showing 36 of ~574560 from 574555 documents
Nonlinear optical properties of CH3NH3PbX3 CsPbX3 (X=Br,I) perovskites
2021
Longitudinal associations between parental and offspring's leisure-time physical activity: The Young Finns Study.
2021
Purpose The longitudinal influence of parental leisure-time physical activity (LTPA) on their offspring's LTPA is poorly understood. This study examined the longitudinal associations between parental LTPA and offspring's LTPA at two-time intervals. Method Child (offspring) participants (N=3596) were enrolled from the Cardiovascular Risk in Young Finns Study in 1980. Their LTPA was self-rated through nine phases from baseline to 2018 and categorized by year into youth (1980-1986) and adult (1992-2018) LTPA. Parental LTPA was assessed with a single self-reported question at three phases from 1980 to 1986. Latent growth curve modeling stratified by gender was fitted to estimate the potential p…
Sustainability reports and management control : Literature review and case study at Air France
2021
International audience
Evaluating the Efficiency of Water Distribution Network Sectors Using the DEA-Weight Russell Directional Distance Model: The Case of the City of Vale…
2021
In many cities, sectorization projects of the drinking water distribution network have been implemented. This study provides a methodology to evaluate the efficiency of the sectors of a water distribution network by applying a data envelopment analysis weighted Russell directional distance (DEA-WRDD) model. This non-radial DEA model gives the overall efficiency of each unit of analysis, as well as each input, output, and undesirable output considered in the evaluation. The variables used in the analysis provide a multidisciplinary view: economic factors (covering costs), water quality parameters, and technical aspects. The empirical analysis was performed for the sectors of the water distri…
Improvement of Biomass Gasification/Combustion Characteristics by Microwave Pretreatment of Biomass Pellets
2021
Printing Biology: engineering analytical platforms by molecular inks
2021
Co-Infections by Fusarium circinatum and Phytophthora spp. on Pinus radiata: Complex Phenotypic and Molecular Interactions
2021
13 Pág. Instituto de Ciencias Forestales (ICIFOR)
Préparation distancielle au CAPEPS externe : un objectif commun, des expériences différentes
2021
International audience
Le savoir mis en circulation dans l’entretien-conseil : étude de cas d’un tuteur EPS
2021
International audience
Considerazioni sull’ammissibilità delle leggi- provvedimento: il caso del finanziamento del Teatro Eliseo al vaglio della Corte costituzionale
2021
This paper examins the admissibility of so-called “leggi-provvedimento”, taking the cue from the effect of the national legislative provision, which recognizes eight million euro for biennium 2017-2018 to the Roman Teatro Eliseo, and which was recently submitted to the Italian Constitutional Court. This essay examins the responsibility of national legislature for adopting damaging legislative measure.
Muistisairaiden ja puoliso-omaishoitajien kokemuksia tuen riittämättömyydestä
2021
Muistisairautta sairastavien ikääntyneiden kotona asuminen onnistuu usein omaishoitajien avulla, mutta tukea tarvitaan myös sosiaali- ja terveyspalveluista. Aina kaikki eivät kuitenkaan saa riittävää apua ja tukea. Niin muistisairautta sairastavat ihmiset kuin omaishoitajatkin voivat kärsiä avun riittämättömyydestä. Tässä artikkelissa tutkimme, millaista tukea muistisairaat ja heidän puolisonsa kaipaavat ja millaisia kokemuksia heillä on avun riittämättömyydestä. Tutkimuksemme mukaan muistisairautta sairastavien ikääntyneiden ja omaishoitajien kohtaama avun riittämättömyys liittyy sekä palvelujärjestelmään ja erilaisiin tukimuotoihin että henkisen tuen tarpeisiin. Muistisairautta sairastava…
Increased Adiposity Appraised with CUN-BAE Is Highly Predictive of Incident Hypertension. The SUN Project
2021
Overweight and obesity are growing worldwide and strongly associated with hypertension. The Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index is proposed as an optimal indicator of body fatness. We aimed to investigate the association of body fat as captured by the CUN-BAE index with incident hypertension in a Mediterranean population. We assessed 15,950 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (63.7% women) initially free of hypertension. Participants completed follow-up questionnaires biennially. A validated 136-item food-frequency questionnaire was administered at baseline. We used Cox models adjusted for multiple confounders. …
Molecular mechanisms of endomembrane trafficking in plants
2021
Abstract Endomembrane trafficking is essential for all eukaryotic cells. The best-characterized membrane trafficking organelles include the endoplasmic reticulum (ER), Golgi apparatus, early and recycling endosomes, multivesicular body, or late endosome, lysosome/vacuole, and plasma membrane. Although historically plants have given rise to cell biology, our understanding of membrane trafficking has mainly been shaped by the much more studied mammalian and yeast models. Whereas organelles and major protein families that regulate endomembrane trafficking are largely conserved across all eukaryotes, exciting variations are emerging from advances in plant cell biology research. In this review, …
Introduction: Ernest Nagel and the Making of Philosophy of Science a Profession
2021
This chapter provides an overview of the life (Sect. 1.1) and philosophy (Sect. 1.2) of Ernest Nagel, as well as a summary of the chapters in this volume (Sect. 1.3). Regarding Nagel's philosophy, we focus on his role and activities to stabilize analytic philosophy (of science) and make it a profession, his views about the role and nature of history and sociology of science, naturalism, and socially engaged philosophy, and finally his understanding of the relation between science, society, and philosophy.
