false

2021

The purpose of the study was to examine the effects of progressively increased training intensity or volume on the nocturnal heart rate (HR) and heart rate variability (HRV), countermovement jump, perceived recovery, and heart rate-running speed index (HR-RS index). Another aim was to analyze how observed patterns during the training period in these monitoring variables were associated with the changes in endurance performance. Thirty recreationally trained participants performed a 10-week control period of regular training and a 10-week training period of either increased training intensity (INT, n = 13) or volume (VOL, n = 17). Changes in endurance performance were assessed by an incremen…

The WtmsDW Locus on Wheat Chromosome 2B Controls Major Natural Variation for Floret Sterility Responses to Heat Stress at Booting Stage

2021

Heat stress at booting stage causes significant losses to floret fertility (grain set) and hence yield in wheat (Triticum aestivum L.); however, there is a lack of well-characterized sources of tolerance to this type of stress. Here, we describe the genetic analysis of booting stage heat tolerance in a cross between the Australian cultivars Drysdale (intolerant) and Waagan (tolerant), leading to the definition of a major-effect tolerance locus on the short arm of chromosome 2B, Wheat thermosensitive male sterile Drysdale/Waagan (WtmsDW). WtmsDW offsets between 44 and 65% of the losses in grain set due to heat, suggesting that it offers significant value for marker-assisted tolerance breedin…

Multiphysics Optimization for Water-Cooled Breeding Blanket Design Enhancement

2021

The commercial feasibility of the first fusion power plant generation adopting D-T plasma is strongly dependent upon the self-sustainability in terms of tritium fueling. Within such a kind of reactor, the component selected to house the tritium breeding reactions is the breeding blanket, which is further assigned to heat power removal and radiation shielding functions. As a consequence of both its role and position, the breeding blanket is heavily exposed to both surface and volumetric heat loads and, hence, its design requires a typical multiphysics approach, from the neutronics to the thermo-mechanics. During last years, a great deal of effort has been put in the optimization of the breed…

Lifestyle Habits and Mental Health in Light of the Two COVID-19 Pandemic Waves in Sweden, 2020

2021

The COVID-19 pandemic has become a public health emergency of international concern, which may have affected lifestyle habits and mental health. Based on national health profile assessments, this study investigated perceived changes of lifestyle habits in response to the COVID-19 pandemic and associations between perceived lifestyle changes and mental health in Swedish working adults. Among 5599 individuals (50% women, 46.3 years), the majority reported no change (sitting 77%, daily physical activity 71%, exercise 69%, diet 87%, alcohol 90%, and smoking 97%) due to the pandemic. Changes were more pronounced during the first wave (April–June) compared to the second (October–December). Women,…

Twitter sentiment as a weak signal in venture capital financing

2021

Abstract How do venture capitalists (VCs) incorporate weak and strong signals in the valuation of technology-based startups? Based on a sociocognitive perspective of signaling theory, we introduce Twitter sentiment as a novel and weak signal, which we juxtapose with patents as a traditional, strong signal. While we find a positive association between both signals and VCs' venture valuations, our results reveal that Twitter sentiment does not correlate with actual long-term investment success, whereas patents do. Additionally, we identify and test novelty and experience characteristics (i.e., startup age and VC firm experience) as boundary conditions for our proposed signal-valuation relatio…

Leisure-Time and Occupational Physical Activity Associates Differently with Epigenetic Aging

2021

Supplemental digital content is available in the text.

Nastanak i liječenje gigantskih kamenaca ileocekalnog urinskog spremnika u pacijenta liječenog cistektomijom zbog intersticijskog cistitisa: prikaz s…

2021

Cilj: Cilj ovoga rada je prikazati pacijenta s intersticijskim cistitisom u kojega je došlo do stvaranja kamenaca u novoformiranom urinskom spremniku. Prikaz slučaja: Pacijent star 48 godina obrađivan je zbog recidivnih infekcija mokraćnog sustava. Prethodno mu je zbog intersticijskog cistitisa, koji je znatno utjecao na njegovu kvalitetu života, učinjena cistektomija uz oblikovanje urinskog spremnika (Mainz-pouch I). Urološkom obradom pronađena su u području urinskoga spremnika dva velika kamenca dimenzija 77 × 74 mm te 76 × 62 mm uz obostranu hidronefrozu. Kako bi se riješio uzrok rekurentnih urinarnih infekcija, učinjena mu je otvorenim pristupom ekstrakcija oba kamenca. Poslijeoperacijs…

Mycotoxins: Toxicology, Identification and Control

2021

The evaluation of the presence of mycotoxins in different matrices is achieved through different analytical tools (including quantitative or qualitative determinations) [...]

