Females’ customer engagement with eco-friendly restaurants in Instagram: the role of past visits

2022

Purpose The purpose of this study is to examine the effect on the customer brand engagement (CBE) of followers of an eco-friendly restaurant of their perceptions of the originality of the firm-generated content posted online by the restaurant and the effect of CBE on brand advocacy and behavioural intentions to visit the restaurant, paying special attention to the moderating role of past visits to the restaurant. Design/methodology/approach The hypotheses were tested using structural equation modelling with a sample of 491 female Instagram users who follow the online account of a particular eco-friendly dining establishment. Two group comparisons were conducted to test the moderating effec…

Proof-of-Principle Direct Measurement of Particle Statistical Phase

2022

The symmetrization postulate in quantum mechanics is formally reflected in the appearance of an exchange phase governing the symmetry of identical-particle global states under particle swapping. Many indirect measurements of this fundamental phase have been reported thus far, but a direct observation has been achieved only recently for photons. Here, we propose a general scheme capable of directly measuring the exchange phase of any type of particle (bosons, fermions, or anyons), exploiting the operational framework of spatially localized operations and classical communication. We experimentally implement it on an all-optical platform, providing a proof of principle for different simulated …

Naisten asiantuntemuksen saaminen näkyviin vaatii konkreettisia tekoja

2022

Pääkirjoitus 4/2023

Ultrasound-Guided Infraclavicular Axillary Vein Versus Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients: A Random…

2022

OBJECTIVES: This clinical trial aimed to compare the ultrasound-guided in-plane infraclavicular cannulation of the axillary vein (AXV) and the ultrasound-guided out-of-plane cannulation of the internal jugular vein (IJV). DESIGN: A prospective, single-blinded, open label, parallel-group, randomized trial. SETTING: Two university-affiliated ICUs in Poland (Opole and Lublin). PATIENTS: Mechanically ventilated intensive care patients with clinical indications for central venous line placement. INTERVENTIONS: Patients were randomly assigned into two groups: the IJV group (n = 304) and AXV group (n = 306). The primary outcome was to compare the IJV group and AXV group through the venipuncture an…

Simeizas teleskopa montāžas gaita Friča Blumbaha fotogrāfijās

2022

Latvijas Universitātes Muzeja F. Candera un Latvijas astronomijas kolekcijas krājumā atrodas latviešu astronoma un metrologa Friča Blumbaha (1864 – 1949) 23 uzņemtās fotoplates un 3 papīra fotogrāfijas, kas atspoguļo viņa līdzdalību Simeizas viena metra teleskopa tapšanā 1922. - 1925. gadā. Tajās redzams F. Blumbahs, teleskopa izgatavotājfirmas Grubb Telescope Company darbinieki un Krievijas pārstāvji, kas bija iesaistīti pasūtījuma veikšanā. Attēlos labi redzamas atsevišķas teleskopa daļas, galvenais spogulis un teleskopa kupols. Tekstā aprakstīta Simeizas teleskopa pasūtīšana, izgatavošana, izmantošana Simeizā un teleskopa bojāeja Otrā pasaules kara laikā.

Anders Wilhelm Ingman – kiistanalainen raamatunkääntäjä

2022

Eric Hobsbawm, Äärimmäisyyksien aika (1914–1991) ja Risto Alapuro, Vallankumouksessa. Moskovan päiväkirjat 1990–1991

2022

PHOTOGRAMMETRY NOW AND THEN - FROM HAND-CRAFTED TO DEEP-LEARNING TIE POINTS

2022

Abstract. Historical images provide a valuable source of information exploited by several kinds of applications, such as the monitoring of cities and territories, the reconstruction of destroyed buildings, and are increasingly being shared for cultural promotion projects through virtual reality or augmented reality applications. Finding reliable and accurate matches between historical and present images is a fundamental step for such tasks since they require to co-register the present 3D scene with the past one. Classical image matching solutions are sensitive to strong radiometric variations within the images, which are particularly relevant in these multi-temporal contexts due to differen…

Development of Neural Network Prediction Models for the Energy Producibility of a Parabolic Dish: A Comparison with the Analytical Approach

