showing 36 of ~574560 from 574555 documents

Identifying Past and Current Trends in Technology Education in Finland

2021

Technology education makes a unique contribution to the development of all young people by providing them a wide range of knowledge and skills. It has a role in shaping future debates and discourses by developing students’ technological literacy and by raising awareness of various dimensions of technology. In order to understand technology education in Finnish basic education, it is necessary to consider it within the subject of craft, particularly the domain of technical craft activities. However, the role of technology education has been and still is undefined in Finland. Thus, we need strategic planning and research in order to develop the necessary procedures and operations to achieve i…

perusopetusteknologiakasvatusComputingMilieux_COMPUTERSANDEDUCATIONteknologia516 Educational sciencesopetusopetussuunnitelmat

A Monomeric Aluminum Imide (Iminoalane) with Al–N Triple-Bonding: Bonding Analysis and Dispersion Energy Stabilization

2021

The reaction of :AlAriPr8 (AriPr8 = C6H-2,6-(C6H2-2,4,6-iPr3)2-3,5-iPr2) with ArMe6N3 (ArMe6 = C6H3-2,6-(C6H2-2,4,6-Me3)2) in hexanes at ambient temperature gave the aluminum imide AriPr8AlNArMe6 (1). Its crystal structure displayed short Al–N distances of 1.625(4) and 1.628(3) Å with linear (C–Al–N–C = 180°) or almost linear (C–Al–N = 172.4(2)°; Al–N–C = 172.5(3)°) geometries. DFT calculations confirm linear geometry with an Al–N distance of 1.635 Å. According to energy decomposition analysis, the Al–N bond has three orbital components totaling −1350 kJ mol–1 and instantaneous interaction energy of −551 kJ mol–1 with respect to :AlAriPr8 and ArMe6N̈:. Dispersion accounts for −89 kJ mol–1, …

kemialliset yhdisteetCommunicationChemical SciencesGeneral ChemistrykompleksiyhdisteetalumiiniJournal of the American Chemical Society

Credit and financial markets in the Iberian Peninsula at the end of the Middle Ages. Historiographic production and recent developments

2021

El artículo examina la trayectoria de los estudios sobre el crédito y los mercados financieros en la Península Ibérica a finales de la Edad Media, desde los primeros trabajos sobre la usura y el préstamo a interés, fundamentalmente judío, en la primera mitad del siglo XX, hasta las líneas de investigación más recientes, que se ramifican en diversas direcciones, desde el marco teórico, doctrinal y legal del mercado del crédito y el estudio de los diferentes instrumentos financieros –préstamo a interés, crédito comercial y bancario, crédito a largo plazo en forma de censales y censos consignativos– a la deuda pública y el crédito privado, especialmente el crédito rural. Todos estos estudios m…

HistoryCreditHistòria medievalmedia_common.quotation_subjectGeography Planning and DevelopmentHumanidadesUsuryHistoriaDebtHM401-1281CréditoUsuryPeninsulaDeudaDebtEconomicsSociology (General)Middle AgesPréstamomedia_commongeographygeography.geographical_feature_categoryFinancial instrumentWelfare economicsFinancial marketFinanzasAgricultural and Biological Sciences (miscellaneous)UsuraLoanUrban StudiesEuropeAgrarian societyFinancesIndustrial relationsBond marketEuropaSocial history and conditions. Social problems. Social reformHN1-995

Photoelastic analysis of conventional and locking system for treatment of mandibular angle fractures with a single plate

2021

Made available in DSpace on 2021-06-25T10:28:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01 Background: This photoelastic analysis evaluated stress distribution in different osteosynthesis systems, conventional and locking, used for treatment of mandibular angle fractures with a single plate. Material and Methods: Angle fractures were simulated in mandibles made of photoelastic resin. Following Champy’s method, plate osteosynthesis was performed. The samples were divided into five groups: Group 1, non-fractured mandible; Group 2, two screws were installed in each segment using a conventional system; Group 3, two screws were installed in each segment using a locking system; …

OrthodonticsPhotoelasticityUniversal testing machineOsteosynthesisMaterials scienceResearchMandibular fractureMandibleInternal fracture fixation030206 dentistrymedicine.diseaseMandibular first molarbone platesStress (mechanics)03 medical and health sciences0302 clinical medicinemandibular fractureBone platemedicineOral Surgery030223 otorhinolaryngologyosteosynthesisGeneral DentistryUNESCO:CIENCIAS MÉDICAS