Magneli-type tungsten oxide nanorods as catalysts for the selective oxidation of organic sulfides
2021
Selective oxidation of thioethers is an important reaction to obtain sulfoxides as synthetic intermediates for applications in the chemical industry, medicinal chemistry and biology or the destruction of warfare agents. The reduced Magneli-type tungsten oxide WO3−x possesses a unique oxidase-like activity which facilitates the oxidation of thioethers to the corresponding sulfoxides. More than 90% of the model system methylphenylsulfide could be converted to the sulfoxide with a selectivity of 98% at room temperature within 30 minutes, whereas oxidation to the corresponding sulfone was on a time scale of days. The concentration of the catalyst had a significant impact on the reaction rate. R…
Job demands and psychological well-being among Gabonese civil servants: The mediating role of perceived organizational support
2021
The working conditions observed in public administration organizations have deleterious effects on the psychological well-being of employees. Professional resources can predict the relationship bet...
false
2021
Introduction Since 2009, multiple randomized trials have shown faster and deeper responses in CML patients treated with new-generation TKI (NG-TKI) compared to those treated with imatinib (IM). Are the same results observed in the general population? Materials and methods Patients were identified from the three French hematological malignancies population-based registries. All CML patients (ICD-O-3: 9875/3) diagnosed between 2006 and 2016 and resided in registries areas were included. The TKI generation effect on achievement of MMR in first-line therapy was assessed through a multivariate competitive risk analysis. An alluvial plot described the pathways leading to death. Results In total, …
Kohti jälkifossiilista työtä
2021
Anodic Dehydrogenative Cyanamidation of Thioethers: Simple and Sustainable Synthesis of N‐Cyanosulfilimines
2021
Abstract A novel and very simple to perform electrochemical approach for the synthesis of several N‐cyanosulfilimines in good to excellent yields was established. This method provides access to biologically relevant sulfoximines by consecutive oxidation using electro‐generated periodate. This route can be easily scaled‐up to gram quantities. The S,N coupling is carried out at an inexpensive carbon anode by direct oxidation of sulfide. Therefore, the designed process is atom economic and represents a new “green route” for the synthesis of sulfilimines and sulfoximines.
Accuracy of different cutoffs of the waist‐to‐height ratio as a screening tool for cardiometabolic risk in children and adolescents: A systematic rev…
2021
The present systematic review with meta-analysis sought to estimate the accuracy of different waist-to-height ratio (WHtR) cutoff ranges as risk indicators for cardiometabolic health in different populations of children and adolescents. Systematic searches were undertaken to identify studies in apparently healthy participants aged 3–18 years that conducted receiver operating characteristic curve analysis and reported area under the receiver operating characteristic curves for WHtR with any cardiometabolic biomarker. Forty-one cross-sectional studies were included in the meta-analysis, including 138,561 young individuals (50% girls). Higher area under summary receiver operating characteristi…
Prison officer students’ perceptions of persons convicted of sexual crimes
2021
This study investigated the dimensionality of the Perception of Sex Offenders scale among prison officer students in Norway, and whether the students’ perceptions of this group of prisoners changed during their theoretical education and 1-year practical training. The target sample comprised a full cohort of freshman prison officer students, and two waves of data collection were conducted. The response rate was 94 percent ( n = 188) at time 1 (T1) and 64 percent ( n = 112) at time 2 (T2). The originally reported three-dimensional structure of the Perception of Sex Offenders scale was replicated in our sample. Moreover, the results supported our hypothesis that prison officer students were l…
Rektors ar lielo burtu - Aleksandrs Veiss
2021
Raksts par profesoru, LPSR Zinātņu akadēmijas korespondētājlocekli, ķīmiķi un ilggadējo Rīgas Politehniskā institūta (mūsdienās - Rīgas Tehniskā universitāte) rektoru Aleksandru Veisu. Rakstā iespējams iepazīties ar Aleksandra Veisa biogrāfiju, sasniegumiem un piemiņu.