Novel, automated, semi-industrial modular photobioreactor system for cultivation of demanding microalgae that produce fine chemicals - The next story…

2021

Abstract Recently, there has been increased interest in the use of microorganisms in the production of pharmaceuticals, nutraceuticals and energy supply products, which is due to their rapid growth rate and ability to biosynthesize fine chemicals or biotransform specific xenobiotics. To achieve the desired scale of production and optimization of microbial cultures, it is necessary to design bioreactors that enable process automation, control of working parameters, reduction of microbial and chemical contaminations, and culture independence of climate conditions. In response to this need, an original, modular airlift-type photobioreactor system was designed and manufactured. This novel semit…

Three-year follow-up results of the prospective European Multicenter Cohort Study on Cyanoacrylate Embolization for treatment of refluxing great saph…

2021

Abstract Objective Cyanoacrylate closure of refluxing saphenous veins has demonstrated excellent safety and effectiveness results in feasibility and pivotal studies. This article provides the 36-month follow-up results of a prospective, multicenter, nonrandomized cohort study. Methods A total of 70 patients were enrolled in a prospective, multicenter study conducted at seven centers in four European countries and underwent treatment of a solitary refluxing great saphenous vein with endovenous cyanoacrylate embolization without the use of tumescent anesthesia or postprocedure compression stockings. The primary effectiveness end point was freedom from recanalization (closure rate) of the grea…

Evaluation of the xerostomia, taste and smell impairments after Covid-19

2021

Background The purpose of this study was to explore the effects of coronavirus disease 19 (Covid-19) on the oral cavity by evaluating the oral findings in the patients who recovered after treatment. Material and Methods This study involved confirmed Covid-19 patients whose treatment completed at least two weeks ago. A questionnaire consist of eight parts was applied to explore the oral findings after Covid-19. Also stimulated salivary flow rate was evaluated with a salivary flow test. Results 177 patients reached and 107 of them participate in the study. Regarding gender significant differences were found in terms of the presence of taste impairment after treatment (p=0.007), the degree of …

Local electronic structure rearrangements and strong anharmonicity in YH3 under pressures up to 180 GPa

2021

The authors acknowledge the ESRF program committee (Grenoble, France) for the opportunity to perform XAFS and XRD measurements. We are grateful to Prof. Dr Marek Tkacz from the Institute of Physical Chemistry, PAS Kasprzaka 44/52, 01-224 Warsaw, Poland, for high quality YH3 samples and to Dr. José A. Flores-Livas for a fruitful discussion. A.P.M. and A.A.I. acknowledge the Russian Foundation for the Basic Research (grant No 18-02-40001_mega) for financial support. J.P., A.K., and I.P. would like to thank the support of the Latvian Council of Science project No. lzp-2018/2-0353. ISSP UL acknowledge the European Union’s Horizon 2020 Framework Programme H2020-WIDESPREAD-01-20l 6-2017-TeamingPh…

Search for Coherent Elastic Scattering of Solar B8 Neutrinos in the XENON1T Dark Matter Experiment

2021

We report on a search for nuclear recoil signals from solar $^8$B neutrinos elastically scattering off xenon nuclei in XENON1T data, lowering the energy threshold from 2.6 keV to 1.6 keV. We develop a variety of novel techniques to limit the resulting increase in backgrounds near the threshold. No significant $^8$B neutrino-like excess is found in an exposure of 0.6 t $\times$ y. For the first time, we use the non-detection of solar neutrinos to constrain the light yield from 1-2 keV nuclear recoils in liquid xenon, as well as non-standard neutrino-quark interactions. Finally, we improve upon world-leading constraints on dark matter-nucleus interactions for dark matter masses between 3 GeV/…

The story of endurance:Biogeography and the evolutionary history of four Holarctic butterflies with different habitat requirements

2021

Aim: Biogeographical studies on the entire ranges of widely distributed species can change our perception of species’ range dynamics. We studied the effects of Pleistocene glacial cycles on current butterfly species distributions, aiming to uncover complex biogeographic patterns in the Holarctic, a region dramatically affected by Cenozoic climate change. Location: Eurasia and North America. Taxon: Boloria chariclea, Agriades optilete, Carterocephalus palaemon, Oeneis jutta. Methods: We reconstructed the biogeographic history of four butterfly species differing in habitat preferences (B. chariclea – tundra, A. optilete – bogs, C. palaemon – temperate grasslands, O. jutta – taiga), using one …

Finance, globalisation, technology and inequality: Do nonlinearities matter?

