showing 36 of ~574560 from 574555 documents
VALUTAZIONE DEL GRASSO EPICARDICO MEDIANTE TC
2021
Corrigendum: Association Between Current Physical Activity and Current Perceived Anxiety and Mood in the Initial Phase of COVID-19 Confinement
2021
The World Health Organization (WHO) has declared a world pandemic due to COVID-19, and several enacted measures such as compulsory confinement may have collateral consequences on both physical and mental health. We aimed to investigate associations between current physical activity (PA) and current perceived anxiety and mood among a sample of Spanish adults confined due to COVID-19 restrictions of movement. Using an online survey, we collected data on the Spanish adult population regarding health habits during the first days of enacted confinement. A total of 2250 participants (54.8% women) aged 35.3 (SD 13.6) completed the survey, which included questions about sociodemographic characteris…
Impact of Narrow Band Imaging in Pre-Operative Assessment of Suspicious Oral Cavity Lesions: A Systematic Review
2021
Introduction: Narrow band imaging (NBI) is a powerful tool that allows visualizing the mucosal and submucosal vasculature. Among the available diagnostic techniques, NBI is one of the most valid for early detection of oral squamous cell carcinoma (OSCC). Materials and Methods: We carried out a bibliographic search in PubMed, Scopus and Web of Science databases using relevant keywords. Articles selected were screened by two independent authors based on inclusion and exclusion criteria. Nine papers were singled out according to the eligibility criteria and included in this review. We investigated the articles for pooled sensitivity, specificity, accuracy, positive predictive value and negativ…
Le portage de repas à domicile : processus d’installation et d’appropriation de ce service par les personnes âgées en perte d’autonomie
2021
Resume Introduction La survenue d’incapacites physiques ou cognitives peut conduire une personne âgee a deleguer certaines tâches de la vie courante a un aidant. Si la mise en place d’aides permet le maintien a domicile et est fortement plebiscitee par les seniors, la perte d’autonomie constitue neanmoins un element de rupture dans sa vie d’une personne. Objectif Notre objectif etait d’explorer les processus d’installation d’un service de livraison de repas a domicile et les mecanismes d’appropriation de ce service par les beneficiaires. Methode Des entretiens semi-directifs ont ete realises aupres de 30 beneficiaires d’un service de livraison de repas (21 femmes ; 70–97 ans). Resultat L’an…
Individualism, collectivism and reward crowdfunding contribution intention and behavior
2021
Abstract The study examines the role of the individualism-collectivism (IDV) cultural dimension in reward crowdfunding contribution intentionality and behavior. An extended Theory of Planned Behavior framework is used for comparative analysis using survey data collected from users of national platforms from opposing cultures along the IDV dimension – China and Finland. Main findings suggest that: attitudes are positively associated with information sharing and financial contribution intentions in both cultures; collectivism enhances the effects of subjective norms on both intentions; behavior control is more strongly observed in individualistic cultures; and information sharing intentions a…
Mitochondrial DNA haplogroups J and T increase the risk of glioma.
2021
The presence of different sets of mitochondrial polymorphisms generated by the accumulation of mutations in different maternal lineages has allowed differentiating mitochondrial haplogroups in human populations. These polymorphisms, in turn, may have effects at the phenotypic level, considering a possible contribution of these germinal mutations to the development of certain diseases such as cancer. The main goal of the present study is to establish a possible association between mitochondrial haplogroups and the risk of suffering glioma. Blood samples were obtained from 32 patients from Catalonia (Spain) diagnosed with different grades of glioma (II, III and IV), according to the World Hea…
Bounds on the triplet fermions in type-III seesaw and implications for collider searches
2021
Type-III seesaw is a simple extension of the Standard Model~(SM) with the SU$(2)_\text{L}$ triplet fermion with zero hypercharge. It can explain the origin of the tiny neutrino mass and flavor mixing. After the electroweak symmetry breaking the light neutrino mass is generated by the seesaw mechanism which further ensures the mixings between the light neutrino and heavy neutral lepton mass eigenstates. If the triplet fermions are around the electroweak scale having sizable mixings with the SM sector allowed by the correct gauge symmetry, they can be produced at the high energy colliders leaving a variety of characteristic signatures. Based on a simple and concrete realizations of the model …
Sensorimotor training prior total knee arthroplasty and effects on functional outcome: A systematic review and meta-analysis.
