Constitutive Rules: The Symbolization Account

2021

Our aim is to provide an account of constitutive rules in terms of (1) the acceptance of regulative norms, and (2) a cognitive process we call “symbolization” (in an altogether different sense from what J. R. Searle means by this word). We claim, first, that institutional facts à la Searle boil down to facts concerning the collective acceptance of regulative norms in a given community. This, however, does not exhaust what institutional facts are. There is a residue, symbolization. Symbolization, as we understand it, involves a transfer of cognitive models from one domain to another. We introduce this notion by exploring different sorts of games, taking our cue from games of pretend play. In…

Land use intensification increasingly drives the spatiotemporal patterns of the global human appropriation of net primary production in the last cent…

2021

Land use has greatly transformed Earth's surface. While spatial reconstructions of how the extent of land cover and land-use types have changed during the last century are available, much less information exists about changes in land-use intensity. In particular, global reconstructions that consistently cover land-use intensity across land-use types and ecosystems are missing. We, therefore, lack understanding of how changes in land-use intensity interfere with the natural processes in land systems. To address this research gap, we map land-cover and land-use intensity changes between 1910 and 2010 for 9 points in time. We rely on the indicator framework of human appropriation of net primar…

Between the Holy Cross and Free Market. Addressing the Issue of Homosexuality in the Narratives of Former Students in Polish Schools

2021

In the article the authors present the results of the research based on in-depth interviews with 22 young gays and lesbians, graduates of different types schools in Poland. The main goal of the research was to indicate how, in the opinions of the respondents, the issue of homosexuality was addressed in schools they attended and how these particular ways of treating homosexuality might be related to the wider socio-cultural context. The qualitative analysis of the narratives with the application of thematic analysis of the data let the authors identify four main categories comprising the ways of dealing with the issue of homosexuality (silence, pathologising attitude, the language of sin, po…

Agriculture biologique : les consommateurs ont fait plier les enseignes

2021

National audience

Assessment of Referees in Terms of Building a Positive Climate and Responsiveness to the Health, Emotional, and Social Needs of Rugby Players in Comp…

2021

One of the key elements of effective sports programs that contribute to a child’s sense of joy and satisfaction in participating in sports is contact with an adult who builds a caring climate deliberately and intentionally. Referees play a special role in providing positive experiences for young athletes. The main aim of this study was to assess the quality of referee–player interactions in terms of building a positive climate during the game and the referee’s responsiveness to the health, emotional, social, and cognitive needs of young rugby players aged 6–12 years. The research was conducted among 23 referees refereeing children’s rugby matches in Poland. The structure observation method …

On the hybrid origin of the C2Salsola divaricata agg. (Amaranthaceae) from C3 and C4 parental lineages

2021

AbstractC2 photosynthesis is characterized by recapturing photorespiratory CO2 by RuBisCO in Kranz-like cells and is therefore physiologically intermediate between C3 and C4 photosynthesis. C2 can be interpreted as an evolutionary precursor of C4 and/or as the result of hybridization between a C3 and C4 lineage.We compared the expression of photosynthetic traits among populations of the Salsola divaricata agg. (C2) from humid subtropical to arid habitats on the coasts of the Canary Islands and Morocco and subjected them to salt and drought treatments. We screened for enhanced C4-like expression of traits related to habitat or treatment. We estimated species trees with a transcriptome datase…

Safety and effectiveness of saving sphincter procedure in the treatment of chronic anal fissure in female patients.

2021

Abstract Introduction Lateral internal sphincterotomy (LIS) is still the approach of choice for the treatment of chronic anal fissure (CAF) regardless to the internal anal sphincter tone but it is burdened by high risk post-operative faecal incontinence (FI). In female patient there are some anatomical and functional differences of the sphinteric system which make them more at risk of FI and vaginal birth could cause sphinteric lesions affecting the anal continence function. The aim of our study is to evaluate the results of saving sphincter procedure as treatment for female patients affected by CAF. Methods We studied 110 female patients affected by CAF undergone fissurectomy and anoplasty…

Detection of Amyloid-β Fibrils Using Track-Etched Nanopores: Effect of Geometry and Crowding

2021

Several neurodegenerative diseases have been linked to proteins or peptides that are prone to aggregate in different brain regions. Aggregation of amyloid-β (Aβ) peptides is recognized as the main cause of Alzheimer's disease (AD) progression, leading to the formation of toxic Aβ oligomers and amyloid fibrils. The molecular mechanism of Aβ aggregation is complex and still not fully understood. Nanopore technology provides a new way to obtain kinetic and morphological aspects of Aβ aggregation at a single-molecule scale without labeling by detecting the electrochemical signal of the peptides when they pass through the hole. Here, we investigate the influence of nanoscale geometry (conical an…

Promoting Capabilities with a Drama Workshop among Foster Care Adolescents

2021

We assessed the impacts of a drama-based 13-session workshop among adolescents (N = 8) residing in a reform school due to severe conduct problems. The participants were interviewed three times duri...

