showing 36 of ~574560 from 574555 documents
Psychological Profile in Female Cyclists and Its Relationship with Age, Training Parameters, Sport Performance, and Injury Incidence.
2021
Previous studies have highlighted the importance of psychology on sports performance and its relationship with the incidence of sport injuries. The objectives of the present investigation were: (1) to analyze the psychological profile of female cyclists as a function of age, training parameters, sport performance, and injuries suffered and (2) to design a model to predict their psychological profile. Sixty-one female cyclists participated in the study. Differences were found as a function of a competitive category for team cohesion (F = 5.035
Unraveling the thread of uncontrolled immune response in COVID-19 and STEMI: an emerging need for knowledge sharing
2021
The outbreak of severe acute respiratory syndrome coronavirus 2 that first emerged in Wuhan in December 2019 has resulted in the devastating pandemic of coronavirus disease 2019, creating an emerging need for knowledge sharing. Meanwhile, myocardial infarction is and will probably remain the foremost cause of death in the Western world throughout the coming decades. Severe deregulation of the immune system can unnecessarily expand the inflammatory response and participate in target and multiple organ failure, in infection but also in critical illness. Indeed, the course and fate of inflammatory cells observed in severe ST-elevation myocardial infarction (neutrophilia, monocytosis, and lymp…
Toward ‘Vaccine Internationalism’: The Need for an Equitable and Coordinated Global Vaccination Approach to Effectively Combat COVID-19
2021
International audience
Mobiliser le levier génétique pour améliorer et stabiliser la valeur protéique des graines de pois
2021
National audience; Présentation de l'Atelier :Les protéines sont des macronutriments majeurs dans l’alimentation des hommes et des animaux. Or la production de protéines végétales est toujours déficitaire en France qui a recours à des importations pour couvrir ses besoins.Les légumineuses contiennent plus de protéines que les céréales. En outre, leur culture contribue à la mise en œuvre de systèmes moins demandeurs en intrants qui peuvent ainsi, seuls, en rotation ou en mélange, contribuer efficacement à la démarche one health, vers une meilleure santé globale des hommes, des animaux, des cultures et de l’environnement. Améliorer la qualité des protéines végétales, tout en maintenant voire …
Genome-wide analyses reveal population structure and identify candidate genes associated with tail fatness in local sheep from a semi-arid area.
2021
Abstract Under a climate change perspective, the genetic make-up of local livestock breeds showing adaptive traits should be explored and preserved as a priority. We used genotype data from the ovine 50 k Illumina BeadChip for assessing breed autozygosity based on runs of homozygosity (ROH) and fine-scale genetic structure and for detecting genomic regions under selection in 63 Tunisian sheep samples. The average genomic inbreeding coefficients based on ROH were estimated at 0.017, 0.021, and 0.024 for Barbarine (BAR, n = 26), Noire de Thibar (NDT, n = 23), and Queue fine de l'Ouest (QFO, n = 14) breeds, respectively. The genomic relationships among individuals based on identity by state (I…
Experimental and quantum-chemical characterization of heavy carbon subchalcogenides: Infrared detection of SeC3Se
2021
Abstract High-resolution infrared studies of laser ablation products from carbon-selenium targets have revealed a new vibrational band at 2057 cm−1 that is identified as the ν 3 vibrational fundamental of the SeC3Se cluster. Because of the rich isotopic composition of selenium and the heavy nuclear masses involved, the vibrational band shows a relatively compact and complex structure despite the simple linear geometric arrangement. Overall, rotational-vibrational lines of six isotopologues could be assigned and fitted permitting the derivation of an accurate selenium-carbon bond length. Spectroscopic analysis has been greatly supported by high-level quantum-chemical calculations of the mol…
Chemical Composition and Broad-Spectrum Insecticidal Activity of the Flower Essential Oil from an Ancient Sicilian Food Plant, Ridolfia segetum
2021
Several species of the family Apiaceae are aromatic herbs that produce essential oils usable on an industrial scale for pharmaceutical, cosmetic, and food purposes. In particular, some essential oils, such as green insecticides for example, may replace synthetic insecticides, keeping most of their efficacy and avoiding environmental pollution or human poisoning. In the present study, we explored the insecticidal potential of Ridolfia segetum (L.) Moris essential oil (EO) against three different pests: Culex quinquefasciatus Say, Musca domestica L., and Spodoptera littoralis (Boisduval). For this purpose, the EO was obtained by hydrodistillation of flowers and its composition was achieved by…
Diversification des cultures, exemple de la lentille et biologie translationnelle
2021
