Search results for "Nmr data"

showing 10 items of 21 documents

Investigations on organoantimony compounds

1976

Abstract Diorganoantimony(V) complexes of the type R 2 SbClTrid (R = Me, Ph) containing dianionic, potentially tridentate Schiff-base ligands with ONO donor atoms (Trid 2− ) have been prepared and characterized. IR and NMR data suggest an octahedral coordination environment for the antimony atom with meridional arrangement of the ONO ligand atoms and a linear CSbC skeleton.

StereochemistryLigandOrganic Chemistrychemistry.chemical_elementZonal and meridionalBiochemistryNmr dataInorganic ChemistryCrystallographyOctahedronAntimonychemistryMaterials ChemistryPhysical and Theoretical ChemistryJournal of Organometallic Chemistry
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Pyrimido[5,4-c]pyrrolo[2,1-a]isoquinoline: a new potential DNA-interactive ring system

2003

The acid catalyzed decomposition of the azide 9 failed to give the title compounds, which were however obtained by a Pschorr-type cyclization on reactive 1-(6-aminopyrimidin-5-yl)-pyrroles of type 13. Derivatives of type 14 and 15 were fully characterized by NMR data. Theoretical calculations demonstrated that the new compounds possess properties suitable for DNA- intercalation.

StereochemistryOrganic ChemistryIntercalation (chemistry)Ring (chemistry)DecompositionNmr datalcsh:QD241-441chemistry.chemical_compoundchemistrylcsh:Organic chemistryAcid catalyzedAzideIsoquinolineDNAARKIVOC
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Terphenyl Derivatives from Allantophomopsis lycopodina.

2016

Three secondary fungal metabolites 1–3 with a benzo[b]naphtho[2,1-d]furan skeleton were isolated from submerged cultures of the ascomycete Allantophomopsis lycopodina. The NMR-based structure elucidation was challenging due to a low H/C ratio of only 0.64 and 0.68, respectively. NMR measurements in two different solvents and the use of NMR experiments such as HSQC-TOCSY and LR-HSQMBC proved to be helpful in this respect. The proposed structures obtained from the comprehensive analysis of the NMR data were verified by comparison of recorded and computed NMR chemical shifts from quantum chemical calculations of several constitutional isomers and were further analyzed with the aid of the DP4 a…

StereochemistryPharmaceutical ScienceAllantophomopsis lycopodina010402 general chemistry01 natural sciencesAnalytical Chemistrychemistry.chemical_compoundAscomycotaComputational chemistryTerphenylFuranTerphenyl CompoundsDrug DiscoveryStructural isomerNuclear Magnetic Resonance BiomolecularPharmacologyQuantum chemicalMolecular Structure010405 organic chemistryChemical shiftOrganic ChemistryNmr data0104 chemical sciencesComplementary and alternative medicinechemistryMolecular MedicineJournal of natural products
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Dual Substituent Parameter Modeling of Theoretical, NMR and IR Spectral Data of 5-Substituted Indole-2,3-diones

2002

Correlations of AM1 and PM3 theoretical data, 13C-NMR substituent chemical shifts (13C-SCS) and IR carbonyl group wave numbers [ν(C3â•ÂO)] were studied using dual substituent parameter (DSP) models for 5-substituted indole-2,3-diones. For the C7 atom a reverse substituent effect attributed to extended À-polarization was observed. On the other hand, the DSP approaches for the C3 atom showed normal substituent effects with some contribution of reverse effect supported strongly by 13C-SCS correlations. In the ν(C3â•ÂO) and p(C3â•ÂO) DSP correlations the field effect contribution predominates over the resonance effect, which justifies the using of earlier suggested vibrational cou…

StereochemistrySubstituentPharmaceutical ScienceField effectArticleAnalytical Chemistry3-dioneslcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistry5-Substituted indole-23-dionesDrug DiscoveryAtomAM1 and PM3 theoretical dataπ-polarizationWavenumberPhysical and Theoretical ChemistrySpectral dataIndole testreverse substituent effectChemistryChemical shiftOrganic ChemistryIR and NMR data DSP correlationsChemistry (miscellaneous)5-Substituted indole-2Molecular MedicinePhysical chemistryÀ-polarizationRotational–vibrational couplingMolecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
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A sterically congested 1,2-diphosphino-1'-boryl-ferrocene: synthesis, characterization and coordination to platinum.

2019

International audience; A new class of tritopic ferrocene-based ambiphilic compound has been prepared by assembling diphosphino- and boryl-substituted cyclopentadienides at iron. The presence of five sterically demanding substituents on the ferrocene platform induces conformation constraints, as apparent from XRD and NMR data, but does not prevent chelating coordination to platinum. The Lewis acid moiety is pendant in both the free ligand and the platinum complex.

