showing 36 of ~574560 from 574555 documents
Horizon Europe, the new programme for research & innovation: Which opportunities for GI research in the years to come?
2021
Method for Reproducible Shipboard Segmented Flow Analysis Ammonium Measurement Using an In-House Reference Material for Quality Control
2021
Ammonium is a fundamental nutrient for phytoplankton growth in seawater and is a key component of the microbial loop. Ammonium measured in parallel with other nutrients is crucial in understanding the small temporal scale changes in oceanographic ecology. Despite the importance of measuring ammonium at sea, owing to its lability, there is no consensus on the best method. The lack of availability of certified reference materials for ammonium in seawater also makes it difficult to assess the accuracy and reproducibility of ammonium measurements. In this study we present a modified segmented flow analysis method using ortho-phthaldialdehyde (OPA) with fluorescence detection to measure ammonium…
Cognitive reappraisal and self-compassion as emotion regulation strategies for parents during COVID-19: An online randomized controlled trial
2021
Objective Parenting during pandemic restrictions places extreme demands on everyday family life, leading to increased stress levels for parents and distressed parent-child interactions. This RCT aimed to investigate whether cognitive reappraisal and self-compassion are helpful emotion regulation (ER) strategies to reduce individual and parental stress during the COVID-19 pandemic. Method An online intervention for parents was developed focusing on the application of ER strategies to pandemic requirements of families. A sample of 265 parents were randomly assigned to either cognitive reappraisal (CR; n = 88), self-compassion (SC; n = 90) or wait-list control (WLC; n = 87) group. Intervention…
COMPAS : une application innovante pour soutenir la communication centrée sur la personne entre les personnes âgées atteintes de démence et leur proc…
2021
Introduction Les personnes atteintes de demence (PAD) developpent des troubles de la communication qui impactent la relation avec l’aidant ce qui contribue a l’isolement de l’un et a l’epuisement de l’autre. Objectifs L’objectif est de valider COMmunication Proche-Aidants (COMPAs) en contexte de soins de longue duree. Cette application favorise les interactions grâce a du contenu audiovisuel personnalise permettant une communication centree sur la personne. Patients et methodes 17 aides-soignants ont utilise quotidiennement COMPAs aupres de 39 beneficiaires atteints de troubles neurocognitifs majeurs pendant huit semaines. L’etude mesure les effets de COMPAs sur la communication, la qualite…
Real-world experience with obeticholic acid in patients with primary biliary cholangitis
2021
Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of OCA under real-world conditions. Methods Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. The primary endpoint was the biochemical response according to Poise criteria; the secondary endpoint was the biochemical response according to normal range criteria, defined as normal levels of bilirubin, alkaline phosphatase (ALP), and alanine aminotransfer…
Active biopackaging produced from by‐products and waste from food and marine industries
2021
The agro‐food industry cannot today do without packaging to preserve and above all market its products. Plastic materials coming mainly from petrochemicals have taken a predominant place in the food packaging sector. They have become indispensable in many sectors, from fresh to frozen products, from meat and dairy products to fruit and vegetables or almost‐ready meals. Plastics are cheap, their lightness reduces transport costs, and their convenience is fundamental for out‐of‐home catering. However, plastics pose serious end‐of‐life issues. The development of materials that are more respectful of the consumer and the environment has become a major issue. In addition, the agro‐food industrie…
Deadlines don’t prevent cramming: Course instruction and individual differences predict learning strategy use and exam performance
2021
Abstract The goal of the present study was to investigate how course instruction and individual differences in general academic competences and conscientiousness relate to students' learning strategy use and exam performance. The sample comprised two cohorts of university students who attended a lecture on the same topic, but with varying course instruction: In the blended course (N = 238), the teacher applied deadlines for self-testing and offered regular in-class meetings to encourage distributed practice over the semester. In the online course, students studied independently without regular meetings, nor deadlines (N = 200). Learning strategies were measured objectively using behavioral …
Tailoring a pair of pants
2021
Abstract We show how to deform the map Log : ( C ⁎ ) n → R n such that the image of the complex pair of pants P ∘ ⊂ ( C ⁎ ) n is the tropical hyperplane by showing an (ambient) isotopy between P ∘ ⊂ ( C ⁎ ) n and a natural polyhedral subcomplex of the product of the two skeleta S × Σ ⊂ A × C of the amoeba A and the coamoeba C of P ∘ . This lays the groundwork for having the discriminant to be of codimension 2 in topological Strominger-Yau-Zaslow torus fibrations.
