individual strategic orientation to cooperation (i.e. tertius iungens) contributes to strengthening the relation between two personal network properties (structural and institutional separation) and involvement in innovation. Our analysis is c…
Differences in Health Status, Health Behavior and Health Care Utilization between Immigrant and Native Homeless People in Spain: an Exploratory Study
2021
Few studies have examined the differences between immigrant and native‐born homeless populations. Our aim was to conduct an exploratory study to examine the differences in health status, health behaviour and healthcare utilisation in a sample of Spanish immigrant and native homeless people. Study was conducted in eight different temporary accommodations in the Valencia region in August 2018. Overall, 86 participants were included in the analysis who answered questionnaires concerning socio‐demographic characteristics, immigration status, health status and behaviour, healthcare utilisation and experienced discrimination in healthcare and health literacy. In total, 76.7% were men with a mean …
Cold Atmospheric Plasma Promotes Regeneration-Associated Cell Functions of Murine Cementoblasts In Vitro
2021
The aim of the study was to examine the efficacy of cold atmospheric plasma (CAP) on the mineralization and cell proliferation of murine dental cementoblasts. Cells were treated with CAP and enamel matrix derivates (EMD). Gene expression of alkaline phosphatase (ALP), bone gamma-carboxyglutamate protein (BGLAP), periostin (POSTN), osteopontin (OPN), osterix (OSX), collagen type I alpha 1 chain (COL1A1), dentin matrix acidic phosphoprotein (DMP)1, RUNX family transcription factor (RUNX)2, and marker of proliferation Ki-67 (KI67) was quantified by real-time PCR. Protein expression was analyzed by immunocytochemistry and ELISA. ALP activity was determined by ALP assay. Von Kossa and alizarin r…
The Assessment of Risk Factors for Long-term Survival Outcome in ypN0 Patients With Rectal Cancer After Neoadjuvant Therapy and Radical Anterior Rese…
2021
Abstract Background The main negative prognostic factors in patients with rectal cancer after radical treatment include regional lymph node involvement, lymphovascular invasion, and perineural invasion. However, some patients still develop cancer recurrence despite the absence of the above risk factors. The aim of the study was to assess clinicopathological factors influencing long-term oncologic outcomes in ypN0M0 rectal cancer patients after neoadjuvant therapy and radical anterior resection. Methods A retrospective survival analysis was performed on a group of 195 patients. We assessed clinicopathological factors which included tumor regression grade, number of lymph nodes in the specime…
Root vacuolar sequestration and suberization are prominent responses of Pistacia spp. rootstocks during salinity stress
2021
Abstract Understanding the mechanisms of stress tolerance in diverse species is needed to enhance crop performance under conditions such as high salinity. Plant roots, in particular in grafted agricultural crops, can function as a boundary against external stresses in order to maintain plant fitness. However, limited information exists for salinity stress responses of woody species and their rootstocks. Pistachio (Pistacia spp.) is a tree nut crop with relatively high salinity tolerance as well as high genetic heterogeneity. In this study, we used a microscopy‐based approach to investigate the cellular and structural responses to salinity stress in the roots of two pistachio rootstocks, Pis…
Multi-omics approaches to improve malaria therapy.