Effectiveness and efficiency of a special program to reduce the bariatric surgery waiting list at a tertiary hospital

2021

Graphical abstract

medicine.medical_specialtyIMC índice de masa corporalSIGE servicio de información y gestión económicaBAGUA bypass gástrico de una anastomosisLEQ lista de espera quirúrgica030230 surgeryQA quirófano de autoconciertoArticleQP quirófano programadoStandard procedure03 medical and health sciences0302 clinical medicineSalud públicaHealth careEpidemiologymedicineGRD grupos relacionados con el diagnósticoBGYR bypass gástrico en Y de RouxProspective cohort studySWL surgical waiting listAverage costComputingMethodologies_COMPUTERGRAPHICSCirugía bariátricaBariatric surgeryPublic healthWaiting listsbusiness.industryGeneral EngineeringPerioperativeAC autoconciertosSECO Sociedad Española de Cirugía de ObesidadSurgeryCoste y análisis de costesListas de esperaWaiting listCosts and cost analysisGV gastrectomía verticalbusinessHealthcare systemCirugía Española (English Edition)

COMPAS : une application innovante pour soutenir la communication centrée sur la personne entre les personnes âgées atteintes de démence et leur proc…

2021

Introduction Les personnes atteintes de demence (PAD) developpent des troubles de la communication qui impactent la relation avec l’aidant ce qui contribue a l’isolement de l’un et a l’epuisement de l’autre. Objectifs L’objectif est de valider COMmunication Proche-Aidants (COMPAs) en contexte de soins de longue duree. Cette application favorise les interactions grâce a du contenu audiovisuel personnalise permettant une communication centree sur la personne. Patients et methodes 17 aides-soignants ont utilise quotidiennement COMPAs aupres de 39 beneficiaires atteints de troubles neurocognitifs majeurs pendant huit semaines. L’etude mesure les effets de COMPAs sur la communication, la qualite…

NeurologyNeurology (clinical)Revue Neurologique

Semantics of Voids within Data: Ignorance-Aware Machine Learning

2021

Operating with ignorance is an important concern of geographical information science when the objective is to discover knowledge from the imperfect spatial data. Data mining (driven by knowledge discovery tools) is about processing available (observed, known, and understood) samples of data aiming to build a model (e.g., a classifier) to handle data samples that are not yet observed, known, or understood. These tools traditionally take semantically labeled samples of the available data (known facts) as an input for learning. We want to challenge the indispensability of this approach, and we suggest considering the things the other way around. What if the task would be as follows: how to buil…

luokitus (toiminta)paikkatiedotlcsh:G1-922data miningprototype selectionignorancekoneoppiminenclassificationdata semanticstiedonlouhintaadversarial learningdata voidslcsh:Geography (General)ISPRS International Journal of Geo-Information

Children of migrants in French and Norwegian schools. A comparative analysis of educational attainment of second-generation students and reflections …

2021

International audience

SchoolChildren of migrantNorway[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationComparative analysisFranceequalityEducational attainmentsecond-generation studentComputingMilieux_MISCELLANEOUS

Artritis séptica por Sneathia sanguinegens en un varón. Primer caso descrito en la literatura científica

2021

Resumen Varon de 88 anos que ingresa por artritis septica de hombro por un bacilo Gram negativo. Se identifica el microorganismo mediante secuenciacion del gen 16 S ADNr como Sneathia sanguinegens. Se trata del primer caso descrito en la literatura en un varon, ya que hasta el momento solo se habian descrito infecciones en mujeres en edad fertil.

RheumatologyReumatología Clínica

Changes in Brand-Related Consumer Loyalty in the Current Pandemic Context

2021

Abstract The current medical crisis and, implicitly, the economic one, generated by the Covid-19 pandemic have brought increased attention to the issue of brand-related consumer loyalty, as loyal consumers are the safest and most stable source of profit in the current economic and social context. It is well-known that there is no equality between the notions of consumer satisfaction and loyalty. The two notions are not synonymous, as consumer satisfaction is only a relative, but not sufficient condition to obtain consumer loyalty. This paper aims to take a systemic approach in discussing the issue of brand-related consumer loyalty, starting from the inputs, respectively the favorable factor…