2021

Abstract Relying on data for 90 economies over 1970-2015 and panel estimation techniques, we investigate how financial development, globalisation and technology affect income inequality. Our findings reveal significant nonlinearities, consistent with either Ushaped or inverted-U shaped relationships. As such, depending on whether a certain threshold value is achieved, the same determinants of income distribution exert opposite effects in different countries. Globalisation is associated with increasing inequality in most advanced economies, but with falling disparities for the large majority of emerging economies. Technology and financial development lead to increasing inequality for most em…

Long-term oral anticoagulation for atrial fibrillation in low and middle income countries.

2021

With increasing life-expectancy and changing demographics, non-valvular atrial fibrillation (AF) is currently the most common indication for long-term oral anticoagulation (OAC) in low and middle income countries (LMICs). Due to a decreasing trend in the prevalence of rheumatic heart disease (RHD), valve disease as a primary cause of AF now constitutes a small fraction of all people with AF. Moreover, emerging data also indicate that, patients with significant valve disease and AF may have a risk of stroke similar to, if not lower than, those with non-valvular AF. Previous trials of anticoagulation for AF excluded people from LMICs partly because valvular AF constituted a large proportion o…

Effect of Computer-Aided Navigation Techniques on the Accuracy of Endodontic Access Cavities: A Systematic Review and Meta-Analysis

2021

Simple Summary The endodontic access cavity is an essential step in the root canal treatment allowing the access and location of the root canal system. The inaccuracy during the endodontic access cavitie can lead to intraoperative complications such as missed root canals or root perforations, and hence affect the prognosis of the root canal treatment. The development of computer-aided static and dynamic navigation techniques has improved the accuracy of endodontic access cavities and root canal location; however, it is necessary a comparative analysis to clarify which of the computer-aided navigation system is more accurate. This systematic review and meta-analysis aims to clarify the root …

Nonendodontic periapical lesions: a retrospective descriptive study in a Brazilian population

2021

Background Several nonendodontic diseases can occur in the periapical region, resembling endodontic inflammatory conditions. Therefore, the aim of the present study was to determine the frequency of nonendodontic periapical lesions diagnosed in a Brazilian population. Material and Methods The files of two Oral Pathology laboratories were reviewed and all cases including at least one clinical diagnosis of endodontic periapical lesions were selected for the study. After initial selection, demographic and clinical data, clinical diagnosis and final diagnosis were reviewed and tabulated. Final diagnosis included endodontic periapical lesions, and benign and malignant nonendodontic periapical le…

L’accesso a siti giuridici di internet per i soggetti detenuti è un diritto umano

2021

Dalla Corte europea dei diritti dell’uomo giunge un monito sulla tutela della libertà di espressione e di informazione che assume al contempo il valore di un sostegno per le battaglie civili condotte dall’avvocatura turca. È stata riconosciuta, infatti, all’unanimità, una violazione dell’articolo 10 CEDU da parte della Turchia, nel divieto di fruizione di siti internet tecnico giuridici per un difensore in stato di detenzione.

Denoising AVIRIS-NG Data for Generation of New Chlorophyll Indices

2021

The availability of Airborne Visible and Infrared Imaging Spectrometer-Next Generation (AVIRIS-NG) data has enormous possibilities for quantification of Leaf Chlorophyll Content (LCC). The present study used the AVIRIS-NG campaign site of Western India for generation and validation of new chlorophyll indices by denoising the AVIRIS-NG data. For validation, concurrent to AVIRIS-NG flight overpass, field samplings were performed. The acquired AVIRIS-NG was subjected to Spectral Angle Mapper (SAM) classifier for discriminating the crop types. Three smoothing techniques i.e., Fast-Fourier Transform (FFT), Mean and Savitzky-Golay filters were evaluated for their denoising capability. Raw and fil…

Carbon sequestration in French agricultural soils: A spatial economic evaluation

2021

International audience; Soil organic carbon sequestration measures entail costs to farmers with different individual characteristics and located in different areas. A cost‐effective analysis taking into account these heterogeneities is crucial for developing effective public policy aimed at increasing carbon sequestration. We undertake such an analysis focusing on three soil organic carbon sequestration measures: no‐till, extension of temporary grasslands, and hedgerows. Through an optimization model applied to France, our results show that only extension of temporary grasslands can store carbon at low cost, though their potential for carbon sequestration is also low. For an ambitious carbo…