2021
Malaria contributes to the most widespread infectious diseases worldwide. Even though current drugs are commercially available, the ever-increasing drug resistance problem by malaria parasites poses new challenges in malaria therapy. Hence, searching for efficient therapeutic strategies is of high priority in malaria control. In recent years, multi-omics technologies have been extensively applied to provide a more holistic view of functional principles and dynamics of biological mechanisms. We briefly review multi-omics technologies and focus on recent malaria progress conducted with the help of various omics methods. Then, we present up-to-date advances for multi-omics approaches in malari…
Glukoseschwankungen und Distress im Alltag: Vergleich zwischen subjektivem Erleben und objektiven CGM-Parametern
2021
Ocean Circulation Model Applications for the Estuary-Coastal-Open Sea Continuum
2021
Coastal zones are among the most variable environments. As such, they require adaptive water management to ensure the balance of economic and social interests with environmental concerns. High quality marine data of hydrographic conditions e.g., sea level, temperature, salinity, and currents are needed to provide a sound foundation for the decision making process. Operational models with sufficiently high forecasting quality and resolution can be used for a further extension of the marine service toward the coastal-estuary areas. The Limfjord is a large and shallow water body in Northern Jutland, connecting the North Sea in the West and the Kattegat in the East. It is currently not covered …
Parte III, Capitolo III, Fondo e azienda agricola
2021
Questo volume nasce dalla necessità di offrire una lettura aggiornata, contemporanea appunto, delle peculiari regole che tradizionalmente han- no attribuito al Diritto agrario un carattere di specialità. Facciamo riferimento alle norme che in un’ottica di programmazione di un settore produttivo peculiare disciplinano l’impresa agricola, la proprietà terriera, i contratti agrari, il lavoro agricolo, il credito agrario, il mercato dei prodotti agricoli. Regole la cui chiave di lettura è sempre passata dalla considerazione dell’esistenza di un legame stretto tra “agricoltura” e “terra”, considerazione che non riteniamo superata, ma piuttosto aggiornata, dalle numerose innovazioni legislati…
Modeling and Mitigating Errors in Belief Propagation for Distributed Detection
2021
We study the behavior of the belief-propagation (BP) algorithm affected by erroneous data exchange in a wireless sensor network (WSN). The WSN conducts a distributed multidimensional hypothesis test over binary random variables. The joint statistical behavior of the sensor observations is modeled by a Markov random field whose parameters are used to build the BP messages exchanged between the sensing nodes. Through linearization of the BP message-update rule, we analyze the behavior of the resulting erroneous decision variables and derive closed-form relationships that describe the impact of stochastic errors on the performance of the BP algorithm. We then develop a decentralized distribute…
Comparison of Physical Activity and Sedentary Behaviour between Schoolchildren with Cystic Fibrosis and Healthy Controls: A Gender Analysis
2021
The purpose of this study was to examine differences in sports participation and the levels of physical activity (PA) and sedentary behaviour (SB) between schoolchildren with cystic fibrosis (CF) and a healthy control group (CG) taking into account the gender variable. PA and SB were measured with an accelerometer for 7 consecutive days in 44 children (24 girls
The Emergence and Restoration of the State: Latvia in 1918 and 1990
2021
Abstract On 18 November 1918, the independent Republic of Latvia was declared in an extremely complicated international and domestic environment—the First World War was still going on, empires were collapsing, and ethnically and ideologically diverse military troops were fighting within the boundaries of Latvian territory. Despite the historical context of a previously tense relationship between Latvians and other ethnic groups, representatives of all minorities fought next to Latvians against the enemies of the Latvian state. Up until 11 August 1920, when the Peace Treaty with the Soviet Russia was signed, the prospects of de jure recognition of the newly established state were blurred; ye…
Early Onset of Guillain–Barré Syndrome Following Lumbar Disc Herniation Surgery: An Unexpected Clinical Evolution
2021
Letter: Guillain–Barré syndrome (GBS), is a neurologic complication rarely reported following a spinal surgery procedure.1, 2, 3, 4, 5, 6 GBS is a potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. It is the most common cause of acute flaccid paralysis, with an annual global incidence of approximately 1–2 per 100,000 person-years.7 Although the clinical presentation of the disease is heterogeneous, patients typically present with weakness and sensory signs in the legs that progress to the arms and cranial muscles. Disease progression can be rapid in approximately 20% of patients with respiratory failure requiring mech…