HF5001-6182Social PsychologyConsumer loyaltymedia_common.quotation_subject05 social sciencesEconomics Econometrics and Finance (miscellaneous)consumer satisfactionSocial environmentContext (language use)Secondary databrand equityProfit (economics)Order (business)0502 economics and businessLoyaltyPandemicBusiness Management and Accounting (miscellaneous)Business050211 marketingBusinessrelational marketingMarketing050212 sport leisure & tourismbrand loyaltymedia_commonStudies in Business and Economics

A criterion for extending morphisms from open subsets of smooth fibrations of algebraic varieties

2021

Abstract Given a smooth morphism Y → S and a proper morphism P → S of algebraic varieties we give a sufficient condition for extending an S-morphism U → P , where U is an open subset of Y, to an S-morphism Y → P , analogous to Zariski's main theorem.

Smooth morphismPure mathematicsAlgebra and Number TheoryAlgebraic varietySmooth fibrationZariski’s main theoremFiberwise birational morphismProper morphismMathematics::Algebraic GeometryMorphismExtending a morphismMathematics::Category TheorySettore MAT/03 - GeometriaMathematicsJournal of Pure and Applied Algebra

Study on the Reputation of the (MASS) Media in Romania

2021

Abstract Part of a bigger research project conducted by Media Reputation Lab (Media REP Lab) on the reputation of media in Europe, the study explores the reputation of media among informed population in Romania. A sample of 100 cases was involved in the online survey taking place in December 2019. The results provide a description of the country’s media reputation (media in general: radio, print, digital and television). For each one of these media, the valuation obtained by each of the reputational attributes (credibility, rigor, impartiality, willingness to rectify) by the informed population would be indicated. Moreover, insights on the knowledge and use, as well as on the reputation (ov…

key reputation aspectsSocial PsychologyHF5001-6182business.industrymedia_common.quotation_subject05 social sciencesEconomics Econometrics and Finance (miscellaneous)050801 communication & media studies020207 software engineeringAdvertisingreputation02 engineering and technologymass media0508 media and communicationsPolitical science0202 electrical engineering electronic engineering information engineeringBusiness Management and Accounting (miscellaneous)reputational attributesBusinessbusinessromaniaMass mediaReputationmedia_commonStudies in Business and Economics

Optimal use of lipid-lowering therapy after acute coronary syndromes: A Position Paper endorsed by the International Lipid Expert Panel (ILEP)

2021

Atherosclerotic cardiovascular disease (ASCVD) and consequent acute coronary syndromes (ACS) are substantial contributors to morbidity and mortality across Europe. Much of these diseases burden is modifiable, in particular by lipid-lowering therapy (LLT). Current guidelines are based on the sound premise that with respect to low density lipoprotein cholesterol (LDL-C), “lower is better for longer”, and the recent data have strongly emphasized the need of also “the earlier the better”. In addition to statins, which have been available for several decades, the availability of ezetimibe and inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9) are additional very effective approa…

0301 basic medicineRMmedicine.medical_specialtyCombination therapyPCSK9 inhibitoreffectivenessTreatment goalsLipid-lowering therapy03 medical and health sciences0302 clinical medicineEzetimibemedicineHumansAcute Coronary SyndromeCombination therapyIntensive care medicinePharmacologyStatins.business.industryAtherosclerotic cardiovascular diseaseAnticholesteremic AgentsPCSK9StatinsEffectiveneDisease ManagementAtherosclerosisEzetimibeLipids030104 developmental biologyPCSK9 inhibitors030220 oncology & carcinogenesisPosition paperSafetybusinessVery high riskmedicine.drug

Neutropenia tóxica tras ocrelizumab sin recurrencias posteriores tras continuar el tratamiento

2021

business.industryMedicineNeurology (clinical)businessNeurology Perspectives

Childhood cancer:Survival, treatment modalities, late effects and improvements over time

2021

Since the 1960s, paediatric oncologists have gradually become better organised in large study groups and participation in clinical trials is today considered as the standard of care, with most children with cancer in Europe and North America being enrolled on available treatment protocols. Chemotherapy is nowadays the main element of therapy, but irradiation is still required for some patients. With the advent of multimodality therapy and supportive care, five-year cancer survival exceeds 80 % in most European and North American countries today. The substantial improvements in survival led to a constantly growing population of childhood cancer survivors. Concerns regarding the risk of late …