A New Simple Computational Method of Simultaneous Constructing and Comparing Confidence Intervals of Shortest Length and Equal Tails for Making Effic…

2021

A confidence interval is a range of values that provides the user with useful information about how accurately a statistic estimates a parameter. In the present paper, a new simple computational method is proposed for simultaneous constructing and comparing confidence intervals of shortest length and equal tails in order to make efficient decisions under parametric uncertainty. This unified computational method provides intervals in several situations that previously required separate analysis using more advanced methods and tables for numerical solutions. In contrast to the Bayesian approach, the proposed approach does not depend on the choice of priors and is a novelty in the theory of st…

Observation of D0→K1(1270)−e+νe

2021

Using 2.93 fb^{-1} of e^{+}e^{-} collision data taken with the BESIII detector at a center-of-mass energy of 3.773 GeV, the observation of the D^{0}→K_{1}(1270)^{-}e^{+}ν_{e} semileptonic decay is presented. The statistical significance of the decay D^{0}→K_{1}(1270)^{-}e^{+}ν_{e} is greater than 10σ. The branching fraction of D^{0}→K_{1}(1270)^{-}e^{+}ν_{e} is measured to be (1.09±0.13_{-0.16}^{+0.09}±0.12)×10^{-3}. Here, the first uncertainty is statistical, the second is systematic, and the third originates from the assumed branching fraction of K_{1}(1270)^{-}→K^{-}π^{+}π^{-}. The fraction of longitudinal polarization in D^{0}→K_{1}(1270)^{-}e^{+}ν_{e} is determined for the first time t…

Search for Lepton Number and Flavor Violation in K+ and π0 Decays

2021

Searches for the lepton number violating $K^{+} \rightarrow \pi^{-} \mu^{+} e^{+}$ decay and the lepton flavour violating $K^{+} \rightarrow \pi^{+} \mu^{-} e^{+}$ and $\pi^{0} \rightarrow \mu^{-} e^{+}$ decays are reported using data collected by the NA62 experiment at CERN in $2017$-$2018$. No evidence for these decays is found and upper limits of the branching ratios are obtained at 90% confidence level: $\mathcal{B}(K^{+}\rightarrow\pi^{-}\mu^{+}e^{+})<4.2\times 10^{-11}$, $\mathcal{B}(K^{+}\rightarrow\pi^{+}\mu^{-}e^{+})<6.6\times10^{-11}$ and $\mathcal{B}(\pi^{0}\rightarrow\mu^{-}e^{+})<3.2\times 10^{-10}$. These results improve by one order of magnitude over previous results for thes…

The Psychology of Thinking in Creating AI

2021

The broad-scale emergence of AI in industry calls forth basic questions in terms of the knowledge bases and approaches relevant for its design. Engineering design has been mainly developed for electromechanical artifacts. In practice, this has meant that the scientific knowledge required for creating technical artifacts such as engines, cars, ships, cranes, telephones, radios, TVs, and simple data processing units has been natural science. However, one cannot find intelligent processes by means of physics and chemistry. Natural scientific phenomena follow their deterministic laws, but intelligence is based on selection and decision processes. The conceptual landscape of natural science is o…

The stakeholder's perception of socio-economic impacts generated by COVID-19 pandemic within the Italian aquaculture systems.

2021

From the beginning of March 2020 and for the following two and half months, many European countries comprising Italy have been forced into an unprecedented lockdown, allowing only the opening of essential economic activities needed to address the problems created by the pandemic (e.g. sanitary, food provision). Like many sectors of the Italian economy, aquaculture has also slowed down due to the ongoing emergency and the consequent closure of business. In our study we provided a ‘snapshot’ of the socio-economic effects of the lockdown on the aquaculture sector in Italy, immediately following the adoption of the COVID-19 restrictions as they were perceived by the workers. Although it was sur…

The legal balance between liberty and equality

2021

The paper explores the specific legal balance between liberty and equality, distinguishing it from political theories and constitutional settings, where they are often considered in opposition. In order to find the specific legal balance between liberty and equality, and after identifying some of their relevant meanings for the purpose, it becomes necessary to focus on the rule of law, and to examine the relationship between liberty and equality in its different versions. Once the core meaning of the rule of law in terms of liberty and equality is enucleated, it is possible to consider extending it to the international field.