The cost of open access publication of papers by spanish authors in five areas of the social sciences
2021
[ES] La publicación en abierto de los artículos conlleva unos gastos conocidos como cargos por procesamiento de artículos (APC, en sus siglas en inglés). El objetivo de este trabajo es determinar el coste de los artículos publicados en abierto mediante APC de autoría española en cinco categorías temáticas de las ciencias sociales: Humanities (Multidisciplinary), Sociology, Information Science & Library Science, Education & Educational Research y Communication de la Colección Principal de la Web of Science (WoS) durante el periodo 2012-2019. Se han identificado las revistas, las instituciones financiadoras y los modelos de publicación más frecuentes. El estudio indica que de las 223 revistas…
Is a Mask That Covers the Mouth and Nose Free from Undesirable Side Effects in Everyday Use and Free of Potential Hazards?
2021
International journal of environmental research and public health : IJERPH 18(8), 4344 (2021). doi:10.3390/ijerph18084344
Retracted papers on SARS-CoV-2 and COVID-19
2021
Un Parco nella Sicilia più nascosta
2021
Le aree interne della Sicilia sono caratterizzate, oltre che dalle tipiche crisi delle aree marginali, da altri fattori peculiari quali una costante arretratezza tecnologica e uno disfattismo di gattopardesca memoria. Esse sono anche però il luogo ove lo sviluppo locale potrebbe riportare i suoi migliori esiti, trasformandole da luoghi del sottosviluppo in luoghi di rinnovata e viva identità. Ciò in virtù dalla immensa potenzialità che luoghi naturali come i Parchi possiedono intrinsecamente per avviare uno sviluppo sostenibile che riesca a mantenere le componenti identitarie e paesaggistiche di un luogo e al contempo risollevarne le sorti. Il caso studio, ivi presentato, riguarda il Parco …
Randomized renaming in shared memory systems.
2021
Abstract Renaming is a task in distributed computing where n processes are assigned new names from a name space of size m . The problem is called tight if m = n , and loose if m > n . In recent years renaming came to the fore again and new algorithms were developed. For tight renaming in asynchronous shared memory systems, Alistarh et al. describe a construction based on the AKS network that assigns all names within O ( log n ) steps per process. They also show that, depending on the size of the name space, loose renaming can be done considerably faster. For m = ( 1 + ϵ ) ⋅ n and constant ϵ , they achieve a step complexity of O ( log log n ) . In this paper we consider tight as well as loos…
Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases
2021
Abstract Background In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infecti…
Management of Childhood Obesity—Time to Shift from Generalized to Personalized Intervention Strategies
2021
As a major public health concern, childhood obesity is a multifaceted and multilevel metabolic disorder influenced by genetic and behavioral aspects. While genetic risk factors contribute to and interact with the onset and development of excess body weight, available evidence indicates that several modifiable obesogenic behaviors play a crucial role in the etiology of childhood obesity. Although a variety of systematic reviews and meta-analyses have reported the effectiveness of several interventions in community-based, school-based, and home-based programs regarding childhood obesity, the prevalence of children with excess body weight remains high. Additionally, researchers and pediatric c…
The regulation of emotions: Gender differences
2021
IntroductionEmotional regulation, understood as the emotional ability to repair emotional states, is a skill closely linked to adaptation during aging. People who are capable to manage their emotions have greater control over moods, applying adaptive regulation strategies that allow them to maintain positive moods and modify or regulate negative ones. It has been observed that gender can be a relevant variable related to emotional regulation. In this sense, it is considered that women may be more skillful than men to emotional regulation strategies, benefiting from more successful emotional management strategies.ObjectivesVerify if there are differences in the ability of emotional regulatio…
The Role for Combined Antithrombotic Therapy with Platelet and Coagulation Inhibition After Lower Extremity Revascularization
2021
Evidence for antithrombotic treatment following lower extremity revascularization (LER) for peripheral artery disease (PAD) is limited, leading to weak and conflicting guideline recommendations and heterogeneous practice patterns. This variability in post-LER antithrombotic treatment raises quality-of-care issues that have long been under-studied. This Viewpoint reviews the most updated guidelines, currently-available evidence, and contemporary data about practice patterns and practitioner opinions in this area. Particular attention is paid to distinctions between antiplatelet therapy, anticoagulant therapy, and combination therapy in light of the recent VOYAGER-PAD (Vascular Outcomes Study…
Linear, tripodal, macrocyclic: Ligand geometry and ORR activity of supported Pd(II) complexes
2021
Abstract The novel ligand H3L designed to spontaneously adsorb onto MWCNT via electron-deficient pyrimidine residues and bind metal cations is used to prepare an oxygen reduction reaction (ORR) cathode catalyst based on supported Pd(II) complexes. Herein we report the synthesis of the ligand, its solution behaviour (protonation constants, binding constants for the test cation Cu(II), UV evidence of Cu(II) and Pd(II) complexes formation) and ORR performances together with XPS and STEM characterization. Tripodal nature of the H3L ligand frame it in-between previously studied macrocyclic and linear open chain ligands, allowing to draw meaningful comparisons.