National audience; Présentation de l'Atelier :Les protéines sont des macronutriments majeurs dans l’alimentation des hommes et des animaux. Or la production de protéines végétales est toujours déficitaire en France qui a recours à des importations pour couvrir ses besoins.Les légumineuses contiennent plus de protéines que les céréales. En outre, leur culture contribue à la mise en œuvre de systèmes moins demandeurs en intrants qui peuvent ainsi, seuls, en rotation ou en mélange, contribuer efficacement à la démarche one health, vers une meilleure santé globale des hommes, des animaux, des cultures et de l’environnement. Améliorer la qualité des protéines végétales, tout en maintenant voire …
Oxidative stress induced by the novel compound tributyltin(iv) ferulate promotes ER stress and autophagy in colon cancer cells
2021
Independent friction-restitution approach to analyze anomalies in normal kinematic restitution in oblique impact
2021
Abstract Oblique impact between rigid bodies is usually described in terms of the coefficients of normal and tangential restitution. When the contact between bodies occurs under elasto-plastic conditions, the normal coefficient of restitution can be ordinarily taken as essentially constant. Several anomalous results reported by Louge and Adams (Anomalous behavior of normal kinematic restitution in the oblique impacts of a hard sphere on an elasto-plastic plate. Phys. Rev. E 65 (2002) 021303), however denoted a significant variation of this coefficient with the incidence angle under certain conditions. This anomalous behavior is interpreted here within the independent friction and restitutio…
253. La pandemia y el Geoforo Iberoamericano en 2020
2021
La pandemia de la COVID-19, que nos afecta desde los primeros meses de 2020, ha modificado nuestras costumbres y rutinas. Y también la manera de relacionarnos en los medios escolares y universitarios. Desde el Geoforo Iberoamericano sobre Educación, Geografía y Sociedad hemos considerado que se abría una oportunidad para re-pensar los problemas sociales y ambientales que condicionan nuestra cotidianidad. Desde el estudio de situaciones particulares hemos querido definir los problemas intelectuales que sean susceptibles de ser trabajados en las aulas. Esta consideración es fruto de la evolución que venimos manteniendo desde 2008 y que se valoró en el Coloquio de 2019 en Bogotá, del cual tamb…
(Trifluoromethoxy)Phenylboronic Acids: Structures, Properties, and Antibacterial Activity.
2021
Three isomers of (trifluoromethoxy)phenylboronic acids were studied in the context of their physicochemical, structural, antimicrobial and spectroscopic properties. They were characterized by 1H, 13C, 11B and 19F NMR spectroscopy. The acidity of all the isomers was evaluated by both spectrophotometric and potentiometric titrations. The introduction of the -OCF3 group influences the acidity, depending, however, on the position of a substituent, with the ortho isomer being the least acidic. Molecular and crystal structures of ortho and para isomers were determined by the single crystal XRD method. Hydrogen bonded dimers are the basic structural motives of the investigated molecules in the sol…
Integrated use of unmanned aerial vehicle photogrammetry and terrestrial laser scanning to support archaeological analysis: The Acropolis of Selinunt…
2021
Southwestern Sicily is an area of infrequent seismic activity; however, some studies carried out in the archaeological Selinunte site suggest that, between the fourth century BC and the early Middle Ages, probably at least two earthquakes strucked this area with enough energy to damage and cause the collapse and kinematics of much of the architecture of Selinunte. Take into account that, in 2008, a noninvasive archaeological prospection and traditional data gathering methods along the Acropolis north fortifications were carried out. Following these first studies, after about 10 years, a new geophysical campaign was carried out. This second campaign benefited from the application of modern t…
The use of MAP for maintaining quality of ‘Bifara’ fig fruits
2021
Bifara is an old cultivar of Sicilians breba fig (Ficus carica L.). Several studies on market trends and consumer preferences show that fresh fruit is required to have a good visual appearance and to be without defects on the skin in order to be considered fresh and healthy. Breba fig is a climacteric fruit that ripens very rapidly, and therefore, once harvested, it must be kept under low temperature. To reduce the respiration rate of this fruit and increase its postharvest life, effectiveness of low temperature storage was studied on ‘Bifara’ fig fruit, either placed in Modified Atmosphere Packaging MAP (20 kPa O2 and 15 kPa CO2) bags and stored for 3, 5, 7, and 10 days at 5°C and 90% RH. …
Study on consumer preferences for quality attributes of fig fruit after storage at room temperature
2021
Fig (Ficus carica L.) is a nutritious fruit, rich in fiber, potassium, calcium, and iron. It is an important source of vitamins, amino acids, antioxidants and phenolic compounds that contribute to a healthy diet. In addition to Asian countries, fig is cultivated in the Mediterranean basin, where quality fruit has been produced since ancient times. Sicily in southern Italy traditionally cultivated ‘San Giovanni’ figs, but fig consumption has decreased. This cultivar is very interesting for its intrinsic qualities and its appreciation after storage by consumers could help its commercialization. The objective of this study is to know consumer preferences for quality attributes of ‘San Giovanni…
