On the packing–holding flow in the injection molding of thermoplastic polymers

1988

Injection molding tests were performed on a Ny66 resin. Data of mass entering the mold during the packing–holding stage as a function of filling flow rate and holding time are presented. The experimental results are discussed on the basis of a simple model of the packing–holding stage. Only a small part of density increase due to crystallization seams to be compensated by the packing–holding extra flow.

Gene activity of polytene chromosomes in Drosophila species of the obscura group.

1988

The polytene chromosome puffing patterns of Drosophila guanche were established and compared with those of Drosophila subobscura. A total of 150 loci, active in some of the 17 developmental stages studied, were described and 23 of them were found to form the characteristic puffing pattern of D. guanche. Taking into account the number of puffs as well as the gene activity of each chromosome and the total gene activity, D. guanche seems to be less active than D. subobscura. Although both species show a degree of homology in their puffing patterns lower than that found for sibling species, the degree of homology is stronger than that between species belonging to the same group but to different…

Determination of mercury by cold‐vapour technique in several tissues of treated American red crayfish (Procambarus clarkii)

1988

Abstract Adult intermolt specimens of American red crayfish (Procambarus clarkii) collected from Lake Albufera (Valencia, Spain), were exposed to mercury during 96 h. The Hg‐concentrations used were 50, 100, and 250 μg Hg/1 as Cl2Hg. The content of mercury in muscle, midgut gland, antennal glands and gills was investigated. Determinations of mercury were made by cold‐vapour technique and AAS. The mercury levels in all examinated tissues increased significantly (ANOVA test, p < 0.01) with increasing Hg‐concentration in the water.

Presynaptic regulation of the electrically evoked release of endogenous dopamine from the isolated neurointermediate lobe or isolated neural lobe of …

1988

Isolated neurointermediate lobes (NILs) or isolated neural lobes (NLs) of the rat pituitary gland were incubated in Krebs-HEPES solution which contained pargyline and the dopamine uptake inhibitor GBR 12921. The release of endogenous dopamine was determined by HPLC with electrochemical detection. Electrical stimulation of the pituitary stalk induced a frequency-dependent release of dopamine. The release of dopamine from the combined NIL evoked by stimulation at 15 Hz was increased by 130% in the presence of the dopamine D2 receptor antagonist, (-)-sulpiride; the (+)-enantiomer of sulpiride had virtually no effect. When the stimulation frequency was 3 Hz (-)-sulpiride caused an increase in d…

Endogenous adenosine inhibits hippocampal CA1 neurones: further evidence from extra- and intracellular recording.

1988

Extracellular and intracellular recordings from CA1 pyramidal neurones of rats in vitro were used to study the effects of endogenous and exogenously applied adenosine. The adenosine receptor antagonist, caffeine, enhanced the intracellular recorded e.p.s.p.-i.p.s.p. sequence evoked by stimulation of the stratum radiatum which is antagonized by exogenous adenosine. The late, potassium dependent i.p.s.p. was not antagonized. The adenosine uptake inhibitor, nitrobenzylthioinosine (NBTI), mimicked the effects of exogenously applied adenosine. The effects of NBTI and of exogenously applied adenosine were antagonized by caffeine in the same manner. Exposure to adenosine deaminase enhanced the evo…

Flow field, swimming velocity and boundary layer: parameters which affect the stimulus for the lateral line organ in blind fish

1988

The data presented support the hypothesis that the flow field supplies the stimulus to the lateral line organ (LLO) in blind cave fish (Anoptichthys jordani). Two basic predictions from the theoretical analysis of the flow field were confirmed: (i) individual blind cave fish prefer particular swimming velocities, (ii) the velocity preferred depends on the cross-sectional area (CSA) of the fish, i.e. the smaller the CSA the higher the swimming velocity. This relationship was found also in experimentally blinded fish of other species. Furthermore, when placed in unfamiliar surroundings, blind cave fish swim at higher velocities than in familiar surroundings for a certain habituation period. T…