Syntaxonomy and biogeography of the Irano‐Turanian mires and springs
2021
Aims: To develop the first comprehensive syntaxonomic classification for patchy montane mire and spring vegetation across the Irano-Turanian phytogeographical region in Iran, Tajikistan and Kyrgyzstan and to explore the effects of the main environmental and geographic gradients on their distribution. Location: Alborz Mountain range (Iran), Pamir-Alai Mountains (Tajikistan) and Tian Shan Mountains (Kyrgyzstan); total area of about 3,000,000 km2. Methods: A database of 1,015 vegetation relevés including a total of 675 vascular and bryophyte taxa was established, covering the large mountains ranges of the Irano-Turanian regions in Iran, Tajikistan and Kyrgyzstan, at altitude ranging from 1,300…
Green Design of Novel Starch-Based Packaging Materials Sustaining Human and Environmental Health
2021
A critical overview of current approaches to the development of starch-containing packaging, integrating the principles of green chemistry (GC), green technology (GT) and green nanotechnology (GN) with those of green packaging (GP) to produce materials important for both us and the planet is given. First, as a relationship between GP and GC, the benefits of natural bioactive compounds are analyzed and the state-of-the-art is updated in terms of the starch packaging incorporating green chemicals that normally help us to maintain health, are environmentally friendly and are obtained via GC. Newer approaches are identified, such as the incorporation of vitamins or minerals into films and coati…
Monitoring Occurrence of Liver-Related Events and Survival by Transient Elastography in Patients With Nonalcoholic Fatty Liver Disease and Compensate…
2021
[Background & Aims] Patients with advanced fibrosis related to nonalcoholic fatty liver disease (NAFLD) are at risk of developing hepatic and extrahepatic complications. We investigated whether, in a large cohort of patients with NAFLD and compensated advanced chronic liver disease, baseline liver stiffness measurements (LSMs) and their changes can be used to identify patients at risk for liver-related and extrahepatic events.