Cancer Researchmedicine.medical_specialtyTime FactorsSurvivalEpidemiologyPopulationMultimodality TherapySurvivorshipSocial and socioeconomic conditions03 medical and health sciencesSomatic late effects0302 clinical medicineQuality of life (healthcare)NeoplasmsSurvivorship curvemedicineHumans030212 general & internal medicineChild610 Medicine & healthIntensive care medicineeducationSocioeconomic statusClinical Trials as Topiceducation.field_of_studybusiness.industryCancerTemporal changesmedicine.diseaseCombined Modality TherapySurvival AnalysisMental healthSurvivor cohortsEuropeClinical trialTreatment OutcomeOncology030220 oncology & carcinogenesisCancer treatmentNorth AmericaMental late effectsbusinessChildhood cancer360 Social problems & social services

The role of the brand in perceived service performance: Moderating effects and configurational approach in professional football

2021

Abstract This research aims to determine the effects of brand credibility and brand congruence on future intentions, perceived value, and spectators’ satisfaction among the fans of a first division football team by combining two complementary methodological approaches, lineal models (the PROCESS macro) and fuzzy set qualitative comparative analysis (fsQCA). The effects of brand credibility and brand congruence were tested in a sample of 536 fans of a first division Spanish football club aged from 18 to 70 (70.2% men). The results suggest direct, positive, and significant effects of brand congruence and brand credibility on perceived value and future intentions. In contrast, in predicting sp…

Qualitative comparative analysis020209 energy05 social sciences02 engineering and technologyFootballFootball clubFootball teamManagement of Technology and Innovation0502 economics and businessCredibility0202 electrical engineering electronic engineering information engineeringBusiness and International ManagementSport managementPsychologySocial psychology050203 business & managementApplied PsychologyTechnological Forecasting and Social Change

Violence against women: An observational study in an Italian emergency department

2021

Abstract Violence against women is a pervasive phenomenon affecting one in three women aged ≥15 in the world that are more likely to visit an emergency department (ED) for the serious physical and psychological consequences of the abuse. The aim of this observational single-centre study is to describe the socio-demographic and clinical variables associated with violence against women. We enrolled 425 female patients who attended an Italian ED for trauma on 2019 and the patients' information was collected and analyzed with descriptive statistics. The average age of the patients was 41.5 (standard deviation = 14.2) years. 74.6% of the women were Italians, and 86.6% were of metropolitan origin…

Adultmedicine.medical_specialtyMultivariate analysisAdolescentWomen's healthProtective factorViolenceYoung Adult03 medical and health sciences0302 clinical medicineEthnicitymedicineHumans030212 general & internal medicineCrime VictimsGeneral Nursing030504 nursingAggressionbusiness.industryGenderEmergency departmentOdds ratioMiddle AgedSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheConfidence intervalItalyFamily medicineAccidentalFemaleObservational studymedicine.symptomEmergency Service Hospital0305 other medical sciencebusiness

An Overview of Asthma and COVID-19: Protective Factors Against SARS-COV-2 in Pediatric Patients.

2021

Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by severe acute respiratory syndrome coronavirus SARS-COV-2. Aberrant innate immunity response and cytokine storm are responsible for the syndrome. Apparently, in asthmatic patients, the inadequate antiviral immune response and the tendency for asthma exacerbation evoked by common respiratory viruses could explain increased susceptibility to SARS-COV-2 infection. However, asthma has not been suggested to be a risk factor in COVID-19 patients. Therefore, in asthmatic patients some potential protective mechanisms against SARS-COV-2 have been hypothesized, like type 2 immune response, number of eosinophils, overproduct…

protective factorMini ReviewProtective factorPediatricsRJ1-570Type 2 immune response03 medical and health sciences0302 clinical medicineImmune systemSettore MED/38 - Pediatria Generale E Specialisticachildrenmedicine030212 general & internal medicineRisk factorAsthmaInnate immune systembusiness.industrySARS-CoV-2COVID-19asthmamedicine.diseaserespiratory tract diseases030228 respiratory systemInfectious disease (medical specialty)ImmunologyPediatrics Perinatology and Child HealthCytokine stormbusinessFrontiers in pediatrics

The First Biography of Jesus: Genre and Meaning in Mark's Gospel, Helen K. Bond, Eerdmans, 2020 (ISBN 978‐0‐8028‐7460‐3), xiii + 317 pp., hb $43

2021

Environmental EngineeringPhilosophymedia_common.quotation_subjectBiographyGospelMeaning (existential)TheologyIndustrial and Manufacturing Engineeringmedia_commonReviews in Religion & Theology

Is there a need to widely prescribe antibiotics in patients hospitalized with COVID-19?