Exploring theoretical frameworks for the analysis of fertility fluctuations

1988

The Easterlin theory, popular during the 1970s, explained population fluctuations in terms of maximization of choice, based on the evaluation of previously acquired information. Fluctuations in procreational patterns were seen as responses to conflict between 2 consecutive generations in which the propensity to procreate is inversely related to cohort size. However, the number of demographic trends not directly explainable by the hypothesis imply that either the model must be extended over a longer time frame or that there has been a drastic change of regime, i.e., a basic change in popular attitudes which determine decision making behavior. 4 strategic principles underlie reproductive deci…

Reactions of α-diimino ligands with the chloro-bridged dimer [RhCl(COD)]2(COD=1,5-cyclooctadiene)

1988

Abstract The reactions of α-diimino ligands N - N ′ [ N - N ′= 2,2′-bipyridine (bipy), C 5 H 4 N2CHNR (R= C 6 H 4 OMe- p , PyCa), RNCHCHNR (R=C 6 H 4 - OMe- p , DAB)] with [RhCl(COD)] 2 give rise to stoichiometry, solvent, ligand, and temperature dependent equilibria. In general, the 1/1 ligand/dimer reaction yields the ionic product [Rh(COD)( N - N ′)] [RhCl 2 (COD)], at room temperature. For N - N ′=DAB, the ionic form is in equilibrium with the binuclear compound [{RhCl(COD)} (μ-DAB){RhCl(COD)}] (containing a σ σ,'- N , N ′ bridging α-diimine), which becomes the predominant species at low temperatures. In [Rh(COD)( N - N ′)] [RhCl 2 (COD)], a fast exchange of the Rh(COD) unit betwe…

Emergence phenology and ecology of aquatic and semi-terrestrial insects on a boreal raised bog in Central Finland

1988

Emergence of peatland insects was studied in Central Finland by sampling insects on a raised bog with tent traps from five different surfaces: muddy hollow without vegetation; hollow covered with Sphagnum; deep (0.7-0.9 m) open-water pool; shallow (about 0.3 m) pool with bottom covered by Carex vegetation; shallow (about 0.3 m) pool with bare muddy bottom. The material was collected at two-days intervals from 13 May until 31 August in 1981. Biomass emerging from the sites varied considerably. In general, aquatic sites were clearly more productive than semi-terrestrial sites. Corrected total biomass values for deep pools, shallow Carex pools, and shallow mud pools were 2.471, 1.066, and 0.51…

An X-ray scattering study of lipid monolayers at the air-water interface and on solid supports

1988

Abstract Monolayers of the lipid arachidic acid (C20) and of the phospholid dimyristolyphosphatidic acid (PMDA) have been studied by X-ray reflection and diffraction technique, using a purpose-built Langmuir trough installed at the sample stage of our high-resolution X-ray diffractometer at the DORIS synchroton X-ray source in Hamburg. For comparison we also report data for monolayers of C20 on a solid support using a 10 kW rotating anode X-ray source. By the X-ray reflection method, the density profile across the interface is probe, while in-plane diffraction measurements gauge the two-dimensional crystalline properties of the monolayers. Flourescence microscopy experiments of DMPA monolay…

Role of murine macrophages and complement in experimental campylobacter infection

1988

Summary. The roles of macrophages and the complement system as potential host defence mechanisms in mice against campylobacter infection were studied in vivo, by depleting the murine serum-complement or the phagocytic cells. Macrophage-depletion was performed by intraperitoneal (i.p.) injection of silica dust, Liquoid or dextran sulphate. During 5 days after infection, such mice showed a significant increase in mortality, compared with controls. In contrast, mice that were previously decomplemented by i.p. injection of Cobra Venom Factor showed no significant increase in mortality. The results with combined macrophage depletion and decomplementation did not differ from those with macrophage…

Electron Microscopic Studies of Spruce Needles in Connection with the Occurrence of Novel Forest Decline.