Anxiety and facial self-contacts: possible impact on COVID-19 transmission in dental practice
2021
Abstract Background The purpose was to analyse the associations between dental and trait anxiety, fear of COVID-19 and the duration and frequency of spontaneous hand-to-face contact (self-contact). Methods A cross-sectional design was carried out with 128 adult patients from four dental clinics in Madrid, during the confinement, from March 15 to May 15. The patients’ movements in the waiting room were monitored with Microsoft Kinect Software, also completed the Trait anxiety subscale of the STAI, the COVID-19 Fear and the S-DAI questionnaire. Results Associations were observed between the duration and frequency of facial, mask and eye contact with trait anxiety and dental fear was determine…
The role of thought suppression and psychological inflexibility in older family caregivers’ psychological symptoms and quality of life
2021
Abstract Background Family caregivers often report high levels of distress, including depressive symptoms, anxiety, and reduced quality of life. There is a need for a greater understanding of the factors influencing, explaining, and maintaining psychological distress in family caregivers. Aim The aim of this study was to examine whether avoidance strategies such as thought suppression (WBSI), psychological inflexibility (AAQ-II), and, and caregiver experiential avoidance (EACQ) predict psychological distress (BDI-II, GAD-7) and quality of life (WHOQOL) in family caregivers aged 60 and over. We hypothesized that these avoidance strategies would explain elevated levels of psychological sympto…
Short X···N Halogen Bonds With Hexamethylenetetraamine as the Acceptor
2021
Hexamethylenetetramine (HMTA) and N-haloimides form two types of short (imide)X···N and X–X···N (X = Br, I) halogen bonds. Nucleophilic substitution or ligand-exchange reaction on the peripheral X of X–X···N with the chloride of N-chlorosuccinimide lead to Cl–X···N halogen-bonded complexes. The 1:1 complexation of HMTA and ICl manifests the shortest I···N halogen bond [2.272(5) Å] yet reported for an HMTA acceptor. Two halogen-bonded organic frameworks are prepared using 1:4 molar ratio of HMTA and N-bromosuccinimide, each with a distinct channel shape, one possessing oval and the other square grid. The variations in channel shapes are due to tridentate and tetradentate (imide)Br···N coordi…
Behavioral reasoning perspectives to brand love toward natural products: Moderating role of environmental concern and household size
2021
Abstract Consumers do not easily trust brands’ claims of naturalness, making it essential to understand the drivers of loyalty and the underlying brand love for such products. Responding to this need, the present study developed a conceptual model based on the Behavioral Reasoning Theory (BRT) to examine the antecedents of brand love. The model was tested using data collected through a cross-sectional survey. The findings suggest that health consciousness is positively associated with reasons for consuming natural products and attitude, which, in turn, are also positively associated with each other. At the same time, reasons for consuming natural products and attitude are positively associa…
Young Talents in Polymer Science.
2021
Qualitative traits and shelf life of fig fruit (cv Melanzana) treated with Aloe vera gel coating
2021
The fig (Ficus carica L.) cv Melanzana is typical of Southern Italy. This cultivar produces breba fruit in June and fig fruit in August. Some previous studies on the use of coatings extracted from stems of Aloe vera showed positive effects to maintain fruit quality during shelf life. However, there are no studies on breba fig fruit treated with Aloe vera coating. In this study breba fig fruit, cv Melanzana, was treated with an application of Aloe vera gel, sealed in macro-perforated bag and stored at 5°C for 10 days. The effect of application of the Aloe vera gel on the shelf-life of this fruit, and its quality attributes after application were evaluated measuring fresh weight, total solubl…
Talking Blockchains: The Perspective of a Database Researcher
2021
There are few topics out there, that seem to create as much confusion and discussion as blockchains. This has a multitude of reasons: (1) A large number of drastically different concepts and systems are unified under the very broad term "blockchain". (2) The topic touches a variety of different fields, including databases, distributed processing, networks, cryptography, and even economics. (3) There exists a large number of different applications of the technology.The goal of this paper is to simplify and structure the discussion of blockchain technology. We first introduce a simple formalization of the basic components, that appear again and again in a variety of blockchain systems. Second…
Development and Validation of the Test of Orthorexia Nervosa (TON-17)
2021
This study aims to develop and validate a new self-report questionnaire to measure orthorexia nervosa (ON). Based on a current review of the scientific literature and interviews with people at risk of orthorexia, 40 items were selected to test orthorexia nervosa (TON-40). A total sample of 767 individuals (M = 26.49, SD = 9.66, 56.98% women) participated in the study. The exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and composite construct analysis (CCA) were performed to find an appropriate model of sufficient reliability and validity and stable construction. Convergent validation was performed regarding the correlation of the TON-17 with another measure of ON (OR…
(Trifluoromethoxy)Phenylboronic Acids: Structures, Properties, and Antibacterial Activity.