Loss of a freshwater copepod species from El Junco Lake, Galápagos following the introduction and eradication of the Nile tilapia

2021

An undescribed diaptomid copepod probably belonging to a new Mastigodiaptomus species has been discovered and was very abundant in El Junco Lake (San Cristóbal Island, Ecuador) from 1966 until 2004. The species was not found in samples from 2007, 2008 or 2018. The loss of this key species from the lake coincides with the illegal introduction of Nile tilapia to El Junco Lake in 2005 and its subsequent eradication in 2008. The disappearance of this biogeographically and ecologically important copepod population may be explained by direct mechanisms of predation and competition, by a combination of both processes, and by indirect mechanisms linked to alterations in the lake ecosystem. The effe…

Excited states engineering enables efficient near-infrared lasing in nanographenes

2021

The spectral overlap between stimulated emission (SE) and absorption from dark states (i.e. charges and triplets) especially in the near-infrared (NIR), represents one of the most effective gain loss channel in organic semiconductors. Recently, bottom-up synthesis of atomically precise graphene nanostructures, or nanographenes (NGs), has opened a new route for the development of environmentally and chemically stable materials with optical gain properties. However, also in this case, the interplay between gain and absorption losses has hindered the attainment of efficient lasing action in the NIR. Here, we demonstrate that the introduction of two fluoranthene imide groups to the NG core lead…

Reduced-Dose Intravenous Thrombolysis for Acute Intermediate–High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism Internation…

2021

Intermediate-high-risk pulmonary embolism (PE) is characterized by right ventricular (RV) dysfunction and elevated circulating cardiac troponin levels despite apparent hemodynamic stability at presentation. In these patients, full-dose systemic thrombolysis reduced the risk of hemodynamic decompensation or death but increased the risk of life-threatening bleeding. Reduced-dose thrombolysis may be capable of improving safety while maintaining reperfusion efficacy. The Pulmonary Embolism International THrOmbolysis (PEITHO)-3 study (ClinicalTrials.gov Identifier: NCT04430569) is a randomized, placebo-controlled, double-blind, multicenter, multinational trial with long-term follow-up. We will c…

The Association between a MAOB Variable Number Tandem Repeat Polymorphism and Cocaine and Opiate Addictions in Polyconsumers

2021

Genetic analysis of the association between alcohol, cocaine, and opiate addiction and variable number tandem repeat (VNTR) polymorphisms in monoamine oxidase B (MAOB) and serotonergic 5-hydroxytryptamine (serotonin) receptor 1B and 2C (HTR1B 21 and HTR2C) pathway genes was performed in a sample of 302 polyconsumers. Our genetic association analysis revealed a significant association between a 184 base pair (bp) VNTR polymorphism in the MAOB gene and addiction to cocaine and opiates. This work highlights new genetic marker associations in cocaine and opiate polyconsumer addictions. These data help to clarify and quantify the complex role of genetics in addictive disorders, as well as their …

Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives

2021

Contains fulltext : 239279.pdf (Publisher’s version ) (Open Access) The reproducibility crisis (or replication crisis) in biomedical research is a particularly existential and under-addressed issue in the field of behavioral neuroscience, where, in spite of efforts to standardize testing and assay protocols, several known and unknown sources of confounding environmental factors add to variance. Human interference is a major contributor to variability both within and across laboratories, as well as novelty-induced anxiety. Attempts to reduce human interference and to measure more "natural" behaviors in subjects has led to the development of automated home-cage monitoring systems. These syste…

Social environmental impact of Covid-19 and erectile dysfunction: an explorative review

2021

Background-\ud \ud To date, no attempt has been made to collate literature on the relationship between the social environmental impact of COVID-19 and erectile dysfunction. The aim of this explorative review was to assess and compare the prevalence of erectile dysfunction (ED) in male healthcare workers and males during the COVID-19 pandemic.\ud \ud Methods-\ud \ud A systematic review of major databases from inception to February 2021 was conducted. Prevalence data were extracted, and a random-effects meta-analysis was undertaken.\ud \ud Outcomes-\ud \ud The pooled prevalence of ED amongst healthcare workers working in COVID-19 specific environments, and non-healthcare during the COVID-19 p…

Ni/Zn Layered Double Hydroxide (LDH) Micro/Nanosystems and Their Azorubine Adsorption Performance