2021

Highlights • Antibiotics were a main part of COVID-19 treatments during the first epidemic peak. • Bacterial coinfections seem to be rare, especially if no ICU transfer needed. • We studied the place of antibiotics and the impact on prognosis of patients. • Antibiotics were prescribed if more severe infection and has no impact on prognosis. • We think that antibiotic therapy must be not widely prescribed.

Male0301 basic medicineMicrobiology (medical)medicine.medical_specialtymedicine.drug_class030106 microbiologyAntibioticsInfectious and parasitic diseasesRC109-216Articlelaw.inventionHospitals University03 medical and health sciences0302 clinical medicinelawInternal medicinemedicineHumans030212 general & internal medicineMedical prescriptionPropensity ScoreAgedAged 80 and overUnivariate analysisbusiness.industrySARS-CoV-2Hazard ratioCOVID-19General MedicineMiddle AgedAntibiotic therapyPrognosisIntensive care unitConfidence intervalAnti-Bacterial AgentsCOVID-19 Drug TreatmentHospitalizationInfectious DiseasesRadiological weaponSARS-CoV2Propensity score matchingFemaleFrancebusinessInternational Journal of Infectious Diseases

Entrepreneurship Pedagogy

2021

With Latvia's education reforms, the demand for transversal skills in the education process has increased. Although there has been a growing call to educate pupils and students in a way that develops entrepreneurial skills, there is no defined methodology for how to do it, and the definitions of entrepreneurial skills and entrepreneurship pedagogy have no common foundation. This study, therefore, compiles research from various scientific publications and offers a theoretical framework for the concepts of entrepreneurial skill and entrepreneurial pedagogy. It also reviews the noble practices of diverse European countries and analyzes Latvia's higher education experience and examples of entre…

EntrepreneurshipPedagogyMindsetSociologyInternational Journal of Smart Education and Urban Society

Critical role of cardiac magnetic resonance in the diagnosis of left-dominant arrhythmogenic cardiomyopathy: A paradigmatic case in a recreational mi…

2021

medicine.medical_specialtySports cardiologyCardiac magnetic resonancebusiness.industryCardiomyopathyCase Reportmedicine.diseaseDefibrillatorInternal medicineDiagnosisCardiologyMedicineCardiology and Cardiovascular MedicinebusinessCardiac magnetic resonanceLEFT DOMINANTArrhythmiaHeartRhythm Case Reports

COVID-19 lockdown influence in the psychiatric emergencies: Drastic reduction and increase in severe mental disorders.

2021

medicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe Mental DisordersSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Physical DistancingMEDLINESeverity of Illness IndexRisk FactorsPsychiatric emergenciesMedicineHumansRegistriesEmergency Services Psychiatricbusiness.industryHealth PolicyMental DisordersCOVID-19General MedicinePatient Acceptance of Health CarePsychiatry and Mental healthSpainEmergency medicineQuarantineEmergenciesbusinessScientific LetterFacilities and Services UtilizationRevista de psiquiatria y salud mental

Su Dante. Un accenno dagli studi di Romano Guardini

2021

In occasione del centenario in onore del Nostro, sommo poeta Dante, il testo si presenta come un accenno dagli Studi Danteschi di Romano Guardini. Ripercorrendo il viaggio nei tre regni dell’aldilà l’autore ne ricorda gli incontri salienti, mostrando al lettore l’esaustiva corrispondenza fra l’interiorità del protagonista e l’esteriorità dei paesaggi attraversati. Un breve rinvio ai più ricchi volumi XIX/1 e XIX/2 dell’Opera Omnia guardiniana.