1988

Needles of four spruce trees showing different degrees of novel kinds of forest decline were investigated by electron microscopy. Green needles appearing at least superficially still intact were selected for the present investigation. Most of the mesophyll appeared to be undamaged. However, groups of atypical mesophyll cells were found close to the endodermis or the hypodermis. The chloroplasts of the apparently damaged cells were particularly affected. Changes in the matrix of the chloroplasts, i.e,. increased affinity to osmium, occurrence of extensive nests of plastoglobuli, as well as damage to the membranes, i.e. lesions in the envelope and abnormal thylakoid membranes, were observed. …

How hexoses and inhibitors influence the malate transport system in Zygosaccharomyces bailii

1988

When grown in fructose or glucose the cells of Zygosaccharomyces bailii were physiologically different. Only the glucose grown cells (glucose cells) possessed an additional transport system for glucose and malate. Experiments with transport mutants had lead to the assumption that malate and glucose were transported by one carrier, but further experiments proved the existence of two separate carrier systems. Glucose was taken up by carriers with high and low affinity. Malate was only transported by an uptake system and it was not liberated by starved malate-loaded cells, probably due to the low affinity of the intracellular anion to the carrier. The uptake of malate was inhibited by fructose…

Hepatic transferrin receptors in hereditary hemochromatosis.

1988

Color-Doppler Flow Mapping of the Heart in Normal Subjects

1988

Immunohistochemical evidence for the presence of peptides derived from proenkephalin, prodynorphin and proopiomelanocortin in the guinea pig pineal g…

1988

By using a plethora of region-specific antisera, this light microscopic immunohistochemical study revealed that derivatives from the three opioid precursors, i.e. proenkephalin, prodynorphin and proopiomelanocortin are differentially distributed in the pineal gland of guinea pig. Various molecular forms of immunoreactive opioid peptides derived from proenkephalin or prodynorphin were present in a minority of pinealocytes as well as in nerves. In contrast to this dual distribution pattern of opioid-active peptides, the opioid-inactive derivative from proopiomelanocortin, alpha-melanocyte stimulating hormone, was exclusively present in a large proportion of pinealocytes. A multiple and differ…

Laser Doppler flowmetry in subepidermal tumours and in normal skin of rats during localized ultrasound hyperthermia.

1988

Laser Doppler flowmetry has been applied to normal skin and to subepidermal tumours during localized ultrasound hyperthermia in the rat. In normal skin, 40 degrees C hyperthermia only induced a marginal increase in the red blood cell flux. Significant increases occurred after 20 min at 42 degrees C and after 4 min at 44 degrees C. During 44 degrees C hyperthermia maximum fluxes were reached after 24 min. Thereafter, the flow declined and finally approached preheating values. In contrast, in subepidermal tumours 40 degrees C hyperthermia on the average induced a slight decrease of the flux. During 42 degrees C hyperthermia a significant flow decrease was found after 40 min of heating. Follow…

Entanglement in polystyrene detected by translational diffusion of photo-labeled molecules

1988

Mesure des coefficients de diffusion de polystyrenes marques et comparaison avec une equation phenomenologique reliant la masse moleculaire critique entre les enchevetrements Mc a ces masses moleculaires respectives de la chaine diffusant et de la matrice. Comparaison avec les theories recentes

Lactate-induced inhibition of tumor cell proliferation.

1988

Abstract Culture medium that was recovered from tumor cell or fibroblast cultures during the plateau phase, and that was replenished by addition of glucose, glutamine, and serum and readjustment of pH had a distinct growth-inhibiting effect on monolayer cell cultures. The effect, which was not specific for a given cell strain, may be partially responsible for the "density inhibition" commonly observed in malignant cells grown in monolayer cultures. By modifying fresh growth media, it was shown that the growth inhibition observed can be partly attributed to the accumulation of lactate in the culture medium of plateau phase cells. This substance reduced the plating efficiency and the number o…

Model independent determination of GEn from the reaction

1988

Abstract Electrodisintegration of vector polarized deuterium by longitudinally polarized electrons offers a possibility for measuring the neutron electric form factor G En . In principle, the electron asymmetry is essentially proportional to G En when quasi-free kinematics are employed. We investigate the model dependence of this result by employing several NN force models both with and without meson-exchange and isobar corrections. We find the asymmetry to be remarkably model independent near the neutron quasi-elastic peak.