2022

Solar energy is one of the most widely exploited renewable/sustainable resources for electricity generation, with photovoltaic and concentrating solar power technologies at the forefront of research. This study focuses on the development of a neural network prediction model aimed at assessing the energy producibility of dish–Stirling systems, testing the methodology and offering a useful tool to support the design and sizing phases of the system at different installation sites. Employing the open-source platform TensorFlow, two different classes of feedforward neural networks were developed and validated (multilayer perceptron and radial basis function). The absolute novelty of this approac…

Transcription regulators and ultra-rare and other rare translocation-related sarcomas treated with trabectedin: A proof of principle from a post-hoc …

2022

BackgroundAmong sarcomas, which are rare cancers with an incidence of <6 per 100.000/year cases, ultra-rare sarcomas have an incidence of approximately ≤1/1,000,000/year cases and altogether account for ~20% of all soft tissue sarcomas (STS) and bone sarcomas. The Italian Sarcoma Group has recently performed a non-interventional, retrospective TrObs study with data from 512 anthracycline-pretreated patients with advanced multiple STS histologies and treated with trabectedin (Palmerini, Cancers 2021; ClinicalTrials.gov Identifier: NCT02793050).MethodsA post-hoc analysis of case series to evaluate the efficacy and safety of trabectedin on patients with ultra-rare and other rare translo…

Supplementary material 1 from: Galasso G, Domina G, Andreatta S, Argenti C, Astuti G, Bacaro G, Bacchetta G, Bagella S, Banfi E, Barberis D, Bartoluc…

2022

Supplementary data

Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis

2022

Abstract Objective Gut fibrosis occurs under chronic inflammation. This study examined the effects of different cyclooxygenase (COX) inhibitors on fibrosis in the inflamed colon. Methods Colitis was induced by 2,4-dinitrobenzenesulfonic acid (DNBS) in albino male Sprague–Dawley rats. After 6, 12 and 18 days, macroscopic and microscopic damage, collagen and elastic fibre content were examined. At day 6, pro-fibrotic factors (collagen I and III, hydroxyproline, fibronectin, matrix metalloproteinase-2 and -9), transforming growth factor-beta (TGF-β) signalling [TGF-β, Ras homolog gene family member A (RhoA), phosphorylated small mother against decapentaplegic (pSMAD)-2 and -6] and peristalsis …

Special Issue on Structural and Thermo-Mechanical Analyses in Nuclear Fusion Reactors

2022

Nuclear fusion is one of the most promising technologies to be adopted for the production of electricity [...]

The Therapeutic Role of SGLT-2 Inhibitors in Acute Heart Failure: From Pathophysiologic Mechanisms to Clinical Evidence with Pooled Analysis of Relev…

2022

(1) Background: Sodium-glucose co-transporter-2 (SGLT-2) inhibitors constitute a novel drug class with remarkable cardiovascular benefits for patients with chronic heart failure (HF). Recently, this class has been utilized in acute HF as an additional treatment option to classic diuretics, which remain the cornerstone of treatment. (2) Methods: We attempted to identify those pathophysiologic mechanisms targeted by SGLT-2 inhibitors, which could be of benefit to patients with acute HF. We then conducted a comprehensive review of the literature within the PubMed database in order to identify relevant studies, both randomized controlled trials (RCTs) and observational studies, assessing the sa…

Staff Members’ Professional Agency within the Staff Community and the Education Policies: Supporting Integration in Multicultural and Multiling…

2022

In recent decades, increased diversity and migration have challenged school staff members’ ways of working. This study aimed to identify the challenges faced by Finnish school staff in supporting students with migrant backgrounds, and to elaborate on how they enact professional agency toward these challenges. The data consist of 15 thematic interviews with staff members across various work positions in two Finnish lower secondary schools. Based on thematic analysis, the challenges within the staff community and the education policies were found to include the following: (1) the diversification of students makes tensions more visible in the staff community, and (2) inflexible education polic…

Biogeographic Anomalies in Shore Flies as Revealed in Revision of the Shore-Fly Genus Subpelignus Papp (Diptera: Ephydridae)

2022

Subpelignus Papp is revised, including description of (1) a new species, S. gagnei Zatwarnicki and Mathis (New Zealand. North Island. ND: Whananaki South (35°31.1'S, 174°27.2'E); (2) two new combinations, Subpelignus antennalis (Aldrich, 1931) and Subpelignus limosinus (Becker, 1896); (3) a new synonym, S. hortobagensis Papp, 1983 = S. limosinus Becker; and (4) description of a new subgenus, Niratissa Zatwarnicki and Mathis, for S. maculipennis Mathis and Zatwarnicki. Descriptions of revised and the newly described species include some of the first illustrations of structures of the male terminalia. Detailed locality data for all species examined are provided. For perspective and to facilit…

Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex

2022

Aiming at reducing the unselective cytotoxicity of Pt(II) chemotherapeutics, a great deal of effort has been concentrated into the design of metal-containing drugs with different anticancer mechanisms of action. Inert Pt(IV) prodrugs have been proposed to be a valid alternative as they are activated by reduction directly into the cell releasing active Pt(II) species. On the other hand, a promising strategy for designing metallodrugs is to explore new potential biological targets rather than canonical B-DNA. G-quadruplex nucleic acid, obtained by self-assembly of guanine-rich nucleic acid sequences, has recently been considered an attractive target for anticancer drug design. Therefore, comp…

Examining the Indirect Effect of Online Gaming on Depression via Sleep Inequality and Anxiety—A Serial and Parallel Mediation Analysis

2022

Stress-related disorders are highly prevalent among first-year college students. Gaming disorder (GD) is an emerging disorder linked to physical and psychological consequences. We aimed to investigate the mechanism linking GD with anxiety, depression, and sleep disorders among first-year undergraduate students. Four hundred fifty-seven participants were recruited, and the survey included the Internet Gaming Disorder Scale Short-Form (IGDS9-SF), Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), and Pittsburgh Sleep Quality Index (PSQI). Our results showed that female students scored significantly higher than males in anxiety and depression. Furthermore, we found…

Notulae to the Italian native vascular flora: 14

2022

In this contribution, new data concerning the distribution of native vascular flora in Italy are presented. It includes new records, confirmations, and status changes to the Italian administrative regions. Nomenclatural and distribution updates, published elsewhere, and corrigenda are provided as Suppl. material 1.

Rate of hospitalizations and mortality of Respiratory Syncytial Virus infection compared to influenza in older people: a systematic review and meta-a…

2022

Respiratory Syncytial Virus (RSV) is commonly regarded as an infection typical of children, but increasing literature is showing its importance in older people. Since the data regarding the impact of RSV are still limited for older people, the aim of this systematic review and meta-analysis is to compare the rate of hospitalization and mortality between RSV and influenza in this population. A systematic literature search until 15 June 2022 was done across several databases and including studies reporting incidence rate and cumulative incidence of hospitalization and mortality in RSV and influenza affecting older people. Among 2295 records initially screened, 16 studies including 762,084 old…

Information Integration, Coordination Failures, and Quality of Prescribing

2022

Poor information flows hamper coordination, potentially leading to suboptimal decisions in health care. We examine the effects of a large-scale policy of health information integration. We use the staggered adoption of a nationwide electronic prescribing system over four years in Finland and prescription-level administrative data. Our results show no discernible effect on the probability of co-prescribing harmful drugs on average, but the heterogeneity analysis reveals that this probability reduces in rural regions, by 35 percent. This substantial reduction is driven by interacting prescriptions from different physicians and generalists. Information integration can therefore improve the coo…

Fratricidio y rebelión en los dramas del Sturm und Drang : Leisewitz, Klinger y los hermanos enfrentados

2022

El presente artículo se propone analizar las obras Julius von Tarent de Johann Anton Leisewitz y Die Zwillinge de Friedrich Maximilian Klinger, ambos publicados en 1776 y exponentes del drama del Sturm und Drang. En estos análisis se estudiarán las motivaciones de los personajes, así como las reinterpretaciones que cada obra ofrece del fratricidio de Caín y Abel: en Leisewitz, Julius no puede unir las esferas de la razón de Estado y del amor, con lo que decide rebelarse contra la primera e intentar huir, pero Guido se lo impide y termina asesinándolo; en Klinger, Guelfo cuestiona la primogenitura de Ferdinando y la reclama para sí, pues considera que se la han robado y le han dado todo a su…

Light and Divine Wisdom: An Alternative Interpretation of the Iconography of the Fuller Brooch