Guardini Dante Viaggio EssenzialeSettore M-PED/02 - Storia Della PedagogiaSettore M-PED/01 - Pedagogia Generale E Sociale

Comparative Analysis of Nuclear Matrix Elements of 0νβ+β+ Decay and Muon Capture in 106Cd

2021

Comparative analyses of the nuclear matrix elements (NMEs) related to the 0νβ+β+ decay of 106Cd to the ground state of 106Pd and the ordinary muon capture (OMC) in 106Cd are performed. This is the first time the OMC NMEs are studied for a nucleus decaying via positron-emitting/electron-capture modes of double beta decay. All the present calculations are based on the proton-neutron quasiparticle random-phase approximation with large no-core single-particle bases and realistic two-nucleon interactions. The effect of the particle-particle interaction parameter gpp of pnQRPA on the NMEs is discussed. In the case of the OMC, the effect of different bound-muon wave functions is studied. peerRevie…

particle-particle interaction parameterMaterials Science (miscellaneous)quasiparticle random-phase approximationBiophysicsbound-muon wave functionGeneral Physics and Astronomynuclear matrix elementshiukkasfysiikkanuclear double beta decayHigh Energy Physics::ExperimentPhysical and Theoretical Chemistrynuclear muon captureydinfysiikkaMathematical Physics

European Resuscitation Council Guidelines 2021: Adult advanced life support.

2021

These European Resuscitation Council Advanced Life Support guidelines, are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. This section provides guidelines on the prevention of and ALS treatments for both in-hospital cardiac arrest and out-of-hospital cardiac arrest.

AdultResuscitationConsensusCardiac arrest; resuscitation; comamedicine.medical_treatment[SDV]Life Sciences [q-bio]ResuscitationeducationMEDLINE030204 cardiovascular system & hematologyEmergency Nursing03 medical and health sciences0302 clinical medicineSettore MED/41 - ANESTESIOLOGIAmedicineHumansCardiopulmonary resuscitationComaComputingMilieux_MISCELLANEOUSbusiness.industry030208 emergency & critical care medicinemedicine.diseaseCardiac arrestPrognosisCardiopulmonary Resuscitation3. Good healthAdvanced life supportEmergency MedicineMedical emergencyCardiology and Cardiovascular MedicinebusinessOut-of-Hospital Cardiac ArrestResuscitation

Validation of the Marathon Motivation Scale in Chile

2021

The objective of this work was to validate the Marathon Motivation Scale (MOMS) for its application in the Chilean context. The study used a non-experimental, descriptive and transversal design. The sample was non-probability and intentional and was composed of 250 subjects (143 male and 104 female) runners who participated in the International Marathon of Viña del Mar with an average age of 29.8 (TD = 10.1) years. For the analysis of the data, an exploratory factorial analysis was carried out with free parameters, another one with seven factors fixed to the theoretical dimensions and a confirmatory factorial analysis with the items corresponding to the MOMS model. The validity and reliabil…

Scale (ratio)ValidityPhysical Therapy Sports Therapy and RehabilitationSample (statistics)Context (language use)010501 environmental sciences01 natural sciencesMotivation scale0502 economics and businessStatisticsEducación Física y Deportivalcsh:Sports medicinechilean validation0105 earth and related environmental sciencesFactorial model05 social sciencesSpanish versionmotivation scaleChilean validationTransversal designmarathonersFactorial analysislcsh:RC1200-1245PsychologyMarathoners050203 business & managementJournal of Human Sport and Exercise

Monitoring serologic response to single in ovo vaccination with an immune complex vaccine against infectious bursal disease in broilers

2021

Este artículo se encuentra disponible en la siguiente URL: https://www.sciencedirect.com/science/article/pii/S003257912100033X The infectious bursal disease (IBD) virus is one of the most resistant and prevalent virus worldwide in the poultry industry, being vaccination the main tool to control the disease. For this reason, consistent and uniform immunization of broiler flocks against IBD is necessary to avoid the disease spreading. The aim of this study was to apply and assess an epidemiologic mapping tool focused on the immunization by in ovo single broiler vaccination using an immune complex IBD vaccine. With this regard, 7,576 serum samples were collected from 603 broiler flocks raised …

Pollos - Inmunología.animal diseasesChickens - Vaccination.IBDAntigen-Antibody ComplexChick EmbryoAntibodies ViralIn ovobroilerInfectious bursal disease virusSerologyInfectious bursal diseaseGeoServerIMMUNOLOGY HEALTH AND DISEASEAnimalsMedicineSeroprevalenceAves de corral - Enfermedades.Poultry - Diseases.Pollos - Enfermedades.Poultry DiseasesOvumlcsh:SF1-1100business.industryViral VaccinesGeneral MedicineBirnaviridae Infectionsmedicine.diseasevaccinationVaccinationTiterImmunizationChickens - Diseases.ImmunologyChickens - Immunology.Animal Science and ZoologyELISAFlocklcsh:Animal culturePollos - Vacunación.businessChickens

Existence of two positive solutions for anisotropic nonlinear elliptic equations

2021

This paper deals with the existence of nontrivial solutions for a class of nonlinear elliptic equations driven by an anisotropic Laplacian operator. In particular, the existence of two nontrivial solutions is obtained, adapting a two critical point results to a suitable functional framework that involves the anisotropic Sobolev spaces.