Coping with Burnout Symptoms through Task Significance in Professionals Working with Individuals with Intellectual Disability

2021

ABSTRACT This study examined an intervention that links task significance (one’s job has a positive impact on other people) to burnout symptoms of professionals working in organizations for individuals with intellectual disability. Professionals assigned to the experimental condition participated in teams designed to enhance the positive impact of their work on others (task significance). To do so, teams focused on a task to improve the quality of life of individuals with intellectual disability. Professionals assigned to the control condition did not participate in these teams, and they continued with their usual work. All the participating professionals answered a questionnaire abou…

Corrigendum to “Genetic characterization of Anaplasma phagocytophilum strains from goats (Capra aegagrus hircus) and water buffalo (Bubalus bubalis) …

2021

L’étiquetage des spécialités pharmaceutiques

2021

En France, l’etiquetage des specialites pharmaceutiques est regi par le Code de la sante publique. Il est preimprime sur le conditionnement exterieur qui peut comporter des signes ou des pictogrammes mettant en avant certaines informations utiles pour les patients.

Asymmetry in inter-municipal cooperation in health services - How does it affect service quality and autonomy?

2021

Throughout Europe, local health services are increasingly being provided through various forms of inter-municipal cooperation (IMC). One of the most common forms of IMC is when small municipalities delegate the operational responsibility for providing health services to a larger host municipality. However, despite the size asymmetry usually inherent in this type of IMC, this aspect has largely been neglected in the existing literature, which mainly focuses on the size of individual municipalities. Based on data from 97 partner municipalities and 25 host municipalities in Norway, this study examines how varying degrees of size asymmetry between them affect the perceived service quality and l…

PS01.04 International Tailored Chemotherapy Adjuvant Trial : ITACA Trial. Final Results

2021

How work and family caregiving responsibilities interplay and affect registered dietitian nutritionists and their work: A national survey.

2021

Healthcare professionals provide paid care at work and potentially have caregiving responsibilities outside of work; work responsibilities in addition to child and/or elder care is considered double- or triple-duty care. Employees may experience conflict and/or enrichment as their work and family responsibilities interface. This study’s purpose is to explore the work and family interface of Registered Dietitian Nutritionists (RDNs), determine the prevalence of work-family conflict and enrichment, and identify characteristics associated with higher work-family conflict and enrichment scores. A survey instrument assessing caregiving responsibilities and work-family conflict and enrichment was…

A general nonexistence result for inhomogeneous semilinear wave equations with double damping and potential terms

2021

Abstract We investigate the large-time behavior of solutions for a class of inhomogeneous semilinear wave equations involving double damping and potential terms. Namely, we first establish a general criterium for the absence of global weak solutions. Next, some special cases of potential and inhomogeneous terms are studied. In particular, when the inhomogeneous term depends only on the variable space, the Fujita critical exponent and the second critical exponent in the sense of Lee and Ni are derived.

false

2021

Abstract Objectives To examine how gender functions in the narrative construction of dual career styles, and how these styles impact the (dis)continuation of a dual career pathway. Design Longitudinal qualitative study. Method Life story interviews with 18 talented Finnish athletes (10 cis women, 8 cis men) at four points in time – when they averaged 16, 17, 19, and 20 years of age – followed by an integrative narrative-discursive analysis. Results (a) contrapuntal style was gender-typically female; (b) monophonic style was gender-typically male; and (c) dissonant style was an important pathway to dual career discontinuation through which gender ideologies impacted the emergent adults with …

Anthocyanins: Biosynthesis, Distribution, Ecological Role, and Use of Biostimulants to Increase Their Content in Plant Foods—A Review

2021

In the past century, plant biostimulants have been increasingly used in agriculture as innovative and sustainable practice. Plant biostimulants have been mainly investigated as potential agents able to mitigate abiotic stress. However, few information is available about their ability to influence fruit quality or change fruit phytochemical composition. In particular, very little is known about their effects on anthocyanin synthesis and accumulation. Due to the increasing demand of consumers for healthier foods with high nutraceutical values, this review tries to fill the gap between anthocyanin content and biostimulant application. Here, we elucidate the chemical structure, biosynthetic pat…