Granelle locali alternative a mais e soia nella dieta dei ruminanti allevati in biologico
2021
Tra le granelle di leguminose, la fava, il favino, il pisello e il cece, per il loro contenuto in proteine possono sostituire anche integralmente la soia del concentrato
Impact of Emotional Intelligence on Burnout among Spanish Teachers: A Mediation Study
2021
espanolLa utilidad de la inteligencia emocional y su efecto tranquilizador sobre el estres laboral de los profesores han ido cobrando importancia en este campo de investigacion. El objetivo de este estudio ha sido analizar la relacion entre las habilidades emocionales y el sindrome de burnout y si el equilibrio afectivo media esta asociacion. Se han utilizado modelos de ecuaciones estructurales con datos de autoinforme de 200 profesores cuya edad estaba comprendida entre los 22 y los 64 anos (M = 44.97, SD = 9.31, 73.50% mujeres). Se utilizo un diseno transversal para el estudio. Los resultados mostraron un efecto significativo directo e indirecto de la claridad y de la reparacion emocional…
Effects of a Brief Web-Based "Social Norms"-Intervention on Alcohol, Tobacco and Cannabis Use Among German University Students: Results of a Cluster-…
2021
Background and Aim: “Social norms” (SN)-interventions are aimed at changing existing misperceptions regarding peer substance use by providing feedback on actual norms, thereby affecting personal substance use. It is unknown whether SN-intervention effects previously demonstrated in US students can be replicated in German students. The aim of the INSIST-study was to examine the effects of a web-based SN-intervention on substance use.Design: Cluster-controlled trial.Setting: Eight Universities in Germany.Participants and Measurements: Students were recruited at four intervention vs. four delayed intervention control Universities. 4,463 students completed baseline, 1,255 students (59% female) …
Impact des facteurs nutritionnels pendant et après cancer
2021
Nutritional factors (diet, weight, alcohol, physical activity) are identified as factors having an impact on the onset of several cancer sites. Less abundant scientific data also underline their impact on the tumor progression. A review of the scientific literature was carried out by a group of experts established by the French National Cancer Institute (INCa) to better document the influence of nutritional factors during and after cancer on outcomes such as overall mortality, cancer specific mortality, recurrence, second primary cancers and quality of life. This analysis of the literature completes messages of reduction of alcohol consumption, prevention of undernutrition or excess weight …
Consultations de tabacologie pendant le mois sans tabac : profil des fumeurs et sevrage
2021
Resume Introduction En novembre 2016, la France a mis en place l’operation « Mois sans tabac ». L’objectif de cette etude consistait a comparer les caracteristiques des fumeurs et le taux d’arret a un mois en consultation de tabacologie avant et apres cette mise en place. Methodes Dans la base nationale CDTnet, 1943 fumeurs avaient effectue au moins 28 jours de suivi. Leurs caracteristiques et statut tabagique ont ete compares entre novembre 2014 et 2015 versus novembre 2016 et 2017. Les facteurs predictifs de l’abstinence ont ete determines par des modeles de regression logistique. Resultats Une augmentation significative du nombre de consultations de 6,9 % a ete observee en 2016–2017 vers…
Real‐world evidence of tisagenlecleucel for the treatment of relapsed or refractory large B‐cell lymphoma
2021
Abstract Tisagenlecleucel (tisa‐cel) is a second‐generation autologous CD19‐targeted chimeric antigen receptor (CAR) T‐cell therapy approved for relapsed/refractory (R/R) large B‐cell lymphoma (LBCL). The approval was based on the results of phase II JULIET trial, with a best overall response rate (ORR) and complete response (CR) rate in infused patients of 52% and 40%, respectively. We report outcomes with tisa‐cel in the standard‐of‐care (SOC) setting for R/R LBCL. Data from all patients with R/R LBCL who underwent leukapheresis from December 2018 until June 2020 with the intent to receive SOC tisa‐cel were retrospectively collected at 10 Spanish institutions. Toxicities were graded accor…
The standing knee lift test is not a useful screening tool for time loss from low back pain in youth basketball and floorball players
2021
Abstract Objectives The aim of this study was to investigate the association between pelvic kinematics during the standing knee lift (SKL) test and low back pain (LBP) in youth floorball and basketball players. Design A prospective cohort study. Setting Finnish elite youth floorball and basketball players. Participants Finnish elite youth female and male floorball and basketball players (n = 258, mean age 15.7 ± 1.8). Main outcome measures LBP resulting in time loss from practice and games was recorded over a 12-month period and verified by a study physician. Associations between LBP and sagittal plane pelvic tilt and frontal plane pelvic obliquity during the SKL test as measured at baselin…