Settore MAT/05 - Analisi MatematicaApplied MathematicsAnisotropic problem variational method positive solutions partial differential equationsAnalysis

Hepatoprotective effects of extracts, fractions and compounds from the stem bark of Pentaclethra macrophylla Benth: Evidence from in vitro and in viv…

2021

Abstract Aim To identify the bioactive hepatoprotective components of the ethanol extract of Pentaclethra macrophylla stem bark using in vitro and in vivo approaches. Methods The bioguided-fractionation of the ethanol extract was based on the substances’ capacity to prevent in vitro, the lipid peroxidation of hepatocytes’ membranes induced by hydrogen peroxide. For the in vivo hepatoprotective test, mice were treated orally with the ethyl acetate (EtOAc) fraction of the ethanol extract at doses of 50 and 75 mg/kg/day for one week and subjected to d -galactosamine/lipopolysaccharide (GaIN/LPS)-induced hepatotoxicity. Blood samples were collected for alanine aminotransferase (ALAT), aspartate…

0301 basic medicineAntioxidantPentaclethra macrophyllaIsolated compoundsmedicine.medical_treatmentInterleukin-1betaLipid peroxidationStructure-activity relationshipsRM1-950AntioxidantsLipid peroxidationSuperoxide dismutase03 medical and health scienceschemistry.chemical_compoundMice0302 clinical medicineIn vivomedicineAnimalsAspartate AminotransferasesRats WistarPharmacologybiologyTraditional medicinePlant StemsChemistryPlant ExtractsTumor Necrosis Factor-alphaBergeninAlanine TransaminaseFabaceaeGeneral MedicineGlutathioneDisease Models Animal030104 developmental biologyHepatoprotectionLiverCatalase030220 oncology & carcinogenesisbiology.proteinHepatocytesPlant BarkTherapeutics. PharmacologyChemical and Drug Induced Liver InjuryGaIN/LPSHepatoprotectionBiomedicine & Pharmacotherapy

Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis : A longitudinal study of 1893 biopsy-proven no…

2021

[Background and Aim] Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) features, which is one of the leading causes of screening failure in clinical trials. We assessed the NASH distribution and its components across the fibrosis stages and their impact on the prognosis and their relationship with the concept of metabolic-associated fatty liver disease (MAFLD).

Liver Cirrhosismedicine.medical_specialtyCirrhosisSteatosisBiopsyGastroenterologydigestive systemBallooning03 medical and health sciencesLiver disease0302 clinical medicineNon-alcoholic Fatty Liver DiseaseFatty liver diseaseInternal medicineBiopsyNonalcoholic fatty liver diseasemedicineassociated fatty liver diseaseMetabolic-associated fatty liver diseaseHumansmetabolic&#8208Longitudinal StudiesFirst episodeInflammationHepatologymedicine.diagnostic_testballooning fatty liver disease inflammation metabolic-associated fatty liver disease natural coursesteatohepatitis steatosisbusiness.industryFatty liverNatural coursesteatohepatitismedicine.diseasedigestive system diseasesLiver030220 oncology & carcinogenesis030211 gastroenterology & hepatologySteatosisSteatohepatitisbusiness

Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesions.

2021

Summary VLGR1 (very large G protein-coupled receptor-1) is by far the largest adhesion G protein-coupled receptor in humans. Homozygous pathologic variants of VLGR1 cause hereditary deaf blindness in Usher syndrome 2C and haploinsufficiency of VLGR1 is associated with epilepsy. However, its molecular function remains elusive. Herein, we used affinity proteomics to identify many components of focal adhesions (FAs) in the VLGR1 interactome. VLGR1 is localized in FAs and assembles in FA protein complexes in situ. Depletion or loss of VLGR1 decreases the number and length of FAs in hTERT-RPE1 cells and in astrocytes of Vlgr1 mutant mice. VLGR1 depletion reduces cell spread and migration kinetic…