2022

La spilla di Fuller viene considerata una rappresentazione, in ambito inglese, dei cinque sensi. Si ritiene che il personaggio centrale, che rappresenta la vista, presenti anche uno o più significati figurativi, legati a idee e concetti che erano correnti nel contesto culturale di re Alfredo. Questi significati figurativi dovevano presumibilmente essere enfatizzati e chiariti dai due oggetti che questa figura regge. Finora, tuttavia, questi oggetti non sono stati interpretati in modo soddisfacente, anche se la maggior parte degli studiosi ritiene che essi possano rappresentare delle piante o cornucopie. Il presente studio esplora l'ipotesi che questi oggetti siano in realtà delle torce, att…

Correlation between Anthropometric and Ultrasound Measurement for Dry Needling of The Iliocostalis Lumborum Muscle with a Safety Protocol: A Cross-Se…

2022

Introduction: the management of musculoskeletal pain through the application of dry needling (DN) is effective. The application of this technique can carry very infrequent major risks on muscles, such as on the iliocostalis lumborum due to its proximity to the kidney and the peritoneum. It is important to establish a DN protocol based on the different anthropometric variables of the subjects. Main objective: the main objective of this study was to investigate the correlation between different anthropometric variables and the skin-kidney and skin-peritoneum distances to establish the size of the needle that could perform DN in the iliocostalis lumborum muscle without risk. Design: a cross-se…

Medición para el cambio en entidades sociales: La elaboración de un Cuadro de Mando Integral

2022

Los cambios sociales y las demandas actuales evidencian la necesidad de que las organizaciones de la economía social setransformen con agilidad y con visión de futuro. Para lograrloy avanzar en el cumplimiento de los ODS, resulta clave el establecimiento de metas estratégicas y la medición de resultados. En este trabajo, se presenta el proceso de la construcción e implementación de un Cuadro de Mando Integral como herramienta de gestión y estrategia de acción social en la Federación Española de Fibrosis Quística, entidad sin ánimo de lucro del Tercer Sector de Acción Social. Se ha utilizado el método Delphi como herramienta de consenso, contando con la participación de catorce expertos con …

Distribution of KIR Genes and Their HLA Ligands in Different Viral Infectious Diseases: Frequency Study in Sicilian Population

2022

Natural killer (NK) cells play a role in defence against viral infections by killing infected cells or by producing cytokines and interacting with adaptive immune cells. Killer immunoglobulin-like receptors (KIRs) regulate the activation of NK cells through their interaction with human leucocyte antigens (HLA). Ninety-six Sicilian patients positive to Human Immunodeficiency Virus-1 (HIV) and ninety-two Sicilian patients positive to SARS-CoV-2 were genotyped for KIRs and their HLA ligands. We also included fifty-six Sicilian patients with chronic hepatitis B (CHB) already recruited in our previous study. The aim of this study was to compare the distribution of KIR–HLA genes/groups of these t…

Mutations along human chromosomes: How randomly scattered are they?

2022

The diversity of mutations in human chromosomes is nowadays very well documented. The mutations characterize populations in the world as well as genetic causes of diseases. In the approach that we follow, we study the patterns of gaps between mutations by means of the rescaled range analysis and the fractal dimension estimates. The results for chromosomes 1 to 22 and X indicate the existence of the so-called Hurst phenomenon in all of them. The interpretation of this outcome entails the presence of long-range correlations and we propose an explanation based on the genomic feature dubbed linkage disequilibrium, a nonrandom association of alleles at different loci. An unexpected outcome is th…

Osservatorio della Pesca del Mediterraneo - Rapporto Annuale Pesca e Acquacoltura 2022

2022

Impact of Endocrine Disorders on IVF Outcomes: Results from a Large, Single-Centre, Prospective Study

2022

Abstract Endocrine disorders negatively influence the ovarian function, and increasing incidence of endocrine diseases with age may have further negative effects on pregnancy rate. Prospective cohort study of 231 consecutively enrolled patients underwent IVF treatment. In patients with known endocrine disorders, the laboratory parameters were corrected before IVF treatment. One hundred sixty one patients (69.7%) had at least one known and treated endocrine disorder (study group), and 70 patients were endocrine negative (control group). Endocrine disorders diagnosed were thyroid disorders (32.5%), diminished ovarian reserve (23.8%), insulin resistance (22.5%), PCOS (15.2%), hyperprolactinaem…

Comorbidities and clinical outcomes of a lung cancer screening trial participants with chronic obstructive pulmonary disease in three-year follow-up