2021
Abstract Background Altered muscle activation patterns and proprioception, loss of strength, and weight bearing asymmetries are common limitations after total knee arthroplasty, which can also affect balance. Therefore, preoperative sensorimotor training has been proposed to enhance surgical outcome. Research question Is preoperative sensorimotor training effective in improving functional outcome in patients undergoing total knee arthroplasty? Does preoperative sensorimotor training affect secondary outcomes such as balance, pain, and quality of life? Methods A systematic review and meta-analysis were conducted by searching PEDro, MEDLINE, Embase, Cochrane Library, and Scopus databases from…
Cristianesimo e modernità politica. il problema teologico-politico nell'ultimo Kant
2021
In this paper I will analyse the religious issue in the late Kantian work. I argue that Kant’s reflections on Christianity have to be strictly connected with those on law and history. This connection lead us to the political theological problem which is crucial in the case of Hegel as well. In the Encyclopedia Hegel explicitly takes inspiration from Kant who thinks that the problem of that age is the relation between religion and law. That is why Kant cannot be considered a liberal thinker because religion is not a mere private question for him but it has a public importance within his modern conception of history. In this sense, I also argue that Kant’s judg-ment on Christianity is more ne…
The efficacy of single suture for exit site wound closure and stabilization of hemodialysis central tunneled catheter
2021
Introduction: The majority of the end-stage renal disease patients begin hemodialysis with the central tunneled catheter as a permanent or bridge vascular access. The procedure of central tunneled catheter insertion can be complicated by exit site bleeding, prolonged tunnel healing, and infection. The study aimed at evaluating whether the catheter exit site wound closing with a single-suture method is equally effective as the double suture method, which is most frequently applied. The assumption was that the single-suture method, which is less traumatizing for the skin, could offer an advantage for the patients with “paper” skin, that is, elderly, after long-term immunosuppressive treatment…
The Nexus between Sovereign CDS and Stock Market Volatility: New Evidence
2021
This paper extends the studies published to date by performing an analysis of the causal relationships between sovereign CDS spreads and the estimated conditional volatility of stock indices. This estimation is performed using a vector autoregressive model (VAR) and dynamically applying the Granger causality test. The conditional volatility of the stock market has been obtained through various univariate GARCH models. This methodology allows us to study the information transmissions, both unidirectional and bidirectional, that occur between CDS spreads and stock volatility between 2004 and 2020. We conclude that CDS spread returns cause (in the Granger sense) conditional stock volatility, m…
Electrocardiographic Abnormalities and Mortality in Epilepsy Patients
2021
Background and Objectives: People with epilepsy (PWE) have a 2–3 times higher mortality rate than the general population. Sudden unexpected death in epilepsy (SUDEP) comprises a significant proportion of premature deaths, whereas sudden cardiac death (SCD) is among the leading causes of sudden death in the general population. Cardiac pathologies are significantly more prevalent in PWE. Whether electrocardiographic (ECG) parameters are associated with remote death in PWE has yet to be elucidated. The study objective was to assess whether interictal ECG parameters are associated with mortality in the long-term. Materials and Methods: The study involved 471 epilepsy patients who were hospitali…
Reversed Polarity bi-tDCS over M1 during a Five Days Motor Task Training Did Not Influenced Motor Learning. A Triple-Blind Clinical Trial
2021
This article belongs to the Special Issue Applications of Neuromodulation on Pain and Motor Learning.
Diferencias de opinión sobre el uso de los test: su relación con la edad el género y el sector laboral
2021
Tests are important tools that help psychologists to make decisions about people. In order to propose actions aimed at improving the use of tests, it is important to determine what factors relate to psychologists’ opinions about testing practices. In this study we assess the role of three factors: gender, age, and job sector (public vs. private). In addition, we compare practitioners’ opinions with those reported by professors of test-related subjects (psychometrics, and psychological and psycho- educational assessment). After analyzing a sample of 1,248 members of the Spanish Psychological Association and 95 professors from different universities, results show some differences in opinions …
Statin intolerance: new data and further options for treatment
2021
Purpose of review Hypercholesterolemia is a major risk factor for cardiovascular diseases. Administration of statins represents the cornerstone of the prevention and treatment of cardiovascular disease, with demonstrated long-term safety and efficacy. This review aims to revisit statin intolerance mechanisms, as well as to discuss new data and therapeutic options. Recent findings Although statins are well tolerated, myopathy and other adverse effects are a challenging problem, being the main reason for poor adherence to treatment and failure in lowering cardiovascular risk. Statin intolerance is the subject of ongoing research, as these drugs are widely used. There are alternative options o…
Improving checkpointing intervals by considering individual job failure probabilities
2021
Checkpointing is a popular resilience method in HPC and its efficiency highly depends on the choice of the checkpoint interval. Standard analytical approaches optimize intervals for big, long-running jobs that fail with high probability, while they are unable to minimize checkpointing overheads for jobs with a low or medium probability of failing. Nevertheless, our analysis of batch traces of four HPC systems shows that these jobs are extremely common.We therefore propose an iterative checkpointing algorithm to compute efficient intervals for jobs with a medium risk of failure. The method also supports big and long-running jobs by converging to the results of various traditional methods for…
THE ROLE OF FINANCIAL SUPPORT FOR THE PERFORMANCE AND SURVIVAL OF MICRO-ENTERPRISES
2021
The research was supported by the NATIONAL RESEARCH PROGRAMME “LATVIAN HERITAGE AND FUTURE CHALLENGES FOR THE SUSTAINABILITY OF THE STATE” project “CHALLENGES FOR THE LATVIAN STATE AND SOCIETY AND THE SOLUTIONS IN INTERNATIONAL CONTEXT" (INTERFRAME-LV, Project No.VPP-IZM-2018/1-0005).