Qualità dell’inclusione & inclusione di qualità. Monitoraggio e promozione della scuola inclusiva

2021

Attraverso l’intreccio costante tra teoria e prassi, il volume offre una poliedrica visione, in chiave pedagogica, dell’inclusione nelle sue dimensioni concettuali, semantica, normativa e qualitativa. L’inclusione come processo multifattoriale e in continuo divenire, si pone come occasione di crescita consapevole per l’intera comunità educante; per tali ragioni ha bisogno da una parte di una flessibilità misurativa e dall’altra di strumenti di valutazione facilmente utilizzabili dagli insegnanti, che aiutino ad accrescere la loro coscienza e la loro cognizione al fine di progettare piani di miglioramento organizzativo e culturale secondo una prospettiva inclusiva e democratica. Il volume si…

Improved centrifugal and hyperfine analysis of ND2H and NH2D and its application to the spectral line survey of L1544

2021

Abstract Quantifying molecular abundances of astrochemical species is a key step towards the understanding of the chemistry occurring in the interstellar medium. This process requires a profound knowledge of the molecular energy levels, including their structure resulting from weak interactions between nuclear spins and the molecular rotation. With the aim of increasing the quality of spectral line catalogs for the singly- and doubly-deuterated ammonia (NH2D and ND2H), we have revised their rotational spectra by observing many hyperfine-resolved lines and more accurate high-frequency transitions. The measurements have been performed in the submillimeter-wave region (265–1565 GHz) using a fr…

Analysis of dietary patterns and nutritional adequacy in lactating women : a multicentre European cohort (ATLAS study)

2021

Abstract Eating habits of lactating women can influence the nutrient composition of human milk, which in turn influences nutrient intake of breastfed infants. The aim of the present study was to identify food patterns and nutritional adequacy among lactating women in Europe. Data from a multicentre European longitudinal cohort (ATLAS study) were analysed to identify dietary patterns using cluster analysis. Dietary information from 180 lactating women was obtained using 3-d food diaries over the first 4 months of lactation. Four dietary patterns were identified: ‘vege-oils’, ‘fish-poultry’, ‘confectionery-salads’ and ‘mixed dishes’. Nutrition adequacy was not significantly different between …

Five-year follow-up results of aerobic and impact training on bone mineral density in early breast cancer patients

2021

Summary A 12-month exercise program reversibly prevented hip bone loss in premenopausal women with early breast cancer. The bone-protective effect was maintained for 2 years after the end of the program but was lost thereafter. Purpose Breast cancer survivors are at an increased risk for osteoporosis and fracture. This 5-year follow-up of a randomized impact exercise intervention trial evaluated the maintenance of training effects on bone among breast cancer patients. Methods Five hundred seventy-three early breast cancer patients aged 35–68 years and treated with adjuvant therapy were allocated into a 12-month exercise program or a control group. Four hundred forty-four patients (77%) were…

Differences in Symptomatology and Clinical Course of Acute Coronary Syndromes in Women ≤45 Years of Age Compared to Older Women

2021

Acute coronary syndromes (ACS) in young people are rare. The data regarding differences in symptoms in relation to age are scarce, which may have an influence on outcomes. The aim of this study was to evaluate the differences in the clinical course of ACS between younger women (≤45 years old) and older women (63-64 years old). We compared 7481 women with ACS from the Polish Registry of ACS between 2007 and 2014 (1834 women aged ≤45 years and 5647 women aged 63-64 years). The predominant symptom of ACS in both groups was chest pain, with a higher incidence occurring in younger women (90.4% vs 88.5%, P = 0.025). Prehospital cardiac arrest occurred more often in younger women (2.1% vs 0.8%, P0…

Prognostic factors on surgically and non-surgically treated oral squamous cell carcinoma: Advances in survival in fifteen years of follow up

2021

Background Retrospectively to evaluate the influence of radiochemotherapy (RCT) in the treatment of surgically and non-surgically treated Oral Squamous Cell Carcinoma (OSCC). Material and Methods We analysed 934 patients treated in Hospital Haroldo Juacaba (2000-2014; 15 years of study) by extraction of data type of cancer, localization of tumour, sex, age, race, education level, risk factors (smoking and alcohol use), year of diagnosis, TNM stage, therapeutic approach, health system used (public or private) and overall survival (OS). Surgically and non-surgically treated OSCC were compared by chi-square and Fisher's exact tests, and their prognostic factors were analysed by log-rank Mantel…