0301 basic medicineBiomoleculesMultidisciplinaryChemistryScienceQCell02 engineering and technologyCell Biology021001 nanoscience & nanotechnologyProteomicsInteractomeArticleCell biologyFocal adhesion03 medical and health sciences030104 developmental biologyMetabotropic receptormedicine.anatomical_structuremedicine0210 nano-technologyHaploinsufficiencyReceptorMolecular BiologyG protein-coupled receptoriScience

The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research

2021

Abstract Mycotoxins are fungal metabolites that can cause various diseases in humans and animals. The adverse health effects of mycotoxins such as liver failure, immune deficiency, and cancer are well-described. However, growing evidence suggests an additional link between these fungal metabolites and neurodegenerative diseases. Despite the wealth of these initial reports, reliable conclusions are still constrained by limited access to human patients and availability of suitable cell or animal model systems. This review summarizes knowledge on mycotoxins associated with neurodegenerative diseases and the assumed underlying pathophysiological mechanisms. The limitations of the common in vivo…

business.industryClinical BiochemistryFungiLiver failureNeurotoxicityfood and beveragesNeurodegenerative DiseasesMycotoxinsBioinformaticsmedicine.diseaseBiochemistryLimited accesschemistry.chemical_compoundAnimal modelchemistryAdverse health effectAnimalsHumansMedicinebusinessMycotoxinMolecular BiologyBiological Chemistry

Advance Directives. Comparison of current legislation within the European Union

2021

Abstract Advance Directives have been legally binding in Spain since the publication of Act 41/2002, of 14th November, which regulates patients’ rights to autonomy and obligations concerning clinical information and recording clinical information. However, the situation in each country of the European Union remains heterogeneous and unknown to most health care professionals. By collecting and studying the legislation on patients' rights in European Union countries we have made an updated comparison of the different features of Advance Directives in each country. Only 15 of the 28 European Union Countries have developed specific rules on advance directives which makes them legally binding in…

Revocationbusiness.industrymedia_common.quotation_subjectLegislationConsensus theory030204 cardiovascular system & hematologyDirectiveOfficer03 medical and health sciences0302 clinical medicineLawPolitical scienceHealth caremedia_common.cataloged_instance030216 legal & forensic medicineEuropean unionbusinessAutonomymedia_commonSpanish Journal of Legal Medicine

Prompt Determination of the Mechanical Properties of Industrial Polypropylene Sandwich Pipes

2021

A simple and prompt method to determine the mechanical properties of industrial multilayer extrusion polypropylene pipes for a gravity sewer network is suggested. The engineering formulas included for calculating the permissible thickness and relative position of a foam core in the pipes are based on a linear-elastic approximation and the rule of mixtures. The applicability of the approximation was justified experimentally during investigation of the effective tensile characteristics of single- and multilayer pipes and each layer specimen by using traditional tests and finite-element calculations. The results obtained were used to formulate engineering recommendations for calculations of th…

ultimate strengthTechnologyMaterials scienceCore (manufacturing)02 engineering and technologyArticlechemistry.chemical_compound0203 mechanical engineeringPosition (vector)Ultimate tensile strengthGeneral Materials ScienceComposite materialPolypropyleneMicroscopyQC120-168.85polypropylene pipesTQH201-278.5multilayer pipesexperimental tests021001 nanoscience & nanotechnologyEngineering (General). Civil engineering (General)TK1-9971020303 mechanical engineering & transportschemistryDescriptive and experimental mechanicsExtrusionElectrical engineering. Electronics. Nuclear engineeringTA1-20400210 nano-technologyFE analysisRule of mixturesMaterials

Microbiological Stability of Bio-Based Building Materials

2021

The aim of this paper was to study the microbiological stability of bio-based composite building materials, which are made using organic-rich lake sediments (further – sapropel) with lime and magnesium cement as binders and hemp shives as filler. The microbial stability properties of the obtained composite materials were investigated and compared to similar composites. Because of their high organic content, these materials are prone to biodegradation; therefore, they were coated with ALINA LIFE TM organoclay coating, which helps to extend the product life, reducing the rate of biodegradation compared to the biocides used in industry. The effect of the coating on the resistance to decay by t…

lcsh:GE1-350magnesium cementBio basedmicrobial stabilitybiocideslcsh:TD1-1066sapropellime-hemp materialsorganoclay additiveEnvironmental scienceBiochemical engineeringlcsh:Environmental technology. Sanitary engineeringEcology Evolution Behavior and Systematicslcsh:Environmental sciencesGeneral Environmental ScienceJournal of Ecological Engineering