Analysis of the Gut Microbiota: An Emerging Source of Biomarkers for Immune Checkpoint Blockade Therapy in Non-Small Cell Lung Cancer
2021
Simple Summary The immune checkpoint blockade (ICB), and concretely the blockade of the PD1/PDL1 axis, has opened up a new standard of treatment for non-small cell lung cancer (NSCLC). However, despite substantial advances in clinical care, many patients still remain refractory to these therapies. Biomarkers such as PD-L1 expression and tumor mutational burden have been associated with ICB efficacy, but the mechanisms underlying variable responses are not yet fully understood. Recently, the differential composition of the gut microbiota was studied as one of the variables accounting for interpatient heterogeneity in ICB responses. To better understand the potential role of the gut microbiot…
Consultations de tabacologie pendant le mois sans tabac : profil des fumeurs et sevrage
2021
Resume Introduction En novembre 2016, la France a mis en place l’operation « Mois sans tabac ». L’objectif de cette etude consistait a comparer les caracteristiques des fumeurs et le taux d’arret a un mois en consultation de tabacologie avant et apres cette mise en place. Methodes Dans la base nationale CDTnet, 1943 fumeurs avaient effectue au moins 28 jours de suivi. Leurs caracteristiques et statut tabagique ont ete compares entre novembre 2014 et 2015 versus novembre 2016 et 2017. Les facteurs predictifs de l’abstinence ont ete determines par des modeles de regression logistique. Resultats Une augmentation significative du nombre de consultations de 6,9 % a ete observee en 2016–2017 vers…
Auswirkungen der COVID-19-Pandemie auf den Therapieverlauf bei Kindern mit einer Sprachentwicklungsstörung
2021
Mittelhochdeutsche Sprachzeugnisse oder romantische Fälschungen?
2021
Abstract For some decades, the authenticity of the German inscriptions of the castle Wildenberg in the Odenwald was rejected repeatedly. If they were created around 1200, they would be among the oldest known inscriptions written in German. This study attempts to verify the widely accepted assumption, that the inscriptions were ›forgeries‹ of the 19th century, based on epigraphic and linguistic criteria. It becomes apparent that evidence for ›forgery‹ cannot be provided based on the forms of the letters. A comparison of the preserved word and name forms shows, however, that the doubts concerning the authenticity of the inscriptions at the gate tower of the castle can be substantiated linguis…
Mycobacterium tuberculosis Rv2145c Promotes Intracellular Survival by STAT3 and IL-10 Receptor Signaling
2021
Although Mycobacterium tuberculosis (Mtb) is an intracellular pathogen in phagocytic cells, the factors and mechanisms by which they invade and persist in host cells are still not well understood. Characterization of the bacterial proteins modulating macrophage function is essential for understanding tuberculosis pathogenesis and bacterial virulence. Here we investigated the pathogenic role of the Rv2145c protein in stimulating IL-10 production. We first found that recombinant Rv2145c stimulated bone marrow-derived macrophages (BMDMs) to secrete IL-10, IL-6 and TNF-α but not IL-12p70 and to increase the expression of surface molecules through the MAPK, NF-κB, and TLR4 pathways and enhanced …
Tonnerre de Brest ! Des Journées de Recherche Respiratoires 2020 pas comme les autres…
2021
International audience; Tentons un peu d’oublier l’année 2020, mais pas complètement . . . C’est une année qui nousaura conduits à des envies et des visions différentes. Les rencontres conviviales et bien-veillantes qui ponctuent nos journées chaque année au mois d’octobre depuis 2005 n’ontpu se dérouler comme prévues, mais nous étions tous présents pour les 16esJournées deRecherche Respiratoire (J2R) le 16 octobre 2020, bien que devant nos écrans !Nous y avons cru jusqu’au bout et pensions pouvoir bénéficier de la fin de la fenêtreestivale, le programme était prêt et nos hôtes Brestois (nous ne remercierons jamais assezles équipes des Prs Francis Couturaud et Christophe Leroyer) avaient pe…
A. Bavelas, 1950, Communication Patterns in Task-Oriented Groups. Version bilingue et commentée
2021
Ce document du groupe fmr présente une version bilingue et commentée de l'article d'Alex Bavelas, Communication Patterns in Task-Oriented Groups, paru en 1950 dans la revue Journal of the Acoustical Society of America. S'appuyant sur les seuls travaux de Kurt Lewin et de ses élèves, et donc ne mobilisant ni la sociométrie ni la théorie des graphes au sens strict, l'auteur propose un ensemble de mesures permettant de mesurer l'efficacité de la communication au sein d'une structure donnée. Cet article a eu une influence importante dans différents champs de recherche (analyse de réseaux sociaux, management, psychologie, etc.).