2021
Three isomers of (trifluoromethoxy)phenylboronic acids were studied in the context of their physicochemical, structural, antimicrobial and spectroscopic properties. They were characterized by 1H, 13C, 11B and 19F NMR spectroscopy. The acidity of all the isomers was evaluated by both spectrophotometric and potentiometric titrations. The introduction of the -OCF3 group influences the acidity, depending, however, on the position of a substituent, with the ortho isomer being the least acidic. Molecular and crystal structures of ortho and para isomers were determined by the single crystal XRD method. Hydrogen bonded dimers are the basic structural motives of the investigated molecules in the sol…
OLTRE L’UMANO. APOCALISSI E COSMOGONIA NEL PIANETA IRRITABILE DI PAOLO VOLPONI
2021
Il saggio rilegge "Il pianeta irritabile" come storia di una cosmogonia, in cui le istanze fantascientifiche convivono con le ragioni allegoriche e con le suggestioni dell’antropologia. "Il pianeta irritabile" ha inizio dopo una catastrofe atomica, quando un diluvio di acqua, petrolio, sabbia e madreperla cancella il «vecchio ordine» basato sulla sovranità dell’umano e sulla logica artificiale del capitale. Il nano Mamerte, l’oca Plan Calcule, l’elefante Roboamo, sotto la guida del babbuino Epistola, compiono un viaggio alla ricerca di una possibile salvezza. Il passaggio dal caos dell’apocalisse alla rifondazione di un’«immortalità selvaggia» è scandito da prove iniziatiche, da lotte e da …
Is there a need to widely prescribe antibiotics in patients hospitalized with COVID-19?
2021
Highlights • Antibiotics were a main part of COVID-19 treatments during the first epidemic peak. • Bacterial coinfections seem to be rare, especially if no ICU transfer needed. • We studied the place of antibiotics and the impact on prognosis of patients. • Antibiotics were prescribed if more severe infection and has no impact on prognosis. • We think that antibiotic therapy must be not widely prescribed.
One-Year Evolution of Symptoms and Health Status of the COPD Multi-Dimensional Phenotypes: Results from the Follow-Up of the STORICO Observational St…
2021
Raffaele Antonelli Incalzi,1 Francesco Blasi,2,3 Nicola Scichilone,4 Alessandro Zullo,5 Lucia Simoni,5 Giorgio Walter Canonica6 On Behalf of STORICO study group1Internal Medicine and Geriatrics Department Biomedical Campus University of Rome, Rome, Italy; 2Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy; 3Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 4DIBIMIS, University of Palermo, Palermo, Italy; 5Medineos Observational Research, Modena, Italy; 6Personalized Medicine Asthma & Allergy Clinic, Humanitas University, Humanitas &…
Relocation of an infected tracheostoma: anterior mediastinal tracheostomy as Mission:Impossible
2021
Abstract Infected tracheostomas are frequently associated with high morbidity and mortality rates—especially in patients after neck-oncological surgery with subsequent radiochemotherapy. A 59-year-old male patient with a history of hypopharynx carcinoma, successive laryngectomy and adjuvant radiochemotherapy developed an oesophagotracheal fistula with massive inflammation and periodical bleedings, uncontrollable by regular stent alternations. In a multidisciplinary setting, the decision was made to treat the patient with an anterior mediastinal tracheostomy. Extending usual anterior mediastinal tracheostomy indications, we present an ultimate treatment option for infected tracheostomas and …
Comments on “Overflow characteristics of streamlined weirs based on model experimentation” by Bagheri S. and Kabiri-Samani A
2021
Abstract In this paper the stage-discharge equation of a streamlined weir is theoretically deduced applying the Π-Theorem of dimensional analysis and the self-similarity theory. The coefficients of the new stage-discharge relationship are estimated using the experimental results by Bagheri and Kabiri-Samani.
PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastri…
2021
International audience; Gastric or gastro-oesophageal junction (GEJ) adenocarcinomas present poor overall survival (OS). First-line chemotherapy regimen for patients with HER2-negative tumours is based on a doublet or triplet of fluoropyrimidine plus platinum salt ± taxane. Second-line chemotherapy (Docetaxel or Irinotecan) improves OS which nonetheless remains poor (around 5 months). The first results of immune checkpoint inhibitors (anti-PD-1) combined with chemotherapy in metastatic gastric and GEJ cancers were discordant in recent phase III trials. Data on dual-blockade (anti-PD-L1 or anti-PD-1 plus anti-CTLA-4) plus chemotherapy are lacking. DURIGAST is a randomised, multicenter, non-c…