2022

To improve the effectiveness of lung cancer screening using low-dose computed tomography (LDCT), the presence of smoking-related comorbidities that may significantly affect mortality in this group should be taken into account. Material and methods: A questionnaire survey and spirometry tests were conducted in a group of 730 respondents as part of a lung cancer screening study between 2016 and 2018. People diagnosed with COPD underwent a three-year follow-up to assess the incidence of medical events. Results: Our study confirmed that cardiovascular diseases (CVDs) were the most common comorbidities in patients who were diagnosed with COPD and participated in LDCT lung cancer screening. Among…

Effects of exposure to a glyphosate-based herbicide on haematological parameters, plasma biochemical indices and the microstructure of selected organ…

2022

Contamination of water environments with herbicides is a common problem nowadays. The aim of the current study was to evaluate the effects of Roundup on common carp ( Cyprinus carpio) after 1, 3 and 10 days of exposure. The used concentrations corresponded to 1 and 5 mg/l of the active ingredient (glyphosate potassium salt). The haematological analysis performed showed a decrease of the RBC count, as well as an increase of the other erythrocyte indices (Hb, MCV, MCH, MCHC). Most of these changes were dependent on the concentration and time. An increase of the WBC count and the percentage of immature neutrophils occurred, thus indicating the presence of inflammation. In the studied blood bio…

Polarized radio emission unveils the structure of the pre-supernova circumstellar magnetic field and the radio emission in SN1987A

2022

The detected polarized radio emission from remnant of SN1987A opens the possibility to unveil the structure of the pre-supernova magnetic field in the circumstellar medium. Properties derived from direct measurements would be of importance for understanding the progenitor stars and their magnetic fields. As the first step to this goal, we adopted the hydrodynamic data from an elaborated three-dimensional (3-D) numerical model of SN1987A. We have developed an approximate method for `reconstruction' of 3-D magnetic field structure inside supernova remnant on the `hydrodynamic background'. This method uses the distribution of the magnetic field around the progenitor as the initial condition. W…

Goût de France/Good France, un menu « à la française »

2022

Six semaines avant le colloque tourangeau « Modèle culinaire français : diffusion, adaptations, transformations, oppositions à travers le monde », soit le 22 octobre 2014, Laurent Fabius, alors ministre des Affaires étrangères et du Développement international, annonce devant le Conseil pour la promotion du tourisme – qu’il préside – le lancement de la campagne « Goût de France/Good France ». Alain Ducasse, parrain de l’opération 2015, accompagné d’autres chefs présents, apporta ensuite les a...

Clinical Potential of Circulating Cell-Free DNA (cfDNA) for Longitudinally Monitoring Clinical Outcomes in the First-Line Setting of Non-Small-Cell L…

2022

Background: Despite the increasing implementation of targeted and immunotherapy-based treatments, the prognosis of patients with advanced NSCLC remains dismal. We prospectively evaluated longitudinal plasma cfDNA kinetics as an early marker of therapeutic efficacy in patients with advanced NSCLC undergoing standard first-line treatments. Methods: From February 2020 to May 2022, treatment-naïve patients with advanced NSCLC were consecutively enrolled at the Medical Oncology Unit of the Paolo Giaccone University Hospital, Palermo (Italy). We quantified cfDNA in terms of ng/μL using a QubitTM dsDNA HS Assay Kit. The agreement between the cfDNA and radiologic response was evaluated from…

Local methods for complex spatio-temporal point processes

2022

La formazione degli insegnanti della scuola secondaria di secondo grado per orientare gli studenti alla scelta formativo-professionale post-diploma

2022

I professionisti dell’orientamento non sono gli unici attori chiamati a intervenire nei processi decisionali delle persone più giovani: gli insegnanti, proprio perché sono quotidianamente in contatto diretto con gli alunni in classe, possono intervenire in loro favore aiutandoli nel delicato processo di sviluppo personale e professionale. Per questo motivo è descritto inizialmente il quadro teorico della didattica orientativa, (l’orientare insegnando), per poi enunciare subito dopo le esigenze formative specifiche di un insegnante che voglia realizzare in classe la dimensione orientativa dell’attività docente. L’insegnante che vuole orientare i suoi alunni ha bisogno sia di una formazione t…