2021

A membranous shaped Ni/Zn layered double hydroxide based nanohybrid was obtained using a low-cost template-free hydrothermal process at optimized growth conditions of 180 °C for 6 h. The synthesized nanohybrid was structurally, texturally and morphologically characterized using different techniques such as X-ray diffraction, FTIR, XPS spectroscopy, BET analysis and FESEM microscopy. The adsorption performance of our product was estimated through the Azorubine dye removal from synthetic wastewater. We therefore studied the synergic effects of Ni/Zn adsorbent dosage, contact time, pH, adsorbate concentration, stirring speed and temperature on the Azorubine adsorption efficiency. In this inves…

Ghost dynamics in the soft gluon limit

2021

We present a detailed study of the dynamics associated with the ghost sector of quenched QCD in the Landau gauge, where the relevant dynamical equations are supplemented with key inputs originating from large-volume lattice simulations. In particular, we solve the coupled system of Schwinger-Dyson equations that governs the evolution of the ghost dressing function and the ghost-gluon vertex, using as input for the gluon propagator lattice data that have been cured from volume and discretization artifacts. In addition, we explore the soft gluon limit of the same system, employing recent lattice data for the three-gluon vertex that enters in one of the diagrams defining the Schwinger-Dyson eq…

Are Traffic Announcements Really Effective? A Systematic Review of Evaluations of Crash-Prevention Communication Campaigns

2021

Communication campaigns are commonly used in the traffic and road safety sector to raise public awareness of the importance of avoiding risky road user attitudes and behaviors. Surprisingly few of these communication campaigns evaluate their effectiveness in a formal and comprehensive manner. The core aim of the present systematic review is to identify the type of studies that evaluate the effectiveness of campaigns in this sector, in order to identify and contrast their main findings. This systematic review followed the PRISMA methodology, by means of which the relevant articles based on the search term were identified. A total of 613 indexed articles were filtered, and a final set of 27 a…

Estrogen Receptor and Vascular Aging.

2021

Cardiovascular diseases remain an age-related pathology in both men and women. These pathologies are 3-fold more frequent in men than in women before menopause, although this difference progressively decreases after menopause. The vasculoprotective role of estrogens are well established before menopause, but the consequences of their abrupt decline on the cardiovascular risk at menopause remain debated. In this review, we will attempt to summarize the main clinical and experimental studies reporting the protective effects of estrogens against cardiovascular diseases, with a particular focus on atherosclerosis, and the impact of aging and estrogen deprivation on their endothelial actions. Th…

CHARACTERIZATION OF TRANSFORMED CELL LINES OBTAINED FROM PRIMARY RAT CORTICAL ASTROCYTES

2021

Brain cancers are complex and heterogeneous; most of them derive from glial cells[1], and are called gliomas, further subdivided into astrocytomas, oligodendrogliomas, ependymomas and glioastrocytomas[2]. The malignant cells undergo modifications of their metabolism and behaviour, and acquire the ability to migrate along the blood vessels in small groups (model of the guerrilla war)[3], thus invading the surrounding brain parenchyma. Most important, they have the capacity to affect the surrounding microenvironment, by altering both the extracellular matrix and the properties of the normal cells present in the brain, including glial-, endothelial-, and immune-cells, further promoting cancer …

La decadencia de la Sociología en la enseñanza secundaria en España: un análisis del impacto de la Lomce en la Sociología en la educación media posto…

2021

&#x0D; &#x0D; &#x0D; Este estudio es un análisis comparativo de la presencia de la asignatura de Sociología en el sistema educativo postobligatorio español. El objetivo de este es conocer cómo la promulgación de la Ley Orgánica no 8/2013, del 9 de diciembre, conocida como Lomce (Ley Orgánica para la Mejora de la Calidad Educativa), afectó a la presencia de la Sociología en el currículo educativo de todas las regiones de España. La metodología empleada ha sido el análisis de textos jurídicos y entrevistas telefónicas a centros educativos y profesorado. En suma, se ha comparado el cambio normativo que afecta a los currículos en las 17 regiones españolas, y se han recabado dat…

Le coup de crayon qui nous rend tous un peu scientifiques. Article sur la bande déssinée "Voyage au centre de la Pomme de terre"

2021

National audience

Count- versus MAD-based accelerometry-assessed movement behaviors and associations with child adiposity and fitness

2021

usc Estimations of time spent sedentary and in various physical activity intensities may vary according to data reduction methods applied. This study compared associations between children's accelerometer data and adiposity and fitness markers using open source (mean amplitude deviation, MAD) and proprietary (counts) data reduction methods. Complete-case accelerometer, adiposity (Body Mass Index z-score, waist circumference), and fitness (cardiorespiratory, musculoskeletal) data from 118 children (10.4 ± 0.6 years, 49% girls) were analyzed. Estimates of sedentary behavior, light-, moderate-, vigorous- (VPA), and moderate- to vigorous-intensity (MVPA) physical activity were calculated using …

L’effet direct et l’effet utile : même combat ?