Parte III, Capitolo III, Fondo e azienda agricola
2021
Questo volume nasce dalla necessità di offrire una lettura aggiornata, contemporanea appunto, delle peculiari regole che tradizionalmente han- no attribuito al Diritto agrario un carattere di specialità. Facciamo riferimento alle norme che in un’ottica di programmazione di un settore produttivo peculiare disciplinano l’impresa agricola, la proprietà terriera, i contratti agrari, il lavoro agricolo, il credito agrario, il mercato dei prodotti agricoli. Regole la cui chiave di lettura è sempre passata dalla considerazione dell’esistenza di un legame stretto tra “agricoltura” e “terra”, considerazione che non riteniamo superata, ma piuttosto aggiornata, dalle numerose innovazioni legislati…
Use of Kluyveromyces marxianus to Increase Free Monoterpenes and Aliphatic Esters in White Wines
2021
An increasing interest in novel wine productions is focused on non-Saccharomyces yeasts due to their potential in improving sensory profiles. Although Kluyveromyces marxianus has been originally isolated from grapes and its enzymatic activities are used in oenology, rarely it has been used as co-starter. The K. marxianus Km L2009 strain has been characterized here and selected as a co-starter both at laboratory- and winery-scale fermentation. The Km L2009 strain showed growth of up to 40 (mg/L) of sulfites and 6% (v/v) of ethanol. Gas chromatographic analysis demonstrates that wines produced by mixed fermentation contain remarkably higher quantities of free monoterpenes and aliphatic esters…
Correspondences of Brauer characters and Sylow subgroup normalizers
2021
Abstract Let p > 3 and q ≠ p be primes, let G be a finite q-solvable group and let P ∈ Syl p ( G ) . Then G has a unique irreducible q-Brauer character of p ′ -degree lying over 1 P if and only if N G ( P ) / P is a q-group. One direction of this result follows from a natural McKay bijection of p ′ -degree irreducible q-Brauer characters, which is obtained under suitable conditions.