Interleukin 1 stimulates T lymphocytes to produce granulocyte-monocyte colony-stimulating factor.

1988

T lymphocytes are thought to cooperatively interact with monocytes to produce colony-stimulating factors (CSF). However, little is known about monocyte-mediated signals leading to CSF-secretion by T lymphocytes, although soluble monocyte products have been implicated. We have employed monoclonal antibody anti-T3B covalently coupled to CnBr-activated Sepharose 4B beads, to show that multimeric ligation of T cell antigen receptor leads to T cell receptiveness to interleukin 1 (IL-1), as indicated by T cell production of CSF, which induces growth of myeloid progenitor cells into neutrophil, eosinophil, and monocyte colonies. To investigate the molecular basis of these findings, total RNA was e…

Airway Responsiveness to Histamine in Patients Refractory to Repeated Exercise

1988

To investigate the mechanisms contributing to refractoriness in exercise-induced asthma (EIA), airway responsiveness to histamine was studied in eight asthmatic patients. Patients were included in the study on the basis of their refractory response to multiple exercise challenges. Incremental challenges with inhaled histamine were performed at rest and 40 minutes after single and paired exercise tests. The geometric mean histamine concentration required to produce a 20 percent fall in FEV1 (PC20) for the challenge after paired exercise test (4.34 mg/ml) was significantly higher (p greater than 0.001) than those for the challenges after a single exercise (1.05 mg/ml) and for the challenge at…

Nonstandard analysis in classical physics and quantum formal scattering

1988

After a rigorous introduction to hyperreal numbers, we give in terms of non standard analysis, (1) a Lagrangian statement of classical physics, and (2) a statement of formal quantum scattering. © 1988 Plenum Publishing Corporation.

Investigation on the Nitrogen Metabolism of Spruce Needles in Relation to the Occurrence of Novel Forest Decline

1988

Summary In order to obtain information on the nitrogen metabolism of undamaged and damaged spruce ( Picea abies ), investigations were performed in 1985 and 1986 on the activity of glutamine synthetase and on the content of free ammonium and soluble proteins in spruce needles. In addition, the chlorophyll content was determined. Needles from the second needle year and the seventh whorl were used. The investigations were carried out in pair comparison on a 20-year-old spruce plantation and in comparison with damage classes on an 80-year-old spruce plantation. Both the pair comparison and the contrasting of different damage groups show an unequivocal decrease of the chlorophyll content correl…

15 Thesen zur aktuellen Situation der myofunktionellen Therapie

1988

Reactions of electron-rich heterocycles with orthocarboxylic acid derivatives.11. Reactions of carbazole and 4-methoxycarbazole with triethyl orthofo…

1988

Carbazole (1a) and 4-methoxycarbazole (1b) can be regioselectively functionalized by reaction with triethyl orthoformate. Whereas the reaction of 1a with the ortho ester furnishes the amide acetal 2, the new carbazole derivatives 4–10 are formed, depending on the reaction conditions, in the electrophilic substitution of 1b. The products of this reaction sequence provide a contribution to studies on the mechanism of the transformation of 1b to tris-carbazolylmethane 5. Compound 5 represents a new, three-bladed propeller in the triheteroarylmethane series.