Recovery-Stress Response of Blood-Based Biomarkers
2021
The purpose of this study was to investigate blood-based biomarkers and their regulation with regard to different recovery-stress states. A total of 35 male elite athletes (13 badminton, 22 soccer players) were recruited, and two venous blood samples were taken: one in a ‘recovered’ state (REC) after a minimum of one-day rest from exercise and another one in a ‘non-recovered’ state (NOR) after a habitual loading microcycle. Overall, 23 blood-based biomarkers of different physiologic domains, which address inflammation, muscle damage, and tissue repair, were analyzed by Luminex assays. Across all athletes, only creatine kinase (CK), interleukin (IL-) 6, and IL-17A showed higher concentration…
What drives brand love and purchase intentions toward the local food distribution system? A study of social media-based REKO (fair consumption) groups
2021
Local food is gaining increasing popularity among consumers due to its association with sustainable consumption. However, for a product to be commercially successful, such growing popularity should translate into high purchase intentions and positive associations with the product post-consumption. Although this success has not yet been reflected for local food consumption, research in this area has remained limited. The present study addresses this gap by examining the antecedents of brand love for both the local food distribution system and the local food it distributes. The study thus employs the stimuli-organism-response (SOR) theory, which indicates that certain environmental stimuli in…
P215 Blood-based prognostic biomarkers in Crohn’s patients treated with biologics: a new promising tool to predict endoscopic outcomes
2021
Abstract Background There is a growing need for biomarkers of inflammation to monitor and predict therapeutic outcome in Crohn’s disease (CD) patients. We aimed to evaluate whether the level of circulating blood cells, expressed as ratios (NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; ELR, eosinophil-to-lymphocyte ratio and ENLR, eosinophil*neutrophil-to-lymphocyte ratio), could be used as early prognostic biomarker of endoscopic response (ER) in patients starting biological therapy with infliximab, adalimumab, vedolizumab and ustekinumab. Association with steroid-free clinical remission at week 54 and endoscopic disease activity at baseline, as well as other varia…
Microwave Ablation for Metastatic Spinal Tumors
2021
Visioni dell’America. Viaggio, spazialità e narrazione in De Amicis e Amado
2021
Nella prospettiva della geografia culturale l’odeporica offre l’opportunità di studiare alcune dinamiche di (ri)produzione simbolica relative al modo di concepire e rappresentare concetti chiave quali lo spazio, il paesaggio e le interazioni umane. Questo lavoro, partendo dall’analisi di alcuni brani significativi di due raccolte di scritti, In America (1897) di Edmondo De Amicis e In giro per le Americhe (2001) di Jorge Amado, studia, con un approccio geografico-culturale e semiotico, le modalità di costruzione e descrizione dello spazio fisico e simbolico comprese le «frontiere», nonché le interazioni e la socialità attraverso la testualizzazione di esperienze diverse. La comparazione fra…
Risk Management for Sustainable Sovereign Debt Financing
2021
We model sovereign debt sustainability with optimal financing decisions under macroeconomic, financial, and fiscal uncertainty, with endogenous risk and term premia. Using a coherent risk measure we trade-off debt stock and flow risks subject to sustainability constraints. We optimize static and dynamic financing strategies and demonstrate economically significant savings from optimal financing compared with simple rules and consols, and find that optimizing the trade-offs can be critical for sustainability. The model quantifies minimum refinancing risk and maximum rate of debt reduction that a sovereign can achieve given its economic fundamentals, and an extension identifies optimal timing…
Diet and environmental factors affecting reproduction
2021
Abstract Diet and exposure to certain chemical compounds related to industrial development could be responsible for the increase in the incidence of human reproductive diseases and the consequent decrease in reproductive function worldwide. The role of diet and environment in fertility has received more attention in recent years because nutrition and exposure to contaminants can affect fecundity in women of reproductive age. Here, we review how diet could affect reproduction. Furthermore, we will review how the most ubiquitous contaminants could disrupt endometrial receptivity and implantation, focusing also on clinical studies performed in the last years.