Source Mechanisms of Laboratory Earthquakes During Fault Nucleation and Formation
2021
Identifying deformation and pre-failure mechanisms preceding faulting is key for fault mechanics and for interpreting precursors to fault rupture. This study presents the results of a new and robust derivation of first motion polarity focal mechanism solutions (FMS) applied to acoustic emission (AE). FMS are solved using a least squares minimization of the fit between projected polarity measurements and the deviatoric stress field induced by dilatational (T-type), shearing (S-type), and compressional (C-type) sources. 4 × 10 cm cylindrical samples of Alzo Granite (AG, porosity <1%) and Darley Dale Sandstone (DDS, porosity ≈14%) underwent conventional triaxial tests in order to investigat…
Heat and work fluxes in thermoelectric coolers
2021
Abstract Thermodynamics considers heat and work as the observables of energy. Then, in a non-equilibrium process, the fluxes of heat, work and energy are related. The expressions for the heat and energy flux densities are well known; although several conventions have been adopted. The work flux density defined from the heat and energy flux densities can be very useful in describing the energy balance when chosen to emphasize observable quantities. This paper discusses the advantages of the use of the conduction heat flux density given by Fourier’s law and a work flux density defined from it. As a case study, heat and work fluxes are evaluated in the elements of a thermoelectric cooler using…
Toxicity as prime selection criterion among SARS-active herbal medications
2021
We present here a new selection criterion for prioritizing research on efficacious drugs for the fight against COVID-19: the relative toxicity versus safety of herbal medications, which were effective against SARS in the 2002/2003 epidemic. We rank these medicines according to their toxicity versus safety as basis for preferential rapid research on their potential in the treatment of COVID-19. The data demonstrate that from toxicological information nothing speaks against immediate investigation on, followed by rapid implementation of Lonicera japonica, Morus alba, Forsythia suspensa, and Codonopsis spec. for treatment of COVID-19 patients. Glycyrrhiza spec. and Panax ginseng are ranked in …
Contactless generation of cavitation in high temperature liquid metals and its impact on particle dispersion in solidified iron and steel samples
2021
Abstract A recently developed method for the contactless magnetic generation of cavitation is demonstrated for high-melting-point metals. The approach is based on the floating-zone technique, which is truly contactless and crucible-free as it uses electromagnetic forces. Using this method, ultra-high-temperature ceramic particles, such as TiN, TiB2 and TiC, are admixed in liquid iron and 316L steel. The dispersion and particle refinement caused by cavitation treatment during melting and solidification are investigated. Magnetic fields up to 8 T that correspond to pressure oscillation amplitude of 0.83 MPa are used. The signal emitted by the collapsing bubbles is captured and visualized for …
Scientific mapping of the research output on hypertension in children and adolescents, 2010-2018.
2021
Objective The area of pediatric hypertension (HTN) research has seen substantial progress over the last two decades, but no bibliometric analysis has yet been undertaken to describe these advances. This study aims to describe the published research examining HTN in children and adolescents from 2000 to 2018. Methods Articles were retrieved using PubMed and the Web of Science. Analyses were performed to quantify the evolution of scientific output, identifying the leading journals, authors, and countries as well as the existing collaboration networks. Likewise, we identified the most cited articles, describing their document type, main topic focus, and the age of the patients studied. Results…
Ten essential features of European dual career development environments: A multiple case study
2021
Aim: Dual career development environments (DCDEs) support athletes’ effort in combining their competitive sporting careers with education or work. The characteristics of the environments may differ across cultures. The aim was to identify essential features of DCDEs based on a cross-case analysis of seven European DCDEs in Belgium, Denmark, Finland, Slovenia, Spain, Sweden, and the United Kingdom within the Erasmus+ Sport project “Ecology of Dual Career”. Design: The study was designed as a multiple case study and based on two holistic ecological working models (Henriksen et al., 2020). The cross-case analysis included series of focus group discussions, in which two-three researchers from e…
More Severe COVID-19 in Patients With Active Cancer: Results of a Multicenter Cohort Study
2021
BackgroundThe aim of the study was to compare coronavirus disease 2019 (COVID-19) severity presentation between oncologic and non-oncologic patients and to evaluate the impact of cancer type and stage on COVID-19 course.MethodsWe performed a multicentre, retrospective study involving 13 COVID-19 Units in Campania region from February to May 2020. We defined as severe COVID-19 presentation the cases that required mechanical ventilation and/or admission to Intensive Care Units (ICU) and/or in case of death.ResultsWe enrolled 371 COVID-19 patients, of whom 34 (9.2%) had a history or a diagnosis of cancer (24 solid, 6 onco-hematological). Oncologic patients were older (p&lt;0.001), had more…
Cultura e Amministrazione nella transizione digitale
2021
The research concerns cultural heritage and, in its overall dimension, the evolution of culture, considered in the light of the very significant transformations in the contemporary global world, which in an unprecedented and expansive way affect its conceptual framework, also in terms of the relationship with the person, considered in the role of user and co-creator of the cultural value; and they also invest public duty which is entrusted with tasks of protection and promotion of both the development of the person and of culture. The analysis points out the overcoming of a markedly materialistic vision, the shift of attention from the conservative dynamics to the management profiles of cul…
Many Images for a Continent. An Introduction
2021
For too long, the European Union has presented itself as a haven for bureaucrats, united by a hegemonic will practiced through the hyper-standardization of every aspect of social life. The result of this representation, so often weaponised by political forces hostile to the European project, has also been the reason the many images (normative acts, community projects, cultural initiatives etc.) that constitute the European discourse struggle to be recognized and read into a basic everyday narrative capable of shaping a European horizon of shared destinies. This book recognises the importance of the European discourse in its symbolic dimension and the need for it to be circulated via a wide-…