Exercise ECG Testing and Stress Cardiac Magnetic Resonance for Risk Prediction in Patients With Chronic Coronary Syndrome
2021
Vasodilator stress cardiac magnetic resonance (VS-CMR) has become crucial in the workup of patients with known or suspected chronic coronary syndrome (CCS). Whether traditional exercise ECG testing (ExECG) contributes prognostic information beyond VS-CMR is unclear.We retrospectively included 288 patients with known or suspected CCS who had undergone ExECG and subsequent VS-CMR in our institution. Clinical, ExECG, and VS-CMR variables were recorded. We defined the serious adverse events (SAE) as a combined endpoint of acute coronary syndrome, admission for heart failure, or all-cause death.During a mean follow-up of 4.2 ± 2.15 yr, we registered 27 SAE (15 admissions for acute coronary syndr…
Ikääntyvät suuret ikäluokat Japanin ja Suomen mediassa
2021
Identification and Evaluation of Hazardous Pyrolysates in Bio-Based Rigid Polyurethane-Polyisocyanurate Foam Smoke
2021
In this study, rigid polyurethane (PU) and polyisocyanurate (PIR) foam samples made from renewable material (tall oil fatty acid) based polyols were analyzed by pyrolysis gas chromatography mass spectrometry (Py-GC/MS) to obtain information about the full relative smoke content, with a focus on substance identification by their functional groups and hazardousness. The relative content of gaseous products produced during the thermal degradation was evaluated between the two samples, differenced by their assigned isocyanate (NCO) index value—150 and 300. The main thermal degradation components of the rigid PU-PIR foam were found to originate from the decomposition of isocyanate, primarily for…
Use of green alternative solvents in dispersive liquid‐liquid microextraction: A review
2021
Dispersive liquid-liquid microextraction is one of the most widely used microextraction techniques currently in the Analytical Chemistry field, mainly due to its simplicity and rapidity. The operational mode of this approach has been constantly changing since its introduction, adapting to new trends and applications. Most of these changes are related to the nature of the solvent employed for the microextraction. From the classical halogenated solvents (e.g., chloroform or dichloromethane), different alternatives have been proposed in order to obtain safer and non-pollutants microextraction applications. In this sense, low density solvents, such as alkanols, switchable hydrophobicity solvent…
Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells
2021
Abstract DNA is intrinsically dynamic and folds transiently into alternative higher-order structures such as G-quadruplexes (G4s) and three-way DNA junctions (TWJs). G4s and TWJs can be stabilised by small molecules (ligands) that have high chemotherapeutic potential, either as standalone DNA damaging agents or combined in synthetic lethality strategies. While previous approaches have claimed to use ligands that specifically target either G4s or TWJs, we report here on a new approach in which ligands targeting both TWJs and G4s in vitro demonstrate cellular effects distinct from that of G4 ligands, and attributable to TWJ targeting. The DNA binding modes of these new, dual TWJ-/G4-ligands w…
A systematic literature review on employee relations with CSR: State of art and future research agenda
2021
false
2021
Many phytophagous insects harbor symbiotic bacteria that can be transmitted vertically from parents to offspring, or acquired horizontally from unrelated hosts or the environment. In the latter case, plants are a potential route for symbiont transfer and can thus foster a tripartite interaction between microbe, insect, and plant. Here, we focus on two bacterial symbionts of the darkling beetle Lagria villosa that belong to the genus Burkholderia; the culturable strain B. gladioli Lv-StA and the reduced-genome strain Burkholderia Lv-StB. The strains can be transmitted vertically and confer protection to the beetle’s eggs, but Lv-StA can also proliferate in plants, and both symbiont strains h…
Redescription of Chiropturopoda nidiphila Wiśniewski & Hirschmann (Acari: Uropodina) from a woodpecker’s tree holes, including all development stages…
2021
All development stages of Chiropturopoda nidiphila Wiśniewski & Hirschmann, 1983 are described, which has previously been known only from the deutonymph stage. The species is closely associated with tree holes excavated by woodpeckers. Chiropturopoda nidiphila was redescribed and the genus diagnosis was completed. The description of the species morphology is based largely on scanning (SEM) electronograms. Diagnoses differentiating all of the known species of the genus Chiropturopoda are provided, including their developmental stages.