The temporal dimension in the understanding of maternal sensitivity in caregiver-infant interactions: The 'Early Mother-Child Interaction Coding Syst…
2021
Abstract Caregiver-child interaction is known to play a central role in children’s socioemotional development, yet the diversity of measures commonly used to evaluate it call into question the nature of the construct being assessed. Contingency within caregiver-child interactions has been identified as a key dyadic process that requires taking a temporal perspective to evaluating interactions. The Early Mother-Child Interaction Coding System is a psychometrically sound measure that sequentially code the flow of interactive and non-interactive behaviours within a caregiver-infant system. Its use of the framework of nonlinear dynamical systems (NDS) expands our understanding of contingent car…
Regeneration units for thermolytic salts applications in water & power production: State of the art, experimental and modelling assessment
2021
Abstract Thermolytic solutions are often proposed as high salinity or “draw” stream to generate a chemical potential driving force in Salinity Gradient Power (SGP) and Forward Osmosis (FO) technologies. Depleted “draw” solutions exiting the process can be regenerated by a thermal process powered at very-low grade heat, which is able to decompose the salt into gaseous ammonia and carbon dioxide, which can be stripped and then reabsorbed in the draw solution, restoring its initial concentration. In this work, two different experimental prototypes for the regeneration of ammonium bicarbonate aqueous solution were designed, built and tested. The effect of several operating parameters on the reg…
Predicting sediment deposition rate in check-dams using machine learning techniques and high-resolution DEMs
2021
Sediments accumulated in check dams are a valuable measure to estimate soil erosion rates. Here, geographic information systems (GIS) and three machine learning techniques (MARS-multivariate adaptive regression splines, RF-random forest and SVM-support vector machine) were used, for the first time, to predict sediment deposition rate (SR) in check-dams located in six watersheds in SW Spain. There, 160 dry-stone check dams (~ 77.8 check-dams km−2), accumulated sediments during a period that varied from 11 to 23 years. The SR was estimated in former research using a topographical method and a high-resolution Digital Elevation Model (DEM) (average of 0.14 m3 ha−1 year−1). Nine environmental-to…
Ten essential features of European dual career development environments: A multiple case study
2021
Aim: Dual career development environments (DCDEs) support athletes’ effort in combining their competitive sporting careers with education or work. The characteristics of the environments may differ across cultures. The aim was to identify essential features of DCDEs based on a cross-case analysis of seven European DCDEs in Belgium, Denmark, Finland, Slovenia, Spain, Sweden, and the United Kingdom within the Erasmus+ Sport project “Ecology of Dual Career”. Design: The study was designed as a multiple case study and based on two holistic ecological working models (Henriksen et al., 2020). The cross-case analysis included series of focus group discussions, in which two-three researchers from e…
Kerr Optical Frequency Combs With Multi-FSR Mode Spacing in Silica Microspheres
2021
We experimentally demonstrate Kerr optical frequency combs (OFCs) with mode spacing of 1, 2, 3, 5, 6, and 8 free spectral ranges (FSRs) corresponding to 0.4, 0.8, 1.2, 2, 2.4, and 3.2 THz, respectively, in silica microspheres pumped by CW C-band lasers in the anomalous dispersion range. Experimental realizations are based on using standard telecom equipment and components such as SMF-28e fiber for producing microspheres and fiber tapers for pump coupling and OFC outcoupling. Numerical simulation is performed to support the experimental results and explain the observed spectral asymmetry in OFCs by the influence of the 3rd-order dispersion.
false
2021
Organizations often learn vicariously by observing what other organizations do. Our study examines vicarious learning–related communication through which individuals share their observations with other organizational members. Most students and members of present-day organizations would expect that this communication is driven by a prodevelopment logic—that communication serves the purpose of organizational improvement and competitiveness. Our unique historical evidence on learning-related communication over multiple decades shows that the subjective and collective attitude toward prodevelopment communication may be ideologically conditioned. Prodevelopment communication is the norm in capi…
Parent–Infant Attachment Insecurity and Emotional Eating in Adolescence: Mediation through Emotion Suppression and Alexithymia
2021
Contains fulltext : 233652.pdf (Publisher’s version ) (Open Access) Emotional eating (EE), the propensity to eat in response to emotions, is thought to have its origins in the early parent-infant relationship. This study tested the hypothesis that infant attachment insecurity results in EE in adolescence through the increased use of the emotion regulation strategy suppression of emotions and subsequent alexithymia. At the age of 15 months, parent-infant attachment security (n = 129) was observed with two abbreviated attachment measures: the shortened strange situation procedure (SSSP), and the shortened attachment Q-set (S-AQS). At the age of 12 years, children completed self-report questio…
On irreducible products of characters
2021
Abstract We study the problem when the product of two non-linear Galois conjugate characters of a finite group is irreducible. We also prove new results on irreducible tensor products of cross-characteristic Brauer characters of quasisimple groups of Lie type.