Steric effects010405 organic chemistryChemistryLigandchemistry.chemical_element010402 general chemistry01 natural sciencesNmr data3. Good health0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundFerrocenePolymer chemistry[CHIM]Chemical SciencesMoietyChelationLewis acids and basesPlatinumDalton transactions (Cambridge, England : 2003)
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Donellanic acids A–C: new cyclopropanic oleanane derivatives from Donella ubanguiensis (Sapotaceae)

2012

Abstract Three new cyclopropanic oleanane triterpenoids and ten known compounds were obtained from Donella ubanguiensis using chromatographic methods. The structures were established on the basis of mass spectrometric and NMR data and by comparison with values reported in the literature. The structures of the new compounds were confirmed by X-ray crystallography. A part of the isolated compounds was evaluated for cytotoxic and antimicrobial activities.

biologyStereochemistryOrganic Chemistrybiology.organism_classificationAntimicrobialBiochemistrySapotaceaeNmr dataMass spectrometricchemistry.chemical_compoundTriterpenoidchemistryDrug DiscoveryOrganic chemistryOleananeTetrahedron
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Bafouoside C, a new triterpenoid saponin from the roots of Cussonia bancoensis Aubrev. & Pellegr.

2014

Abstract A new triterpenoid saponin named bafouoside C 3-O-β- d -glucopyranosyl-(1 → 4)-[β- d -galactopyranosyl-(1 → 2)]-β- d -glucuronopyranosyloleanolic acid 28-O-β- d -glucopyranosyl ester; (1), together with five known compounds 3-O-β- d -galactopyranosyl-(1 → 2)-β- d -glucuronopyranosyloleanolic acid (2), 23-hydroxyursolic acid (3), 28-O-α- l -rhamnopyranosyl-(1 → 4)-O-β- d -glucopyranosyl-(1 → 6)-O-β- d -glucopyranosyl-23-hydroxyursolic acid (4), 3-O-β- d -glucopyranosyl-23-hydroxyursolic acid (5), and 3-O-α- l -arabinopyranosyl-23-hydroxyursolic acid (6), were isolated from the roots of Cussonia bancoensis Aubrev. & Pellegr. Their structures were established on the basis of 1D- and 2…

chemistry.chemical_classificationbiologyCussoniaStereochemistryPlant Sciencebiology.organism_classificationBiochemistryNmr datachemistryCarcinoma CellAraliaceaeAgronomy and Crop ScienceHuman breastTwo-dimensional nuclear magnetic resonance spectroscopyHuman colonBiotechnologyTriterpenoid saponin
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ChemInform Abstract: Studies on Bicyclo[3.3.1]nonanes for Synthesis of Cyclooctenes.

2010

This paper describes a full conformational and stereochemical study of bicylo[3.3.1]nonanes, obtained from the reaction between cinnamaldehyde and 1-morpholine 1-cyclohexene. NMR data and stereochemistry were unequivocally established and assigned by two-dimensional experiments and single-crystal X-ray analysis. The crystal structure of a minor compound, 4, is reported. Cyclooctenes, which are present in natural products with biological activities, were synthesized from the bicyclononanes via the Wharton fragmentation.

chemistry.chemical_classificationchemistry.chemical_compoundchemistryBicyclic moleculeStereochemistryGeneral MedicineCrystal structureBridged compoundsNmr dataCinnamaldehydeChemInform
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Addition reactions of heterocycles. VII. Pyrrole andC-Acetyl-N-phenylnitrilimine

1978

The addition reaction of C-acetyl-N-phenylnitrilimine to pyrrole has been investigated. The products obtained show that the reaction proceeds via two distinct pathways. The 1,3-addition reaction leads to the non-cyclic-adduct III, whereas the 1,3-cycloaddition reaction gives a mixture of regioisomeric Δ2-pyrroline IV and V, and Δ1 -pyrroline VI and VII mono-cycloadducts. These latter compounds cannot be isolated because they undergo a further 1,3-cycloaddition reaction leading to the N-substituted bis-adducts X and XI, and to the bis-adduets XII and XIII. The stereochemical assignment for X, XI, XII and XIII is provided by nmr data which suggest also that in X and XI the rotation around the…

chemistry.chemical_compoundAddition reactionchemistryStereochemistryOrganic ChemistryPyrrolineNmr dataPyrroleJournal of Heterocyclic Chemistry
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STUDIES ON BICYCLO[3.3.1]NONANES FOR SYNTHESIS OF CYCLOOCTENES

2002

This paper describes a full conformational and stereochemical study of bicylo[3.3.1]nonanes, obtained from the reaction between cinnamaldehyde and 1-morpholine 1-cyclohexene. NMR data and stereochemistry were unequivocally established and assigned by two-dimensional experiments and single-crystal X-ray analysis. The crystal structure of a minor compound, 4, is reported. Cyclooctenes, which are present in natural products with biological activities, were synthesized from the bicyclononanes via the Wharton fragmentation.

chemistry.chemical_compoundBicyclic moleculeChemistryStereochemistryOrganic ChemistryCrystal structureNmr dataCinnamaldehydeSynthetic Communications
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