Retrospective Experiences of First-Episode Psychosis Treatment Under Open Dialogue-Based Services: A Qualitative Study.
2021
AbstractOpen Dialogue (OD) is an integrated approach to mental health care, which has demonstrated promising outcomes in the treatment of first-episode psychosis (FEP) in Finnish Western Lapland region. However, little is known how treatment under OD is retrospectively experienced by the service users themselves. To address this, twenty participants from the original Western Lapland research cohort diagnosed with psychosis (F20–F29) were asked about their treatment of FEP, initiated under OD 10–23 years previously. Thematic analysis was used to explore how the treatment was experienced. Most participants viewed network treatment meetings as an important part of their treatment, as they enab…
Towards comprehensive non-target screening using heart-cut two-dimensional liquid chromatography for the analysis of organic atmospheric tracers in i…
2021
Abstract Non-target screening of secondary organic aerosol compounds in ice cores is used to reconstruct atmospheric conditions and sources and is a valuable tool to elucidate the chemical profiles of samples with the aim to obtain as much information as possible from one mass spectrometric measurement. The coupling of mass spectrometry to chromatography limits the results of a non-target screening to signals of compounds within a certain polarity range based on the utilized stationary phases of the columns. Comprehensive two-dimensional liquid chromatography (LCxLC) introduces a second column of different functionality to enable the analysis of a broader range of analytes. Conventional LCx…
Redistribution of total reactive nitrogen in the lowermost Arctic stratosphere during the cold winter 2015/2016
2021
During winter 2015/2016 the Arctic stratosphere was characterized by extraordinarily low temperatures in connection with the occurrence of extensive polar stratospheric clouds. From mid of December 2015 until mid of March 2016 the German research aircraft HALO (High Altitude and Long–Range Research Aircraft) was deployed to probe the lowermost stratosphere in the Arctic region within the POLSTRACC (Polar Stratosphere in a Changing Climate) mission. More than twenty flights have been conducted out of Kiruna/Sweden and Oberpfaffenhofen/Germany, covering the whole winter period. Besides total reactive nitrogen (NOy), observations of nitrous oxide, nitric acid, ozone and water were used f…
Targeted SERPIN (TaSER): A dual‐action antithrombotic agent that targets platelets for SERPIN delivery
2021
BACKGROUND Occlusive thrombi are not homogeneous in composition. The core of a thrombus is rich in activated platelets and fibrin while the outer shell contains resting platelets. This core is inaccessible to plasma proteins. We produced a fusion protein (targeted SERPIN-TaSER), consisting of a function-blocking VH H against glycoprotein Ibα (GPIbα) and a thrombin-inhibiting serine protease inhibitor (SERPIN; α1-antitrypsin 355 AIAR358 ) to interfere with platelet-driven thrombin formation. AIM To evaluate the antithrombotic properties of TaSER. METHODS Besides TaSER, we generated three analogous control variants with either a wild-type antitrypsin subunit, a non-targeting control VH H, or …
Optimizing diagnostic algorithms to advance Hepatitis C elimination in Italy: A cost effectiveness evaluation
2021
Objectives: Optimized diagnostic algorithms to detect active infections are crucial to achieving HCV elimination. We evaluated the cost effectiveness and sustainability of different algorithms for HCV active infection diagnosis, in a context of a high endemic country for HCV infection. Methods: A Markov disease progression model, simulating six diagnostic algorithms in the birth cohort 1969‐1989 over a 10‐year horizon from a healthcare perspective was used. Conventionally diagnosis of active HCV infection is through detection of antibodies (HCV‐Ab) detection followed by HCV‐RNA or HCV core antigen (HCV‐Ag) confirmatory testing either on a second sample or by same sample reflex testing. The …
Fandiskurse über das (Re-)Naming von Stadionnamen in Deutschland und Frankreich ein diskurslinguistischer Ansatz
2021
International audience; Aktualität und RelevanzDer neueste Versuch eine European Super-League einzuführen verdeutlichte einmal mehr, dass Fußballfans nur noch als bloße Konsumenten des Produkts Fußball betrachtet werden. Allerdings belegten die Reaktionen von Politikern (The Economist 2021) und den Fans selbst, dass im europäischen Fußball andere Gesetzmäßigkeiten gelten als von Investoren angenommen. Gewinnmaximierung unter Ausschluss des sportlichen Wettbewerbs und ohne Berücksichtigung gewachsener Strukturen, Traditionen und Fankulturen scheint (noch) nicht vermittelbar (Mustroph 2021). Dass dennoch immer neue Geldquellen erschlossen werden, zeigt das wachsende Phänomen des Namensponsori…