The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection
2021
Summary Ebola virus (EBOV) is responsible for outbreaks with case fatality rates of up to 90% and for an epidemic in West Africa with more than ten thousand deaths. EBOV glycoprotein (EBOV-GP) is the only viral surface protein and is responsible for viral entry into cells. Here, by employing pseudotyped EBOV-GP viral particles, we uncover a critical role for sphingolipids in inhibiting viral entry. Sphingosine kinase 1 (SphK1) catalyzes the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P). The administration of the SphK1 activator, K6PC-5, or S1P, or the overexpression of SphK1 consistently exhibited striking inhibitory effects in EBOV-GP-driven entry in diverse cell lines. F…
Predictive Value of Pro-BNP for Heart Failure Readmission after an Acute Coronary Syndrome
2021
Background: N-terminal pro-brain natural peptide (NT-pro-BNP) is a well-established biomarker of tissue congestion and has prognostic value in patients with heart failure (HF). Nonetheless, there is scarce evidence on its predictive capacity for HF re-admission after an acute coronary syndrome (ACS). We performed a prospective, single-center study in all patients discharged after an ACS. HF re-admission was analyzed by competing risk regression, taking all-cause mortality as a competing event. Results are presented as sub-hazard ratios (sHR). Recurrent hospitalizations were tested by negative binomial regression, and results are presented as incidence risk ratio (IRR). Results: Of the 2133 …
Le répertoire d’un atelier d’ameublement parisien
2021
International audience
Comment on “Androgens and women: COVID‐19 outcomes in women with acne vulgaris, polycystic ovarian syndrome, and hirsutism”
2021
Nonsurgical treatment of an adult with skeletal Class III malocclusion, anterior crossbite, and an impacted canine
2021
Class III malocclusion presents some complexity in terms of diagnosis and treatment and affects not only the jaws but the whole craniofacial complex. Besides, functional forward displacement of the mandible may be diagnosed in a patient presenting Class III malocclusion, as the 2 entities are not incompatible or mutually exclusive. This case report describes the multidisciplinary, nonsurgical, orthodontic treatment of an adult patient with a skeletal Class III malocclusion, anterior crossbite, and a palatally impacted canine, treated with fixed appliances and skeletal anchorage. To upright the mandibular molars, distalize the whole mandibular arch, and avoid excessive inclination of maxilla…
Active biopackaging produced from by‐products and waste from food and marine industries
2021
The agro‐food industry cannot today do without packaging to preserve and above all market its products. Plastic materials coming mainly from petrochemicals have taken a predominant place in the food packaging sector. They have become indispensable in many sectors, from fresh to frozen products, from meat and dairy products to fruit and vegetables or almost‐ready meals. Plastics are cheap, their lightness reduces transport costs, and their convenience is fundamental for out‐of‐home catering. However, plastics pose serious end‐of‐life issues. The development of materials that are more respectful of the consumer and the environment has become a major issue. In addition, the agro‐food industrie…
Mal-logement des personnes âgées en France : des situations marginales à l’habitat inadapté
2021
numéro « Vieillissement, marginalité urbaine et mal-logement »; International audience
Outcomes of hospitalized patients with COVID-19 according to level of frailty
2021
Background The complications from coronavirus disease 2019 (COVID-19) have been the subject of study in diverse scientific reports. However, many aspects that influence the prognosis of the disease are still unknown, such as frailty, which inherently reduces resistance to disease and makes people more vulnerable. This study aimed to explore the complications of COVID-19 in patients admitted to a third-level hospital and to evaluate the relationship between these complications and frailty. Methods An observational, descriptive, prospective study was performed in 2020. A sample of 254 patients from a database of 3,112 patients admitted to a high-level hospital in Madrid, Spain was analyzed. …
Endometrial Receptivity Analysis (ERA): data versus opinions
2021
Abstract This article summarises and contextualises the accumulated basic and clinical data on the ERA test and addresses specific comments and opinions presented by the opponent as part of an invited debate. Progress in medicine depends on new technologies and concepts that translate to practice to solve long-standing problems. In a key example, combining RNA sequencing data (transcriptomics) with artificial intelligence (AI) led to a clinical revolution in personalising disease diagnosis and fostered the concept of precision medicine. The reproductive field is no exception. Translation of endometrial transcriptomics to the clinic yielded an objective definition of the limited time period …