Influence of pump coherence on the dynamic behavior of a laser

1988

The dynamic behavior of a coherently pumped single-mode unidirectional ring laser with a homogeneously broadened three-level active medium is studied. Our formulation is based on a set often real equations of the plane-wave, mean-field Maxwell–Bloch type. The instability domain in the main control parameters space is determined. Our numerical study of these equations for a parameter range of the type explored in the recent experiments by Weiss Brock [ Phys. Rev. Lett.57, 2804 ( 1986)] reveals some similarities, but striking differences between our theoretical predictions and their experimental observations are also noted.

Characterization of R-plasmids in environmental isolates ofsalmonella: Host range and stability

1988

Four environmental isolates ofSalmonella, resistant to several drugs, were examined for plasmid carriage with four different plasmid DNA isolation procedures. The method of Birnboim and Doly gave the best results. Three of the strains possessed a single plasmid with molecular weights of 60 (kanamycin resistant), 44.5 (kanamcin resistant), and 23.4 Md (ampicillin and amoxicillin resistant); the other strain (resistant to tetracycline) harbored two plasmids of 69.8 and 2.2 Md. The 69.8 Md was the one responsible for resistance. All plasmids were fi−, and the 44.5 Md Kcr plasmid synthesized a sex pilus type F. Some properties related to the dissemination of R-plasmids, such as host range, tran…

Solute-induced Water Structure: Computer Simulation on a Model System

1988

Abstract Two series of Monte Carlo simulations have been carried out on a system consisting of 125 water molecules, one of which is kept fixed to simulate a water molecule whose mobility is restricted by a solute. The results are checked against similar simulations without restrictions, used as a control, and they show how the blocked molecule helps increase both the structural order and the connectivity of the hydrogen bond network. Cooperativity originating from proton polarizability of H-bonds and/or from many-body terms of interaction potentials cannot be involved since we use a rigid water model and ab initio pair potentials. The present findings are interpreted as indicative of a moti…

Hβ photometry for UVBY standard stars

1988

From 1984 to 1986 the authors made several observational campaigns at Calar Alto and La Palma Observatories using the uvby and β photometric systems to monitor a selected sample of late-type variable stars. In this paper they present the β values for 38 uvby standard stars to contribute to the uvby-β calibration works on late-type stars. In the final discussion, the β computed values are plotted against the Stroemgren b-y, m_(1), and c_(1) indices.

L'insertion professionnelle : plus de chômage, moins d'emploi pour les filles

1988

On the use of a metric-space search algorithm (AESA) for fast DTW-based recognition of isolated words

1988

The approximating and eliminating search algorithm (AESA) presented was recently introduced for finding nearest neighbors in metric spaces. Although the AESA was originally developed for reducing the time complexity of dynamic time-warping isolated word recognition (DTW-IWR), only rather limited experiments had been previously carried out to check its performance in this task. A set of experiments aimed at filling this gap is reported. The main results show that the important features reflected in previous simulation experiments are also true for real speech samples. With single-speaker dictionaries of up to 200 words, and for most of the different speech parameterizations, local metrics, a…

Espace et conflit : le choix des investissements dans des régions à risques

1988

Dans le classement et le choix des investissements, les risques dans l'espace doivent être ajoutés à l'incertitude du futur dans le cadre d'un calcul économique élargi. Cette approche permet de définir des critères pour évaluer les méthodes pratiques d'estimation des risques régionaux.

Fabrication and characterization of tuned Gaussian mirrors for the visible and the near infrared

1988

A thin-film technique has been developed for vacuum fabrication of mirrors with Gaussian reflectivity profiles. Samples with diameters from 2 to 8 mm and assigned maximum reflectivities for visible or near-IR wavelengths have been made and their optical properties evaluated. By properly choosing both the geometry of the evaporation source and the masking system, one can obtain quasi-Gaussian or super-Gaussian reflectivity profiles.

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1988

Introduction into the study of translational diffusion by laser techniques

1988

Breve description de la technique du reseau holographique pour mesurer les coefficients de diffusion de traceurs dans des polymeres et de la technique de spectrometrie de correlation de photon pour la mesure des coefficients de diffusions mutuelle dans des melanges de polymeres