2021

Colloque en format hybride (présentiel et à distance); National audience

Reduced Recombination Losses in Evaporated Perovskite Solar Cells by Postfabrication Treatment

2021

The photovoltaic perovskite research community has now developed a large set of tools and techniques to improve the power conversion efficiency (PCE). One such arcane trick is to allow the finished devices to dwell in time, and the PCE often improves. Herein, a mild postannealing procedure is implemented on coevaporated perovskite solar cells confirming a substantial PCE improvement, mainly attributed to an increased open-circuit voltage (V\(_{OC}\)). From a V\(_{OC}\) of around 1.11 V directly after preparation, the voltage improves to more than 1.18 V by temporal and thermal annealing. To clarify the origin of this annealing effect, an in-depth device experimental and simulation character…

Does Car Sharing Contribute to Urban Sustainability from User-Motivation Perspectives?

2021

Mobility, its current state and development perspectives in the future creates challenges with respect to sustainability, the first of which is the uncontrolled increase in greenhouse gas emissions in the last few decades, while road transport is one of the “sinners” creating long-term negative impact. The second is the dominance of car travel and car usage in the passenger transportation segment before the latest COVID-19 pandemic accelerated environmental problems. Although recent trends show new, greener patterns in consumption, there is still a relatively low share of consumers acknowledging the importance of sustainable and green preferences. This research study aims to investigate car…

Tilaa, seuraa ja ohjattua toimintaa

2021

Artikkelissa tutkitaan lapsille suunnattujen kaupunkiympäristöjen ja erityisesti ohjattujen leikkikenttien kehittymistä 1970-luvun Helsingissä. Lasten ympäristöjä ja niiden suunnitteluun vaikuttaneita lapsikäsityksiä tarkastellaan kolmen tason, rakennetun ympäristön, leikkikenttien arjen ja hyvinvointivaltion viitekehyksen kautta. Tutkimusaineistona on käytetty suunnitteludokumentteja, lapsista ja kaupunkiympäristöistä käytyä asiantuntijakeskustelua, sanomalehtikirjoituksia sekä entisten leikkikenttätoimijoiden kanssa tehtyjä haastatteluja. Artikkelissa esitetään, että lisääntyvistä lasten ympäristöjä koskevista normeista ja vähitellen kasvavasta valvonnasta huolimatta leikkikentät muotoutu…

L’aumento degli immatricolati nel Mezzogiorno d’Italia nell’anno accademico 2020-21: merito del Covid?

2021

LECTURA DEL ESCUDO DE RIOBAMBA A TRAVÉS DE LA HERÁLDICA Y LA EMBLEMÁTICA

2021

El ejercicio hermenéutico sobre el escudo de Riobamba ha nucleado a historiadores, cronistas y autoridades municipales, entre ellos, Pedro Traversari, diseñador del actual escudo ecuatoriano. Ante la escasez de documentos auténticos, Traversari acometió la interpretación del escudo a partir de la tradición y la narración de los historiadores Juan de Velasco y González Suárez. Dichas descripciones, hasta la fecha generan confrontaciones entre la población, en cuanto a reconocer al emblema como elemento de identidad. En este contexto, el objetivo del estudio es presentar una lectura alterna a la narración histórica del escudo de Riobamba fundamentados en la Heráldica y la Emblemática como her…

Atmospheric brightening counteracts warming‐induced delays in autumn phenology of temperate trees in Europe

2021

Aim: Ongoing climate warming has been widely reported to delay autumn phenology, which in turn impacts carbon, water, energy and nutrient balances at regional and global scales. However, the underlying mechanisms of autumn phenology responses to climate change have not been fully elucidated. The aims of this study were to determine whether brightening that was defined as the increase of surface solar radiation and warming during recent decades affect autumn phenology in opposite directions and explore the underlying mechanisms. Location: Central Europe. Time period: 1950–2016. Major taxa studied: Four dominant European tree species in central Europe: Aesculus hippocastanum, Betula pendula, …