Using a hazard-independent approach to understand road-network robustness to multiple disruption scenarios
2021
Abstract A range of predictable and unpredictable events can cause road perturbations, disrupting traffic flows and more generally the functioning of society. To manage this threat, stakeholders need to understand the potential impact of a multitude of predictable and unpredictable events. The present paper adopts a hazard-independent approach to assess the robustness (ability to maintain functionality despite disturbances) of the Sioux Falls network to all possible disruptions. This approach allows understanding the impact of a wide range of disruptive events, including random, localised, and targeted link failures. The paper also investigates the predictability of the link combinations wh…
Cardiac troponin elevation in patients with influenza virus infections
2021
The association between acute infections and cardiac injury, including myocarditis and acute myocardial infarction, is now well established. We have performed a systematic literature review for analyzing the results of epidemiological studies that measured cardiac troponins (cTn) in patients with Influenza virus infections. Overall, 14 articles were finally identified and analyzed. Taken together, the results of the scientific literature suggest that cTn elevation is a relatively rare phenomenon in patients with Influenza virus infection, with frequency generally comprised between 0 and 33%, more likely in elderly patients with significant comorbidities. In patients with modest cTn elevatio…
Effectiveness and efficiency of a special program to reduce the bariatric surgery waiting list at a tertiary hospital
2021
Graphical abstract
Design of a safety training package for migrant workers in the construction industry
2021
Abstract The construction sector is known as a high-risk sector with many safety challenges. It is also characterised by a large number of migrant workers and these workers report higher accident rates than native workers. This paper presents the design of the CSTP (Construction Safety Training Programme). The CSTP is a theory-based training program aimed at improving safety behaviours in construction sites acknowledging the particular challenges migrant workers face. Based on second and third generational models of training, we developed a training program that addresses the challenges faced by migrant workers in the construction industry, namely language and cultural barriers, times press…
Credit and financial markets in the Iberian Peninsula at the end of the Middle Ages. Historiographic production and recent developments
2021
El artículo examina la trayectoria de los estudios sobre el crédito y los mercados financieros en la Península Ibérica a finales de la Edad Media, desde los primeros trabajos sobre la usura y el préstamo a interés, fundamentalmente judío, en la primera mitad del siglo XX, hasta las líneas de investigación más recientes, que se ramifican en diversas direcciones, desde el marco teórico, doctrinal y legal del mercado del crédito y el estudio de los diferentes instrumentos financieros –préstamo a interés, crédito comercial y bancario, crédito a largo plazo en forma de censales y censos consignativos– a la deuda pública y el crédito privado, especialmente el crédito rural. Todos estos estudios m…
A “nucleophilic” iodine in a halogen-bonded iodonium complex manifests an unprecedented I+···Ag+ interaction
2021
Summary When an electron is removed from a halogen atom, it forms a halenium ion X+ (X = I, Br, Cl). In halogen bonding (XB), X+ is considered as a strong XB donor, and when interacting with two XB acceptors (e.g., pyridine), it forms a halonium XB complex with a [N–I–N] three-center-four-electron bond with the two XB acceptors. An unprecedented I+···Ag+ interaction occurs between a [L1–I–L1]+ halogen-bonded complex and a [L2–Ag–L2]+ complex in which the iodonium ion acts like a nucleophile and donates electrons to the silver(I) cation. The X-ray diffraction analysis reveals a short contact [3.4608(3) A] between the I+ and Ag+ cations, and ITC measurements give a ΔG of −6.321 kcal/mol and K…
Un Parco nella Sicilia più nascosta
2021
Le aree interne della Sicilia sono caratterizzate, oltre che dalle tipiche crisi delle aree marginali, da altri fattori peculiari quali una costante arretratezza tecnologica e uno disfattismo di gattopardesca memoria. Esse sono anche però il luogo ove lo sviluppo locale potrebbe riportare i suoi migliori esiti, trasformandole da luoghi del sottosviluppo in luoghi di rinnovata e viva identità. Ciò in virtù dalla immensa potenzialità che luoghi naturali come i Parchi possiedono intrinsecamente per avviare uno sviluppo sostenibile che riesca a mantenere le componenti identitarie e paesaggistiche di un luogo e al contempo risollevarne le sorti. Il caso studio, ivi presentato, riguarda il Parco …
Postharvest quality and sensory attributes of organically grown Ficus carica L.
2021
This study evaluates some physical and chemical characteristics and sensory descriptors of fig fruit cultivars ‘Petrelli’ and ‘Fico di Terlizzi’, belonging to the national germplasm bank of fig trees and cultivated in Southern Italy. For the sensory evaluation of external appearance, the descriptors skin color, pulp color, odor, sweetness, stickiness, bitterness, juiciness, firmness, tannic taste and presence of achenes were measured. Results showed that fresh weight, total soluble solids (TSS), titratable acidity (TA), TSS:TA, firmness, and sensory properties were different for the two cultivars. SSC was more correlated with sensory attributes than TA, but other factors were also important…
Poola intertekstuaalsed meemid COVID pandeemia kohta
2021
The aim of the paper is to show the Polish story of the COVID-19 pandemic as seen through a humorous looking glass. Different stages of coronavirus presence in the media and social discourse have been accompanied by the appearance and development of jokes and memes, which illustrate the rapidly changing pandemic situation. The database consists of over three hundred memes, movies, and comments collected between February and May 2020, during the pandemic humour peak, and come mainly from private WhatsApp and Facebook accounts of the researchers. The humorous material is related to introduced restrictions, changing laws, parliamentary elections, news from other affected countries as well as s…
A ventral striatal prediction error signal in human fear extinction learning.
2021
Animal studies have shown that the prediction error (PE) signal that drives fear extinction learning is encoded by phasic activity of midbrain dopamine (DA) neurons. Thus, the extinction PE resembles the appetitive PE that drives reward learning. In humans, fear extinction learning is less well understood. Using computational neuroimaging, a previous study from our group reported hemodynamic activity in the left ventral putamen, a subregion of the ventral striatum (VS), to correlate with a PE function derived from a formal associative learning model. The activity was modulated by genetic variation in a DA-related gene. To conceptually replicate and extend this finding, we here asked whether…
Optimal use of lipid-lowering therapy after acute coronary syndromes: A Position Paper endorsed by the International Lipid Expert Panel (ILEP)
2021
Atherosclerotic cardiovascular disease (ASCVD) and consequent acute coronary syndromes (ACS) are substantial contributors to morbidity and mortality across Europe. Much of these diseases burden is modifiable, in particular by lipid-lowering therapy (LLT). Current guidelines are based on the sound premise that with respect to low density lipoprotein cholesterol (LDL-C), “lower is better for longer”, and the recent data have strongly emphasized the need of also “the earlier the better”. In addition to statins, which have been available for several decades, the availability of ezetimibe and inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9) are additional very effective approa…
Behavioral Restriction Determines Left Attentional Bias: Preliminary Evidences From COVID-19 Lockdown
2021
International audience; During the COVID-19 lockdown, individuals were forced to remain at home, hence severely limiting the interaction within environmental stimuli, reducing the cognitive load placed on spatial competences. The effects of the behavioral restriction on cognition have been little examined. The present study is aimed at analyzing the effects of lockdown on executive function prominently involved in adapting behavior to new environmental demands. We analyze non-verbal fluency abilities, as indirectly providing a measure of cognitive flexibility to react to spatial changes. Sixteen students (mean age 20.75; SD 1.34), evaluated before the start of the lockdown (T1) in a battery…